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Items: 1 to 50 of 260

1.

Development of novel NEMO-binding domain mimetics for inhibiting IKK/NF-κB activation.

Zhao J, Zhang L, Mu X, Doebelin C, Nguyen W, Wallace C, Reay DP, McGowan SJ, Corbo L, Clemens PR, Wilson GM, Watkins SC, Solt LA, Cameron MD, Huard J, Niedernhofer LJ, Kamenecka TM, Robbins PD.

PLoS Biol. 2018 Jun 11;16(6):e2004663. doi: 10.1371/journal.pbio.2004663. eCollection 2018 Jun.

2.

Identifying Novel Signaling Pathways: An Exercise Scientists Guide to Phosphoproteomics.

Wilson GM, Blanco R, Coon JJ, Hornberger TA.

Exerc Sport Sci Rev. 2018 Apr;46(2):76-85. doi: 10.1249/JES.0000000000000146.

PMID:
29346157
3.

Multi-omics Reveal Specific Targets of the RNA-Binding Protein Puf3p and Its Orchestration of Mitochondrial Biogenesis.

Lapointe CP, Stefely JA, Jochem A, Hutchins PD, Wilson GM, Kwiecien NW, Coon JJ, Wickens M, Pagliarini DJ.

Cell Syst. 2018 Jan 24;6(1):125-135.e6. doi: 10.1016/j.cels.2017.11.012. Epub 2017 Dec 13.

PMID:
29248374
4.

Hsp70's RNA-binding and mRNA-stabilizing activities are independent of its protein chaperone functions.

Kishor A, White EJF, Matsangos AE, Yan Z, Tandukar B, Wilson GM.

J Biol Chem. 2017 Aug 25;292(34):14122-14133. doi: 10.1074/jbc.M117.785394. Epub 2017 Jul 5.

PMID:
28679534
5.

Helping Babies Breathe implementation in Zanzibar, Tanzania.

Wilson GM, Ame AM, Khatib MM, Rende EK, Hartman AM, Blood-Siegfried J.

Int J Nurs Pract. 2017 Aug;23(4). doi: 10.1111/ijn.12561. Epub 2017 Jun 19.

PMID:
28631394
6.

AUF1 regulation of coding and noncoding RNA.

White EJ, Matsangos AE, Wilson GM.

Wiley Interdiscip Rev RNA. 2017 Mar;8(2). doi: 10.1002/wrna.1393. Epub 2016 Sep 13. Review.

7.

Development and Implementation of a High-Throughput High-Content Screening Assay to Identify Inhibitors of Androgen Receptor Nuclear Localization in Castration-Resistant Prostate Cancer Cells.

Johnston PA, Nguyen MM, Dar JA, Ai J, Wang Y, Masoodi KZ, Shun T, Shinde S, Camarco DP, Hua Y, Huryn DM, Wilson GM, Lazo JS, Nelson JB, Wipf P, Wang Z.

Assay Drug Dev Technol. 2016 May;14(4):226-39. doi: 10.1089/adt.2016.716.

8.

Cleavage and polyadenylation specificity factor 30: An RNA-binding zinc-finger protein with an unexpected 2Fe-2S cluster.

Shimberg GD, Michalek JL, Oluyadi AA, Rodrigues AV, Zucconi BE, Neu HM, Ghosh S, Sureschandra K, Wilson GM, Stemmler TL, Michel SL.

Proc Natl Acad Sci U S A. 2016 Apr 26;113(17):4700-5. doi: 10.1073/pnas.1517620113. Epub 2016 Apr 11.

9.

Novel RNA-binding activity of MYF5 enhances Ccnd1/Cyclin D1 mRNA translation during myogenesis.

Panda AC, Abdelmohsen K, Martindale JL, Di Germanio C, Yang X, Grammatikakis I, Noh JH, Zhang Y, Lehrmann E, Dudekula DB, De S, Becker KG, White EJ, Wilson GM, de Cabo R, Gorospe M.

Nucleic Acids Res. 2016 Mar 18;44(5):2393-408. doi: 10.1093/nar/gkw023. Epub 2016 Jan 26.

10.

Tristetraprolin induces cell cycle arrest in breast tumor cells through targeting AP-1/c-Jun and NF-κB pathway.

Xu L, Ning H, Gu L, Wang Q, Lu W, Peng H, Cui W, Ying B, Ross CR, Wilson GM, Wei L, Wold WS, Liu J.

Oncotarget. 2015 Dec 8;6(39):41679-91. doi: 10.18632/oncotarget.6149.

11.

HCS campaign to identify selective inhibitors of IL-6-induced STAT3 pathway activation in head and neck cancer cell lines.

Johnston PA, Sen M, Hua Y, Camarco DP, Shun TY, Lazo JS, Wilson GM, Resnick LO, LaPorte MG, Wipf P, Huryn DM, Grandis JR.

Assay Drug Dev Technol. 2015 Sep;13(7):356-76. doi: 10.1089/adt.2015.663.

12.

AUF1 promotes let-7b loading on Argonaute 2.

Yoon JH, Jo MH, White EJ, De S, Hafner M, Zucconi BE, Abdelmohsen K, Martindale JL, Yang X, Wood WH 3rd, Shin YM, Song JJ, Tuschl T, Becker KG, Wilson GM, Hohng S, Gorospe M.

Genes Dev. 2015 Aug 1;29(15):1599-604. doi: 10.1101/gad.263749.115.

13.

Antiproliferative activities of halogenated pyrrolo[3,2-d]pyrimidines.

Temburnikar KW, Ross CR, Wilson GM, Balzarini J, Cawrse BM, Seley-Radtke KL.

Bioorg Med Chem. 2015 Aug 1;23(15):4354-63. doi: 10.1016/j.bmc.2015.06.025. Epub 2015 Jun 16.

14.

Identification of novel Fgf enhancers and their role in dental evolution.

Tapaltsyan V, Charles C, Hu J, Mindell D, Ahituv N, Wilson GM, Black BL, Viriot L, Klein OD.

Evol Dev. 2016 Jan-Feb;18(1):31-40. doi: 10.1111/ede.12132. Epub 2015 Jun 18.

15.

Association of the Rad9-Rad1-Hus1 checkpoint clamp with MYH DNA glycosylase and DNA.

Hwang BJ, Jin J, Gunther R, Madabushi A, Shi G, Wilson GM, Lu AL.

DNA Repair (Amst). 2015 Jul;31:80-90. doi: 10.1016/j.dnarep.2015.05.004. Epub 2015 May 16.

16.

Mitotic arrest of breast cancer MDA-MB-231 cells by a halogenated thieno[3,2-d]pyrimidine.

Ross CR, Temburnikar KW, Wilson GM, Seley-Radtke KL.

Bioorg Med Chem Lett. 2015 Apr 15;25(8):1715-1717. doi: 10.1016/j.bmcl.2015.02.071. Epub 2015 Mar 7.

17.

A dimer interface mutation in glyceraldehyde 3-phosphate dehydrogenase regulates its binding to AU-rich RNA.

White MR, Khan MM, Deredge D, Ross CR, Quintyn R, Zucconi BE, Wysocki VH, Wintrode PL, Wilson GM, Garcin ED.

J Biol Chem. 2015 Feb 13;290(7):4129. doi: 10.1074/jbc.A114.618165. No abstract available.

18.

Post-transcriptional regulation of transcript abundance by a conserved member of the tristetraprolin family in Candida albicans.

Wells ML, Washington OL, Hicks SN, Nobile CJ, Hartooni N, Wilson GM, Zucconi BE, Huang W, Li L, Fargo DC, Blackshear PJ.

Mol Microbiol. 2015 Mar;95(6):1036-53. doi: 10.1111/mmi.12913. Epub 2015 Jan 30.

19.

A dimer interface mutation in glyceraldehyde-3-phosphate dehydrogenase regulates its binding to AU-rich RNA.

White MR, Khan MM, Deredge D, Ross CR, Quintyn R, Zucconi BE, Wysocki VH, Wintrode PL, Wilson GM, Garcin ED.

J Biol Chem. 2015 Jan 16;290(3):1770-85. doi: 10.1074/jbc.M114.618165. Epub 2014 Dec 1. Erratum in: J Biol Chem. 2015 Feb 13;290(7):4129.

20.

PAR-CLIP analysis uncovers AUF1 impact on target RNA fate and genome integrity.

Yoon JH, De S, Srikantan S, Abdelmohsen K, Grammatikakis I, Kim J, Kim KM, Noh JH, White EJ, Martindale JL, Yang X, Kang MJ, Wood WH 3rd, Noren Hooten N, Evans MK, Becker KG, Tripathi V, Prasanth KV, Wilson GM, Tuschl T, Ingolia NT, Hafner M, Gorospe M.

Nat Commun. 2014 Nov 4;5:5248. doi: 10.1038/ncomms6248.

21.

The Drosophila Tis11 protein and its effects on mRNA expression in flies.

Choi YJ, Lai WS, Fedic R, Stumpo DJ, Huang W, Li L, Perera L, Brewer BY, Wilson GM, Mason JM, Blackshear PJ.

J Biol Chem. 2014 Dec 19;289(51):35042-60. doi: 10.1074/jbc.M114.593491. Epub 2014 Oct 23.

22.

RNase L attenuates mitogen-stimulated gene expression via transcriptional and post-transcriptional mechanisms to limit the proliferative response.

Brennan-Laun SE, Li XL, Ezelle HJ, Venkataraman T, Blackshear PJ, Wilson GM, Hassel BA.

J Biol Chem. 2014 Nov 28;289(48):33629-43. doi: 10.1074/jbc.M114.589556. Epub 2014 Oct 9.

23.

Antiproliferative activities of halogenated thieno[3,2-d]pyrimidines.

Temburnikar KW, Zimmermann SC, Kim NT, Ross CR, Gelbmann C, Salomon CE, Wilson GM, Balzarini J, Seley-Radtke KL.

Bioorg Med Chem. 2014 Apr 1;22(7):2113-22. doi: 10.1016/j.bmc.2014.02.033. Epub 2014 Mar 3.

24.

Improving the analysis of low heritability complex traits for enhanced genetic gain in potato.

Slater AT, Wilson GM, Cogan NO, Forster JW, Hayes BJ.

Theor Appl Genet. 2014 Apr;127(4):809-20. doi: 10.1007/s00122-013-2258-7. Epub 2013 Dec 29.

PMID:
24374468
25.

Scaffold function of long non-coding RNA HOTAIR in protein ubiquitination.

Yoon JH, Abdelmohsen K, Kim J, Yang X, Martindale JL, Tominaga-Yamanaka K, White EJ, Orjalo AV, Rinn JL, Kreft SG, Wilson GM, Gorospe M.

Nat Commun. 2013;4:2939. doi: 10.1038/ncomms3939.

26.

Assembly of functional ribonucleoprotein complexes by AU-rich element RNA-binding protein 1 (AUF1) requires base-dependent and -independent RNA contacts.

Zucconi BE, Wilson GM.

J Biol Chem. 2013 Sep 27;288(39):28034-48. doi: 10.1074/jbc.M113.489559. Epub 2013 Aug 12.

27.

HNO enhances SERCA2a activity and cardiomyocyte function by promoting redox-dependent phospholamban oligomerization.

Sivakumaran V, Stanley BA, Tocchetti CG, Ballin JD, Caceres V, Zhou L, Keceli G, Rainer PP, Lee DI, Huke S, Ziolo MT, Kranias EG, Toscano JP, Wilson GM, O'Rourke B, Kass DA, Mahaney JE, Paolocci N.

Antioxid Redox Signal. 2013 Oct 10;19(11):1185-97. doi: 10.1089/ars.2012.5057.

28.

Protein kinase C δ increases Kruppel-like factor 4 protein, which drives involucrin gene transcription in differentiating keratinocytes.

Chew YC, Adhikary G, Xu W, Wilson GM, Eckert RL.

J Biol Chem. 2013 Jun 14;288(24):17759-68. doi: 10.1074/jbc.M113.477133. Epub 2013 Apr 17.

29.

Diacylglycerol kinase α is a critical signaling node and novel therapeutic target in glioblastoma and other cancers.

Dominguez CL, Floyd DH, Xiao A, Mullins GR, Kefas BA, Xin W, Yacur MN, Abounader R, Lee JK, Wilson GM, Harris TE, Purow BW.

Cancer Discov. 2013 Jul;3(7):782-97. doi: 10.1158/2159-8290.CD-12-0215. Epub 2013 Apr 4.

30.

Combinatorial mRNA binding by AUF1 and Argonaute 2 controls decay of selected target mRNAs.

Wu X, Chesoni S, Rondeau G, Tempesta C, Patel R, Charles S, Daginawala N, Zucconi BE, Kishor A, Xu G, Shi Y, Li ML, Irizarry-Barreto P, Welsh J, Wilson GM, Brewer G.

Nucleic Acids Res. 2013 Feb 1;41(4):2644-58. doi: 10.1093/nar/gks1453. Epub 2013 Jan 8.

31.

Post-transcriptional control of gene expression by AUF1: mechanisms, physiological targets, and regulation.

White EJ, Brewer G, Wilson GM.

Biochim Biophys Acta. 2013 Jun-Jul;1829(6-7):680-8. doi: 10.1016/j.bbagrm.2012.12.002. Epub 2012 Dec 14. Review.

32.

Synthesis and biological evaluation of a selective N- and p/q-type calcium channel agonist.

Liang M, Tarr TB, Bravo-Altamirano K, Valdomir G, Rensch G, Swanson L, DeStefino NR, Mazzarisi CM, Olszewski RA, Wilson GM, Meriney SD, Wipf P.

ACS Med Chem Lett. 2012 Oct 1;3(12):985-90. doi: 10.1021/ml3002083. eCollection 2012 Dec 13.

33.

Role of transcription factor Sp1 and RNA binding protein HuR in the downregulation of Dr+ Escherichia coli receptor protein decay accelerating factor (DAF or CD55) by nitric oxide.

Banadakoppa M, Liebenthal D, Nowak DE, Urvil P, Yallampalli U, Wilson GM, Kishor A, Yallampalli C.

FEBS J. 2013 Feb;280(3):840-54. doi: 10.1111/febs.12073. Epub 2013 Jan 2.

34.

Hsp70 is a novel posttranscriptional regulator of gene expression that binds and stabilizes selected mRNAs containing AU-rich elements.

Kishor A, Tandukar B, Ly YV, Toth EA, Suarez Y, Brewer G, Wilson GM.

Mol Cell Biol. 2013 Jan;33(1):71-84. doi: 10.1128/MCB.01275-12. Epub 2012 Oct 29.

35.

Activation of nuclear factor-kappa B accelerates vascular calcification by inhibiting ankylosis protein homolog expression.

Zhao G, Xu MJ, Zhao MM, Dai XY, Kong W, Wilson GM, Guan Y, Wang CY, Wang X.

Kidney Int. 2012 Jul;82(1):34-44. doi: 10.1038/ki.2012.40. Epub 2012 Mar 21.

36.

Sulforaphane induction of p21(Cip1) cyclin-dependent kinase inhibitor expression requires p53 and Sp1 transcription factors and is p53-dependent.

Chew YC, Adhikary G, Wilson GM, Xu W, Eckert RL.

J Biol Chem. 2012 May 11;287(20):16168-78. doi: 10.1074/jbc.M111.305292. Epub 2012 Mar 15.

37.

Coordinated expression of tristetraprolin post-transcriptionally attenuates mitogenic induction of the oncogenic Ser/Thr kinase Pim-1.

Mahat DB, Brennan-Laun SE, Fialcowitz-White EJ, Kishor A, Ross CR, Pozharskaya T, Rawn JD, Blackshear PJ, Hassel BA, Wilson GM.

PLoS One. 2012;7(3):e33194. doi: 10.1371/journal.pone.0033194. Epub 2012 Mar 8.

38.

Tristetraprolin: roles in cancer and senescence.

Ross CR, Brennan-Laun SE, Wilson GM.

Ageing Res Rev. 2012 Sep;11(4):473-84. doi: 10.1016/j.arr.2012.02.005. Epub 2012 Feb 24. Review.

39.

Statistical testing of input factors in the carbonation of brine impacted fly ash.

Grace MN, Wilson GM, Leslie PF.

J Environ Sci Health A Tox Hazard Subst Environ Eng. 2012;47(2):245-59. doi: 10.1080/10934529.2012.640898.

PMID:
22242877
40.

Direct binding of specific AUF1 isoforms to tandem zinc finger domains of tristetraprolin (TTP) family proteins.

Kedar VP, Zucconi BE, Wilson GM, Blackshear PJ.

J Biol Chem. 2012 Feb 17;287(8):5459-71. doi: 10.1074/jbc.M111.312652. Epub 2011 Dec 27.

41.

Unusual Reactivity of a Potent Platinum-Acridine Hybrid Antitumor Agent.

Graham LA, Wilson GM, West TK, Day CS, Kucera GL, Bierbach U.

ACS Med Chem Lett. 2011 Sep 8;2(9):687-691.

42.

Genetic signature of reproductive manipulation in the phylogeography of the bat fly, Trichobius major.

Lack JB, Nichols RD, Wilson GM, Van Den Bussche RA.

J Hered. 2011 Nov-Dec;102(6):705-18. doi: 10.1093/jhered/esr090. Epub 2011 Sep 2.

PMID:
21890840
43.

Protein kinase C (PKC) delta suppresses keratinocyte proliferation by increasing p21(Cip1) level by a KLF4 transcription factor-dependent mechanism.

Chew YC, Adhikary G, Wilson GM, Reece EA, Eckert RL.

J Biol Chem. 2011 Aug 19;286(33):28772-82. doi: 10.1074/jbc.M110.205245. Epub 2011 Jun 7.

44.

Modulation of neoplastic gene regulatory pathways by the RNA-binding factor AUF1.

Zucconi BE, Wilson GM.

Front Biosci (Landmark Ed). 2011 Jun 1;16:2307-25. Review.

45.

Different modes of interaction by TIAR and HuR with target RNA and DNA.

Kim HS, Wilce MC, Yoga YM, Pendini NR, Gunzburg MJ, Cowieson NP, Wilson GM, Williams BR, Gorospe M, Wilce JA.

Nucleic Acids Res. 2011 Feb;39(3):1117-30. doi: 10.1093/nar/gkq837. Epub 2011 Jan 13.

46.

Unique properties of the Mtr4p-poly(A) complex suggest a role in substrate targeting.

Bernstein J, Ballin JD, Patterson DN, Wilson GM, Toth EA.

Biochemistry. 2010 Dec 14;49(49):10357-70. doi: 10.1021/bi101518x. Epub 2010 Nov 19.

47.

Alternatively expressed domains of AU-rich element RNA-binding protein 1 (AUF1) regulate RNA-binding affinity, RNA-induced protein oligomerization, and the local conformation of bound RNA ligands.

Zucconi BE, Ballin JD, Brewer BY, Ross CR, Huang J, Toth EA, Wilson GM.

J Biol Chem. 2010 Dec 10;285(50):39127-39. doi: 10.1074/jbc.M110.180182. Epub 2010 Oct 6.

48.

miR-519 suppresses tumor growth by reducing HuR levels.

Abdelmohsen K, Kim MM, Srikantan S, Mercken EM, Brennan SE, Wilson GM, Cabo Rd, Gorospe M.

Cell Cycle. 2010 Apr 1;9(7):1354-9. Epub 2010 Apr 1.

49.

Cytosolic protein interactions of the schizophrenia susceptibility gene dysbindin.

Mead CL, Kuzyk MA, Moradian A, Wilson GM, Holt RA, Morin GB.

J Neurochem. 2010 Jun;113(6):1491-503. doi: 10.1111/j.1471-4159.2010.06690.x. Epub 2010 Mar 14.

50.

Contributions of the histidine side chain and the N-terminal alpha-amino group to the binding thermodynamics of oligopeptides to nucleic acids as a function of pH.

Ballin JD, Prevas JP, Ross CR, Toth EA, Wilson GM, Record MT Jr.

Biochemistry. 2010 Mar 9;49(9):2018-30. doi: 10.1021/bi902027z.

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