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Items: 1 to 50 of 809

1.

Lesinurad: Evaluation of Pharmacokinetic and Pharmacodynamic Interactions With Warfarin in Healthy Volunteers.

Shen Z, Lee CA, Wallach K, Valdez S, Wilson DM, Kerr B, Gillen M.

Clin Pharmacol Drug Dev. 2019 Feb 13. doi: 10.1002/cpdd.662. [Epub ahead of print]

PMID:
30758919
2.

Rehabilitation after Hip Fracture for Nursing Home Residents: A Controlled Feasibility Trial.

Beaupre LA, Magaziner JS, Jones CA, Jhangri GS, Johnston DWC, Wilson DM, Majumdar SR.

J Gerontol A Biol Sci Med Sci. 2019 Feb 9. doi: 10.1093/gerona/glz031. [Epub ahead of print]

PMID:
30753303
3.

Effects of Food and Antacids on Pharmacokinetics and Pharmacodynamics of Lesinurad, a Selective Urate Reabsorption Inhibitor.

Shen Z, Lee CA, Valdez S, Yang X, Wilson DM, Flanagan T, Gillen M.

Clin Pharmacol Drug Dev. 2019 Feb 12. doi: 10.1002/cpdd.663. [Epub ahead of print]

PMID:
30748125
4.

Experimental free ligand conformations: a missing link in structure-based drug discovery.

Chiarparin E, Packer MJ, Wilson DM.

Future Med Chem. 2019 Jan;11(2):79-82. doi: 10.4155/fmc-2018-0339. Epub 2019 Jan 16. No abstract available.

5.

Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia.

Tron AE, Belmonte MA, Adam A, Aquila BM, Boise LH, Chiarparin E, Cidado J, Embrey KJ, Gangl E, Gibbons FD, Gregory GP, Hargreaves D, Hendricks JA, Johannes JW, Johnstone RW, Kazmirski SL, Kettle JG, Lamb ML, Matulis SM, Nooka AK, Packer MJ, Peng B, Rawlins PB, Robbins DW, Schuller AG, Su N, Yang W, Ye Q, Zheng X, Secrist JP, Clark EA, Wilson DM, Fawell SE, Hird AW.

Nat Commun. 2018 Dec 17;9(1):5341. doi: 10.1038/s41467-018-07551-w.

6.

Apurinic endonuclease-1 preserves neural genome integrity to maintain homeostasis and thermoregulation and prevent brain tumors.

Dumitrache LC, Shimada M, Downing SM, Kwak YD, Li Y, Illuzzi JL, Russell HR, Wilson DM 3rd, McKinnon PJ.

Proc Natl Acad Sci U S A. 2018 Dec 26;115(52):E12285-E12294. doi: 10.1073/pnas.1809682115. Epub 2018 Dec 11.

PMID:
30538199
7.

Imaging-Based Approach to Extradural Infections of the Spine.

Talbott JF, Shah VN, Uzelac A, Narvid J, Dumont RA, Chin CT, Wilson DM.

Semin Ultrasound CT MR. 2018 Dec;39(6):570-586. doi: 10.1053/j.sult.2018.09.003. Epub 2018 Sep 26. Review. No abstract available.

PMID:
30527522
8.

Regulation of the Intranuclear Distribution of the Cockayne Syndrome Proteins.

Iyama T, Okur MN, Golato T, McNeill DR, Lu H, Hamilton R, Raja A, Bohr VA, Wilson DM 3rd.

Sci Rep. 2018 Nov 30;8(1):17490. doi: 10.1038/s41598-018-36027-6.

9.

Characterization of Stereoselective Metabolism, Inhibitory Effect on Uric Acid Uptake Transporters, and Pharmacokinetics of Lesinurad Atropisomers.

Yang C, Zhou D, Shen Z, Wilson DM, Renner M, Miner JN, Girardet JL, Lee CA.

Drug Metab Dispos. 2019 Feb;47(2):104-113. doi: 10.1124/dmd.118.080549. Epub 2018 Nov 15.

PMID:
30442650
10.

A study of nurse-based Injury Units in Ireland: An emergency care development for consideration worldwide.

Wilson DM, Devkota R.

Int J Health Plann Manage. 2018 Nov 8. doi: 10.1002/hpm.2700. [Epub ahead of print]

PMID:
30408239
11.

Targeting iron metabolism in high-grade glioma with 68Ga-citrate PET/MR.

Behr SC, Villanueva-Meyer JE, Li Y, Wang YH, Wei J, Moroz A, Lee JK, Hsiao JC, Gao KT, Ma W, Cha S, Wilson DM, Seo Y, Nelson SJ, Chang SM, Evans MJ.

JCI Insight. 2018 Nov 2;3(21). pii: 93999. doi: 10.1172/jci.insight.93999. [Epub ahead of print]

12.

Development of a Novel B-Cell Lymphoma 6 (BCL6) PROTAC To Provide Insight into Small Molecule Targeting of BCL6.

McCoull W, Cheung T, Anderson E, Barton P, Burgess J, Byth K, Cao Q, Castaldi MP, Chen H, Chiarparin E, Carbajo RJ, Code E, Cowan S, Davey PR, Ferguson AD, Fillery S, Fuller NO, Gao N, Hargreaves D, Howard MR, Hu J, Kawatkar A, Kemmitt PD, Leo E, Molina DM, O'Connell N, Petteruti P, Rasmusson T, Raubo P, Rawlins PB, Ricchiuto P, Robb GR, Schenone M, Waring MJ, Zinda M, Fawell S, Wilson DM.

ACS Chem Biol. 2018 Nov 16;13(11):3131-3141. doi: 10.1021/acschembio.8b00698. Epub 2018 Oct 17.

PMID:
30335946
13.

Discovery of potent and selective Spleen Tyrosine Kinase inhibitors for the topical treatment of inflammatory skin disease.

Barker MD, Liddle J, Atkinson FL, Wilson DM, Dickson MC, Ramirez-Molina C, Lewis H, Davis RP, Somers DO, Neu M, Jones E, Watson R.

Bioorg Med Chem Lett. 2018 Nov 15;28(21):3458-3462. doi: 10.1016/j.bmcl.2018.09.022. Epub 2018 Sep 18.

PMID:
30249354
14.

Hippocampal Engagement During Recall Depends on Memory Content.

Ross DA, Sadil P, Wilson DM, Cowell RA.

Cereb Cortex. 2018 Aug 28. doi: 10.1093/cercor/bhy182. [Epub ahead of print] No abstract available.

PMID:
30169604
15.

DNA Repair Molecular Beacon assay: a platform for real-time functional analysis of cellular DNA repair capacity.

Li J, Svilar D, McClellan S, Kim JH, Ahn EE, Vens C, Wilson DM 3rd, Sobol RW.

Oncotarget. 2018 Aug 3;9(60):31719-31743. doi: 10.18632/oncotarget.25859. eCollection 2018 Aug 3.

16.

Metabolism and disposition of lesinurad, a uric acid reabsorption inhibitor, in humans.

Shah V, Yang C, Shen Z, Kerr BM, Tieu K, Wilson DM, Hall J, Gillen M, Lee CA.

Xenobiotica. 2018 Sep 12:1-12. doi: 10.1080/00498254.2018.1504257. [Epub ahead of print]

PMID:
30117757
17.

A scoping review of research to assess the frequency, types, and reasons for end-of-life care setting transitions.

Wilson DM, Birch S.

Scand J Public Health. 2018 Aug 13:1403494818785042. doi: 10.1177/1403494818785042. [Epub ahead of print]

PMID:
30102574
18.

Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures.

Lee JS, Adler L, Karathia H, Carmel N, Rabinovich S, Auslander N, Keshet R, Stettner N, Silberman A, Agemy L, Helbling D, Eilam R, Sun Q, Brandis A, Malitsky S, Itkin M, Weiss H, Pinto S, Kalaora S, Levy R, Barnea E, Admon A, Dimmock D, Stern-Ginossar N, Scherz A, Nagamani SCS, Unda M, Wilson DM 3rd, Elhasid R, Carracedo A, Samuels Y, Hannenhalli S, Ruppin E, Erez A.

Cell. 2018 Sep 6;174(6):1559-1570.e22. doi: 10.1016/j.cell.2018.07.019. Epub 2018 Aug 9.

PMID:
30100185
19.

Recognition memory shielded from semantic but not perceptual interference in normal aging.

Wilson DM, Potter KW, Cowell RA.

Neuropsychologia. 2018 Oct;119:448-463. doi: 10.1016/j.neuropsychologia.2018.07.031. Epub 2018 Jul 30.

PMID:
30071206
20.

Sustained Continuous Glucose Monitor Use in Low-Income Youth with Type 1 Diabetes Following Insurance Coverage Supports Expansion of Continuous Glucose Monitor Coverage for All.

Prahalad P, Addala A, Buckingham BA, Wilson DM, Maahs DM.

Diabetes Technol Ther. 2018 Sep;20(9):632-634. doi: 10.1089/dia.2018.0204. Epub 2018 Jul 18. No abstract available.

PMID:
30020810
21.

Low-Dose Anti-Thymocyte Globulin (ATG) Preserves β-Cell Function and Improves HbA1c in New-Onset Type 1 Diabetes.

Haller MJ, Schatz DA, Skyler JS, Krischer JP, Bundy BN, Miller JL, Atkinson MA, Becker DJ, Baidal D, DiMeglio LA, Gitelman SE, Goland R, Gottlieb PA, Herold KC, Marks JB, Moran A, Rodriguez H, Russell W, Wilson DM, Greenbaum CJ; Type 1 Diabetes TrialNet ATG-GCSF Study Group.

Diabetes Care. 2018 Sep;41(9):1917-1925. doi: 10.2337/dc18-0494. Epub 2018 Jul 16.

PMID:
30012675
22.

Effect of Renal Impairment on the Pharmacokinetics and Pharmacodynamics of Verinurad, a Selective Uric Acid Reabsorption Inhibitor.

Smith WB, Hall J, Berg JK, Kazimir M, Yamamoto A, Walker S, Lee CA, Shen Z, Wilson DM, Zhou D, Gillen M, Marbury TC.

Clin Drug Investig. 2018 Aug;38(8):703-713. doi: 10.1007/s40261-018-0652-2.

23.

Use of Hospitals by Older versus Younger Canadians: Myths and Misconceptions.

Wilson DM, Shen Y, Low G.

Can J Aging. 2018 Sep;37(3):309-317. doi: 10.1017/S0714980818000235. Epub 2018 Jun 22.

PMID:
29929565
24.

Pathway-based predictive approaches for non-animal assessment of acute inhalation toxicity.

Clippinger AJ, Allen D, Behrsing H, BéruBé KA, Bolger MB, Casey W, DeLorme M, Gaça M, Gehen SC, Glover K, Hayden P, Hinderliter P, Hotchkiss JA, Iskandar A, Keyser B, Luettich K, Ma-Hock L, Maione AG, Makena P, Melbourne J, Milchak L, Ng SP, Paini A, Page K, Patlewicz G, Prieto P, Raabe H, Reinke EN, Roper C, Rose J, Sharma M, Spoo W, Thorne PS, Wilson DM, Jarabek AM.

Toxicol In Vitro. 2018 Oct;52:131-145. doi: 10.1016/j.tiv.2018.06.009. Epub 2018 Jun 20. Review.

25.

Imaging glutathione depletion in the rat brain using ascorbate-derived hyperpolarized MR and PET probes.

Qin H, Carroll VN, Sriram R, Villanueva-Meyer JE, von Morze C, Wang ZJ, Mutch CA, Keshari KR, Flavell RR, Kurhanewicz J, Wilson DM.

Sci Rep. 2018 May 21;8(1):7928. doi: 10.1038/s41598-018-26296-6.

26.

Measuring glucocorticoid receptor expression in vivo with PET.

Truillet C, Parker MFL, Huynh LT, Wei J, Jami KM, Wang YH, Shen YS, Sriram R, Wilson DM, Kurhanewicz J, Evans MJ.

Oncotarget. 2018 Apr 17;9(29):20399-20408. doi: 10.18632/oncotarget.24911. eCollection 2018 Apr 17.

27.

APE1 deficiency promotes cellular senescence and premature aging features.

Li M, Yang X, Lu X, Dai N, Zhang S, Cheng Y, Zhang L, Yang Y, Liu Y, Yang Z, Wang D, Wilson DM 3rd.

Nucleic Acids Res. 2018 Jun 20;46(11):5664-5677. doi: 10.1093/nar/gky326.

28.

Late-stage deuteration of 13C-enriched substrates for T1 prolongation in hyperpolarized 13C MRI.

Taglang C, Korenchan DE, von Morze C, Yu J, Najac C, Wang S, Blecha JE, Subramaniam S, Bok R, VanBrocklin HF, Vigneron DB, Ronen SM, Sriram R, Kurhanewicz J, Wilson DM, Flavell RR.

Chem Commun (Camb). 2018 May 17;54(41):5233-5236. doi: 10.1039/c8cc02246a.

PMID:
29726563
29.

[11C]Para-Aminobenzoic Acid: A Positron Emission Tomography Tracer Targeting Bacteria-Specific Metabolism.

Mutch CA, Ordonez AA, Qin H, Parker M, Bambarger LE, Villanueva-Meyer JE, Blecha J, Carroll V, Taglang C, Flavell R, Sriram R, VanBrocklin H, Rosenberg O, Ohliger MA, Jain SK, Neumann KD, Wilson DM.

ACS Infect Dis. 2018 Jul 13;4(7):1067-1072. doi: 10.1021/acsinfecdis.8b00061. Epub 2018 May 8.

30.

Clinical Utility of Diffusion-Weighted Imaging in Spinal Infections.

Dumont RA, Keen NN, Bloomer CW, Schwartz BS, Talbott J, Clark AJ, Wilson DM, Chin CT.

Clin Neuroradiol. 2018 Mar 26. doi: 10.1007/s00062-018-0681-5. [Epub ahead of print]

PMID:
29582111
31.

Organic synthesis provides opportunities to transform drug discovery.

Blakemore DC, Castro L, Churcher I, Rees DC, Thomas AW, Wilson DM, Wood A.

Nat Chem. 2018 Apr;10(4):383-394. doi: 10.1038/s41557-018-0021-z. Epub 2018 Mar 22. Review.

PMID:
29568051
32.

Parents' Executive Functioning and Involvement in Their Child's Education: An Integrated Literature Review.

Wilson DM, Gross D.

J Sch Health. 2018 Apr;88(4):322-329. doi: 10.1111/josh.12612.

33.

Metabolism and Disposition of Verinurad, a Uric Acid Reabsorption Inhibitor, in Humans.

Lee CA, Yang C, Shah V, Shen Z, Wilson DM, Ostertag TM, Girardet JL, Hall J, Gillen M.

Drug Metab Dispos. 2018 May;46(5):532-541. doi: 10.1124/dmd.117.078220. Epub 2018 Feb 28.

PMID:
29490903
34.

Nurse and midwifery prescribing in Ireland: A scope-of-practice development for worldwide consideration.

Wilson DM, Murphy J, Nam MA, Fahy A, Tella S.

Nurs Health Sci. 2018 Jun;20(2):264-270. doi: 10.1111/nhs.12408. Epub 2018 Jan 29.

PMID:
29377551
35.

Place of death for people with HIV: a population-level comparison of eleven countries across three continents using death certificate data.

Harding R, Marchetti S, Onwuteaka-Philipsen BD, Wilson DM, Ruiz-Ramos M, Cardenas-Turanzas M, Rhee Y, Morin L, Hunt K, Teno J, Hakanson C, Houttekier D, Deliens L, Cohen J.

BMC Infect Dis. 2018 Jan 25;18(1):55. doi: 10.1186/s12879-018-2951-x.

36.

Pharmacokinetics, safety, and patient acceptability of subcutaneous versus intramuscular testosterone injection for gender-affirming therapy: A pilot study.

Wilson DM, Kiang TKL, Ensom MHH.

Am J Health Syst Pharm. 2018 Mar 15;75(6):351-358. doi: 10.2146/ajhp170160. Epub 2018 Jan 24.

PMID:
29367424
37.

Direct assessment of renal mitochondrial redox state using hyperpolarized 13 C-acetoacetate.

von Morze C, Ohliger MA, Marco-Rius I, Wilson DM, Flavell RR, Pearce D, Vigneron DB, Kurhanewicz J, Wang ZJ.

Magn Reson Med. 2018 Apr;79(4):1862-1869. doi: 10.1002/mrm.27054. Epub 2018 Jan 3.

PMID:
29314217
38.

Alternative approaches for acute inhalation toxicity testing to address global regulatory and non-regulatory data requirements: An international workshop report.

Clippinger AJ, Allen D, Jarabek AM, Corvaro M, Gaça M, Gehen S, Hotchkiss JA, Patlewicz G, Melbourne J, Hinderliter P, Yoon M, Huh D, Lowit A, Buckley B, Bartels M, BéruBé K, Wilson DM, Indans I, Vinken M.

Toxicol In Vitro. 2018 Apr;48:53-70. doi: 10.1016/j.tiv.2017.12.011. Epub 2017 Dec 22.

39.

50 Years Ago in The Journal of Pediatrics: Familial Holoprosencephaly with Endocrine Dysgenesis.

Chang M, Wilson DM, Maahs DM.

J Pediatr. 2018 Jan;192:98. doi: 10.1016/j.jpeds.2017.07.027. No abstract available.

PMID:
29246365
40.

Correction to The Discovery of Novel Antimalarial Aminoxadiazoles as a Promising Nonendoperoxide Scaffold.

Sandoval E, Lafuente-Monasterio MJ, Almela MJ, Castañeda P, Jiménez Díaz MB, Martínez-Martínez MS, Vidal J, Angulo-Barturen Í, Bamborough P, Burrows J, Cammack N, Chaparro MJ, Coterón JM, de Cozar C, Crespo B, Díaz B, Drewes G, Fernández E, Ferrer-Bazaga S, Fraile MT, Gamo FJ, Ghidelli-Disse S, Gómez R, Haselden J, Huss S, León ML, de Mercado J, Macdonald SJF, Martín Hernando JI, Prats S, Puente M, Rodríguez A, de la Rosa JC, Rueda L, Selenski C, Willis P, Wilson DM, Witty M, Calderón F.

J Med Chem. 2017 Dec 14;60(23):9911. doi: 10.1021/acs.jmedchem.7b01491. Epub 2017 Nov 22. No abstract available.

PMID:
29164877
41.

Predictive hyperglycemia and hypoglycemia minimization: In-home double-blind randomized controlled evaluation in children and young adolescents.

Forlenza GP, Raghinaru D, Cameron F, Wayne Bequette B, Peter Chase H, Paul Wadwa R, Maahs DM, Jost E, Ly TT, Wilson DM, Norlander L, Ekhlaspour L, Min H, Clinton P, Njeru N, Lum JW, Kollman C, Beck RW, Buckingham BA; In-Home Closed-Loop (IHCL) Study Group.

Pediatr Diabetes. 2018 May;19(3):420-428. doi: 10.1111/pedi.12603. Epub 2017 Nov 20.

42.

Moving from place to place in the last year of life: A qualitative study identifying care setting transition issues and solutions in Ontario.

Wilson DM, Birch S.

Health Soc Care Community. 2018 Mar;26(2):232-239. doi: 10.1111/hsc.12513. Epub 2017 Nov 6.

PMID:
29108131
43.

Development of a Cell-Based Assay for Measuring Base Excision Repair Responses.

Golato T, Brenerman B, McNeill DR, Li J, Sobol RW, Wilson DM 3rd.

Sci Rep. 2017 Oct 11;7(1):13007. doi: 10.1038/s41598-017-12963-7.

44.

Bereavement grief: A population-based foundational evidence study.

Wilson DM, Cohen J, MacLeod R, Houttekier D.

Death Stud. 2018 Aug;42(7):463-469. doi: 10.1080/07481187.2017.1382609. Epub 2018 Jan 9.

PMID:
28985143
45.

Features and Outcomes of Methamphetamine-associated Pulmonary Arterial Hypertension.

Zamanian RT, Hedlin H, Greuenwald P, Wilson DM, Segal JI, Jorden M, Kudelko K, Liu J, Hsi A, Rupp A, Sweatt AJ, Tuder R, Berry GJ, Rabinovitch M, Doyle RL, de Jesus Perez V, Kawut SM.

Am J Respir Crit Care Med. 2018 Mar 15;197(6):788-800. doi: 10.1164/rccm.201705-0943OC.

PMID:
28934596
46.

Systematic analysis of DNA crosslink repair pathways during development and aging in Caenorhabditis elegans.

Wilson DM 3rd, Rieckher M, Williams AB, Schumacher B.

Nucleic Acids Res. 2017 Sep 19;45(16):9467-9480. doi: 10.1093/nar/gkx660.

47.

The Role of PET/MR Imaging in Precision Medicine.

Huo E, Wilson DM, Eisenmenger L, Hope TA.

PET Clin. 2017 Oct;12(4):489-501. doi: 10.1016/j.cpet.2017.05.006. Epub 2017 Jul 28. Review.

PMID:
28867118
48.

Dysglycemia and Index60 as Prediagnostic End Points for Type 1 Diabetes Prevention Trials.

Nathan BM, Boulware D, Geyer S, Atkinson MA, Colman P, Goland R, Russell W, Wentworth JM, Wilson DM, Evans-Molina C, Wherrett D, Skyler JS, Moran A, Sosenko JM; Type 1 Diabetes TrialNet and Diabetes Prevention Trial–Type 1 Study Groups.

Diabetes Care. 2017 Nov;40(11):1494-1499. doi: 10.2337/dc17-0916. Epub 2017 Aug 31.

49.

Exploring Metabolism In Vivo Using Endogenous 11C Metabolic Tracers.

Neumann K, Flavell R, Wilson DM.

Semin Nucl Med. 2017 Sep;47(5):461-473. doi: 10.1053/j.semnuclmed.2017.05.003. Epub 2017 Jul 11. Review.

50.

The Discovery of Novel Antimalarial Aminoxadiazoles as a Promising Nonendoperoxide Scaffold.

Sandoval E, Lafuente-Monasterio MJ, Almela MJ, Castañeda P, Jiménez Díaz MB, Martínez-Martínez MS, Vidal J, Angulo-Barturen Í, Bamborough P, Burrows J, Cammack N, Chaparro MJ, Coterón JM, de Cozar C, Crespo B, Díaz B, Drewes G, Fernández E, Ferrer-Bazaga S, Fraile MT, Gamo FJ, Ghidelli-Disse S, Gómez R, Haselden J, Huss S, León ML, de Mercado J, Macdonald SJF, Martín Hernando JI, Prats S, Puente M, Rodríguez A, de la Rosa JC, Rueda L, Selenski C, Willis P, Wilson DM, Witty M, Calderón F.

J Med Chem. 2017 Aug 24;60(16):6880-6896. doi: 10.1021/acs.jmedchem.6b01441. Epub 2017 Aug 14. Erratum in: J Med Chem. 2017 Dec 14;60(23):9911.

PMID:
28806082

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