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Interleukin 1 receptor antagonist (IL1RN) gene variants predict radiographic severity of knee osteoarthritis and risk of incident disease.

Attur M, Zhou H, Samuels J, Krasnokutsky S, Yau M, Scher JU, Doherty M, Wilson AG, Bencardino J, Hochberg M, Jordan JM, Mitchell B, Kraus VB, Abramson SB.

Ann Rheum Dis. 2020 Mar;79(3):400-407. doi: 10.1136/annrheumdis-2019-216055. Epub 2019 Dec 18.


Association of the Rheumatoid Arthritis Severity Variant rs26232 with the Invasive Activity of Synovial Fibroblasts.

Dorris ER, Linehan E, Trenkmann M, Veale DJ, Fearon U, Wilson AG.

Cells. 2019 Oct 22;8(10). pii: E1300. doi: 10.3390/cells8101300.


Can machine learning predict responses to TNF inhibitors?

Nair N, Wilson AG.

Nat Rev Rheumatol. 2019 Dec;15(12):702-704. doi: 10.1038/s41584-019-0320-9. No abstract available.


Differential DNA methylation correlates with response to methotrexate in rheumatoid arthritis.

Nair N, Plant D, Verstappen SM, Isaacs JD, Morgan AW, Hyrich KL, Barton A, Wilson AG.

Rheumatology (Oxford). 2019 Oct 10. pii: kez411. doi: 10.1093/rheumatology/kez411. [Epub ahead of print]


Low-Voltage Flow-Through Electroporation Membrane and Method.

Experton J, Wilson AG, Martin CR.

Methods Mol Biol. 2020;2050:43-55. doi: 10.1007/978-1-4939-9740-4_5.


Patient and public involvement in biomedical research: training is not a substitute for relationship building.

Wilson AG, Sherwin J, Dorris ER.

Ann Rheum Dis. 2019 Nov;78(11):1607-1608. doi: 10.1136/annrheumdis-2019-215595. Epub 2019 Jul 12. No abstract available.


Facilitating public and patient involvement in basic and preclinical health research.

Maccarthy J, Guerin S, Wilson AG, Dorris ER.

PLoS One. 2019 May 14;14(5):e0216600. doi: 10.1371/journal.pone.0216600. eCollection 2019.


Association of response to TNF inhibitors in rheumatoid arthritis with quantitative trait loci for CD40 and CD39.

Spiliopoulou A, Colombo M, Plant D, Nair N, Cui J, Coenen MJ, Ikari K, Yamanaka H, Saevarsdottir S, Padyukov L, Bridges SL Jr, Kimberly RP, Okada Y, van Riel PLC, Wolbink G, van der Horst-Bruinsma IE, de Vries N, Tak PP, Ohmura K, Canhão H, Guchelaar HJ, Huizinga TW, Criswell LA, Raychaudhuri S, Weinblatt ME, Wilson AG, Mariette X, Isaacs JD, Morgan AW, Pitzalis C, Barton A, McKeigue P.

Ann Rheum Dis. 2019 Aug;78(8):1055-1061. doi: 10.1136/annrheumdis-2018-214877. Epub 2019 Apr 29.


The Autoimmune Susceptibility Gene C5orf30 Regulates Macrophage-Mediated Resolution of Inflammation.

Dorris ER, Tazzyman SJ, Moylett J, Ramamoorthi N, Hackney J, Townsend M, Muthana M, Lewis MJ, Pitzalis C, Wilson AG.

J Immunol. 2019 Feb 15;202(4):1069-1078. doi: 10.4049/jimmunol.1801155. Epub 2019 Jan 18.


Genome-wide association study of response to tumour necrosis factor inhibitor therapy in rheumatoid arthritis.

Massey J, Plant D, Hyrich K, Morgan AW, Wilson AG, Spiliopoulou A, Colombo M, McKeigue P, Isaacs J, Cordell H, Pitzalis C, Barton A; BRAGGSS, MATURA Consortium.

Pharmacogenomics J. 2018 Sep;18(5):657-664. doi: 10.1038/s41397-018-0040-6. Epub 2018 Aug 31.


Clinical signs, treatment, and prognostic factors for dogs with histoplasmosis.

Wilson AG, KuKanich KS, Hanzlicek AS, Payton ME.

J Am Vet Med Assoc. 2018 Jan 15;252(2):201-209. doi: 10.2460/javma.252.2.201.


Serum N-propeptide of collagen IIA (PIIANP) as a marker of radiographic osteoarthritis burden.

Daghestani HN, Jordan JM, Renner JB, Doherty M, Wilson AG, Kraus VB.

PLoS One. 2017 Dec 29;12(12):e0190251. doi: 10.1371/journal.pone.0190251. eCollection 2017.


Open Surgical Implantation of a Viable Intact Cryopreserved Human Placental Membrane for the Treatment of Recalcitrant Plantar Fasciitis: Case Report With Greater than 2-Year Follow-Up Duration.

Sun XP, Wilson AG, Michael GM.

J Foot Ankle Surg. 2018 May - Jun;57(3):583-586. doi: 10.1053/j.jfas.2017.09.007. Epub 2017 Dec 20. Review.


Design and Validation of Patient-Centered Communication Tools (PaCT) to Measure Students' Communication Skills.

Grice GR, Gattas NM, Prosser T, Voorhees M, Kebodeaux C, Tiemeier A, Berry TM, Wilson AG, Mann J, Juang P.

Am J Pharm Educ. 2017 Oct;81(8):5927. doi: 10.5688/ajpe5927.


Autoimmune-autoinflammatory rheumatoid arthritis overlaps: a rare but potentially important subgroup of diseases.

Savic S, Mistry A, Wilson AG, Barcenas-Morales G, Doffinger R, Emery P, McGonagle D.

RMD Open. 2017 Nov 1;3(2):e000550. doi: 10.1136/rmdopen-2017-000550. eCollection 2017.


Tobacco's minor alkaloids: Effects on place conditioning and nucleus accumbens dopamine release in adult and adolescent rats.

Marusich JA, Darna M, Wilson AG, Denehy ED, Ebben A, Deaciuc AG, Dwoskin LP, Bardo MT, Lefever TW, Wiley JL, Reissig CJ, Jackson KJ.

Eur J Pharmacol. 2017 Nov 5;814:196-206. doi: 10.1016/j.ejphar.2017.08.029. Epub 2017 Aug 26.


DNA methylation as a marker of response in rheumatoid arthritis.

Nair N, Wilson AG, Barton A.

Pharmacogenomics. 2017 Sep;18(14):1323-1332. doi: 10.2217/pgs-2016-0195. Epub 2017 Aug 24. Review.


The role of genetic analysis for predicting outcome of rheumatoid arthritis.

Chaudhry M, Wilson AG.

Expert Rev Mol Diagn. 2017 Sep;17(9):809-814. doi: 10.1080/14737159.2017.1355732. Epub 2017 Jul 19. Review.


Low-Voltage Flow-Through Electroporation in Gold-Microtube Membranes.

Experton J, Wilson AG, Martin CR.

Anal Chem. 2016 Dec 20;88(24):12445-12452. doi: 10.1021/acs.analchem.6b03820. Epub 2016 Dec 6.


The predictive value of serum S100A9 and response to etanercept is not confirmed in a large UK rheumatoid arthritis cohort.

Smith SL, Plant D, Eyre S, Hyrich K, Morgan AW, Wilson AG, Isaacs JD, Barton A.

Rheumatology (Oxford). 2017 Jun 1;56(6):1019-1024. doi: 10.1093/rheumatology/kew387.


Discovery of LX2761, a Sodium-Dependent Glucose Cotransporter 1 (SGLT1) Inhibitor Restricted to the Intestinal Lumen, for the Treatment of Diabetes.

Goodwin NC, Ding ZM, Harrison BA, Strobel ED, Harris AL, Smith M, Thompson AY, Xiong W, Mseeh F, Bruce DJ, Diaz D, Gopinathan S, Li L, O'Neill E, Thiel M, Wilson AG, Carson KG, Powell DR, Rawlins DB.

J Med Chem. 2017 Jan 26;60(2):710-721. doi: 10.1021/acs.jmedchem.6b01541. Epub 2017 Jan 17.


Learning Scalable Deep Kernels with Recurrent Structure.

Al-Shedivat M, Wilson AG, Saatchi Y, Hu Z, Xing EP.

J Mach Learn Res. 2017 Jan;18(1):2850-2886.


Suboptimal choice in rats: Incentive salience attribution promotes maladaptive decision-making.

Chow JJ, Smith AP, Wilson AG, Zentall TR, Beckmann JS.

Behav Brain Res. 2017 Mar 1;320:244-254. doi: 10.1016/j.bbr.2016.12.013. Epub 2016 Dec 16.


Incorporating Concomitant Medications into Genome-Wide Analyses for the Study of Complex Disease and Drug Response.

Graham HT, Rotroff DM, Marvel SW, Buse JB, Havener TM, Wilson AG, Wagner MJ, Motsinger-Reif AA; ACCORD/ACCORDion Investigators.

Front Genet. 2016 Aug 17;7:138. eCollection 2016.


Naturalistic assessment of demand for cigarettes, snus, and nicotine gum.

Stein JS, Wilson AG, Koffarnus MN, Judd MC, Bickel WK.

Psychopharmacology (Berl). 2017 Jan;234(2):245-254. doi: 10.1007/s00213-016-4455-y. Epub 2016 Oct 11.


Stuck in Time: Negative Income Shock Constricts the Temporal Window of Valuation Spanning the Future and the Past.

Bickel WK, Wilson AG, Chen C, Koffarnus MN, Franck CT.

PLoS One. 2016 Sep 15;11(9):e0163051. doi: 10.1371/journal.pone.0163051. eCollection 2016.


Detection of anti-drug antibodies using a bridging ELISA compared with radioimmunoassay in adalimumab-treated rheumatoid arthritis patients with random drug levels.

Jani M, Isaacs JD, Morgan AW, Wilson AG, Plant D, Hyrich KL, Chinoy H, Barton A.

Rheumatology (Oxford). 2016 Nov;55(11):2050-2055. Epub 2016 Aug 25.


Unstuck in time: episodic future thinking reduces delay discounting and cigarette smoking.

Stein JS, Wilson AG, Koffarnus MN, Daniel TO, Epstein LH, Bickel WK.

Psychopharmacology (Berl). 2016 Oct;233(21-22):3771-3778. Epub 2016 Aug 23.


Use of Bayesian Inference in Crystallographic Structure Refinement via Full Diffraction Profile Analysis.

Fancher CM, Han Z, Levin I, Page K, Reich BJ, Smith RC, Wilson AG, Jones JL.

Sci Rep. 2016 Aug 23;6:31625. doi: 10.1038/srep31625.


High frequency of antidrug antibodies and association of random drug levels with efficacy in certolizumab pegol-treated patients with rheumatoid arthritis: results from the BRAGGSS cohort.

Jani M, Isaacs JD, Morgan AW, Wilson AG, Plant D, Hyrich KL, Chinoy H, Barton A; BRAGGSS.

Ann Rheum Dis. 2017 Jan;76(1):208-213. doi: 10.1136/annrheumdis-2015-208849. Epub 2016 May 31.


Previously reported PDE3A-SLCO1C1 genetic variant does not correlate with anti-TNF response in a large UK rheumatoid arthritis cohort.

Smith SL, Plant D, Lee XH, Massey J, Hyrich K, Morgan AW, Wilson AG, Isaacs J, Barton A.

Pharmacogenomics. 2016 May;17(7):715-20. doi: 10.2217/pgs.16.16. Epub 2016 May 16.


Stimulation of cortical bone formation with thienopyrimidine based inhibitors of Notum Pectinacetylesterase.

Tarver JE Jr, Pabba PK, Barbosa J, Han Q, Gardyan MW, Brommage R, Thompson AY, Schmidt JM, Wilson AGE, He W, Lombardo VK, Carson KG.

Bioorg Med Chem Lett. 2016 Mar 15;26(6):1525-1528. doi: 10.1016/j.bmcl.2016.02.021. Epub 2016 Feb 10.


4H-Thieno[3,2-c]chromene based inhibitors of Notum Pectinacetylesterase.

Han Q, Pabba PK, Barbosa J, Mabon R, Healy JP, Gardyan MW, Terranova KM, Brommage R, Thompson AY, Schmidt JM, Wilson AG, Xu X, Tarver JE Jr, Carson KG.

Bioorg Med Chem Lett. 2016 Feb 15;26(4):1184-7. doi: 10.1016/j.bmcl.2016.01.038. Epub 2016 Jan 18.


Differential Methylation as a Biomarker of Response to Etanercept in Patients With Rheumatoid Arthritis.

Plant D, Webster A, Nair N, Oliver J, Smith SL, Eyre S, Hyrich KL, Wilson AG, Morgan AW, Isaacs JD, Worthington J, Barton A.

Arthritis Rheumatol. 2016 Jun;68(6):1353-60. doi: 10.1002/art.39590. Epub 2016 Apr 21.


The relative value of two options for pigeons depends on their context.

Pinto C, Fortes I, Wilson AG, Zentall TR.

J Exp Anal Behav. 2016 Jan;105(1):176-83. doi: 10.1002/jeab.187.


Investigating CD11c expression as a potential genomic biomarker of response to TNF inhibitor biologics in whole blood rheumatoid arthritis samples.

Smith SL, Eyre S, Yarwood A, Hyrich K, Morgan AW, Wilson AG, Isaacs J; Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate 6, Plant D, Barton A.

Arthritis Res Ther. 2015 Dec 14;17:359. doi: 10.1186/s13075-015-0868-y.


Genome-wide association meta-analyses to identify common genetic variants associated with hallux valgus in Caucasian and African Americans.

Hsu YH, Liu Y, Hannan MT, Maixner W, Smith SB, Diatchenko L, Golightly YM, Menz HB, Kraus VB, Doherty M, Wilson AG, Jordan JM.

J Med Genet. 2015 Nov;52(11):762-9. doi: 10.1136/jmedgenet-2015-103142. Epub 2015 Sep 2.


C5orf30 is a negative regulator of tissue damage in rheumatoid arthritis.

Muthana M, Hawtree S, Wilshaw A, Linehan E, Roberts H, Khetan S, Adeleke G, Wright F, Akil M, Fearon U, Veale D, Ciani B, Wilson AG.

Proc Natl Acad Sci U S A. 2015 Sep 15;112(37):11618-23. doi: 10.1073/pnas.1501947112. Epub 2015 Aug 27.


Clinical utility of random anti-tumour necrosis factor drug testing and measurement of anti-drug antibodies on long-term treatment response in rheumatoid arthritis.

Jani M, Chinoy H, Warren RB, Griffiths CE, Plant D, Morgan AW, Wilson AG, Hyrich KL, Isaacs J, Barton A.

Lancet. 2015 Feb 26;385 Suppl 1:S48. doi: 10.1016/S0140-6736(15)60363-4.


Genetic Divergence of an Avian Endemic on the Californian Channel Islands.

Wilson AG, Chan Y, Taylor SS, Arcese P.

PLoS One. 2015 Aug 26;10(8):e0134471. doi: 10.1371/journal.pone.0134471. eCollection 2015.


Behavioral Economics of Cigarette Purchase Tasks: Within-Subject Comparison of Real, Potentially Real, and Hypothetical Cigarettes.

Wilson AG, Franck CT, Koffarnus MN, Bickel WK.

Nicotine Tob Res. 2016 May;18(5):524-30. doi: 10.1093/ntr/ntv154. Epub 2015 Jul 17.


Histone deacetylase 1 regulates tissue destruction in rheumatoid arthritis.

Hawtree S, Muthana M, Wilkinson JM, Akil M, Wilson AG.

Hum Mol Genet. 2015 Oct 1;24(19):5367-77. doi: 10.1093/hmg/ddv258. Epub 2015 Jul 7.


Clinical utility of random anti-tumor necrosis factor drug-level testing and measurement of antidrug antibodies on the long-term treatment response in rheumatoid arthritis.

Jani M, Chinoy H, Warren RB, Griffiths CE, Plant D, Fu B, Morgan AW, Wilson AG, Isaacs JD, Hyrich K, Barton A; Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate Collaborators.

Arthritis Rheumatol. 2015 May;67(8):2011-9. doi: 10.1002/art.39169. Erratum in: Arthritis Rheumatol. 2015 Nov;67(11):3096.


Association of HLA-DRB1 haplotypes with rheumatoid arthritis severity, mortality, and treatment response.

Viatte S, Plant D, Han B, Fu B, Yarwood A, Thomson W, Symmons DP, Worthington J, Young A, Hyrich KL, Morgan AW, Wilson AG, Isaacs JD, Raychaudhuri S, Barton A.

JAMA. 2015 Apr 28;313(16):1645-56. doi: 10.1001/jama.2015.3435.


Rheumatoid arthritis response to treatment across IgG1 allotype - anti-TNF incompatibility: a case-only study.

Montes A, Perez-Pampin E, Navarro-Sarabia F, Moreira V, de la Serna AR, Magallares B, Vasilopoulos Y, Sarafidou T, Fernández-Nebro A, Ordóñez Mdel C, Narváez J, Cañete JD, Marquez A, Pascual-Salcedo D, Joven B, Carreira P, Moreno-Ramos MJ, Caliz R, Ferrer MA, Garcia-Portales R, Blanco FJ, Magro C, Raya E, Valor L, Alegre-Sancho JJ, Balsa A, Martin J, Plant D, Isaacs J, Morgan AW, Barton A, Wilson AG; Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate (BRAGGSS), Gómez-Reino JJ, Gonzalez A.

Arthritis Res Ther. 2015 Mar 18;17:63. doi: 10.1186/s13075-015-0571-z.


The influence of multiple temporal memories in the peak-interval procedure.

Wilson AG, Matell MS, Crystal JD.

Learn Behav. 2015 Jun;43(2):153-62. doi: 10.3758/s13420-015-0169-y.


Discovery and Development of LX7101, a Dual LIM-Kinase and ROCK Inhibitor for the Treatment of Glaucoma.

Harrison BA, Almstead ZY, Burgoon H, Gardyan M, Goodwin NC, Healy J, Liu Y, Mabon R, Marinelli B, Samala L, Zhang Y, Stouch TR, Whitlock NA, Gopinathan S, McKnight B, Wang S, Patel N, Wilson AG, Hamman BD, Rice DS, Rawlins DB.

ACS Med Chem Lett. 2014 Nov 24;6(1):84-8. doi: 10.1021/ml500367g. eCollection 2015 Jan 8.


Impact of inadequate adherence on response to subcutaneously administered anti-tumour necrosis factor drugs: results from the Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate cohort.

Bluett J, Morgan C, Thurston L, Plant D, Hyrich KL, Morgan AW, Wilson AG, Isaacs JD, Cordingley L, Barton A; BRAGGSS.

Rheumatology (Oxford). 2015 Mar;54(3):494-9. doi: 10.1093/rheumatology/keu358. Epub 2014 Sep 10.

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