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Items: 17


Novel ACE2-Fc chimeric fusion provides long-lasting hypertension control and organ protection in mouse models of systemic renin angiotensin system activation.

Liu P, Wysocki J, Souma T, Ye M, Ramirez V, Zhou B, Wilsbacher LD, Quaggin SE, Batlle D, Jin J.

Kidney Int. 2018 Jul;94(1):114-125. doi: 10.1016/j.kint.2018.01.029. Epub 2018 Apr 22.


A novel acetyltransferase p300 inhibitor ameliorates hypertension-associated cardio-renal fibrosis.

Rai R, Verma SK, Kim D, Ramirez V, Lux E, Li C, Sahoo S, Wilsbacher LD, Vaughan DE, Quaggin SE, Ghosh AK.

Epigenetics. 2017;12(11):1004-1013. doi: 10.1080/15592294.2017.1370173. Epub 2017 Dec 6.


Experimental Modeling Supports a Role for MyBP-HL as a Novel Myofilament Component in Arrhythmia and Dilated Cardiomyopathy.

Barefield DY, Puckelwartz MJ, Kim EY, Wilsbacher LD, Vo AH, Waters EA, Earley JU, Hadhazy M, Dellefave-Castillo L, Pesce LL, McNally EM.

Circulation. 2017 Oct 17;136(16):1477-1491. doi: 10.1161/CIRCULATIONAHA.117.028585. Epub 2017 Aug 4.


Sirtuin 2 regulates cellular iron homeostasis via deacetylation of transcription factor NRF2.

Yang X, Park SH, Chang HC, Shapiro JS, Vassilopoulos A, Sawicki KT, Chen C, Shang M, Burridge PW, Epting CL, Wilsbacher LD, Jenkitkasemwong S, Knutson M, Gius D, Ardehali H.

J Clin Invest. 2017 Apr 3;127(4):1505-1516. doi: 10.1172/JCI88574. Epub 2017 Mar 13.


A small molecule inhibitor of PAI-1 protects against doxorubicin-induced cellular senescence.

Ghosh AK, Rai R, Park KE, Eren M, Miyata T, Wilsbacher LD, Vaughan DE.

Oncotarget. 2016 Nov 8;7(45):72443-72457. doi: 10.18632/oncotarget.12494.


Sphingosine 1-phosphate receptor-1 in cardiomyocytes is required for normal cardiac development.

Clay H, Wilsbacher LD, Wilson SJ, Duong DN, McDonald M, Lam I, Park KE, Chun J, Coughlin SR.

Dev Biol. 2016 Oct 1;418(1):157-165. doi: 10.1016/j.ydbio.2016.06.024. Epub 2016 Jun 19.


An internal promoter underlies the difference in disease severity between N- and C-terminal truncation mutations of Titin in zebrafish.

Zou J, Tran D, Baalbaki M, Tang LF, Poon A, Pelonero A, Titus EW, Yuan C, Shi C, Patchava S, Halper E, Garg J, Movsesyan I, Yin C, Wu R, Wilsbacher LD, Liu J, Hager RL, Coughlin SR, Jinek M, Pullinger CR, Kane JP, Hart DO, Kwok PY, Deo RC.

Elife. 2015 Oct 16;4:e09406. doi: 10.7554/eLife.09406.


Analysis of cardiomyocyte development using immunofluorescence in embryonic mouse heart.

Wilsbacher LD, Coughlin SR.

J Vis Exp. 2015 Mar 26;(97). doi: 10.3791/52644.


Dissecting the functions of the mammalian clock protein BMAL1 by tissue-specific rescue in mice.

McDearmon EL, Patel KN, Ko CH, Walisser JA, Schook AC, Chong JL, Wilsbacher LD, Song EJ, Hong HK, Bradfield CA, Takahashi JS.

Science. 2006 Nov 24;314(5803):1304-8.


Photic and circadian expression of luciferase in mPeriod1-luc transgenic mice invivo.

Wilsbacher LD, Yamazaki S, Herzog ED, Song EJ, Radcliffe LA, Abe M, Block G, Spitznagel E, Menaker M, Takahashi JS.

Proc Natl Acad Sci U S A. 2002 Jan 8;99(1):489-94. Epub 2001 Dec 18.


Mop3 is an essential component of the master circadian pacemaker in mammals.

Bunger MK, Wilsbacher LD, Moran SM, Clendenin C, Radcliffe LA, Hogenesch JB, Simon MC, Takahashi JS, Bradfield CA.

Cell. 2000 Dec 22;103(7):1009-17.


The mouse Clock locus: sequence and comparative analysis of 204 kb from mouse chromosome 5.

Wilsbacher LD, Sangoram AM, Antoch MP, Takahashi JS.

Genome Res. 2000 Dec;10(12):1928-40.


Circadian rhythms: molecular basis of the clock.

Wilsbacher LD, Takahashi JS.

Curr Opin Genet Dev. 1998 Oct;8(5):595-602. Review.


Role of the CLOCK protein in the mammalian circadian mechanism.

Gekakis N, Staknis D, Nguyen HB, Davis FC, Wilsbacher LD, King DP, Takahashi JS, Weitz CJ.

Science. 1998 Jun 5;280(5369):1564-9.


Adrenocorticotropin induction of stress-activated protein kinase in the adrenal cortex in vivo.

Watanabe G, Pena P, Albanese C, Wilsbacher LD, Young JB, Pestell RG.

J Biol Chem. 1997 Aug 8;272(32):20063-9.


Functional identification of the mouse circadian Clock gene by transgenic BAC rescue.

Antoch MP, Song EJ, Chang AM, Vitaterna MH, Zhao Y, Wilsbacher LD, Sangoram AM, King DP, Pinto LH, Takahashi JS.

Cell. 1997 May 16;89(4):655-67.


Positional cloning of the mouse circadian clock gene.

King DP, Zhao Y, Sangoram AM, Wilsbacher LD, Tanaka M, Antoch MP, Steeves TD, Vitaterna MH, Kornhauser JM, Lowrey PL, Turek FW, Takahashi JS.

Cell. 1997 May 16;89(4):641-53.

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