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Items: 8


The expression of GPIHBP1, an endothelial cell binding site for lipoprotein lipase and chylomicrons, is induced by peroxisome proliferator-activated receptor-gamma.

Davies BS, Waki H, Beigneux AP, Farber E, Weinstein MM, Wilpitz DC, Tai LJ, Evans RM, Fong LG, Tontonoz P, Young SG.

Mol Endocrinol. 2008 Nov;22(11):2496-504. doi: 10.1210/me.2008-0146. Epub 2008 Sep 11. Erratum in: Mol Endocrinol. 2008 Dec;22(12):2766.


Ligand activation of LXR beta reverses atherosclerosis and cellular cholesterol overload in mice lacking LXR alpha and apoE.

Bradley MN, Hong C, Chen M, Joseph SB, Wilpitz DC, Wang X, Lusis AJ, Collins A, Hseuh WA, Collins JL, Tangirala RK, Tontonoz P.

J Clin Invest. 2007 Aug;117(8):2337-46.


The small molecule harmine is an antidiabetic cell-type-specific regulator of PPARgamma expression.

Waki H, Park KW, Mitro N, Pei L, Damoiseaux R, Wilpitz DC, Reue K, Saez E, Tontonoz P.

Cell Metab. 2007 May;5(5):357-70.


NR4A orphan nuclear receptors are transcriptional regulators of hepatic glucose metabolism.

Pei L, Waki H, Vaitheesvaran B, Wilpitz DC, Kurland IJ, Tontonoz P.

Nat Med. 2006 Sep;12(9):1048-55. Epub 2006 Aug 13.


Activation of liver X receptor improves glucose tolerance through coordinate regulation of glucose metabolism in liver and adipose tissue.

Laffitte BA, Chao LC, Li J, Walczak R, Hummasti S, Joseph SB, Castrillo A, Wilpitz DC, Mangelsdorf DJ, Collins JL, Saez E, Tontonoz P.

Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5419-24. Epub 2003 Apr 15.


Autoregulation of the human liver X receptor alpha promoter.

Laffitte BA, Joseph SB, Walczak R, Pei L, Wilpitz DC, Collins JL, Tontonoz P.

Mol Cell Biol. 2001 Nov;21(22):7558-68.


LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes.

Laffitte BA, Repa JJ, Joseph SB, Wilpitz DC, Kast HR, Mangelsdorf DJ, Tontonoz P.

Proc Natl Acad Sci U S A. 2001 Jan 16;98(2):507-12. Epub 2001 Jan 9.


Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXR alpha.

Venkateswaran A, Laffitte BA, Joseph SB, Mak PA, Wilpitz DC, Edwards PA, Tontonoz P.

Proc Natl Acad Sci U S A. 2000 Oct 24;97(22):12097-102.

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