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Items: 1 to 50 of 308

1.

Intraoperative Three-dimensional Virtual Reality and Computed Tomographic Guidance in Temporomandibular Joint Arthroplasty of Syndromic Craniofacial Dysostoses.

Bradley D, Willson T, Chang JB, Gandolfi B, Zhu TR, Bradley JP, Lee JC.

Plast Reconstr Surg Glob Open. 2019 Sep 10;7(9):e2388. doi: 10.1097/GOX.0000000000002388. eCollection 2019 Sep.

2.

Towards the Development of an In vivo Chemical Probe for Cyclin G Associated Kinase (GAK).

Asquith CRM, Bennett JM, Su L, Laitinen T, Elkins JM, Pickett JE, Wells CI, Li Z, Willson TM, Zuercher WJ.

Molecules. 2019 Nov 6;24(22). pii: E4016. doi: 10.3390/molecules24224016.

3.

Disease burden and cost of hidradenitis suppurativa: a retrospective examination of US administrative claims data.

Marvel J, Vlahiotis A, Sainski-Nguyen A, Willson T, Kimball A.

BMJ Open. 2019 Sep 30;9(9):e030579. doi: 10.1136/bmjopen-2019-030579.

4.

Gram-scale synthesis of FICZ, a photoreactive endogenous ligand of the aryl hydrocarbon receptor.

Zhang C, Creech KL, Zuercher WJ, Willson TM.

Sci Rep. 2019 Jul 10;9(1):9982. doi: 10.1038/s41598-019-46374-7.

5.

A Perspective on Extreme Open Science: Companies Sharing Compounds without Restriction.

Drewry DH, Wells CI, Zuercher WJ, Willson TM.

SLAS Discov. 2019 Jun;24(5):505-514. doi: 10.1177/2472555219838210. Epub 2019 Apr 29.

PMID:
31034310
6.

SGC-GAK-1: A Chemical Probe for Cyclin G Associated Kinase (GAK).

Asquith CRM, Berger BT, Wan J, Bennett JM, Capuzzi SJ, Crona DJ, Drewry DH, East MP, Elkins JM, Fedorov O, Godoi PH, Hunter DM, Knapp S, Müller S, Torrice CD, Wells CI, Earp HS, Willson TM, Zuercher WJ.

J Med Chem. 2019 Mar 14;62(5):2830-2836. doi: 10.1021/acs.jmedchem.8b01213. Epub 2019 Feb 26.

7.

Intraoperative Image-Guided Navigation in Craniofacial Surgery: Review and Grading of the Current Literature.

DeLong MR, Gandolfi BM, Barr ML, Datta N, Willson TD, Jarrahy R.

J Craniofac Surg. 2019 Mar/Apr;30(2):465-472. doi: 10.1097/SCS.0000000000005130.

PMID:
30640846
8.

WNT Activates the AAK1 Kinase to Promote Clathrin-Mediated Endocytosis of LRP6 and Establish a Negative Feedback Loop.

Agajanian MJ, Walker MP, Axtman AD, Ruela-de-Sousa RR, Serafin DS, Rabinowitz AD, Graham DM, Ryan MB, Tamir T, Nakamichi Y, Gammons MV, Bennett JM, Couñago RM, Drewry DH, Elkins JM, Gileadi C, Gileadi O, Godoi PH, Kapadia N, Müller S, Santiago AS, Sorrell FJ, Wells CI, Fedorov O, Willson TM, Zuercher WJ, Major MB.

Cell Rep. 2019 Jan 2;26(1):79-93.e8. doi: 10.1016/j.celrep.2018.12.023.

9.

Smchd1 Targeting to the Inactive X Is Dependent on the Xist-HnrnpK-PRC1 Pathway.

Jansz N, Nesterova T, Keniry A, Iminitoff M, Hickey PF, Pintacuda G, Masui O, Kobelke S, Geoghegan N, Breslin KA, Willson TA, Rogers K, Kay GF, Fox AH, Koseki H, Brockdorff N, Murphy JM, Blewitt ME.

Cell Rep. 2018 Nov 13;25(7):1912-1923.e9. doi: 10.1016/j.celrep.2018.10.044.

10.

Relationship between buprenorphine adherence and relapse, health care utilization and costs in privately and publicly insured patients with opioid use disorder.

Ronquest NA, Willson TM, Montejano LB, Nadipelli VR, Wollschlaeger BA.

Subst Abuse Rehabil. 2018 Sep 21;9:59-78. doi: 10.2147/SAR.S150253. eCollection 2018.

11.

Middle turbinate manipulation and postoperative sinus obstruction after endoscopic endonasal skull-base surgery.

Willson TJ, Rowan NR, Wang EW.

Int Forum Allergy Rhinol. 2018 Oct;8(10):1132-1135. doi: 10.1002/alr.22151. Epub 2018 Jun 19.

PMID:
29917327
12.

1,2,6-Thiadiazinones as Novel Narrow Spectrum Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CaMKK2) Inhibitors.

Asquith CRM, Godoi PH, Couñago RM, Laitinen T, Scott JW, Langendorf CG, Oakhill JS, Drewry DH, Zuercher WJ, Koutentis PA, Willson TM, Kalogirou AS.

Molecules. 2018 May 19;23(5). pii: E1221. doi: 10.3390/molecules23051221.

13.

Application of Integrated Drug Screening/Kinome Analysis to Identify Inhibitors of Gemcitabine-Resistant Pancreatic Cancer Cell Growth.

Krulikas LJ, McDonald IM, Lee B, Okumu DO, East MP, Gilbert TSK, Herring LE, Golitz BT, Wells CI, Axtman AD, Zuercher WJ, Willson TM, Kireev D, Yeh JJ, Johnson GL, Baines AT, Graves LM.

SLAS Discov. 2018 Sep;23(8):850-861. doi: 10.1177/2472555218773045. Epub 2018 May 9.

14.

Donated chemical probes for open science.

Müller S, Ackloo S, Arrowsmith CH, Bauser M, Baryza JL, Blagg J, Böttcher J, Bountra C, Brown PJ, Bunnage ME, Carter AJ, Damerell D, Dötsch V, Drewry DH, Edwards AM, Edwards J, Elkins JM, Fischer C, Frye SV, Gollner A, Grimshaw CE, IJzerman A, Hanke T, Hartung IV, Hitchcock S, Howe T, Hughes TV, Laufer S, Li VM, Liras S, Marsden BD, Matsui H, Mathias J, O'Hagan RC, Owen DR, Pande V, Rauh D, Rosenberg SH, Roth BL, Schneider NS, Scholten C, Singh Saikatendu K, Simeonov A, Takizawa M, Tse C, Thompson PR, Treiber DK, Viana AY, Wells CI, Willson TM, Zuercher WJ, Knapp S, Mueller-Fahrnow A.

Elife. 2018 Apr 20;7. pii: e34311. doi: 10.7554/eLife.34311.

15.

Circadian clock component REV-ERBα controls homeostatic regulation of pulmonary inflammation.

Pariollaud M, Gibbs JE, Hopwood TW, Brown S, Begley N, Vonslow R, Poolman T, Guo B, Saer B, Jones DH, Tellam JP, Bresciani S, Tomkinson NC, Wojno-Picon J, Cooper AW, Daniels DA, Trump RP, Grant D, Zuercher W, Willson TM, MacDonald AS, Bolognese B, Podolin PL, Sanchez Y, Loudon AS, Ray DW.

J Clin Invest. 2018 Jun 1;128(6):2281-2296. doi: 10.1172/JCI93910. Epub 2018 Apr 30.

16.

Development and validation of a claims-based approach to proxy ECOG performance status across ten tumor groups.

Sheffield KM, Bowman L, Smith DM, Li L, Hess LM, Montejano LB, Willson TM, Davidoff AJ.

J Comp Eff Res. 2018 Mar;7(3):193-208. doi: 10.2217/cer-2017-0040. Epub 2018 Mar 13.

PMID:
29533694
17.

The association of air pollutants and allergic and nonallergic rhinitis in chronic rhinosinusitis.

Mady LJ, Schwarzbach HL, Moore JA, Boudreau RM, Kaffenberger TM, Willson TJ, Lee SE.

Int Forum Allergy Rhinol. 2018 Mar;8(3):369-376. doi: 10.1002/alr.22060. Epub 2017 Dec 11.

PMID:
29227043
18.

Air pollutants may be environmental risk factors in chronic rhinosinusitis disease progression.

Mady LJ, Schwarzbach HL, Moore JA, Boudreau RM, Tripathy S, Kinnee E, Dodson ZM, Willson TJ, Clougherty JE, Lee SE.

Int Forum Allergy Rhinol. 2018 Mar;8(3):377-384. doi: 10.1002/alr.22052. Epub 2017 Dec 6. Erratum in: Int Forum Allergy Rhinol. 2018 Apr;8(4):553.

PMID:
29210519
19.

Quantitative, Wide-Spectrum Kinase Profiling in Live Cells for Assessing the Effect of Cellular ATP on Target Engagement.

Vasta JD, Corona CR, Wilkinson J, Zimprich CA, Hartnett JR, Ingold MR, Zimmerman K, Machleidt T, Kirkland TA, Huwiler KG, Ohana RF, Slater M, Otto P, Cong M, Wells CI, Berger BT, Hanke T, Glas C, Ding K, Drewry DH, Huber KVM, Willson TM, Knapp S, Müller S, Meisenheimer PL, Fan F, Wood KV, Robers MB.

Cell Chem Biol. 2018 Feb 15;25(2):206-214.e11. doi: 10.1016/j.chembiol.2017.10.010. Epub 2017 Nov 22.

20.

Identification and Optimization of 4-Anilinoquinolines as Inhibitors of Cyclin G Associated Kinase.

Asquith CRM, Laitinen T, Bennett JM, Godoi PH, East MP, Tizzard GJ, Graves LM, Johnson GL, Dornsife RE, Wells CI, Elkins JM, Willson TM, Zuercher WJ.

ChemMedChem. 2018 Jan 8;13(1):48-66. doi: 10.1002/cmdc.201700663. Epub 2017 Nov 27.

21.

Characteristics and treatment patterns of US commercially insured and Medicaid patients with opioid dependence or abuse.

Wollschlaeger BA, Willson TM, Montejano LB, Ronquest NA, Nadipelli VR.

J Opioid Manag. 2017 Jul/Aug;13(4):207-220. doi: 10.5055/jom.2017.0389.

PMID:
28953313
22.

Progress towards a public chemogenomic set for protein kinases and a call for contributions.

Drewry DH, Wells CI, Andrews DM, Angell R, Al-Ali H, Axtman AD, Capuzzi SJ, Elkins JM, Ettmayer P, Frederiksen M, Gileadi O, Gray N, Hooper A, Knapp S, Laufer S, Luecking U, Michaelides M, Müller S, Muratov E, Denny RA, Saikatendu KS, Treiber DK, Zuercher WJ, Willson TM.

PLoS One. 2017 Aug 2;12(8):e0181585. doi: 10.1371/journal.pone.0181585. eCollection 2017.

23.

Tapinarof Is a Natural AhR Agonist that Resolves Skin Inflammation in Mice and Humans.

Smith SH, Jayawickreme C, Rickard DJ, Nicodeme E, Bui T, Simmons C, Coquery CM, Neil J, Pryor WM, Mayhew D, Rajpal DK, Creech K, Furst S, Lee J, Wu D, Rastinejad F, Willson TM, Viviani F, Morris DC, Moore JT, Cote-Sierra J.

J Invest Dermatol. 2017 Oct;137(10):2110-2119. doi: 10.1016/j.jid.2017.05.004. Epub 2017 Jun 6.

24.

A Case Report and Systematic Review of Eosinophilic Angiocentric Fibrosis of the Paranasal Sinuses.

Heft Neal ME, Rowan NR, Willson TJ, Wang EW, Lee SE.

Ann Otol Rhinol Laryngol. 2017 May;126(5):415-423. doi: 10.1177/0003489417696510. Epub 2017 Mar 1. Review.

PMID:
28397561
25.

Monoclonal Antibodies for the Treatment of Nasal Polyps.

Willson TJ, Naclerio RM, Lee SE.

Immunol Allergy Clin North Am. 2017 May;37(2):357-367. doi: 10.1016/j.iac.2017.01.008. Epub 2017 Mar 2. Review.

PMID:
28366482
26.

Conserved IKAROS-regulated genes associated with B-progenitor acute lymphoblastic leukemia outcome.

Witkowski MT, Hu Y, Roberts KG, Boer JM, McKenzie MD, Liu GJ, Le Grice OD, Tremblay CS, Ghisi M, Willson TA, Horstmann MA, Aifantis I, Cimmino L, Frietze S, den Boer ML, Mullighan CG, Smyth GK, Dickins RA.

J Exp Med. 2017 Mar 6;214(3):773-791. doi: 10.1084/jem.20160048. Epub 2017 Feb 11.

27.

Anatomic Considerations for Sinonasal and Ventral Skull Base Malignancy.

Willson TJ, Fernandez-Miranda JC, Ferrareze Nunes C, Lieber S, Wang EW.

Otolaryngol Clin North Am. 2017 Apr;50(2):245-255. doi: 10.1016/j.otc.2016.12.003. Epub 2017 Jan 16. Review.

PMID:
28104275
28.

A systematic review of sinonasal oncocytomas and oncocytic carcinomas: Diagnosis, management, and technical considerations.

Hodzic Z, Rowan NR, Kashiwazaki R, Willson TJ, Wang EW, Lee SE.

Int Forum Allergy Rhinol. 2017 May;7(5):514-524. doi: 10.1002/alr.21902. Epub 2017 Jan 16. Review.

PMID:
28092140
29.

Fabrication and validation of a low-cost, medium-fidelity silicone injection molded endoscopic sinus surgery simulation model.

Chang DR, Lin RP, Bowe S, Bunegin L, Weitzel EK, McMains KC, Willson T, Chen PG.

Laryngoscope. 2017 Apr;127(4):781-786. doi: 10.1002/lary.26370. Epub 2016 Dec 21.

PMID:
28000224
30.

Development and Validation of an Algorithm to Identify Patients with Multiple Myeloma Using Administrative Claims Data.

Princic N, Gregory C, Willson T, Mahue M, Felici D, Werther W, Lenhart G, Foley KA.

Front Oncol. 2016 Oct 27;6:224. eCollection 2016.

31.

Aberrant position of nonrecurrent inferior laryngeal nerve: Report of 3 cases and a review of the literature.

Willson TJ, Stevens J, Salinas N, Brennan JA.

Ear Nose Throat J. 2016 Jun;95(6):E26-31. Review.

PMID:
27304449
32.

Comprehensive characterization of the Published Kinase Inhibitor Set.

Elkins JM, Fedele V, Szklarz M, Abdul Azeez KR, Salah E, Mikolajczyk J, Romanov S, Sepetov N, Huang XP, Roth BL, Al Haj Zen A, Fourches D, Muratov E, Tropsha A, Morris J, Teicher BA, Kunkel M, Polley E, Lackey KE, Atkinson FL, Overington JP, Bamborough P, Müller S, Price DJ, Willson TM, Drewry DH, Knapp S, Zuercher WJ.

Nat Biotechnol. 2016 Jan;34(1):95-103. doi: 10.1038/nbt.3374. Epub 2015 Oct 26.

PMID:
26501955
33.

Corrigendum: The promise and peril of chemical probes.

Arrowsmith CH, Audia JE, Austin C, Baell J, Bennett J, Blagg J, Bountra C, Brennan PE, Brown PJ, Bunnage ME, Buser-Doepner C, Campbell RM, Carter AJ, Cohen P, Copeland RA, Cravatt B, Dahlin JL, Dhanak D, Edwards AM, Frederiksen M, Frye SV, Gray N, Grimshaw CE, Hepworth D, Howe T, Huber KV, Jin J, Knapp S, Kotz JD, Kruger RG, Lowe D, Mader MM, Marsden B, Mueller-Fahrnow A, Müller S, O'Hagan RC, Overington JP, Owen DR, Rosenberg SH, Ross R, Roth B, Schapira M, Schreiber SL, Shoichet B, Sundström M, Superti-Furga G, Taunton J, Toledo-Sherman L, Walpole C, Walters MA, Willson TM, Workman P, Young RN, Zuercher WJ.

Nat Chem Biol. 2015 Nov;11(11):887. doi: 10.1038/nchembio1115-887c. No abstract available.

PMID:
26485080
34.

Quantifying Changes in Nasal Tip Support.

Willson TJ, Swiss T, Barrera JE.

JAMA Facial Plast Surg. 2015 Nov-Dec;17(6):428-32. doi: 10.1001/jamafacial.2015.1035.

PMID:
26379117
35.

Searching for Cedar: Geographic Variation in Single Aeroallergen Shows Dose Response in Internet Search Activity.

Willson TJ, Shams A, Lospinoso J, Weitzel E, McMains K.

Otolaryngol Head Neck Surg. 2015 Nov;153(5):770-4. doi: 10.1177/0194599815601650. Epub 2015 Sep 2.

PMID:
26340925
36.

The promise and peril of chemical probes.

Arrowsmith CH, Audia JE, Austin C, Baell J, Bennett J, Blagg J, Bountra C, Brennan PE, Brown PJ, Bunnage ME, Buser-Doepner C, Campbell RM, Carter AJ, Cohen P, Copeland RA, Cravatt B, Dahlin JL, Dhanak D, Edwards AM, Frederiksen M, Frye SV, Gray N, Grimshaw CE, Hepworth D, Howe T, Huber KV, Jin J, Knapp S, Kotz JD, Kruger RG, Lowe D, Mader MM, Marsden B, Mueller-Fahrnow A, Müller S, O'Hagan RC, Overington JP, Owen DR, Rosenberg SH, Roth B, Ross R, Schapira M, Schreiber SL, Shoichet B, Sundström M, Superti-Furga G, Taunton J, Toledo-Sherman L, Walpole C, Walters MA, Willson TM, Workman P, Young RN, Zuercher WJ.

Nat Chem Biol. 2015 Aug;11(8):536-41. doi: 10.1038/nchembio.1867. No abstract available. Erratum in: Nat Chem Biol. 2015 Aug;11(8):541. Roth, Brian [Corrected to Roth, Bryan] and Frederiksen, Mathias [Added]. Nat Chem Biol. 2015 Nov;11(11):887.

37.

Effect of environmental factors on Internet searches related to sinusitis.

Willson TJ, Lospinoso J, Weitzel EK, McMains KC.

Laryngoscope. 2015 Nov;125(11):2447-50. doi: 10.1002/lary.25420. Epub 2015 Jun 24.

PMID:
26108699
38.

Correction for Zhang et al., The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation.

Zhang JG, Farley A, Nicholson SE, Willson TA, Zugaro LM, Simpson RJ, Moritz RL, Cary D, Richardson R, Hausmann G, Kile BT, Kent SB, Alexander WS, Metcalf D, Hilton DJ, Nicola NA, Baca M.

Proc Natl Acad Sci U S A. 2015 Jun 2;112(22):E2979. doi: 10.1073/pnas.1507812112. Epub 2015 May 8. No abstract available.

39.

Analysis of osteoporosis treatment patterns with bisphosphonates and outcomes among postmenopausal veterans.

LaFleur J, DuVall SL, Willson T, Ginter T, Patterson O, Cheng Y, Knippenberg K, Haroldsen C, Adler RA, Curtis JR, Agodoa I, Nelson RE.

Bone. 2015 Sep;78:174-85. doi: 10.1016/j.bone.2015.04.022. Epub 2015 Apr 17.

PMID:
25896952
40.

Discovery and Characterization of GSK2801, a Selective Chemical Probe for the Bromodomains BAZ2A and BAZ2B.

Chen P, Chaikuad A, Bamborough P, Bantscheff M, Bountra C, Chung CW, Fedorov O, Grandi P, Jung D, Lesniak R, Lindon M, Müller S, Philpott M, Prinjha R, Rogers C, Selenski C, Tallant C, Werner T, Willson TM, Knapp S, Drewry DH.

J Med Chem. 2016 Feb 25;59(4):1410-24. doi: 10.1021/acs.jmedchem.5b00209. Epub 2015 Apr 6.

41.

The clinical epidemiology of male osteoporosis: a review of the recent literature.

Willson T, Nelson SD, Newbold J, Nelson RE, LaFleur J.

Clin Epidemiol. 2015 Jan 9;7:65-76. doi: 10.2147/CLEP.S40966. eCollection 2015. Review.

42.

Activated Notch counteracts Ikaros tumor suppression in mouse and human T-cell acute lymphoblastic leukemia.

Witkowski MT, Cimmino L, Hu Y, Trimarchi T, Tagoh H, McKenzie MD, Best SA, Tuohey L, Willson TA, Nutt SL, Busslinger M, Aifantis I, Smyth GK, Dickins RA.

Leukemia. 2015 Jun;29(6):1301-11. doi: 10.1038/leu.2015.27. Epub 2015 Feb 6.

43.

Factors influencing 30-day emergency visits and readmissions after sleeve gastrectomy: results from a community bariatric center.

Willson TD, Gomberawalla A, Mahoney K, Lutfi RE.

Obes Surg. 2015 Jun;25(6):975-81. doi: 10.1007/s11695-014-1546-x.

PMID:
25528568
44.

Correlating regional aeroallergen effects on internet search activity.

Willson TJ, Lospinoso J, Weitzel E, McMains K.

Otolaryngol Head Neck Surg. 2015 Feb;152(2):228-32. doi: 10.1177/0194599814560149. Epub 2014 Dec 12.

PMID:
25505261
45.

Impact of conditional deletion of the pro-apoptotic BCL-2 family member BIM in mice.

Herold MJ, Stuchbery R, Mérino D, Willson T, Strasser A, Hildeman D, Bouillet P.

Cell Death Dis. 2014 Oct 9;5:e1446. doi: 10.1038/cddis.2014.409.

46.

Air travel with known pneumocephalus following outpatient sinus surgery.

Willson TJ, Grady C, Braxton E, Weitzel E.

Aviat Space Environ Med. 2014 Jan;85(1):75-7.

PMID:
24479264
47.

Functional characterization of c-Mpl ectodomain mutations that underlie congenital amegakaryocytic thrombocytopenia.

Varghese LN, Zhang JG, Young SN, Willson TA, Alexander WS, Nicola NA, Babon JJ, Murphy JM.

Growth Factors. 2014 Feb;32(1):18-26. doi: 10.3109/08977194.2013.874347. Epub 2014 Jan 20.

PMID:
24438083
48.

Unusual metastatic patterns of invasive lobular carcinoma of the breast.

Sobinsky JD, Willson TD, Podbielski FJ, Connolly MM.

Case Rep Oncol Med. 2013;2013:986517. doi: 10.1155/2013/986517. Epub 2013 Nov 10.

49.

Seeding collaborations to advance kinase science with the GSK Published Kinase Inhibitor Set (PKIS).

Drewry DH, Willson TM, Zuercher WJ.

Curr Top Med Chem. 2014;14(3):340-2. Review.

50.

Completely humanizing prolactin rescues infertility in prolactin knockout mice and leads to human prolactin expression in extrapituitary mouse tissues.

Christensen HR, Murawsky MK, Horseman ND, Willson TA, Gregerson KA.

Endocrinology. 2013 Dec;154(12):4777-89. doi: 10.1210/en.2013-1476. Epub 2013 Sep 12.

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