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Items: 1 to 50 of 127

1.

Fragment Hits: What do They Look Like and How do They Bind?

Giordanetto F, Jin C, Willmore L, Feher M, Shaw DE.

J Med Chem. 2019 Apr 11;62(7):3381-3394. doi: 10.1021/acs.jmedchem.8b01855. Epub 2019 Apr 1.

2.

Fast animal pose estimation using deep neural networks.

Pereira TD, Aldarondo DE, Willmore L, Kislin M, Wang SS, Murthy M, Shaevitz JW.

Nat Methods. 2019 Jan;16(1):117-125. doi: 10.1038/s41592-018-0234-5. Epub 2018 Dec 20.

PMID:
30573820
3.

DULIP: A Dual Luminescence-Based Co-Immunoprecipitation Assay for Interactome Mapping in Mammalian Cells.

Trepte P, Buntru A, Klockmeier K, Willmore L, Arumughan A, Secker C, Zenkner M, Brusendorf L, Rau K, Redel A, Wanker EE.

J Mol Biol. 2015 Oct 23;427(21):3375-88. doi: 10.1016/j.jmb.2015.08.003. Epub 2015 Aug 8.

PMID:
26264872
4.

Monitoring and antiepileptic drug safety.

Willmore LJ.

Continuum (Minneap Minn). 2013 Jun;19(3 Epilepsy):801-5. doi: 10.1212/01.CON.0000431392.31476.9e. Review.

PMID:
23739112
5.

Hippocampal gene expression profiling in a rat model of posttraumatic epilepsy reveals temporal upregulation of lipid metabolism-related genes.

Ueda Y, Kitamoto A, Willmore LJ, Kojima T.

Neurochem Res. 2013 Jul;38(7):1399-406. doi: 10.1007/s11064-013-1037-9. Epub 2013 Apr 13.

PMID:
23585123
6.

Posttraumatic epilepsy.

Da Silva AM, Willmore LJ.

Handb Clin Neurol. 2012;108:585-99. doi: 10.1016/B978-0-444-52899-5.00017-4. No abstract available.

PMID:
22939055
7.

Posttraumatic Epilepsy: What's Contusion Got to Do With It?

Willmore LJ.

Epilepsy Curr. 2012 May;12(3):87-91. doi: 10.5698/1535-7511-12.3.87.

8.

Role of endoplasmic reticulum stress in the amygdaloid kindling model of rats.

Chihara Y, Ueda Y, Doi T, Willmore LJ.

Neurochem Res. 2011 Oct;36(10):1834-9. doi: 10.1007/s11064-011-0501-7. Epub 2011 May 22.

PMID:
21604154
9.

Hippocampal gene network analysis in an experimental model of posttraumatic epilepsy.

Ueda Y, Kitamoto A, Willmore LJ, Kojima T.

Neurochem Res. 2011 Jul;36(7):1323-8. doi: 10.1007/s11064-010-0386-x. Epub 2010 Dec 30.

PMID:
21191651
10.

Differential molecular regulation of glutamate in kindling resistant rats.

Doi T, Ueda Y, Takaki M, Willmore LJ.

Brain Res. 2011 Feb 23;1375:1-6. doi: 10.1016/j.brainres.2010.11.085. Epub 2010 Dec 4.

PMID:
21138736
11.

Epilepsy and trauma: a persistent challenge.

Willmore LJ, Lowenstein DH.

Neurology. 2010 Jul 20;75(3):202-3. doi: 10.1212/WNL.0b013e3181e8e94f. No abstract available.

PMID:
20644147
12.

Use of a new antiepileptic drug or an old one as first drug for treatment of absence epilepsy.

Penovich PE, Willmore LJ.

Epilepsia. 2009 Sep;50 Suppl 8:37-41. doi: 10.1111/j.1528-1167.2009.02234.x.

13.

Levetiracetam enhances endogenous antioxidant in the hippocampus of rats: in vivo evaluation by brain microdialysis combined with ESR spectroscopy.

Ueda Y, Doi T, Takaki M, Nagatomo K, Nakajima A, Willmore LJ.

Brain Res. 2009 Apr 17;1266:1-7. doi: 10.1016/j.brainres.2009.02.040. Epub 2009 Mar 4.

PMID:
19268434
14.

Vigabatrin: 2008 update.

Willmore LJ, Abelson MB, Ben-Menachem E, Pellock JM, Shields WD.

Epilepsia. 2009 Feb;50(2):163-73. Review.

15.

Role of glutamate and GABA transporters in development of pentylenetetrazol-kindling.

Doi T, Ueda Y, Nagatomo K, Willmore LJ.

Neurochem Res. 2009 Jul;34(7):1324-31. doi: 10.1007/s11064-009-9912-0. Epub 2009 Jan 24.

PMID:
19169815
16.

Posttraumatic epilepsy: hemorrhage, free radicals and the molecular regulation of glutamate.

Willmore LJ, Ueda Y.

Neurochem Res. 2009 Apr;34(4):688-97. doi: 10.1007/s11064-008-9841-3. Epub 2008 Sep 11. Review.

PMID:
18785008
17.

In vivo EPR estimation of bilateral hippocampal antioxidant ability of rats with epileptogenesis induced by amygdalar FeCl3 microinjection.

Ueda Y, Yokoyama H, Nakajima A, Takaki M, Nagatomo K, Doi T, Willmore LJ.

Epilepsia. 2007 Oct;48(10):1947-51. Epub 2007 Jun 9.

18.

Functional role for redox in the epileptogenesis: molecular regulation of glutamate in the hippocampus of FeCl3-induced limbic epilepsy model.

Ueda Y, Doi T, Nagatomo K, Willmore LJ, Nakajima A.

Exp Brain Res. 2007 Aug;181(4):571-7. Epub 2007 May 8.

PMID:
17486325
19.

Effect of levetiracetam on molecular regulation of hippocampal glutamate and GABA transporters in rats with chronic seizures induced by amygdalar FeCl3 injection.

Ueda Y, Doi T, Nagatomo K, Tokumaru J, Takaki M, Willmore LJ.

Brain Res. 2007 Jun 2;1151:55-61. Epub 2007 Mar 13.

PMID:
17408599
20.

Predictive value of hippocampal MR imaging-based high-dimensional mapping in mesial temporal epilepsy: preliminary findings.

Hogan RE, Wang L, Bertrand ME, Willmore LJ, Bucholz RD, Nassif AS, Csernansky JG.

AJNR Am J Neuroradiol. 2006 Nov-Dec;27(10):2149-54.

21.

Zonisamide - a review of experience and use in partial seizures.

Wilfong AA, Willmore LJ.

Neuropsychiatr Dis Treat. 2006 Sep;2(3):269-80.

22.

Molecular regulation of glutamate and GABA transporter proteins by clobazam during epileptogenesis in Fe(+++)-induced epileptic rats.

Doi T, Ueda Y, Tokumaru J, Willmore LJ.

Brain Res Mol Brain Res. 2005 Dec 14;142(2):91-6. Epub 2005 Nov 7.

PMID:
16274841
23.

Antiepileptic drugs and neuroprotection: current status and future roles.

Willmore LJ.

Epilepsy Behav. 2005 Dec;7 Suppl 3:S25-8. Epub 2005 Oct 18. Review.

PMID:
16239127
24.

Zonisamide overview of the United States experience.

Willmore LJ.

Seizure. 2004 Dec;13 Suppl 1:S57-8. Review. No abstract available.

25.

Natural antioxidants may prevent posttraumatic epilepsy: a proposal based on experimental animal studies.

Mori A, Yokoi I, Noda Y, Willmore LJ.

Acta Med Okayama. 2004 Jun;58(3):111-8. Review.

26.

MRI-based high-dimensional hippocampal mapping in mesial temporal lobe epilepsy.

Hogan RE, Wang L, Bertrand ME, Willmore LJ, Bucholz RD, Nassif AS, Csernansky JG.

Brain. 2004 Aug;127(Pt 8):1731-40. Epub 2004 Jul 1.

PMID:
15231583
27.

Divalproex and epilepsy.

Willmore LJ.

Psychopharmacol Bull. 2003;37 Suppl 2:43-53. Review.

PMID:
15021860
28.
29.

Molecular biology and genetics of epilepsy.

Willmore LJ, Ueda Y.

Acta Med Okayama. 2002 Apr;56(2):57-68. Review.

30.

Genetics of epilepsy.

Willmore LJ, Ueda Y.

J Child Neurol. 2002 Jan;17 Suppl 1:S18-27. Review.

PMID:
11918459
31.

Treatment of benign epilepsy syndromes throughout life.

Willmore LJ.

Epilepsia. 2001;42 Suppl 8:6-9. Review.

32.

Losigamone. Dr Willmar Schwabe.

Willmore LJ.

Curr Opin Investig Drugs. 2001 Dec;2(12):1763-6. Review.

PMID:
11892943
33.

Lamotrigine.

Willmore LJ.

Expert Rev Neurother. 2001 Sep;1(1):33-42. doi: 10.1586/14737175.1.1.33.

PMID:
19811044
34.

Idiopathic cardiac asystole presenting as an intractable adult onset partial seizure disorder.

Venkataraman V, Wheless JW, Willmore LJ, Motookal H.

Seizure. 2001 Jul;10(5):359-64.

35.

Sequential changes in AMPA and NMDA protein levels during Fe(3+)-induced epileptogenesis.

Doi T, Ueda Y, Tokumaru J, Mitsuyama Y, Willmore LJ.

Brain Res Mol Brain Res. 2001 Aug 15;92(1-2):107-14.

PMID:
11483247
36.

Choice and use of newer anticonvulsant drugs in older patients.

Willmore LJ.

Drugs Aging. 2000 Dec;17(6):441-52. Review.

PMID:
11200305
37.

Collapse of extracellular glutamate regulation during epileptogenesis: down-regulation and functional failure of glutamate transporter function in rats with chronic seizures induced by kainic acid.

Ueda Y, Doi T, Tokumaru J, Yokoyama H, Nakajima A, Mitsuyama Y, Ohya-Nishiguchi H, Kamada H, Willmore LJ.

J Neurochem. 2001 Feb;76(3):892-900.

38.

Clinical pharmacology of new antiepileptic drugs.

Willmore LJ.

Neurology. 2000;55(11 Suppl 3):S17-24. Review.

PMID:
11147564
39.
41.
42.
43.

Efficacy of gabapentin as adjunctive therapy in a large, multicenter study. The Steps Study Group.

Morrell MJ, McLean MJ, Willmore LJ, Privitera MD, Faught RE, Holmes GL, Magnus L, Bernstein P, Rose-Legatt.

Seizure. 2000 Jun;9(4):241-8.

44.
45.

Sequential changes in glutamate transporter mRNA levels during Fe(3+)-induced epileptogenesis.

Doi T, Ueda Y, Tokumaru J, Mitsuyama Y, Willmore LJ.

Brain Res Mol Brain Res. 2000 Jan 10;75(1):105-12.

PMID:
10648893
46.

Oxcarbazepine in a monotherapy trial for partial seizures--placebo-controlled studies in neurology: where do they stop?

Schachter SC, Vazquez B, Fisher RS, Laxer KD, Combs-Cantrell D, Faught E, Willmore LJ, Morris GL, Ojemann L, Montouris GD.

Neurology. 1999 Dec 10;53(9):2211-2. No abstract available.

PMID:
10599816
47.

New antiepileptic drugs: basic science and clinical use in children and adults

Willmore LJ.

Epilepsia. 1999;40 Suppl 5:S1. No abstract available.

48.

Language dominance determined by magnetic source imaging: a comparison with the Wada procedure.

Breier JI, Simos PG, Zouridakis G, Wheless JW, Willmore LJ, Constantinou JE, Maggio WW, Papanicolaou AC.

Neurology. 1999 Sep 22;53(5):938-45.

PMID:
10496250
49.

Magnetoencephalographic mapping of the language-specific cortex.

Papanicolaou AC, Simos PG, Breier JI, Zouridakis G, Willmore LJ, Wheless JW, Constantinou JE, Maggio WW, Gormley WB.

J Neurosurg. 1999 Jan;90(1):85-93.

PMID:
10413160
50.

Safety and tolerability of gabapentin as adjunctive therapy in a large, multicenter study.

McLean MJ, Morrell MJ, Willmore LJ, Privitera MD, Faught RE, Holmes GL, Magnus-Miller L, Bernstein P, Rose-Legatt A.

Epilepsia. 1999 Jul;40(7):965-72.

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