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Items: 25

1.

KMT9 monomethylates histone H4 lysine 12 and controls proliferation of prostate cancer cells.

Metzger E, Wang S, Urban S, Willmann D, Schmidt A, Offermann A, Allen A, Sum M, Obier N, Cottard F, Ulferts S, Preca BT, Hermann B, Maurer J, Greschik H, Hornung V, Einsle O, Perner S, Imhof A, Jung M, Schüle R.

Nat Struct Mol Biol. 2019 May;26(5):361-371. doi: 10.1038/s41594-019-0219-9. Epub 2019 May 6.

PMID:
31061526
2.

The histone acetyltransferase inhibitor Nir regulates epidermis development.

Duteil D, Tourrette Y, Eberlin A, Willmann D, Patel D, Friedrichs N, Müller JM, Schüle R.

Development. 2018 Mar 21;145(6). pii: dev158543. doi: 10.1242/dev.158543.

3.

Lsd1 regulates skeletal muscle regeneration and directs the fate of satellite cells.

Tosic M, Allen A, Willmann D, Lepper C, Kim J, Duteil D, Schüle R.

Nat Commun. 2018 Jan 25;9(1):366. doi: 10.1038/s41467-017-02740-5.

4.

Structure-activity studies on N-Substituted tranylcypromine derivatives lead to selective inhibitors of lysine specific demethylase 1 (LSD1) and potent inducers of leukemic cell differentiation.

Schulz-Fincke J, Hau M, Barth J, Robaa D, Willmann D, Kürner A, Haas J, Greve G, Haydn T, Fulda S, Lübbert M, Lüdeke S, Berg T, Sippl W, Schüle R, Jung M.

Eur J Med Chem. 2018 Jan 20;144:52-67. doi: 10.1016/j.ejmech.2017.12.001. Epub 2017 Dec 6.

PMID:
29247860
5.

The histone code reader Spin1 controls skeletal muscle development.

Greschik H, Duteil D, Messaddeq N, Willmann D, Arrigoni L, Sum M, Jung M, Metzger D, Manke T, Günther T, Schüle R.

Cell Death Dis. 2017 Nov 23;8(11):e3173. doi: 10.1038/cddis.2017.468.

6.

Stye.

Willmann D, Patel BC, Melanson SW.

StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2019 Jan-.
2019 Apr 7.

7.

Corneal Injury.

Willmann D, Melanson SW.

StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2019 Jan-.
2019 Feb 19.

8.

KDM4 Inhibition Targets Breast Cancer Stem-like Cells.

Metzger E, Stepputtis SS, Strietz J, Preca BT, Urban S, Willmann D, Allen A, Zenk F, Iovino N, Bronsert P, Proske A, Follo M, Boerries M, Stickeler E, Xu J, Wallace MB, Stafford JA, Kanouni T, Maurer J, Schüle R.

Cancer Res. 2017 Nov 1;77(21):5900-5912. doi: 10.1158/0008-5472.CAN-17-1754. Epub 2017 Sep 7.

9.

Lsd1 prevents age-programed loss of beige adipocytes.

Duteil D, Tosic M, Willmann D, Georgiadi A, Kanouni T, Schüle R.

Proc Natl Acad Sci U S A. 2017 May 16;114(20):5265-5270. doi: 10.1073/pnas.1702641114. Epub 2017 May 1.

10.

Inactivation of Lsd1 triggers senescence in trophoblast stem cells by induction of Sirt4.

Castex J, Willmann D, Kanouni T, Arrigoni L, Li Y, Friedrich M, Schleicher M, Wöhrle S, Pearson M, Kraut N, Méret M, Manke T, Metzger E, Schüle R, Günther T.

Cell Death Dis. 2017 Feb 23;8(2):e2631. doi: 10.1038/cddis.2017.48.

11.

Overexpression of histone demethylase Fbxl10 leads to enhanced migration in mouse embryonic fibroblasts.

Rohde M, Sievers E, Janzer A, Willmann D, Egert A, Schorle H, Schüle R, Kirfel J.

Exp Cell Res. 2016 Nov 1;348(2):123-131. doi: 10.1016/j.yexcr.2016.08.026. Epub 2016 Sep 17.

PMID:
27646113
12.

Lsd1 Ablation Triggers Metabolic Reprogramming of Brown Adipose Tissue.

Duteil D, Tosic M, Lausecker F, Nenseth HZ, Müller JM, Urban S, Willmann D, Petroll K, Messaddeq N, Arrigoni L, Manke T, Kornfeld JW, Brüning JC, Zagoriy V, Meret M, Dengjel J, Kanouni T, Schüle R.

Cell Rep. 2016 Oct 18;17(4):1008-1021. doi: 10.1016/j.celrep.2016.09.053.

13.

Assembly of methylated KDM1A and CHD1 drives androgen receptor-dependent transcription and translocation.

Metzger E, Willmann D, McMillan J, Forne I, Metzger P, Gerhardt S, Petroll K, von Maessenhausen A, Urban S, Schott AK, Espejo A, Eberlin A, Wohlwend D, Schüle KM, Schleicher M, Perner S, Bedford MT, Jung M, Dengjel J, Flaig R, Imhof A, Einsle O, Schüle R.

Nat Struct Mol Biol. 2016 Feb;23(2):132-9. doi: 10.1038/nsmb.3153. Epub 2016 Jan 11.

PMID:
26751641
14.

Selective targeting of the BRG/PB1 bromodomains impairs embryonic and trophoblast stem cell maintenance.

Fedorov O, Castex J, Tallant C, Owen DR, Martin S, Aldeghi M, Monteiro O, Filippakopoulos P, Picaud S, Trzupek JD, Gerstenberger BS, Bountra C, Willmann D, Wells C, Philpott M, Rogers C, Biggin PC, Brennan PE, Bunnage ME, Schüle R, Günther T, Knapp S, Müller S.

Sci Adv. 2015 Nov 13;1(10):e1500723. doi: 10.1126/sciadv.1500723. eCollection 2015 Nov.

15.

The histone code reader SPIN1 controls RET signaling in liposarcoma.

Franz H, Greschik H, Willmann D, Ozretić L, Jilg CA, Wardelmann E, Jung M, Buettner R, Schüle R.

Oncotarget. 2015 Mar 10;6(7):4773-89.

16.

PRK1/PKN1 controls migration and metastasis of androgen-independent prostate cancer cells.

Jilg CA, Ketscher A, Metzger E, Hummel B, Willmann D, Rüsseler V, Drendel V, Imhof A, Jung M, Franz H, Hölz S, Krönig M, Müller JM, Schüle R.

Oncotarget. 2014 Dec 30;5(24):12646-64.

17.

LSD1 controls metastasis of androgen-independent prostate cancer cells through PXN and LPAR6.

Ketscher A, Jilg CA, Willmann D, Hummel B, Imhof A, Rüsseler V, Hölz S, Metzger E, Müller JM, Schüle R.

Oncogenesis. 2014 Oct 6;3:e120. doi: 10.1038/oncsis.2014.34.

18.

LSD1 promotes oxidative metabolism of white adipose tissue.

Duteil D, Metzger E, Willmann D, Karagianni P, Friedrichs N, Greschik H, Günther T, Buettner R, Talianidis I, Metzger D, Schüle R.

Nat Commun. 2014 Jun 10;5:4093. doi: 10.1038/ncomms5093.

19.

Heterogeneous Antibody-Based Activity Assay for Lysine Specific Demethylase 1 (LSD1) on a Histone Peptide Substrate.

Schmitt ML, Ladwein KI, Carlino L, Schulz-Fincke J, Willmann D, Metzger E, Schilcher P, Imhof A, Schüle R, Sippl W, Jung M.

J Biomol Screen. 2014 Jul;19(6):973-8. doi: 10.1177/1087057114529156. Epub 2014 Mar 31.

PMID:
24687155
20.

Nonpeptidic propargylamines as inhibitors of lysine specific demethylase 1 (LSD1) with cellular activity.

Schmitt ML, Hauser AT, Carlino L, Pippel M, Schulz-Fincke J, Metzger E, Willmann D, Yiu T, Barton M, Schüle R, Sippl W, Jung M.

J Med Chem. 2013 Sep 26;56(18):7334-42. doi: 10.1021/jm400792m. Epub 2013 Sep 5.

21.

Impairment of prostate cancer cell growth by a selective and reversible lysine-specific demethylase 1 inhibitor.

Willmann D, Lim S, Wetzel S, Metzger E, Jandausch A, Wilk W, Jung M, Forne I, Imhof A, Janzer A, Kirfel J, Waldmann H, Schüle R, Buettner R.

Int J Cancer. 2012 Dec 1;131(11):2704-9. doi: 10.1002/ijc.27555. Epub 2012 Jun 28.

22.

All-trans retinoic acid is a ligand for the orphan nuclear receptor ROR beta.

Stehlin-Gaon C, Willmann D, Zeyer D, Sanglier S, Van Dorsselaer A, Renaud JP, Moras D, Schüle R.

Nat Struct Biol. 2003 Oct;10(10):820-5. Epub 2003 Sep 7.

PMID:
12958591
23.

Systemic acute-phase reactants, C-reactive protein and haptoglobin, in adult periodontitis.

Ebersole JL, Machen RL, Steffen MJ, Willmann DE.

Clin Exp Immunol. 1997 Feb;107(2):347-52.

24.

Host response assessment in recurring periodontitis.

Ebersole JL, Cappelli D, Steffen MJ, Willmann DE, O'Dell DS.

J Clin Periodontol. 1996 Mar;23(3 Pt 2):258-62. Review.

PMID:
8707986
25.

A new prophylaxis instrument: effect on enamel alterations.

Willmann DE, Norling BK, Johnson WN.

J Am Dent Assoc. 1980 Dec;101(6):923-5.

PMID:
6935286

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