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Items: 1 to 50 of 438

1.

Metformin and JQ1 synergistically inhibit obesity-activated thyroid cancer.

Park S, Willingham MC, Qi J, Cheng SY.

Endocr Relat Cancer. 2018 Oct;25(10):865-877. doi: 10.1530/ERC-18-0071. Epub 2018 Jun 18.

PMID:
29914872
2.

Defective erythropoiesis caused by mutations of the thyroid hormone receptor α gene.

Park S, Han CR, Park JW, Zhao L, Zhu X, Willingham M, Bodine DM, Cheng SY.

PLoS Genet. 2017 Sep 14;13(9):e1006991. doi: 10.1371/journal.pgen.1006991. eCollection 2017 Sep.

3.

Triple low, double low: it's time to deal Achilles heel a single deadly blow.

Willingham MD, Avidan MS.

Br J Anaesth. 2017 Jul 1;119(1):1-4. doi: 10.1093/bja/aex132. No abstract available.

4.

Inhibition of STAT3 signaling blocks obesity-induced mammary hyperplasia in a mouse model.

Park JW, Zhao L, Willingham MC, Cheng SY.

Am J Cancer Res. 2017 Mar 1;7(3):727-739. eCollection 2017.

5.

Targeting MYC as a Therapeutic Intervention for Anaplastic Thyroid Cancer.

Enomoto K, Zhu X, Park S, Zhao L, Zhu YJ, Willingham MC, Qi J, Copland JA, Meltzer P, Cheng SY.

J Clin Endocrinol Metab. 2017 Jul 1;102(7):2268-2280. doi: 10.1210/jc.2016-3771.

6.

Bromodomain and Extraterminal Protein Inhibitor JQ1 Suppresses Thyroid Tumor Growth in a Mouse Model.

Zhu X, Enomoto K, Zhao L, Zhu YJ, Willingham MC, Meltzer P, Qi J, Cheng SY.

Clin Cancer Res. 2017 Jan 15;23(2):430-440. doi: 10.1158/1078-0432.CCR-16-0914. Epub 2016 Jul 20.

7.

Temple or Prison: Religious Beliefs and Attitudes Toward the Body.

Jacobson HL, Hall ME, Anderson TL, Willingham MM.

J Relig Health. 2016 Dec;55(6):2154-73. doi: 10.1007/s10943-016-0266-z.

PMID:
27283045
8.

SAHA-induced loss of tumor suppressor Pten gene promotes thyroid carcinogenesis in a mouse model.

Zhu X, Kim DW, Zhao L, Willingham MC, Cheng SY.

Endocr Relat Cancer. 2016 Jul;23(7):521-33. doi: 10.1530/ERC-16-0103. Epub 2016 Jun 7.

9.

Loss of tyrosine phosphorylation at Y406 abrogates the tumor suppressor functions of the thyroid hormone receptor β.

Park JW, Zhao L, Willingham MC, Cheng SY.

Mol Carcinog. 2017 Feb;56(2):489-498. doi: 10.1002/mc.22511. Epub 2016 Jun 14.

PMID:
27254276
10.

In Reply.

Willingham MD, Kheterpal S, Avidan MS.

Anesthesiology. 2016 Jun;124(6):1411-2. doi: 10.1097/ALN.0000000000001088. No abstract available.

PMID:
27187122
11.

Metformin blocks progression of obesity-activated thyroid cancer in a mouse model.

Park J, Kim WG, Zhao L, Enomoto K, Willingham M, Cheng SY.

Oncotarget. 2016 Jun 7;7(23):34832-44. doi: 10.18632/oncotarget.8989.

12.

Amnesia of the Operating Room in the B-Unaware and BAG-RECALL Clinical Trials.

Chen Y, Cai A, Dexter F, Pryor KO, Jacobsohn EM, Glick DB, Willingham MD, Escallier K, Winter A, Avidan MS.

Anesth Analg. 2016 Apr;122(4):1158-68.

PMID:
26859877
13.

Inhibition of STAT3 activity delays obesity-induced thyroid carcinogenesis in a mouse model.

Park JW, Han CR, Zhao L, Willingham MC, Cheng SY.

Endocr Relat Cancer. 2016 Jan;23(1):53-63. doi: 10.1530/ERC-15-0417. Epub 2015 Nov 9.

14.

Concurrence of Intraoperative Hypotension, Low Minimum Alveolar Concentration, and Low Bispectral Index Is Associated with Postoperative Death.

Willingham MD, Karren E, Shanks AM, O'Connor MF, Jacobsohn E, Kheterpal S, Avidan MS.

Anesthesiology. 2015 Oct;123(4):775-85. doi: 10.1097/ALN.0000000000000822.

15.

F10 Inhibits Growth of PC3 Xenografts and Enhances the Effects of Radiation Therapy.

Gmeiner WH, Willingham MC, Bourland JD, Hatcher HC, Smith TL, D'Agostino RB Jr, Blackstock W.

J Clin Oncol Res. 2014 Jul-Aug;2(4). pii: 1028.

16.

Oncogenic mutations of thyroid hormone receptor β.

Park JW, Zhao L, Willingham M, Cheng SY.

Oncotarget. 2015 Apr 10;6(10):8115-31.

17.

Testosterone regulates thyroid cancer progression by modifying tumor suppressor genes and tumor immunity.

Zhang LJ, Xiong Y, Nilubol N, He M, Bommareddi S, Zhu X, Jia L, Xiao Z, Park JW, Xu X, Patel D, Willingham MC, Cheng SY, Kebebew E.

Carcinogenesis. 2015 Apr;36(4):420-8. doi: 10.1093/carcin/bgv001. Epub 2015 Jan 9.

18.

DMP1β, a splice isoform of the tumour suppressor DMP1 locus, induces proliferation and progression of breast cancer.

Maglic D, Stovall DB, Cline JM, Fry EA, Mallakin A, Taneja P, Caudell DL, Willingham MC, Sui G, Inoue K.

J Pathol. 2015 May;236(1):90-102. doi: 10.1002/path.4504. Epub 2015 Feb 9.

19.

Synergistic signaling of KRAS and thyroid hormone receptor β mutants promotes undifferentiated thyroid cancer through MYC up-regulation.

Zhu X, Zhao L, Park JW, Willingham MC, Cheng SY.

Neoplasia. 2014 Sep;16(9):757-69. doi: 10.1016/j.neo.2014.08.003.

20.

Association between intraoperative electroencephalographic suppression and postoperative mortality.

Willingham M, Ben Abdallah A, Gradwohl S, Helsten D, Lin N, Villafranca A, Jacobsohn E, Avidan M, Kaiser H.

Br J Anaesth. 2014 Dec;113(6):1001-8. doi: 10.1093/bja/aeu105. Epub 2014 May 22.

21.

Impact of right-handedness on anaesthetic sensitivity, intra-operative awareness and postoperative mortality.

Rao S, Huverserian AR, Ben Abdallah A, Lees K, Willingham MD, Burnside BA, Villafranca AJ, Glick DB, Jacobsohn E, Avidan MS.

Anaesthesia. 2014 Aug;69(8):840-6. doi: 10.1111/anae.12676. Epub 2014 May 12.

22.

A histone deacetylase inhibitor improves hypothyroidism caused by a TRα1 mutant.

Kim DW, Park JW, Willingham MC, Cheng SY.

Hum Mol Genet. 2014 May 15;23(10):2651-64. doi: 10.1093/hmg/ddt660. Epub 2013 Dec 30.

23.

Molecular determinants of susceptibility to oncolytic vesicular stomatitis virus in pancreatic adenocarcinoma.

Blackham AU, Northrup SA, Willingham M, Sirintrapun J, Russell GB, Lyles DS, Stewart JH 4th.

J Surg Res. 2014 Apr;187(2):412-26. doi: 10.1016/j.jss.2013.10.032. Epub 2013 Oct 21.

24.

MYRF is a membrane-associated transcription factor that autoproteolytically cleaves to directly activate myelin genes.

Bujalka H, Koenning M, Jackson S, Perreau VM, Pope B, Hay CM, Mitew S, Hill AF, Lu QR, Wegner M, Srinivasan R, Svaren J, Willingham M, Barres BA, Emery B.

PLoS Biol. 2013;11(8):e1001625. doi: 10.1371/journal.pbio.1001625. Epub 2013 Aug 13.

25.

Oncogenic Actions of the Nuclear Receptor Corepressor (NCOR1) in a Mouse Model of Thyroid Cancer.

Fozzatti L, Park JW, Zhao L, Willingham MC, Cheng SY.

PLoS One. 2013 Jun 26;8(6):e67954. doi: 10.1371/journal.pone.0067954. Print 2013.

26.

Diet-induced obesity increases tumor growth and promotes anaplastic change in thyroid cancer in a mouse model.

Kim WG, Park JW, Willingham MC, Cheng SY.

Endocrinology. 2013 Aug;154(8):2936-47. doi: 10.1210/en.2013-1128. Epub 2013 Jun 7.

27.

Inhibition of tumorigenesis by the thyroid hormone receptor β in xenograft models.

Kim WG, Zhao L, Kim DW, Willingham MC, Cheng SY.

Thyroid. 2014 Feb;24(2):260-9. doi: 10.1089/thy.2013.0054. Epub 2013 Sep 4.

28.

Interactions between immunity, proliferation and molecular subtype in breast cancer prognosis.

Nagalla S, Chou JW, Willingham MC, Ruiz J, Vaughn JP, Dubey P, Lash TL, Hamilton-Dutoit SJ, Bergh J, Sotiriou C, Black MA, Miller LD.

Genome Biol. 2013 Apr 29;14(4):R34. doi: 10.1186/gb-2013-14-4-r34.

29.

Nuclear receptor corepressor (NCOR1) regulates in vivo actions of a mutated thyroid hormone receptor α.

Fozzatti L, Kim DW, Park JW, Willingham MC, Hollenberg AN, Cheng SY.

Proc Natl Acad Sci U S A. 2013 May 7;110(19):7850-5. doi: 10.1073/pnas.1222334110. Epub 2013 Apr 22.

30.

Obstructive sleep apnea screening and postoperative mortality in a large surgical cohort.

Lockhart EM, Willingham MD, Abdallah AB, Helsten DL, Bedair BA, Thomas J, Duntley S, Avidan MS.

Sleep Med. 2013 May;14(5):407-15. doi: 10.1016/j.sleep.2012.10.018. Epub 2013 Mar 13.

31.

Variation in susceptibility of human malignant melanomas to oncolytic vesicular stomatitis virus.

Blackham AU, Northrup SA, Willingham M, D'Agostino RB Jr, Lyles DS, Stewart JH 4th.

Surgery. 2013 Mar;153(3):333-43. doi: 10.1016/j.surg.2012.09.003. Epub 2012 Oct 25.

32.

Prognostic value of the hDMP1-ARF-Hdm2-p53 pathway in breast cancer.

Maglic D, Zhu S, Fry EA, Taneja P, Kai F, Kendig RD, Sugiyama T, Miller LD, Willingham MC, Inoue K.

Oncogene. 2013 Aug 29;32(35):4120-9. doi: 10.1038/onc.2012.423. Epub 2012 Oct 8.

33.

Thyroid hormone receptor β suppresses SV40-mediated tumorigenesis via novel nongenomic actions.

Kim DW, Zhao L, Hanover J, Willingham M, Cheng SY.

Am J Cancer Res. 2012;2(5):606-19. Epub 2012 Aug 23.

34.

Myelin gene regulatory factor is required for maintenance of myelin and mature oligodendrocyte identity in the adult CNS.

Koenning M, Jackson S, Hay CM, Faux C, Kilpatrick TJ, Willingham M, Emery B.

J Neurosci. 2012 Sep 5;32(36):12528-42. doi: 10.1523/JNEUROSCI.1069-12.2012.

35.

Role of TSH in the spontaneous development of asymmetrical thyroid carcinoma in mice with a targeted mutation in a single allele of the thyroid hormone-β receptor.

Zhao L, Zhu X, Won Park J, Fozzatti L, Willingham M, Cheng SY.

Endocrinology. 2012 Oct;153(10):5090-100. Epub 2012 Aug 23.

36.

Angiotensin-(1-7) attenuates metastatic prostate cancer and reduces osteoclastogenesis.

Krishnan B, Smith TL, Dubey P, Zapadka ME, Torti FM, Willingham MC, Tallant EA, Gallagher PE.

Prostate. 2013 Jan;73(1):71-82. doi: 10.1002/pros.22542. Epub 2012 May 29.

37.

SKI-606, an Src inhibitor, reduces tumor growth, invasion, and distant metastasis in a mouse model of thyroid cancer.

Kim WG, Guigon CJ, Fozzatti L, Park JW, Lu C, Willingham MC, Cheng SY.

Clin Cancer Res. 2012 Mar 1;18(5):1281-90. doi: 10.1158/1078-0432.CCR-11-2892. Epub 2012 Jan 23.

38.

Resistance to thyroid hormone is modulated in vivo by the nuclear receptor corepressor (NCOR1).

Fozzatti L, Lu C, Kim DW, Park JW, Astapova I, Gavrilova O, Willingham MC, Hollenberg AN, Cheng SY.

Proc Natl Acad Sci U S A. 2011 Oct 18;108(42):17462-7. doi: 10.1073/pnas.1107474108. Epub 2011 Oct 10.

39.

Activation of tumor cell proliferation by thyroid hormone in a mouse model of follicular thyroid carcinoma.

Lu C, Zhu X, Willingham MC, Cheng SY.

Oncogene. 2012 Apr 19;31(16):2007-16. doi: 10.1038/onc.2011.390. Epub 2011 Sep 12.

40.

Iron uptake mediated by binding of H-ferritin to the TIM-2 receptor in mouse cells.

Han J, Seaman WE, Di X, Wang W, Willingham M, Torti FM, Torti SV.

PLoS One. 2011;6(8):e23800. doi: 10.1371/journal.pone.0023800. Epub 2011 Aug 19.

41.

Vesicular stomatitis virus as a treatment for colorectal cancer.

Stewart JH 4th, Ahmed M, Northrup SA, Willingham M, Lyles DS.

Cancer Gene Ther. 2011 Dec;18(12):837-49. doi: 10.1038/cgt.2011.49. Epub 2011 Sep 2.

42.

Novel innate cancer killing activity in humans.

Blanks MJ, Stehle JR Jr, Du W, Adams JM, Willingham MC, Allen GO, Hu JJ, Lovato J, Molnar I, Cui Z.

Cancer Cell Int. 2011 Aug 3;11:26. doi: 10.1186/1475-2867-11-26.

43.

Endogenous synthesis of n-3 polyunsaturated fatty acids in Fat-1 mice is associated with increased mammary gland and liver syndecan-1.

Sun H, Hu Y, Gu Z, Wilson MD, Chen YQ, Rudel LL, Willingham MC, Edwards IJ.

PLoS One. 2011;6(5):e20502. doi: 10.1371/journal.pone.0020502. Epub 2011 May 31.

44.
45.

Mutation of thyroid hormone receptor-β in mice predisposes to the development of mammary tumors.

Guigon CJ, Kim DW, Willingham MC, Cheng SY.

Oncogene. 2011 Jul 28;30(30):3381-90. doi: 10.1038/onc.2011.50. Epub 2011 Mar 14.

46.

Brain-derived neurotrophic factor promotes central nervous system myelination via a direct effect upon oligodendrocytes.

Xiao J, Wong AW, Willingham MM, van den Buuse M, Kilpatrick TJ, Murray SS.

Neurosignals. 2010;18(3):186-202. doi: 10.1159/000323170. Epub 2011 Jan 18.

47.

Loss of heterozygosity and SOSTDC1 in adult and pediatric renal tumors.

Blish KR, Clausen KA, Hawkins GA, Garvin AJ, Willingham MC, Turner JC, Torti FM, Torti SV.

J Exp Clin Cancer Res. 2010 Nov 16;29:147. doi: 10.1186/1756-9966-29-147.

48.

Critical roles of DMP1 in human epidermal growth factor receptor 2/neu-Arf-p53 signaling and breast cancer development.

Taneja P, Maglic D, Kai F, Sugiyama T, Kendig RD, Frazier DP, Willingham MC, Inoue K.

Cancer Res. 2010 Nov 15;70(22):9084-94. doi: 10.1158/0008-5472.CAN-10-0159. Epub 2010 Nov 9.

49.

Ferroportin and iron regulation in breast cancer progression and prognosis.

Pinnix ZK, Miller LD, Wang W, D'Agostino R Jr, Kute T, Willingham MC, Hatcher H, Tesfay L, Sui G, Di X, Torti SV, Torti FM.

Sci Transl Med. 2010 Aug 4;2(43):43ra56. doi: 10.1126/scisignal.3001127. Erratum in: Sci Transl Med. 2010 Aug 25;2(46):46er1.

50.

Elevation of oil body integrity and emulsion stability by polyoleosins, multiple oleosin units joined in tandem head-to-tail fusions.

Scott RW, Winichayakul S, Roldan M, Cookson R, Willingham M, Castle M, Pueschel R, Peng CC, Tzen JT, Roberts NJ.

Plant Biotechnol J. 2010 Oct;8(8):912-27. doi: 10.1111/j.1467-7652.2010.00522.x.

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