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Neurologic Morbidity in People with Cryptococcosis in Absence of HIV Infection: Response to Letter to the Editor.

Marr KA, Anjum S, Hammoud DA, Williamson PR.

Clin Infect Dis. 2020 Mar 19. pii: ciaa297. doi: 10.1093/cid/ciaa297. [Epub ahead of print] No abstract available.


Moving Towards Common Data Elements and Core Outcome Measures in Frailty Research.

Muscedere J, Afilalo J, Araujo de Carvalho I, Cesari M, Clegg A, Eriksen HE, Evans KR, Heckman G, Hirdes JP, Kim PM, Laffon B, Lynn J, Martin F, Prorok JC, Rockwood K, Rodrigues Mañas L, Rolfson D, Shaw G, Shea B, Sinha S, Theou O, Tugwell P, Valdiglesias V, Vellas B, Veronese N, Wallace LMK, Williamson PR.

J Frailty Aging. 2020;9(1):14-22. doi: 10.14283/jfa.2019.43.


Where next for inhaled corticosteroids in childhood asthma?

Sinha IP, Dodd SR, Grime C, Hawcutt DB, Fernandes RM, Roberts MR, Simba JM, Williamson PR.

Lancet Respir Med. 2020 Apr;8(4):345. doi: 10.1016/S2213-2600(20)30013-8. Epub 2020 Jan 21. No abstract available.


Cauda Equina Syndrome Core Outcome Set (CESCOS): An international patient and healthcare professional consensus for research studies.

Srikandarajah N, Noble A, Clark S, Wilby M, Freeman BJC, Fehlings MG, Williamson PR, Marson T.

PLoS One. 2020 Jan 10;15(1):e0225907. doi: 10.1371/journal.pone.0225907. eCollection 2020.


Trial Forge Guidance 2: how to decide if a further Study Within A Trial (SWAT) is needed.

Treweek S, Bevan S, Bower P, Briel M, Campbell M, Christie J, Collett C, Cotton S, Devane D, El Feky A, Galvin S, Gardner H, Gillies K, Hood K, Jansen J, Littleford R, Parker A, Ramsay C, Restrup L, Sullivan F, Torgerson D, Tremain L, von Elm E, Westmore M, Williams H, Williamson PR, Clarke M.

Trials. 2020 Jan 7;21(1):33. doi: 10.1186/s13063-019-3980-5.


Selecting Core Outcomes for Randomised Effectiveness trials In Type 2 diabetes (SCORE-IT): a patient and healthcare professional consensus on a core outcome set for type 2 diabetes.

Harman NL, Wilding JPH, Curry D, Harris J, Logue J, Pemberton RJ, Perreault L, Thompson G, Tunis S, Williamson PR; SCORE-IT Study Team .

BMJ Open Diabetes Res Care. 2019 Dec 29;7(1):e000700. doi: 10.1136/bmjdrc-2019-000700. eCollection 2019.


A Systematic Review of Core Outcomes for Hypospadias Surgery.

Leunbach TL, O'Toole S, Springer A, Williamson PR, Ahmed SF.

Sex Dev. 2019 Dec 20. doi: 10.1159/000504973. [Epub ahead of print]


Quantifications of CSF Apoptotic Bodies Do Not Provide Clinical Value in Multiple Sclerosis.

Masvekar R, Mizrahi J, Park J, Williamson PR, Bielekova B.

Front Neurol. 2019 Nov 26;10:1241. doi: 10.3389/fneur.2019.01241. eCollection 2019.


PPI in research: a reflection from early stage researchers.

Biggane AM, Olsen M, Williamson PR.

Res Involv Engagem. 2019 Nov 19;5:35. doi: 10.1186/s40900-019-0170-2. eCollection 2019.


Choosing important health outcomes for comparative effectiveness research: 5th annual update to a systematic review of core outcome sets for research.

Gargon E, Gorst SL, Williamson PR.

PLoS One. 2019 Dec 12;14(12):e0225980. doi: 10.1371/journal.pone.0225980. eCollection 2019.


HIV-Negative Cryptococcal Meningoencephalitis Results in a Persistent Frontal-Subcortical Syndrome.

Traino K, Snow J, Ham L, Summers A, Segalà L, Shirazi T, Biassou N, Panackal A, Anjum S, Marr KA, Kreisl WC, Bennett JE, Williamson PR.

Sci Rep. 2019 Dec 5;9(1):18442. doi: 10.1038/s41598-019-54876-7.


Participating in core outcome set development via Delphi surveys: qualitative interviews provide pointers to inform guidance.

Biggane AM, Williamson PR, Ravaud P, Young B.

BMJ Open. 2019 Nov 14;9(11):e032338. doi: 10.1136/bmjopen-2019-032338.


Evaluation of an automatic article selection method for timelier updates of the Comet Core Outcome Set database.

Norman CR, Gargon E, Leeflang MMG, Névéol A, Williamson PR.

Database (Oxford). 2019 Jan 1;2019. pii: baz109. doi: 10.1093/database/baz109.


A review of current practice in the design and assessment of internal pilots in UK NIHR clinical trials.

Rosala-Hallas A, Gamble C, Blazeby J, Williamson PR.

Trials. 2019 Sep 18;20(1):571. doi: 10.1186/s13063-019-3669-9. Review.


Assessing the impact of a research funder's recommendation to consider core outcome sets.

Hughes KL, Kirkham JJ, Clarke M, Williamson PR.

PLoS One. 2019 Sep 13;14(9):e0222418. doi: 10.1371/journal.pone.0222418. eCollection 2019.


Protocols for the Analysis of microRNA Expression, Biogenesis, and Function in Immune Cells.

Zhang N, Hu G, Myers TG, Williamson PR.

Curr Protoc Immunol. 2019 Sep;126(1):e78. doi: 10.1002/cpim.78.


Intradural cauda equina Candida abscess presenting with hydrocephalus: case report.

Argersinger DP, Natkha VP, Shepard MJ, Thomas AA, Oler AJ, Williamson PR, Chittiboina P, Heiss JD.

J Neurosurg Spine. 2019 Aug 30:1-4. doi: 10.3171/2019.6.SPINE19271. [Epub ahead of print]


Improving therapy of severe infections through drug repurposing of synergistic combinations.

Cheng YS, Williamson PR, Zheng W.

Curr Opin Pharmacol. 2019 Oct;48:92-98. doi: 10.1016/j.coph.2019.07.006. Epub 2019 Aug 24. Review.


Industry funding was associated with increased use of core outcome sets.

Kirkham JJ, Bracken M, Hind L, Pennington K, Clarke M, Williamson PR.

J Clin Epidemiol. 2019 Nov;115:90-97. doi: 10.1016/j.jclinepi.2019.07.007. Epub 2019 Jul 18.


Audiologic and Otologic Complications of Cryptococcal Meningoencephalitis in Non-HIV Previously Healthy Patients.

King KA, Ansari G, Panackal AA, Zalewski C, Anjum S, Bennett JE, Beri A, Kim HJ, Hammoud D, Brewer CC, Williamson PR.

Otol Neurotol. 2019 Jul;40(6):e657-e664. doi: 10.1097/MAO.0000000000002242.


Efficacy of Oral Encochleated Amphotericin B in a Mouse Model of Cryptococcal Meningoencephalitis.

Lu R, Hollingsworth C, Qiu J, Wang A, Hughes E, Xin X, Konrath KM, Elsegeiny W, Park YD, Atakulu L, Craft JC, Tramont EC, Mannino R, Williamson PR.

mBio. 2019 May 28;10(3). pii: e00724-19. doi: 10.1128/mBio.00724-19.


Pirfenidone in Heart Failure with Preserved Ejection Fraction-Rationale and Design of the PIROUETTE Trial.

Lewis GA, Schelbert EB, Naish JH, Bedson E, Dodd S, Eccleson H, Clayton D, Jimenez BD, McDonagh T, Williams SG, Cooper A, Cunnington C, Ahmed FZ, Viswesvaraiah R, Russell S, Neubauer S, Williamson PR, Miller CA.

Cardiovasc Drugs Ther. 2019 Aug;33(4):461-470. doi: 10.1007/s10557-019-06876-y.


Protocol for the development of a core outcome set for cauda equina syndrome: systematic literature review, qualitative interviews, Delphi survey and consensus meeting.

Srikandarajah N, Noble AJ, Wilby M, Clark S, Williamson PR, Marson AG.

BMJ Open. 2019 May 1;9(4):e024002. doi: 10.1136/bmjopen-2018-024002.


Identifying Possible Outcome Domains from Existing Outcome Measures to Inform an OMERACT Core Domain Set for Safety in Rheumatology Trials.

Klokker L, Berthelsen DB, Woodworth T, Andersen KM, Furst DE, Devoe D, Williamson PR, Suarez-Almazor ME, Strand V, Leong AL, Goel N, Boers M, Brooks PM, March L, Sloan VS, Tugwell P, Simon LS, Christensen R.

J Rheumatol. 2019 Sep;46(9):1173-1178. doi: 10.3899/jrheum.190196. Epub 2019 May 1.


Adalimumab in combination with methotrexate for refractory uveitis associated with juvenile idiopathic arthritis: a RCT.

Ramanan AV, Dick AD, Jones AP, Hughes DA, McKay A, Rosala-Hallas A, Williamson PR, Hardwick B, Hickey H, Rainford N, Hickey G, Kolamunnage-Dona R, Culeddu G, Plumpton C, Wood E, Compeyrot-Lacassagne S, Woo P, Edelsten C, Beresford MW.

Health Technol Assess. 2019 Apr;23(15):1-140. doi: 10.3310/hta23150.


Improvement was needed in the standards of development for cancer core outcome sets.

Gargon E, Williamson PR, Blazeby JM, Kirkham JJ.

J Clin Epidemiol. 2019 Aug;112:36-44. doi: 10.1016/j.jclinepi.2019.04.006. Epub 2019 Apr 19.


What is important to people living with dementia?: the 'long-list' of outcome items in the development of a core outcome set for use in the evaluation of non-pharmacological community-based health and social care interventions.

Harding AJE, Morbey H, Ahmed F, Opdebeeck C, Lasrado R, Williamson PR, Swarbrick C, Leroi I, Challis D, Hellstrom I, Burns A, Keady J, Reilly ST.

BMC Geriatr. 2019 Mar 27;19(1):94. doi: 10.1186/s12877-019-1103-5.


Incorporating patients' perspectives into the initial stages of core outcome set development: a rapid review of qualitative studies of type 2 diabetes.

Gorst SL, Young B, Williamson PR, Wilding JPH, Harman NL.

BMJ Open Diabetes Res Care. 2019 Feb 28;7(1):e000615. doi: 10.1136/bmjdrc-2018-000615. eCollection 2019. Review.


The Pat1-Lsm complex prevents 3' to 5' degradation of a specific subset of ATG mRNAs during nitrogen starvation-induced autophagy.

Gatica D, Hu G, Zhang N, Williamson PR, Klionsky DJ.

Autophagy. 2019 Apr;15(4):750-751. doi: 10.1080/15548627.2019.1587262. Epub 2019 Mar 18.


A Multicenter, Longitudinal Cohort Study of Cryptococcosis in Human Immunodeficiency Virus-negative People in the United States.

Marr KA, Sun Y, Spec A, Lu N, Panackal A, Bennett J, Pappas P, Ostrander D, Datta K, Zhang SX, Williamson PR; Cryptococcus Infection Network Cohort Study Working Group .

Clin Infect Dis. 2020 Jan 2;70(2):252-261. doi: 10.1093/cid/ciz193.


Improving outcome reporting in clinical trial reports and protocols: study protocol for the Instrument for reporting Planned Endpoints in Clinical Trials (InsPECT).

Butcher NJ, Monsour A, Mew EJ, Szatmari P, Pierro A, Kelly LE, Farid-Kapadia M, Chee-A-Tow A, Saeed L, Monga S, Ungar W, Terwee CB, Vohra S, Fergusson D, Askie LM, Williamson PR, Chan AW, Moher D, Offringa M.

Trials. 2019 Mar 6;20(1):161. doi: 10.1186/s13063-019-3248-0.


Uptake of the OMERACT-OARSI Hip and Knee Osteoarthritis Core Outcome Set: Review of Randomized Controlled Trials from 1997 to 2017.

Smith TO, Mansfield M, Hawker GA, Hunter DJ, March LM, Boers M, Shea BJ, Christensen R, Guillemin F, Terwee CB, Williamson PR, Roos EM, Loeser RF, Schnitzer TJ, Kloppenburg M, Neogi T, Ladel CH, Kalsi G, Kaiser U, Buttel TW, Ashford AE, Mobasheri A, Arden NK, Tennant A, Hochberg MC, de Wit M, Tugwell P, Conaghan PG.

J Rheumatol. 2019 Aug;46(8):976-980. doi: 10.3899/jrheum.181066. Epub 2019 Mar 1.


Core Outcome Set-STAndardised Protocol Items: the COS-STAP Statement.

Kirkham JJ, Gorst S, Altman DG, Blazeby JM, Clarke M, Tunis S, Williamson PR; COS-STAP Group.

Trials. 2019 Feb 11;20(1):116. doi: 10.1186/s13063-019-3230-x.


The OMERACT-OARSI Core Domain Set for Measurement in Clinical Trials of Hip and/or Knee Osteoarthritis.

Smith TO, Hawker GA, Hunter DJ, March LM, Boers M, Shea BJ, Christensen R, Guillemin F, Terwee CB, Williamson PR, Dodd S, Roos EM, Loeser RF, Schnitzer TJ, Kloppenburg M, Neogi T, Ladel CH, Kalsi G, Kaiser U, Buttel TW, Ashford AE, Mobasheri A, Arden NK, Tennant A, Hochberg MC, de Wit M, Tugwell P, Conaghan PG.

J Rheumatol. 2019 Aug;46(8):981-989. doi: 10.3899/jrheum.181194. Epub 2019 Jan 15.


Short-term safety outcomes of mastectomy and immediate implant-based breast reconstruction with and without mesh (iBRA): a multicentre, prospective cohort study.

Potter S, Conroy EJ, Cutress RI, Williamson PR, Whisker L, Thrush S, Skillman J, Barnes NLP, Mylvaganam S, Teasdale E, Jain A, Gardiner MD, Blazeby JM, Holcombe C; iBRA Steering Group; Breast Reconstruction Research Collaborative.

Lancet Oncol. 2019 Feb;20(2):254-266. doi: 10.1016/S1470-2045(18)30781-2. Epub 2019 Jan 9.


Involving people living with dementia in research: an accessible modified Delphi survey for core outcome set development.

Morbey H, Harding AJE, Swarbrick C, Ahmed F, Elvish R, Keady J, Williamson PR, Reilly ST.

Trials. 2019 Jan 6;20(1):12. doi: 10.1186/s13063-018-3069-6.


Choosing important health outcomes for comparative effectiveness research: 4th annual update to a systematic review of core outcome sets for research.

Gargon E, Gorst SL, Harman NL, Smith V, Matvienko-Sikar K, Williamson PR.

PLoS One. 2018 Dec 28;13(12):e0209869. doi: 10.1371/journal.pone.0209869. eCollection 2018.


Cryptococcal meningitis is a cause for cross-reactivity in cerebrospinal fluid assays for anti-Histoplasma, anti-Coccidioides and anti-Blastomyces antibodies.

Bahr NC, Panackal AA, Durkin MM, Smedema ML, Keown W, Davis TE, Raymond-Guillen L, Park YD, Marr KA, Fries BC, Williamson PR, Boulware DR, Wheat LJ.

Mycoses. 2019 Mar;62(3):268-273. doi: 10.1111/myc.12882. Epub 2019 Jan 1.


Transcriptional Profiling of Patient Isolates Identifies a Novel TOR/Starvation Regulatory Pathway in Cryptococcal Virulence.

Park YD, Jarvis JN, Hu G, Davis SE, Qiu J, Zhang N, Hollingsworth C, Loyse A, Gardina PJ, Valyi-Nagy T, Myers TG, Harrison TS, Bicanic T, Williamson PR.

mBio. 2018 Dec 18;9(6). pii: e02353-18. doi: 10.1128/mBio.02353-18.


Higher number of items associated with significantly lower response rates in COS Delphi surveys.

Gargon E, Crew R, Burnside G, Williamson PR.

J Clin Epidemiol. 2019 Apr;108:110-120. doi: 10.1016/j.jclinepi.2018.12.010. Epub 2018 Dec 15.


The Pat1-Lsm Complex Stabilizes ATG mRNA during Nitrogen Starvation-Induced Autophagy.

Gatica D, Hu G, Liu X, Zhang N, Williamson PR, Klionsky DJ.

Mol Cell. 2019 Jan 17;73(2):314-324.e4. doi: 10.1016/j.molcel.2018.11.002. Epub 2018 Dec 6.


A core outcome set for clinical trials of chemoradiotherapy interventions for anal cancer (CORMAC): a patient and health-care professional consensus.

Fish R, Sanders C, Adams R, Brewer J, Brookes ST, DeNardo J, Kochhar R, Saunders MP, Sebag-Montefiore D, Williamson PR, Renehan AG.

Lancet Gastroenterol Hepatol. 2018 Dec;3(12):865-873. doi: 10.1016/S2468-1253(18)30264-4. Review.


Reducing attrition within clinical trials: The communication of retention and withdrawal within patient information leaflets.

Kearney A, Rosala-Hallas A, Bacon N, Daykin A, Shaw ARG, Lane AJ, Blazeby JM, Clarke M, Williamson PR, Gamble C.

PLoS One. 2018 Oct 31;13(10):e0204886. doi: 10.1371/journal.pone.0204886. eCollection 2018.


Reporting of outcomes in gastric cancer surgery trials: a systematic review.

Alkhaffaf B, Blazeby JM, Williamson PR, Bruce IA, Glenny AM.

BMJ Open. 2018 Oct 17;8(10):e021796. doi: 10.1136/bmjopen-2018-021796.


Cost-Effectiveness Analysis of Adalimumab for the Treatment of Uveitis Associated with Juvenile Idiopathic Arthritis.

Hughes DA, Culeddu G, Plumpton CO, Wood E, Dick AD, Jones AP, McKay A, Williamson PR, Compeyrot Lacassagne S, Hardwick B, Hickey H, Woo P, Beresford MW, Ramanan AV.

Ophthalmology. 2019 Mar;126(3):415-424. doi: 10.1016/j.ophtha.2018.09.043. Epub 2018 Oct 16.


Development of a standardised set of metrics for monitoring site performance in multicentre randomised trials: a Delphi study.

Whitham D, Turzanski J, Bradshaw L, Clarke M, Culliford L, Duley L, Shaw L, Skea Z, Treweek SP, Walker K, Williamson PR, Montgomery AA; Site Performance Metrics for Multicentre Randomised Trials Collaboration.

Trials. 2018 Oct 16;19(1):557. doi: 10.1186/s13063-018-2940-9.


"Real-Time" High-Throughput Drug and Synergy Testing for Multidrug-Resistant Bacterial Infection: A Case Report.

Sun W, Hesse S, Xu M, Childs RW, Zheng W, Williamson PR.

Front Med (Lausanne). 2018 Sep 20;5:267. doi: 10.3389/fmed.2018.00267. eCollection 2018.


Outcome reporting bias in trials: a methodological approach for assessment and adjustment in systematic reviews.

Kirkham JJ, Altman DG, Chan AW, Gamble C, Dwan KM, Williamson PR.

BMJ. 2018 Sep 28;362:k3802. doi: 10.1136/bmj.k3802. No abstract available.


Development of an online resource for recruitment research in clinical trials to organise and map current literature.

Kearney A, Harman NL, Rosala-Hallas A, Beecher C, Blazeby JM, Bower P, Clarke M, Cragg W, Duane S, Gardner H, Healy P, Maguire L, Mills N, Rooshenas L, Rowlands C, Treweek S, Vellinga A, Williamson PR, Gamble C.

Clin Trials. 2018 Dec;15(6):533-542. doi: 10.1177/1740774518796156. Epub 2018 Aug 31. Review.


Epigenetic Regulation of Autophagy: A Path to the Control of Autoimmunity.

Hargarten JC, Williamson PR.

Front Immunol. 2018 Aug 14;9:1864. doi: 10.3389/fimmu.2018.01864. eCollection 2018. Review.

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