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Items: 1 to 50 of 77

1.

Publisher Correction: Plasmodium falciparum sexual differentiation in malaria patients is associated with host factors and GDV1-dependent genes.

Usui M, Prajapati SK, Ayanful-Torgby R, Acquah FK, Cudjoe E, Kakaney C, Amponsah JA, Obboh EK, Reddy DK, Barbeau MC, Simons LM, Czesny B, Raiciulescu S, Olsen C, Abuaku BK, Amoah LE, Williamson KC.

Nat Commun. 2019 Jun 21;10(1):2740. doi: 10.1038/s41467-019-10805-w.

2.

Plasmodium falciparum sexual differentiation in malaria patients is associated with host factors and GDV1-dependent genes.

Usui M, Prajapati SK, Ayanful-Torgby R, Acquah FK, Cudjoe E, Kakaney C, Amponsah JA, Obboh EK, Reddy DK, Barbeau MC, Simons LM, Czesny B, Raiciulescu S, Olsen C, Abuaku BK, Amoah LE, Williamson KC.

Nat Commun. 2019 May 13;10(1):2140. doi: 10.1038/s41467-019-10172-6. Erratum in: Nat Commun. 2019 Jun 21;10(1):2740.

3.

Targeting Malaria in Flight.

Bargieri DY, Williamson KC.

Cell Host Microbe. 2019 May 8;25(5):631-632. doi: 10.1016/j.chom.2019.04.007.

PMID:
31071289
4.

Author Correction: The Plasmodium falciparum male gametocyte protein P230p, a paralog of P230, is vital for ookinete formation and mosquito transmission.

Marin-Mogollon C, van de Vegte-Bolmer M, van Gemert GJ, van Pul FJA, Ramesar J, Othman AS, Kroeze H, Miao J, Cui L, Williamson KC, Sauerwein RW, Janse CJ, Khan SM.

Sci Rep. 2019 May 3;9(1):7061. doi: 10.1038/s41598-019-43505-y.

5.

Transmission-Blocking Vaccines: Old Friends and New Prospects.

Acquah FK, Adjah J, Williamson KC, Amoah LE.

Infect Immun. 2019 May 21;87(6). pii: e00775-18. doi: 10.1128/IAI.00775-18. Print 2019 Jun. Review.

PMID:
30962400
6.

The Plasmodium falciparum male gametocyte protein P230p, a paralog of P230, is vital for ookinete formation and mosquito transmission.

Marin-Mogollon C, van de Vegte-Bolmer M, van Gemert GJ, van Pul FJA, Ramesar J, Othman AS, Kroeze H, Miao J, Cui L, Williamson KC, Sauerwein RW, Janse CJ, Khan SM.

Sci Rep. 2018 Oct 8;8(1):14902. doi: 10.1038/s41598-018-33236-x. Erratum in: Sci Rep. 2019 May 3;9(1):7061.

7.

The proteasome as a target to combat malaria: hits and misses.

Krishnan KM, Williamson KC.

Transl Res. 2018 Aug;198:40-47. doi: 10.1016/j.trsl.2018.04.007. Epub 2018 May 3. Review.

8.

Regulation of Sexual Commitment and Gametocytogenesis in Malaria Parasites.

Josling GA, Williamson KC, Llinás M.

Annu Rev Microbiol. 2018 Sep 8;72:501-519. doi: 10.1146/annurev-micro-090817-062712. Epub 2018 Jul 5. Review.

PMID:
29975590
9.

Seasonal variations in Plasmodium falciparum parasite prevalence assessed by varying diagnostic tests in asymptomatic children in southern Ghana.

Ayanful-Torgby R, Quashie NB, Boampong JN, Williamson KC, Amoah LE.

PLoS One. 2018 Jun 15;13(6):e0199172. doi: 10.1371/journal.pone.0199172. eCollection 2018.

10.

Gametocyte Development and Carriage in Ghanaian Individuals with Uncomplicated Plasmodium falciparum Malaria.

Dinko B, Ansah F, Agyare-Kwabi C, Tagboto S, Amoah LE, Urban BC, Sutherland CJ, Awandare GA, Williamson KC, Binka FN, Deitsch KW.

Am J Trop Med Hyg. 2018 Jul;99(1):57-64. doi: 10.4269/ajtmh.18-0077. Epub 2018 Apr 19.

11.

Even malaria parasites watch their host's diet.

Williamson KC, Levine RL, Miller LH.

Nat Microbiol. 2018 Feb;3(2):130-131. doi: 10.1038/s41564-017-0105-3. No abstract available.

12.

Incidence and risk factors of bacterial and fungal infection during induction chemotherapy for high-risk neuroblastoma.

Whittle SB, Williamson KC, Russell HV.

Pediatr Hematol Oncol. 2017 Aug;34(5):331-342. doi: 10.1080/08880018.2017.1396386. Epub 2017 Dec 4.

PMID:
29200325
13.

Efficient Synthesis of 1,9-Substituted Benzo[h][1,6]naphthyridin-2(1H)-ones and Evaluation of their Plasmodium falciparum Gametocytocidal Activities.

Li H, Sun W, Huang X, Lu X, Patel PR, Kim M, Orr MJ, Fisher RM, Tanaka TQ, McKew JC, Simeonov A, Sanderson PE, Zheng W, Williamson KC, Huang W.

ACS Comb Sci. 2017 Dec 11;19(12):748-754. doi: 10.1021/acscombsci.7b00119. Epub 2017 Oct 27.

14.

Natural antibody responses to Plasmodium falciparum MSP3 and GLURP(R0) antigens are associated with low parasite densities in malaria patients living in the Central Region of Ghana.

Amoah LE, Nuvor SV, Obboh EK, Acquah FK, Asare K, Singh SK, Boampong JN, Theisen M, Williamson KC.

Parasit Vectors. 2017 Aug 23;10(1):395. doi: 10.1186/s13071-017-2338-7.

15.

MEPicides: potent antimalarial prodrugs targeting isoprenoid biosynthesis.

Edwards RL, Brothers RC, Wang X, Maron MI, Ziniel PD, Tsang PS, Kraft TE, Hruz PW, Williamson KC, Dowd CS, John ARO.

Sci Rep. 2017 Aug 21;7(1):8400. doi: 10.1038/s41598-017-07159-y.

16.

Antibody responses to two new Lactococcus lactis-produced recombinant Pfs48/45 and Pfs230 proteins increase with age in malaria patients living in the Central Region of Ghana.

Acquah FK, Obboh EK, Asare K, Boampong JN, Nuvor SV, Singh SK, Theisen M, Williamson KC, Amoah LE.

Malar J. 2017 Aug 1;16(1):306. doi: 10.1186/s12936-017-1955-0.

17.

New adenovirus-based vaccine vectors targeting Pfs25 elicit antibodies that inhibit Plasmodium falciparum transmission.

McGuire KA, Miura K, Wiethoff CM, Williamson KC.

Malar J. 2017 Jun 15;16(1):254. doi: 10.1186/s12936-017-1896-7.

18.

Novel lead structures with both Plasmodium falciparum gametocytocidal and asexual blood stage activity identified from high throughput compound screening.

Sun W, Huang X, Li H, Tawa G, Fisher E, Tanaka TQ, Shinn P, Huang W, Williamson KC, Zheng W.

Malar J. 2017 Apr 13;16(1):147. doi: 10.1186/s12936-017-1805-0.

19.

Plasmodium falciparum genotype and gametocyte prevalence in children with uncomplicated malaria in coastal Ghana.

Ayanful-Torgby R, Oppong A, Abankwa J, Acquah F, Williamson KC, Amoah LE.

Malar J. 2016 Dec 9;15(1):592.

20.

In vitro evaluation of imidazo[4,5-c]quinolin-2-ones as gametocytocidal antimalarial agents.

Patel PR, Sun W, Kim M, Huang X, Sanderson PE, Tanaka TQ, McKew JC, Simeonov A, Williamson KC, Zheng W, Huang W.

Bioorg Med Chem Lett. 2016 Jun 15;26(12):2907-2911. doi: 10.1016/j.bmcl.2016.04.045. Epub 2016 Apr 19.

21.

Fighting the Monster: Applying the Host Damage Framework to Human Central Nervous System Infections.

Panackal AA, Williamson KC, van de Beek D, Boulware DR, Williamson PR.

MBio. 2016 Jan 26;7(1):e01906-15. doi: 10.1128/mBio.01906-15. Review.

22.

Maduramicin Rapidly Eliminates Malaria Parasites and Potentiates the Gametocytocidal Activity of the Pyrazoleamide PA21A050.

Maron MI, Magle CT, Czesny B, Turturice BA, Huang R, Zheng W, Vaidya AB, Williamson KC.

Antimicrob Agents Chemother. 2015 Dec 28;60(3):1492-9. doi: 10.1128/AAC.01928-15.

23.

CNS infections in 2015: emerging catastrophic infections and new insights into neuroimmunological host damage.

Williamson PR, Nash TE, Williamson KC, Nath A.

Lancet Neurol. 2016 Jan;15(1):17-9. doi: 10.1016/S1474-4422(15)00359-2. Epub 2015 Dec 8. Review. No abstract available.

24.

Adhesion protein complexes of malaria gametocytes assemble following parasite transmission to the mosquito.

Simon N, Kuehn A, Williamson KC, Pradel G.

Parasitol Int. 2016 Feb;65(1):27-30. doi: 10.1016/j.parint.2015.09.007. Epub 2015 Sep 25. No abstract available.

25.

Plasmodium falciparum Gametocyte-Specific Antibody Profiling Reveals Boosting through Natural Infection and Identifies Potential Markers of Gametocyte Exposure.

Skinner J, Huang CY, Waisberg M, Felgner PL, Doumbo OK, Ongoiba A, Kayentao K, Traore B, Crompton PD, Williamson KC.

Infect Immun. 2015 Nov;83(11):4229-36. doi: 10.1128/IAI.00644-15. Epub 2015 Aug 17.

26.

Potent Plasmodium falciparum gametocytocidal activity of diaminonaphthoquinones, lead antimalarial chemotypes identified in an antimalarial compound screen.

Tanaka TQ, Guiguemde WA, Barnett DS, Maron MI, Min J, Connelly MC, Suryadevara PK, Guy RK, Williamson KC.

Antimicrob Agents Chemother. 2015 Mar;59(3):1389-97. doi: 10.1128/AAC.01930-13. Epub 2014 Dec 15.

27.

The effect of citrulline and arginine supplementation on lactic acidemia in MELAS syndrome.

El-Hattab AW, Emrick LT, Williamson KC, Craigen WJ, Scaglia F.

Meta Gene. 2013 Oct 15;1:8-14. doi: 10.1016/j.mgene.2013.09.001. eCollection 2013 Dec.

28.

Plasmodium falciparum transmission stages accumulate in the human bone marrow.

Joice R, Nilsson SK, Montgomery J, Dankwa S, Egan E, Morahan B, Seydel KB, Bertuccini L, Alano P, Williamson KC, Duraisingh MT, Taylor TE, Milner DA, Marti M.

Sci Transl Med. 2014 Jul 9;6(244):244re5. doi: 10.1126/scitranslmed.3008882.

29.

A rapid sensitive, flow cytometry-based method for the detection of Plasmodium vivax-infected blood cells.

Roobsoong W, Maher SP, Rachaphaew N, Barnes SJ, Williamson KC, Sattabongkot J, Adams JH.

Malar J. 2014 Feb 14;13:55. doi: 10.1186/1475-2875-13-55.

30.

Chemical signatures and new drug targets for gametocytocidal drug development.

Sun W, Tanaka TQ, Magle CT, Huang W, Southall N, Huang R, Dehdashti SJ, McKew JC, Williamson KC, Zheng W.

Sci Rep. 2014 Jan 17;4:3743. doi: 10.1038/srep03743.

31.

Type II fatty acid biosynthesis is essential for Plasmodium falciparum sporozoite development in the midgut of Anopheles mosquitoes.

van Schaijk BC, Kumar TR, Vos MW, Richman A, van Gemert GJ, Li T, Eappen AG, Williamson KC, Morahan BJ, Fishbaugher M, Kennedy M, Camargo N, Khan SM, Janse CJ, Sim KL, Hoffman SL, Kappe SH, Sauerwein RW, Fidock DA, Vaughan AM.

Eukaryot Cell. 2014 May;13(5):550-9. doi: 10.1128/EC.00264-13. Epub 2013 Dec 2.

32.

Plasmodium dipeptidyl aminopeptidases as malaria transmission-blocking drug targets.

Tanaka TQ, Deu E, Molina-Cruz A, Ashburne MJ, Ali O, Suri A, Kortagere S, Bogyo M, Williamson KC.

Antimicrob Agents Chemother. 2013 Oct;57(10):4645-52. doi: 10.1128/AAC.02495-12. Epub 2013 Jul 8.

33.

Host immune constraints on malaria transmission: insights from population biology of within-host parasites.

McQueen PG, Williamson KC, McKenzie FE.

Malar J. 2013 Jun 15;12:206. doi: 10.1186/1475-2875-12-206.

34.

Transposon mutagenesis identifies genes essential for Plasmodium falciparum gametocytogenesis.

Ikadai H, Shaw Saliba K, Kanzok SM, McLean KJ, Tanaka TQ, Cao J, Williamson KC, Jacobs-Lorena M.

Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):E1676-84. doi: 10.1073/pnas.1217712110. Epub 2013 Apr 9.

35.

HIV treatments have malaria gametocyte killing and transmission blocking activity.

Hobbs CV, Tanaka TQ, Muratova O, Van Vliet J, Borkowsky W, Williamson KC, Duffy PE.

J Infect Dis. 2013 Jul;208(1):139-48. doi: 10.1093/infdis/jit132. Epub 2013 Mar 28.

36.

A quantitative high throughput assay for identifying gametocytocidal compounds.

Tanaka TQ, Dehdashti SJ, Nguyen DT, McKew JC, Zheng W, Williamson KC.

Mol Biochem Parasitol. 2013 Mar;188(1):20-5. doi: 10.1016/j.molbiopara.2013.02.005. Epub 2013 Feb 27.

37.

When do spatial abilities support student comprehension of STEM visualizations?

Hinze SR, Williamson VM, Shultz MJ, Williamson KC, Deslongchamps G, Rapp DN.

Cogn Process. 2013 May;14(2):129-42. doi: 10.1007/s10339-013-0539-3. Epub 2013 Feb 5.

PMID:
23381193
38.

Validation of the proteasome as a therapeutic target in Plasmodium using an epoxyketone inhibitor with parasite-specific toxicity.

Li H, Ponder EL, Verdoes M, Asbjornsdottir KH, Deu E, Edgington LE, Lee JT, Kirk CJ, Demo SD, Williamson KC, Bogyo M.

Chem Biol. 2012 Dec 21;19(12):1535-45. doi: 10.1016/j.chembiol.2012.09.019. Epub 2012 Nov 8.

39.

A class of tricyclic compounds blocking malaria parasite oocyst development and transmission.

Eastman RT, Pattaradilokrat S, Raj DK, Dixit S, Deng B, Miura K, Yuan J, Tanaka TQ, Johnson RL, Jiang H, Huang R, Williamson KC, Lambert LE, Long C, Austin CP, Wu Y, Su XZ.

Antimicrob Agents Chemother. 2013 Jan;57(1):425-35. doi: 10.1128/AAC.00920-12. Epub 2012 Nov 5.

40.

Plasmodium falciparum gametocyte development 1 (Pfgdv1) and gametocytogenesis early gene identification and commitment to sexual development.

Eksi S, Morahan BJ, Haile Y, Furuya T, Jiang H, Ali O, Xu H, Kiattibutr K, Suri A, Czesny B, Adeyemo A, Myers TG, Sattabongkot J, Su XZ, Williamson KC.

PLoS Pathog. 2012;8(10):e1002964. doi: 10.1371/journal.ppat.1002964. Epub 2012 Oct 18.

41.

Directional gene expression and antisense transcripts in sexual and asexual stages of Plasmodium falciparum.

López-Barragán MJ, Lemieux J, Quiñones M, Williamson KC, Molina-Cruz A, Cui K, Barillas-Mury C, Zhao K, Su XZ.

BMC Genomics. 2011 Nov 30;12:587. doi: 10.1186/1471-2164-12-587.

42.

Functional analysis of the exported type IV HSP40 protein PfGECO in Plasmodium falciparum gametocytes.

Morahan BJ, Strobel C, Hasan U, Czesny B, Mantel PY, Marti M, Eksi S, Williamson KC.

Eukaryot Cell. 2011 Nov;10(11):1492-503. doi: 10.1128/EC.05155-11. Epub 2011 Sep 30.

43.

A high-throughput screen targeting malaria transmission stages opens new avenues for drug development.

Buchholz K, Burke TA, Williamson KC, Wiegand RC, Wirth DF, Marti M.

J Infect Dis. 2011 May 15;203(10):1445-53. doi: 10.1093/infdis/jir037.

44.

Protein targeting to the parasitophorous vacuole membrane of Plasmodium falciparum.

Eksi S, Williamson KC.

Eukaryot Cell. 2011 Jun;10(6):744-52. doi: 10.1128/EC.00008-11. Epub 2011 Apr 15.

45.

A malaria gametocytocidal assay using oxidoreduction indicator, alamarBlue.

Tanaka TQ, Williamson KC.

Mol Biochem Parasitol. 2011 Jun;177(2):160-3. doi: 10.1016/j.molbiopara.2011.02.005. Epub 2011 Feb 18.

46.

Malaria parasites form filamentous cell-to-cell connections during reproduction in the mosquito midgut.

Rupp I, Sologub L, Williamson KC, Scheuermayer M, Reininger L, Doerig C, Eksi S, Kombila DU, Frank M, Pradel G.

Cell Res. 2011 Apr;21(4):683-96. doi: 10.1038/cr.2010.176. Epub 2010 Dec 21.

47.

The proteasome inhibitor epoxomicin has potent Plasmodium falciparum gametocytocidal activity.

Czesny B, Goshu S, Cook JL, Williamson KC.

Antimicrob Agents Chemother. 2009 Oct;53(10):4080-5. doi: 10.1128/AAC.00088-09. Epub 2009 Aug 3.

48.

Approaches to malaria vaccine development using the retrospectroscope.

Sardá V, Kaslow DC, Williamson KC.

Infect Immun. 2009 Aug;77(8):3130-40. doi: 10.1128/IAI.00122-09. Epub 2009 May 18. Review. No abstract available.

49.

Sex- and stage-specific reporter gene expression in Plasmodium falciparum.

Eksi S, Suri A, Williamson KC.

Mol Biochem Parasitol. 2008 Aug;160(2):148-51. doi: 10.1016/j.molbiopara.2008.04.005. Epub 2008 Apr 14.

50.

Inhibition of Plasmodium falciparum oocyst production by membrane-permeant cysteine protease inhibitor E64d.

Eksi S, Czesny B, van Gemert GJ, Sauerwein RW, Eling W, Williamson KC.

Antimicrob Agents Chemother. 2007 Mar;51(3):1064-70. Epub 2006 Dec 18.

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