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Items: 1 to 50 of 68

1.

A DNA nick at Ku-blocked double-strand break ends serves as an entry site for exonuclease 1 (Exo1) or Sgs1-Dna2 in long-range DNA end resection.

Wang W, Daley JM, Kwon Y, Xue X, Krasner DS, Miller AS, Nguyen KA, Williamson EA, Shim EY, Lee SE, Hromas R, Sung P.

J Biol Chem. 2018 Nov 2;293(44):17061-17069. doi: 10.1074/jbc.RA118.004769. Epub 2018 Sep 17.

PMID:
30224356
2.

Primates in peril: the significance of Brazil, Madagascar, Indonesia and the Democratic Republic of the Congo for global primate conservation.

Estrada A, Garber PA, Mittermeier RA, Wich S, Gouveia S, Dobrovolski R, Nekaris KAI, Nijman V, Rylands AB, Maisels F, Williamson EA, Bicca-Marques J, Fuentes A, Jerusalinsky L, Johnson S, Rodrigues de Melo F, Oliveira L, Schwitzer C, Roos C, Cheyne SM, Martins Kierulff MC, Raharivololona B, Talebi M, Ratsimbazafy J, Supriatna J, Boonratana R, Wedana M, Setiawan A.

PeerJ. 2018 Jun 15;6:e4869. doi: 10.7717/peerj.4869. eCollection 2018.

3.

The Wave2 scaffold Hem-1 is required for transition of fetal liver hematopoiesis to bone marrow.

Shao L, Chang J, Feng W, Wang X, Williamson EA, Li Y, Schajnovitz A, Scadden D, Mortensen LJ, Lin CP, Li L, Paulson A, Downing J, Zhou D, Hromas RA.

Nat Commun. 2018 Jun 18;9(1):2377. doi: 10.1038/s41467-018-04716-5.

4.

Guns, germs, and trees determine density and distribution of gorillas and chimpanzees in Western Equatorial Africa.

Strindberg S, Maisels F, Williamson EA, Blake S, Stokes EJ, Aba'a R, Abitsi G, Agbor A, Ambahe RD, Bakabana PC, Bechem M, Berlemont A, Bokoto de Semboli B, Boundja PR, Bout N, Breuer T, Campbell G, De Wachter P, Ella Akou M, Esono Mba F, Feistner ATC, Fosso B, Fotso R, Greer D, Inkamba-Nkulu C, Iyenguet CF, Jeffery KJ, Kokangoye M, Kühl HS, Latour S, Madzoke B, Makoumbou C, Malanda GF, Malonga R, Mbolo V, Morgan DB, Motsaba P, Moukala G, Mowawa BS, Murai M, Ndzai C, Nishihara T, Nzooh Z, Pintea L, Pokempner A, Rainey HJ, Rayden T, Ruffler H, Sanz CM, Todd A, Vanleeuwe H, Vosper A, Warren Y, Wilkie DS.

Sci Adv. 2018 Apr 25;4(4):eaar2964. doi: 10.1126/sciadv.aar2964. eCollection 2018 Apr.

5.

Synthetic lethality in malignant pleural mesothelioma with PARP1 inhibition.

Srinivasan G, Sidhu GS, Williamson EA, Jaiswal AS, Najmunnisa N, Wilcoxen K, Jones D, George TJ Jr, Hromas R.

Cancer Chemother Pharmacol. 2017 Oct;80(4):861-867. doi: 10.1007/s00280-017-3401-y. Epub 2017 Jul 29.

6.

The Critically Endangered western chimpanzee declines by 80.

Kühl HS, Sop T, Williamson EA, Mundry R, Brugière D, Campbell G, Cohen H, Danquah E, Ginn L, Herbinger I, Jones S, Junker J, Kormos R, Kouakou CY, N'Goran PK, Normand E, Shutt-Phillips K, Tickle A, Vendras E, Welsh A, Wessling EG, Boesch C.

Am J Primatol. 2017 Sep;79(9). doi: 10.1002/ajp.22681. Epub 2017 Jul 3.

PMID:
28671715
7.

Drugging the Cancers Addicted to DNA Repair.

Nickoloff JA, Jones D, Lee SH, Williamson EA, Hromas R.

J Natl Cancer Inst. 2017 Nov 1;109(11). doi: 10.1093/jnci/djx059. Review.

8.

Endonuclease EEPD1 Is a Gatekeeper for Repair of Stressed Replication Forks.

Kim HS, Nickoloff JA, Wu Y, Williamson EA, Sidhu GS, Reinert BL, Jaiswal AS, Srinivasan G, Patel B, Kong K, Burma S, Lee SH, Hromas RA.

J Biol Chem. 2017 Feb 17;292(7):2795-2804. doi: 10.1074/jbc.M116.758235. Epub 2017 Jan 3.

9.

Metnase Mediates Loading of Exonuclease 1 onto Single Strand Overhang DNA for End Resection at Stalled Replication Forks.

Kim HS, Williamson EA, Nickoloff JA, Hromas RA, Lee SH.

J Biol Chem. 2017 Jan 27;292(4):1414-1425. doi: 10.1074/jbc.M116.745646. Epub 2016 Dec 14.

10.

Catastrophic Decline of World's Largest Primate: 80% Loss of Grauer's Gorilla (Gorilla beringei graueri) Population Justifies Critically Endangered Status.

Plumptre AJ, Nixon S, Kujirakwinja DK, Vieilledent G, Critchlow R, Williamson EA, Nishuli R, Kirkby AE, Hall JS.

PLoS One. 2016 Oct 19;11(10):e0162697. doi: 10.1371/journal.pone.0162697. eCollection 2016.

11.

A rare form of Hansen's disease presenting as filiform verrucous papules on the feet.

Richard EB, Williamson EA, Jackson SM, Stryjewska BM.

JAAD Case Rep. 2016 Mar 3;2(2):105-7. doi: 10.1016/j.jdcr.2015.11.015. eCollection 2016 Mar. No abstract available.

12.

The homologous recombination component EEPD1 is required for genome stability in response to developmental stress of vertebrate embryogenesis.

Chun C, Wu Y, Lee SH, Williamson EA, Reinert BL, Jaiswal AS, Nickoloff JA, Hromas RA.

Cell Cycle. 2016;15(7):957-62. doi: 10.1080/15384101.2016.1151585.

13.

EEPD1 Rescues Stressed Replication Forks and Maintains Genome Stability by Promoting End Resection and Homologous Recombination Repair.

Wu Y, Lee SH, Williamson EA, Reinert BL, Cho JH, Xia F, Jaiswal AS, Srinivasan G, Patel B, Brantley A, Zhou D, Shao L, Pathak R, Hauer-Jensen M, Singh S, Kong K, Wu X, Kim HS, Beissbarth T, Gaedcke J, Burma S, Nickoloff JA, Hromas RA.

PLoS Genet. 2015 Dec 18;11(12):e1005675. doi: 10.1371/journal.pgen.1005675. eCollection 2015 Dec.

14.

Apes in the Anthropocene: flexibility and survival.

Hockings KJ, McLennan MR, Carvalho S, Ancrenaz M, Bobe R, Byrne RW, Dunbar RI, Matsuzawa T, McGrew WC, Williamson EA, Wilson ML, Wood B, Wrangham RW, Hill CM.

Trends Ecol Evol. 2015 Apr;30(4):215-22. doi: 10.1016/j.tree.2015.02.002. Epub 2015 Mar 9. Review.

PMID:
25766059
15.

Great apes and biodiversity offset projects in Africa: the case for national offset strategies.

Kormos R, Kormos CF, Humle T, Lanjouw A, Rainer H, Victurine R, Mittermeier RA, Diallo MS, Rylands AB, Williamson EA.

PLoS One. 2014 Nov 5;9(11):e111671. doi: 10.1371/journal.pone.0111671. eCollection 2014.

16.

The DNA repair component Metnase regulates Chk1 stability.

Williamson EA, Wu Y, Singh S, Byrne M, Wray J, Lee SH, Nickoloff JA, Hromas R.

Cell Div. 2014 Jul 9;9:1. doi: 10.1186/1747-1028-9-1. eCollection 2014.

17.

Repressing DNA repair to enhance chemotherapy: targeting MyD88 in colon cancer.

Williamson EA, Hromas R.

J Natl Cancer Inst. 2013 Jul 3;105(13):926-7. doi: 10.1093/jnci/djt148. Epub 2013 Jun 13. No abstract available.

18.

PARP1 is required for chromosomal translocations.

Wray J, Williamson EA, Singh SB, Wu Y, Cogle CR, Weinstock DM, Zhang Y, Lee SH, Zhou D, Shao L, Hauer-Jensen M, Pathak R, Klimek V, Nickoloff JA, Hromas R.

Blood. 2013 May 23;121(21):4359-65. doi: 10.1182/blood-2012-10-460527. Epub 2013 Apr 8.

19.

Devastating decline of forest elephants in central Africa.

Maisels F, Strindberg S, Blake S, Wittemyer G, Hart J, Williamson EA, Aba'a R, Abitsi G, Ambahe RD, Amsini F, Bakabana PC, Hicks TC, Bayogo RE, Bechem M, Beyers RL, Bezangoye AN, Boundja P, Bout N, Akou ME, Bene LB, Fosso B, Greengrass E, Grossmann F, Ikamba-Nkulu C, Ilambu O, Inogwabini BI, Iyenguet F, Kiminou F, Kokangoye M, Kujirakwinja D, Latour S, Liengola I, Mackaya Q, Madidi J, Madzoke B, Makoumbou C, Malanda GA, Malonga R, Mbani O, Mbendzo VA, Ambassa E, Ekinde A, Mihindou Y, Morgan BJ, Motsaba P, Moukala G, Mounguengui A, Mowawa BS, Ndzai C, Nixon S, Nkumu P, Nzolani F, Pintea L, Plumptre A, Rainey H, de Semboli BB, Serckx A, Stokes E, Turkalo A, Vanleeuwe H, Vosper A, Warren Y.

PLoS One. 2013;8(3):e59469. doi: 10.1371/journal.pone.0059469. Epub 2013 Mar 4.

20.

Targeting the transposase domain of the DNA repair component Metnase to enhance chemotherapy.

Williamson EA, Damiani L, Leitao A, Hu C, Hathaway H, Oprea T, Sklar L, Shaheen M, Bauman J, Wang W, Nickoloff JA, Lee SH, Hromas R.

Cancer Res. 2012 Dec 1;72(23):6200-8. doi: 10.1158/0008-5472.CAN-12-0313. Epub 2012 Oct 22.

21.

A role for hippocampal actin rearrangement in object placement memory in female rats.

Nelson BS, Witty CF, Williamson EA, Daniel JM.

Neurobiol Learn Mem. 2012 Oct;98(3):284-90. doi: 10.1016/j.nlm.2012.09.006. Epub 2012 Sep 22.

PMID:
23010136
22.

Overview for the histone codes for DNA repair.

Williamson EA, Wray JW, Bansal P, Hromas R.

Prog Mol Biol Transl Sci. 2012;110:207-27. doi: 10.1016/B978-0-12-387665-2.00008-0. Review.

23.

Chk1 phosphorylation of Metnase enhances DNA repair but inhibits replication fork restart.

Hromas R, Williamson EA, Fnu S, Lee YJ, Park SJ, Beck BD, You JS, Leitao A, Nickoloff JA, Lee SH.

Oncogene. 2012 Sep 20;31(38):4245-54. doi: 10.1038/onc.2011.586. Epub 2012 Jan 9. Erratum in: Oncogene. 2014 Jan 23;33(4):536. Laitao, A [corrected to Leitao, A].

24.

Methylation of histone H3 lysine 36 enhances DNA repair by nonhomologous end-joining.

Fnu S, Williamson EA, De Haro LP, Brenneman M, Wray J, Shaheen M, Radhakrishnan K, Lee SH, Nickoloff JA, Hromas R.

Proc Natl Acad Sci U S A. 2011 Jan 11;108(2):540-5. doi: 10.1073/pnas.1013571108. Epub 2010 Dec 27.

25.

The impact of conservation on the status of the world's vertebrates.

Hoffmann M, Hilton-Taylor C, Angulo A, Böhm M, Brooks TM, Butchart SH, Carpenter KE, Chanson J, Collen B, Cox NA, Darwall WR, Dulvy NK, Harrison LR, Katariya V, Pollock CM, Quader S, Richman NI, Rodrigues AS, Tognelli MF, Vié JC, Aguiar JM, Allen DJ, Allen GR, Amori G, Ananjeva NB, Andreone F, Andrew P, Aquino Ortiz AL, Baillie JE, Baldi R, Bell BD, Biju SD, Bird JP, Black-Decima P, Blanc JJ, Bolaños F, Bolivar-G W, Burfield IJ, Burton JA, Capper DR, Castro F, Catullo G, Cavanagh RD, Channing A, Chao NL, Chenery AM, Chiozza F, Clausnitzer V, Collar NJ, Collett LC, Collette BB, Cortez Fernandez CF, Craig MT, Crosby MJ, Cumberlidge N, Cuttelod A, Derocher AE, Diesmos AC, Donaldson JS, Duckworth JW, Dutson G, Dutta SK, Emslie RH, Farjon A, Fowler S, Freyhof J, Garshelis DL, Gerlach J, Gower DJ, Grant TD, Hammerson GA, Harris RB, Heaney LR, Hedges SB, Hero JM, Hughes B, Hussain SA, Icochea M J, Inger RF, Ishii N, Iskandar DT, Jenkins RK, Kaneko Y, Kottelat M, Kovacs KM, Kuzmin SL, La Marca E, Lamoreux JF, Lau MW, Lavilla EO, Leus K, Lewison RL, Lichtenstein G, Livingstone SR, Lukoschek V, Mallon DP, McGowan PJ, McIvor A, Moehlman PD, Molur S, Muñoz Alonso A, Musick JA, Nowell K, Nussbaum RA, Olech W, Orlov NL, Papenfuss TJ, Parra-Olea G, Perrin WF, Polidoro BA, Pourkazemi M, Racey PA, Ragle JS, Ram M, Rathbun G, Reynolds RP, Rhodin AG, Richards SJ, Rodríguez LO, Ron SR, Rondinini C, Rylands AB, Sadovy de Mitcheson Y, Sanciangco JC, Sanders KL, Santos-Barrera G, Schipper J, Self-Sullivan C, Shi Y, Shoemaker A, Short FT, Sillero-Zubiri C, Silvano DL, Smith KG, Smith AT, Snoeks J, Stattersfield AJ, Symes AJ, Taber AB, Talukdar BK, Temple HJ, Timmins R, Tobias JA, Tsytsulina K, Tweddle D, Ubeda C, Valenti SV, van Dijk PP, Veiga LM, Veloso A, Wege DC, Wilkinson M, Williamson EA, Xie F, Young BE, Akçakaya HR, Bennun L, Blackburn TM, Boitani L, Dublin HT, da Fonseca GA, Gascon C, Lacher TE Jr, Mace GM, Mainka SA, McNeely JA, Mittermeier RA, Reid GM, Rodriguez JP, Rosenberg AA, Samways MJ, Smart J, Stein BA, Stuart SN.

Science. 2010 Dec 10;330(6010):1503-9. doi: 10.1126/science.1194442. Epub 2010 Oct 26.

26.

Cytotoxic activity of the titanium alkoxide (OPy)(2)Ti(4AP)(2) against cancer colony forming cells.

Williamson EA, Boyle TJ, Raymond R, Farrington J, Verschraegen C, Shaheen M, Hromas R.

Invest New Drugs. 2012 Feb;30(1):114-20. doi: 10.1007/s10637-010-9530-3. Epub 2010 Sep 7.

27.

The transposase domain protein Metnase/SETMAR suppresses chromosomal translocations.

Wray J, Williamson EA, Chester S, Farrington J, Sterk R, Weinstock DM, Jasin M, Lee SH, Nickoloff JA, Hromas R.

Cancer Genet Cytogenet. 2010 Jul 15;200(2):184-90. doi: 10.1016/j.cancergencyto.2010.04.011.

28.

Metnase promotes restart and repair of stalled and collapsed replication forks.

De Haro LP, Wray J, Williamson EA, Durant ST, Corwin L, Gentry AC, Osheroff N, Lee SH, Hromas R, Nickoloff JA.

Nucleic Acids Res. 2010 Sep;38(17):5681-91. doi: 10.1093/nar/gkq339. Epub 2010 May 10.

29.

Metnase mediates chromosome decatenation in acute leukemia cells.

Wray J, Williamson EA, Sheema S, Lee SH, Libby E, Willman CL, Nickoloff JA, Hromas R.

Blood. 2009 Aug 27;114(9):1852-8. doi: 10.1182/blood-2008-08-175760. Epub 2009 May 20.

30.

Metnase mediates resistance to topoisomerase II inhibitors in breast cancer cells.

Wray J, Williamson EA, Royce M, Shaheen M, Beck BD, Lee SH, Nickoloff JA, Hromas R.

PLoS One. 2009;4(4):e5323. doi: 10.1371/journal.pone.0005323. Epub 2009 Apr 24.

31.

Expression of Scl in mesoderm rescues hematopoiesis in the absence of Oct-4.

Kong KY, Williamson EA, Rogers JH, Tran T, Hromas R, Dahl R.

Blood. 2009 Jul 2;114(1):60-3. doi: 10.1182/blood-2008-08-174755. Epub 2009 Mar 25.

32.

The status of the world's land and marine mammals: diversity, threat, and knowledge.

Schipper J, Chanson JS, Chiozza F, Cox NA, Hoffmann M, Katariya V, Lamoreux J, Rodrigues AS, Stuart SN, Temple HJ, Baillie J, Boitani L, Lacher TE Jr, Mittermeier RA, Smith AT, Absolon D, Aguiar JM, Amori G, Bakkour N, Baldi R, Berridge RJ, Bielby J, Black PA, Blanc JJ, Brooks TM, Burton JA, Butynski TM, Catullo G, Chapman R, Cokeliss Z, Collen B, Conroy J, Cooke JG, da Fonseca GA, Derocher AE, Dublin HT, Duckworth JW, Emmons L, Emslie RH, Festa-Bianchet M, Foster M, Foster S, Garshelis DL, Gates C, Gimenez-Dixon M, Gonzalez S, Gonzalez-Maya JF, Good TC, Hammerson G, Hammond PS, Happold D, Happold M, Hare J, Harris RB, Hawkins CE, Haywood M, Heaney LR, Hedges S, Helgen KM, Hilton-Taylor C, Hussain SA, Ishii N, Jefferson TA, Jenkins RK, Johnston CH, Keith M, Kingdon J, Knox DH, Kovacs KM, Langhammer P, Leus K, Lewison R, Lichtenstein G, Lowry LF, Macavoy Z, Mace GM, Mallon DP, Masi M, McKnight MW, Medellín RA, Medici P, Mills G, Moehlman PD, Molur S, Mora A, Nowell K, Oates JF, Olech W, Oliver WR, Oprea M, Patterson BD, Perrin WF, Polidoro BA, Pollock C, Powel A, Protas Y, Racey P, Ragle J, Ramani P, Rathbun G, Reeves RR, Reilly SB, Reynolds JE 3rd, Rondinini C, Rosell-Ambal RG, Rulli M, Rylands AB, Savini S, Schank CJ, Sechrest W, Self-Sullivan C, Shoemaker A, Sillero-Zubiri C, De Silva N, Smith DE, Srinivasulu C, Stephenson PJ, van Strien N, Talukdar BK, Taylor BL, Timmins R, Tirira DG, Tognelli MF, Tsytsulina K, Veiga LM, Vié JC, Williamson EA, Wyatt SA, Xie Y, Young BE.

Science. 2008 Oct 10;322(5899):225-30. doi: 10.1126/science.1165115.

33.

The SET and transposase domain protein Metnase enhances chromosome decatenation: regulation by automethylation.

Williamson EA, Rasila KK, Corwin LK, Wray J, Beck BD, Severns V, Mobarak C, Lee SH, Nickoloff JA, Hromas R.

Nucleic Acids Res. 2008 Oct;36(18):5822-31. doi: 10.1093/nar/gkn560. Epub 2008 Sep 12.

34.

The human set and transposase domain protein Metnase interacts with DNA Ligase IV and enhances the efficiency and accuracy of non-homologous end-joining.

Hromas R, Wray J, Lee SH, Martinez L, Farrington J, Corwin LK, Ramsey H, Nickoloff JA, Williamson EA.

DNA Repair (Amst). 2008 Dec 1;7(12):1927-37. doi: 10.1016/j.dnarep.2008.08.002. Epub 2008 Sep 18.

35.

Expression levels of the human DNA repair protein metnase influence lentiviral genomic integration.

Williamson EA, Farrington J, Martinez L, Ness S, O'Rourke J, Lee SH, Nickoloff J, Hromas R.

Biochimie. 2008 Sep;90(9):1422-6. doi: 10.1016/j.biochi.2008.05.010. Epub 2008 May 23.

36.

Unmasking of epigenetically silenced genes reveals DNA promoter methylation and reduced expression of PTCH in breast cancer.

Wolf I, Bose S, Desmond JC, Lin BT, Williamson EA, Karlan BY, Koeffler HP.

Breast Cancer Res Treat. 2007 Oct;105(2):139-55. Epub 2007 Feb 13.

PMID:
17295047
37.

Modulation of DNA binding properties of CCAAT/enhancer binding protein epsilon by heterodimer formation and interactions with NFkappaB pathway.

Chumakov AM, Silla A, Williamson EA, Koeffler HP.

Blood. 2007 May 15;109(10):4209-19. Epub 2007 Jan 25.

38.

FOXA1: Growth inhibitor and a favorable prognostic factor in human breast cancer.

Wolf I, Bose S, Williamson EA, Miller CW, Karlan BY, Koeffler HP.

Int J Cancer. 2007 Mar 1;120(5):1013-22.

39.

The SET domain protein Metnase mediates foreign DNA integration and links integration to nonhomologous end-joining repair.

Lee SH, Oshige M, Durant ST, Rasila KK, Williamson EA, Ramsey H, Kwan L, Nickoloff JA, Hromas R.

Proc Natl Acad Sci U S A. 2005 Dec 13;102(50):18075-80. Epub 2005 Dec 6.

40.

BRCA1 and FOXA1 proteins coregulate the expression of the cell cycle-dependent kinase inhibitor p27(Kip1).

Williamson EA, Wolf I, O'Kelly J, Bose S, Tanosaki S, Koeffler HP.

Oncogene. 2006 Mar 2;25(9):1391-9.

PMID:
16331276
41.

Mountain gorilla tug-of-war: silverbacks have limited control over reproduction in multimale groups.

Bradley BJ, Robbins MM, Williamson EA, Steklis HD, Steklis NG, Eckhardt N, Boesch C, Vigilant L.

Proc Natl Acad Sci U S A. 2005 Jun 28;102(26):9418-23. Epub 2005 Jun 17.

42.

CCAAT/enhancer binding protein epsilon: changes in function upon phosphorylation by p38 MAP kinase.

Williamson EA, Williamson IK, Chumakov AM, Friedman AD, Koeffler HP.

Blood. 2005 May 15;105(10):3841-7. Epub 2005 Jan 27.

43.

Characterization of a myeloid tyrosine phosphatase, Lyp, and its role in the Bcr-Abl signal transduction pathway.

Chien W, Tidow N, Williamson EA, Shih LY, Krug U, Kettenbach A, Fermin AC, Roifman CM, Koeffler HP.

J Biol Chem. 2003 Jul 25;278(30):27413-20. Epub 2003 May 21.

44.

Novel therapeutic approach: ligands for PPARgamma and retinoid receptors induce apoptosis in bcl-2-positive human breast cancer cells.

Elstner E, Williamson EA, Zang C, Fritz J, Heber D, Fenner M, Possinger K, Koeffler HP.

Breast Cancer Res Treat. 2002 Jul;74(2):155-65.

PMID:
12186376
45.

BRCA1 transactivates the cyclin-dependent kinase inhibitor p27(Kip1).

Williamson EA, Dadmanesh F, Koeffler HP.

Oncogene. 2002 May 9;21(20):3199-206.

46.

Carriage of infants by a silverback mountain gorilla.

Warren Y, Williamson EA.

Folia Primatol (Basel). 2001 Jul-Aug;72(4):245-7. No abstract available.

PMID:
11713412
47.

Mutational analysis of the peroxisome proliferator-activated receptor gamma gene in human malignancies.

Ikezoe T, Miller CW, Kawano S, Heaney A, Williamson EA, Hisatake J, Green E, Hofmann W, Taguchi H, Koeffler HP.

Cancer Res. 2001 Jul 1;61(13):5307-10.

48.

Holmium: YAG lithotripsy: optimal power settings.

Spore SS, Teichman JM, Corbin NS, Champion PC, Williamson EA, Glickman RD.

J Endourol. 1999 Oct;13(8):559-66.

PMID:
10597125
49.

Regulation of the c-jun gene in p210 BCR-ABL transformed cells corresponds with activity of JNK, the c-jun N-terminal kinase.

Burgess GS, Williamson EA, Cripe LD, Litz-Jackson S, Bhatt JA, Stanley K, Stewart MJ, Kraft AS, Nakshatri H, Boswell HS.

Blood. 1998 Oct 1;92(7):2450-60.

50.

Ligand for peroxisome proliferator-activated receptor gamma (troglitazone) has potent antitumor effect against human prostate cancer both in vitro and in vivo.

Kubota T, Koshizuka K, Williamson EA, Asou H, Said JW, Holden S, Miyoshi I, Koeffler HP.

Cancer Res. 1998 Aug 1;58(15):3344-52.

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