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Items: 1 to 50 of 519

1.

Born to Cry: A Genetic Dissection of Infant Vocalization.

Ashbrook DG, Roy S, Clifford BG, Riede T, Scattoni ML, Heck DH, Lu L, Williams RW.

Front Behav Neurosci. 2018 Oct 29;12:250. doi: 10.3389/fnbeh.2018.00250. eCollection 2018.

2.

Ethanol-Induced Behavioral Sensitization Alters the Synaptic Transcriptome and Exon Utilization in DBA/2J Mice.

O'Brien MA, Weston RM, Sheth NU, Bradley S, Bigbee J, Pandey A, Williams RW, Wolstenholme JT, Miles MF.

Front Genet. 2018 Sep 24;9:402. doi: 10.3389/fgene.2018.00402. eCollection 2018.

3.

Cross-species molecular dissection across alcohol behavioral domains.

Farris SP, Riley BP, Williams RW, Mulligan MK, Miles MF, Lopez MF, Hitzemann R, Iancu OD, Colville A, Walter NAR, Darakjian P, Oberbeck DL, Daunais JB, Zheng CL, Searles RP, McWeeney SK, Grant KA, Mayfield RD.

Alcohol. 2018 Nov;72:19-31. doi: 10.1016/j.alcohol.2017.11.036. Epub 2017 Dec 6. Review.

PMID:
30213503
4.

Potential effect on molecular pathways in different targeted genes in the VEGF family in retina - From the genomic point of view.

Cui J, Liu L, Lu H, Wei D, Jiao Y, Jablonski MM, Williams RW, Gu W, Chen H.

Exp Eye Res. 2018 Nov;176:78-87. doi: 10.1016/j.exer.2018.06.024. Epub 2018 Jun 23.

5.

Reduced oxidative capacity in macrophages results in systemic insulin resistance.

Jung SB, Choi MJ, Ryu D, Yi HS, Lee SE, Chang JY, Chung HK, Kim YK, Kang SG, Lee JH, Kim KS, Kim HJ, Kim CS, Lee CH, Williams RW, Kim H, Lee HK, Auwerx J, Shong M.

Nat Commun. 2018 Apr 19;9(1):1551. doi: 10.1038/s41467-018-03998-z.

6.

A quantitative trait locus on chromosome 1 modulates intermale aggression in mice.

Delprato A, Bonheur B, Algéo MP, Murillo A, Dhawan E, Lu L, Williams RW, Crusio WE.

Genes Brain Behav. 2018 Sep;17(7):e12469. doi: 10.1111/gbb.12469. Epub 2018 Apr 27.

PMID:
29457871
7.

Genetic cartography of longevity in humans and mice: Current landscape and horizons.

Hook M, Roy S, Williams EG, Bou Sleiman M, Mozhui K, Nelson JF, Lu L, Auwerx J, Williams RW.

Biochim Biophys Acta Mol Basis Dis. 2018 Sep;1864(9 Pt A):2718-2732. doi: 10.1016/j.bbadis.2018.01.026. Epub 2018 Feb 2. Review.

PMID:
29410319
8.

A Spontaneous Mutation in Taar1 Impacts Methamphetamine-Related Traits Exclusively in DBA/2 Mice from a Single Vendor.

Reed C, Baba H, Zhu Z, Erk J, Mootz JR, Varra NM, Williams RW, Phillips TJ.

Front Pharmacol. 2018 Jan 22;8:993. doi: 10.3389/fphar.2017.00993. eCollection 2017.

9.

Teaching with Big Data: Report from the 2016 Society for Neuroscience Teaching Workshop.

Grisham W, Brumberg JC, Gilbert T, Lanyon L, Williams RW, Olivo R.

J Undergrad Neurosci Educ. 2017 Nov 15;16(1):A68-A76. eCollection 2017 Fall.

10.

Reproducibility and replicability of rodent phenotyping in preclinical studies.

Kafkafi N, Agassi J, Chesler EJ, Crabbe JC, Crusio WE, Eilam D, Gerlai R, Golani I, Gomez-Marin A, Heller R, Iraqi F, Jaljuli I, Karp NA, Morgan H, Nicholson G, Pfaff DW, Richter SH, Stark PB, Stiedl O, Stodden V, Tarantino LM, Tucci V, Valdar W, Williams RW, Würbel H, Benjamini Y.

Neurosci Biobehav Rev. 2018 Apr;87:218-232. doi: 10.1016/j.neubiorev.2018.01.003. Epub 2018 Jan 31. Review.

11.

An Integrated Systems Genetics and Omics Toolkit to Probe Gene Function.

Li H, Wang X, Rukina D, Huang Q, Lin T, Sorrentino V, Zhang H, Bou Sleiman M, Arends D, McDaid A, Luan P, Ziari N, Velázquez-Villegas LA, Gariani K, Kutalik Z, Schoonjans K, Radcliffe RA, Prins P, Morgenthaler S, Williams RW, Auwerx J.

Cell Syst. 2018 Jan 24;6(1):90-102.e4. doi: 10.1016/j.cels.2017.10.016. Epub 2017 Nov 30.

12.

Post-genomic behavioral genetics: From revolution to routine.

Ashbrook DG, Mulligan MK, Williams RW.

Genes Brain Behav. 2018 Mar;17(3):e12441. doi: 10.1111/gbb.12441. Epub 2017 Dec 21. Review.

PMID:
29193773
13.

Systems genetics identifies a role for Cacna2d1 regulation in elevated intraocular pressure and glaucoma susceptibility.

Chintalapudi SR, Maria D, Di Wang X, Bailey JNC; NEIGHBORHOOD consortium; International Glaucoma Genetics consortium, Hysi PG, Wiggs JL, Williams RW, Jablonski MM.

Nat Commun. 2017 Nov 24;8(1):1755. doi: 10.1038/s41467-017-00837-5.

14.

Genetic Analysis of Mitochondrial Ribosomal Proteins and Cognitive Aging in Postmenopausal Women.

Mozhui K, Snively BM, Rapp SR, Wallace RB, Williams RW, Johnson KC.

Front Genet. 2017 Sep 21;8:127. doi: 10.3389/fgene.2017.00127. eCollection 2017.

15.

Overexpression of RING Domain E3 Ligase ZmXerico1 Confers Drought Tolerance through Regulation of ABA Homeostasis.

Brugière N, Zhang W, Xu Q, Scolaro EJ, Lu C, Kahsay RY, Kise R, Trecker L, Williams RW, Hakimi S, Niu X, Lafitte R, Habben JE.

Plant Physiol. 2017 Nov;175(3):1350-1369. doi: 10.1104/pp.17.01072. Epub 2017 Sep 12.

16.

Success rates and complications of autologous onlay bone grafts and sinus lifts in patients with congenital hypodontia and after trauma.

Breeze J, Patel J, Dover MS, Williams RW.

Br J Oral Maxillofac Surg. 2017 Oct;55(8):830-833. doi: 10.1016/j.bjoms.2017.08.001. Epub 2017 Aug 30.

PMID:
28869085
17.

High-Resolution Maps of Mouse Reference Populations.

Simecek P, Forejt J, Williams RW, Shiroishi T, Takada T, Lu L, Johnson TE, Bennett B, Deschepper CF, Scott-Boyer MP, Pardo-Manuel de Villena F, Churchill GA.

G3 (Bethesda). 2017 Oct 5;7(10):3427-3434. doi: 10.1534/g3.117.300188.

18.

A new thorium-229 reference material.

Essex RM, Mann JL, Williams RW, Kinman WS, Hubert A, Bennett ME, Gourgiotis A.

Appl Radiat Isot. 2018 Apr;134:23-31. doi: 10.1016/j.apradiso.2017.07.050. Epub 2017 Jul 27.

PMID:
28784354
19.

Patients experiencing statin-induced myalgia exhibit a unique program of skeletal muscle gene expression following statin re-challenge.

Elam MB, Majumdar G, Mozhui K, Gerling IC, Vera SR, Fish-Trotter H, Williams RW, Childress RD, Raghow R.

PLoS One. 2017 Aug 3;12(8):e0181308. doi: 10.1371/journal.pone.0181308. eCollection 2017.

20.

Bayesian association scan reveals loci associated with human lifespan and linked biomarkers.

McDaid AF, Joshi PK, Porcu E, Komljenovic A, Li H, Sorrentino V, Litovchenko M, Bevers RPJ, Rüeger S, Reymond A, Bochud M, Deplancke B, Williams RW, Robinson-Rechavi M, Paccaud F, Rousson V, Auwerx J, Wilson JF, Kutalik Z.

Nat Commun. 2017 Jul 27;8:15842. doi: 10.1038/ncomms15842.

21.

Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals.

Quirós PM, Prado MA, Zamboni N, D'Amico D, Williams RW, Finley D, Gygi SP, Auwerx J.

J Cell Biol. 2017 Jul 3;216(7):2027-2045. doi: 10.1083/jcb.201702058. Epub 2017 May 31.

22.

QTL and systems genetics analysis of mouse grooming and behavioral responses to novelty in an open field.

Delprato A, Algéo MP, Bonheur B, Bubier JA, Lu L, Williams RW, Chesler EJ, Crusio WE.

Genes Brain Behav. 2017 Nov;16(8):790-799. doi: 10.1111/gbb.12392. Epub 2017 Jun 22.

23.

Genetic control of oromotor phenotypes: A survey of licking and ingestive behaviors in highly diverse strains of mice.

St John SJ, Lu L, Williams RW, Saputra J, Boughter JD Jr.

Physiol Behav. 2017 Aug 1;177:34-43. doi: 10.1016/j.physbeh.2017.04.007. Epub 2017 Apr 12.

24.

Contemporary surgical management of hypodontia.

Breeze J, Dover MS, Williams RW.

Br J Oral Maxillofac Surg. 2017 Jun;55(5):454-460. doi: 10.1016/j.bjoms.2017.03.013. Epub 2017 Apr 12. Review.

PMID:
28410841
25.

Orbitofrontal Neuroadaptations and Cross-Species Synaptic Biomarkers in Heavy-Drinking Macaques.

Nimitvilai S, Uys JD, Woodward JJ, Randall PK, Ball LE, Williams RW, Jones BC, Lu L, Grant KA, Mulholland PJ.

J Neurosci. 2017 Mar 29;37(13):3646-3660. doi: 10.1523/JNEUROSCI.0133-17.2017. Epub 2017 Mar 7.

26.

Genetic Variation in the Social Environment Contributes to Health and Disease.

Baud A, Mulligan MK, Casale FP, Ingels JF, Bohl CJ, Callebert J, Launay JM, Krohn J, Legarra A, Williams RW, Stegle O.

PLoS Genet. 2017 Jan 25;13(1):e1006498. doi: 10.1371/journal.pgen.1006498. eCollection 2017 Jan.

27.

GeneNetwork: A Toolbox for Systems Genetics.

Mulligan MK, Mozhui K, Prins P, Williams RW.

Methods Mol Biol. 2017;1488:75-120.

PMID:
27933521
28.

Resources for Systems Genetics.

Williams RW, Williams EG.

Methods Mol Biol. 2017;1488:3-29.

PMID:
27933518
29.

Preface to a special issue on genetic models of alcoholism and alcohol-stress interactions.

Williams RW, Holmes A.

Alcohol. 2017 Feb;58:23-24. doi: 10.1016/j.alcohol.2016.11.010. Epub 2016 Nov 23. No abstract available.

PMID:
27912921
30.

Genetic divergence in the transcriptional engram of chronic alcohol abuse: A laser-capture RNA-seq study of the mouse mesocorticolimbic system.

Mulligan MK, Mozhui K, Pandey AK, Smith ML, Gong S, Ingels J, Miles MF, Lopez MF, Lu L, Williams RW.

Alcohol. 2017 Feb;58:61-72. doi: 10.1016/j.alcohol.2016.09.001. Epub 2016 Oct 15.

31.

Initial genetic dissection of serum neuroactive steroids following chronic intermittent ethanol across BXD mouse strains.

Porcu P, O'Buckley TK, Lopez MF, Becker HC, Miles MF, Williams RW, Morrow AL.

Alcohol. 2017 Feb;58:107-125. doi: 10.1016/j.alcohol.2016.07.011. Epub 2016 Nov 10.

32.

Genetic and immunohistochemical analysis of HSPA5 in mouse and human retinas.

Chintalapudi SR, Wang X, Li H, Lau YH, Williams RW, Jablonski MM.

Mol Vis. 2016 Nov 10;22:1318-1331. eCollection 2016.

33.

A Retrospective Look at North Carolina's Efforts to Reduce Infant Mortality.

Prestia BM, Rhodes J, Williams RW.

N C Med J. 2016 Nov-Dec;77(6):411-412. No abstract available.

34.

The allostatic impact of chronic ethanol on gene expression: A genetic analysis of chronic intermittent ethanol treatment in the BXD cohort.

van der Vaart AD, Wolstenholme JT, Smith ML, Harris GM, Lopez MF, Wolen AR, Becker HC, Williams RW, Miles MF.

Alcohol. 2017 Feb;58:93-106. doi: 10.1016/j.alcohol.2016.07.010. Epub 2016 Nov 1.

35.

Variable effects of chronic intermittent ethanol exposure on ethanol drinking in a genetically diverse mouse cohort.

Lopez MF, Miles MF, Williams RW, Becker HC.

Alcohol. 2017 Feb;58:73-82. doi: 10.1016/j.alcohol.2016.09.003. Epub 2016 Oct 13.

36.

Genetic Networks in Mouse Retinal Ganglion Cells.

Struebing FL, Lee RK, Williams RW, Geisert EE.

Front Genet. 2016 Sep 28;7:169. eCollection 2016.

37.

Systems genetics identifies Hp1bp3 as a novel modulator of cognitive aging.

Neuner SM, Garfinkel BP, Wilmott LA, Ignatowska-Jankowska BM, Citri A, Orly J, Lu L, Overall RW, Mulligan MK, Kempermann G, Williams RW, O'Connell KM, Kaczorowski CC.

Neurobiol Aging. 2016 Oct;46:58-67. doi: 10.1016/j.neurobiolaging.2016.06.008. Epub 2016 Jun 17.

38.

Differential potassium channel gene regulation in BXD mice reveals novel targets for pharmacogenetic therapies to reduce heavy alcohol drinking.

Rinker JA, Fulmer DB, Trantham-Davidson H, Smith ML, Williams RW, Lopez MF, Randall PK, Chandler LJ, Miles MF, Becker HC, Mulholland PJ.

Alcohol. 2017 Feb;58:33-45. doi: 10.1016/j.alcohol.2016.05.007. Epub 2016 Jun 27.

39.

MPTP neurotoxicity is highly concordant between the sexes among BXD recombinant inbred mouse strains.

Alam G, Miller DB, O'Callaghan JP, Lu L, Williams RW, Jones BC.

Neurotoxicology. 2016 Jul;55:40-47. doi: 10.1016/j.neuro.2016.04.008. Epub 2016 May 12.

40.

Genetic Polymorphisms Affect Mouse and Human Trace Amine-Associated Receptor 1 Function.

Shi X, Walter NA, Harkness JH, Neve KA, Williams RW, Lu L, Belknap JK, Eshleman AJ, Phillips TJ, Janowsky A.

PLoS One. 2016 Mar 31;11(3):e0152581. doi: 10.1371/journal.pone.0152581. eCollection 2016.

41.
42.

The Genetic Basis of Baculum Size and Shape Variation in Mice.

Schultz NG, Ingels J, Hillhouse A, Wardwell K, Chang PL, Cheverud JM, Lutz C, Lu L, Williams RW, Dean MD.

G3 (Bethesda). 2016 May 3;6(5):1141-51. doi: 10.1534/g3.116.027888.

43.

Joint mouse-human phenome-wide association to test gene function and disease risk.

Wang X, Pandey AK, Mulligan MK, Williams EG, Mozhui K, Li Z, Jovaisaite V, Quarles LD, Xiao Z, Huang J, Capra JA, Chen Z, Taylor WL, Bastarache L, Niu X, Pollard KS, Ciobanu DC, Reznik AO, Tishkov AV, Zhulin IB, Peng J, Nelson SF, Denny JC, Auwerx J, Lu L, Williams RW.

Nat Commun. 2016 Feb 2;7:10464. doi: 10.1038/ncomms10464.

44.

Impact of genetic variation on synaptic protein levels in genetically diverse mice.

Loos M, Li KW, van der Schors R, Gouwenberg Y, van der Loo R, Williams RW, Smit AB, Spijker S.

Proteomics. 2016 Apr;16(7):1123-30. doi: 10.1002/pmic.201500154. Epub 2016 Mar 10.

PMID:
26786964
45.

Multipronged approach to identify and validate a novel upstream regulator of Sncg in mouse retinal ganglion cells.

Chintalapudi SR, Morales-Tirado VM, Williams RW, Jablonski MM.

FEBS J. 2016 Feb;283(4):678-93. doi: 10.1111/febs.13620. Epub 2016 Jan 18.

46.

Transcriptome networks in the mouse retina: An exon level BXD RI database.

King R, Lu L, Williams RW, Geisert EE.

Mol Vis. 2015 Oct 26;21:1235-51. eCollection 2015.

47.

Air Pollution Exposure Model for Individuals (EMI) in Health Studies: Evaluation for Ambient PM2.5 in Central North Carolina.

Breen MS, Long TC, Schultz BD, Williams RW, Richmond-Bryant J, Breen M, Langstaff JE, Devlin RB, Schneider A, Burke JM, Batterman SA, Meng QY.

Environ Sci Technol. 2015 Dec 15;49(24):14184-94. doi: 10.1021/acs.est.5b02765. Epub 2015 Nov 12.

PMID:
26561729
48.

Systems genetic analysis of hippocampal neuroanatomy and spatial learning in mice.

Delprato A, Bonheur B, Algéo MP, Rosay P, Lu L, Williams RW, Crusio WE.

Genes Brain Behav. 2015 Nov;14(8):591-606. doi: 10.1111/gbb.12259. Epub 2015 Nov 8.

49.

A Murine Hypertrophic Cardiomyopathy Model: The DBA/2J Strain.

Zhao W, Zhao T, Chen Y, Zhao F, Gu Q, Williams RW, Bhattacharya SK, Lu L, Sun Y.

PLoS One. 2015 Aug 4;10(8):e0133132. doi: 10.1371/journal.pone.0133132. eCollection 2015.

50.

Overexpression of ARGOS Genes Modifies Plant Sensitivity to Ethylene, Leading to Improved Drought Tolerance in Both Arabidopsis and Maize.

Shi J, Habben JE, Archibald RL, Drummond BJ, Chamberlin MA, Williams RW, Lafitte HR, Weers BP.

Plant Physiol. 2015 Sep;169(1):266-82. doi: 10.1104/pp.15.00780. Epub 2015 Jul 28.

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