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Items: 1 to 50 of 272

1.

A New Animal Model of Insulin-Glucose Dynamics in the Intraperitoneal Space Enhances Closed-Loop Control Performance.

Chakrabarty A, Gregory JM, Moore LM, Williams PE, Farmer B, Cherrington AD, Lord P, Shelton B, Cohen D, Zisser HC, Doyle FJ 3rd, Dassau E.

J Process Control. 2019 Apr;76:62-73. doi: 10.1016/j.jprocont.2019.01.002. Epub 2019 Feb 23.

PMID:
31178632
2.

Sympathetic Denervation of the Common Hepatic Artery Lessens Glucose Intolerance in the Fat- and Fructose-Fed Dog.

Kraft G, Vrba A, Scott M, Allen E, Edgerton DS, Williams PE, Vafai SB, Azamian BR, Cherrington AD.

Diabetes. 2019 Jun;68(6):1143-1155. doi: 10.2337/db18-1209. Epub 2019 Apr 1.

PMID:
30936143
3.

Characterization of Antigenic Oligosaccharides from Gram-Negative Bacteria via Activated Electron Photodetachment Mass Spectrometry.

Crittenden CM, Escobar EE, Williams PE, Sanders JD, Brodbelt JS.

Anal Chem. 2019 Apr 2;91(7):4672-4679. doi: 10.1021/acs.analchem.9b00048. Epub 2019 Mar 15.

PMID:
30844257
4.

Targeting insulin to the liver corrects defects in glucose metabolism caused by peripheral insulin delivery.

Edgerton DS, Scott M, Farmer B, Williams PE, Madsen P, Kjeldsen T, Brand CL, Fledelius C, Nishimura E, Cherrington AD.

JCI Insight. 2019 Feb 26;5. pii: 126974. doi: 10.1172/jci.insight.126974.

5.

Enterically delivered insulin tregopil exhibits rapid absorption characteristics and a pharmacodynamic effect similar to human insulin in conscious dogs.

Gregory JM, Lautz M, Moore LM, Williams PE, Reddy P, Cherrington AD.

Diabetes Obes Metab. 2019 Jan;21(1):160-169. doi: 10.1111/dom.13498. Epub 2018 Sep 16.

PMID:
30095210
6.

Stress Dissipation in Cucurbit[8]uril Ternary Complex Small Molecule Adhesives.

Williams PE, Walsh-Korb Z, Jones ST, Lan Y, Scherman OA.

Langmuir. 2018 Nov 6;34(44):13104-13109. doi: 10.1021/acs.langmuir.8b00894. Epub 2018 Oct 22.

PMID:
29965772
7.

Mapping phosphate modifications of substituted lipid A via a targeted MS3 CID/UVPD strategy.

Crittenden CM, Herrera CM, Williams PE, Ricci DP, Swem LR, Trent MS, Brodbelt JS.

Analyst. 2018 Jun 25;143(13):3091-3099. doi: 10.1039/c8an00561c.

8.

Comparing Positively and Negatively Charged Distonic Radical Ions in Phenylperoxyl Forming Reactions.

Williams PE, Marshall DL, Poad BLJ, Narreddula VR, Kirk BB, Trevitt AJ, Blanksby SJ.

J Am Soc Mass Spectrom. 2018 Sep;29(9):1848-1860. doi: 10.1007/s13361-018-1988-9. Epub 2018 Jun 4.

PMID:
29869328
9.

Morning Hyperinsulinemia Primes the Liver for Glucose Uptake and Glycogen Storage Later in the Day.

Moore MC, Smith MS, Farmer B, Coate KC, Kraft G, Shiota M, Williams PE, Cherrington AD.

Diabetes. 2018 Jul;67(7):1237-1245. doi: 10.2337/db17-0979. Epub 2018 Apr 17.

10.

Pharmacokinetics, Tissue Localization, Toxicity, and Treatment Efficacy in the First Small Animal (Rabbit) Model of Intra-Arterial Chemotherapy for Retinoblastoma.

Daniels AB, Froehler MT, Pierce JM, Nunnally AH, Calcutt MW, Bridges TM, LaNeve DC, Williams PE, Boyd KL, Reyzer ML, Lindsley CW, Friedman DL, Richmond A.

Invest Ophthalmol Vis Sci. 2018 Jan 1;59(1):446-454. doi: 10.1167/iovs.17-22302.

11.

Pinpointing Double Bond and sn-Positions in Glycerophospholipids via Hybrid 193 nm Ultraviolet Photodissociation (UVPD) Mass Spectrometry.

Williams PE, Klein DR, Greer SM, Brodbelt JS.

J Am Chem Soc. 2017 Nov 8;139(44):15681-15690. doi: 10.1021/jacs.7b06416. Epub 2017 Oct 25.

12.

Long-acting intramuscular cabotegravir and rilpivirine in adults with HIV-1 infection (LATTE-2): 96-week results of a randomised, open-label, phase 2b, non-inferiority trial.

Margolis DA, Gonzalez-Garcia J, Stellbrink HJ, Eron JJ, Yazdanpanah Y, Podzamczer D, Lutz T, Angel JB, Richmond GJ, Clotet B, Gutierrez F, Sloan L, Clair MS, Murray M, Ford SL, Mrus J, Patel P, Crauwels H, Griffith SK, Sutton KC, Dorey D, Smith KY, Williams PE, Spreen WR.

Lancet. 2017 Sep 23;390(10101):1499-1510. doi: 10.1016/S0140-6736(17)31917-7. Epub 2017 Jul 24.

PMID:
28750935
13.

Glucagon's effect on liver protein metabolism in vivo.

Kraft G, Coate KC, Winnick JJ, Dardevet D, Donahue EP, Cherrington AD, Williams PE, Moore MC.

Am J Physiol Endocrinol Metab. 2017 Sep 1;313(3):E263-E272. doi: 10.1152/ajpendo.00045.2017. Epub 2017 May 23.

14.

Glucose autoregulation is the dominant component of the hormone-independent counterregulatory response to hypoglycemia in the conscious dog.

Gregory JM, Rivera N, Kraft G, Winnick JJ, Farmer B, Allen EJ, Donahue EP, Smith MS, Edgerton DS, Williams PE, Cherrington AD.

Am J Physiol Endocrinol Metab. 2017 Sep 1;313(3):E273-E283. doi: 10.1152/ajpendo.00099.2017. Epub 2017 May 16.

15.

Comparison of the Performance of Skin Prick, ImmunoCAP, and ISAC Tests in the Diagnosis of Patients with Allergy.

Griffiths RLM, El-Shanawany T, Jolles SRA, Selwood C, Heaps AG, Carne EM, Williams PE.

Int Arch Allergy Immunol. 2017;172(4):215-223. doi: 10.1159/000464326. Epub 2017 Apr 29.

16.

Insulin's direct hepatic effect explains the inhibition of glucose production caused by insulin secretion.

Edgerton DS, Kraft G, Smith M, Farmer B, Williams PE, Coate KC, Printz RL, O'Brien RM, Cherrington AD.

JCI Insight. 2017 Mar 23;2(6):e91863. doi: 10.1172/jci.insight.91863.

17.

Priming Effect of a Morning Meal on Hepatic Glucose Disposition Later in the Day.

Moore MC, Smith MS, Farmer B, Kraft G, Shiota M, Williams PE, Cherrington AD.

Diabetes. 2017 May;66(5):1136-1145. doi: 10.2337/db16-1308. Epub 2017 Feb 7.

18.

Single-Molecule Force Spectroscopy Quantification of Adhesive Forces in Cucurbit[8]Uril Host-Guest Ternary Complexes.

Walsh-Korb Z, Yu Y, Janeček ER, Lan Y, Del Barrio J, Williams PE, Zhang X, Scherman OA.

Langmuir. 2017 Feb 14;33(6):1343-1350. doi: 10.1021/acs.langmuir.6b03457. Epub 2017 Feb 3.

PMID:
28055217
19.

Long-acting rilpivirine as potential pre-exposure prophylaxis for HIV-1 prevention (the MWRI-01 study): an open-label, phase 1, compartmental, pharmacokinetic and pharmacodynamic assessment.

McGowan I, Dezzutti CS, Siegel A, Engstrom J, Nikiforov A, Duffill K, Shetler C, Richardson-Harman N, Abebe K, Back D, Else L, Egan D, Khoo S, Egan JE, Stall R, Williams PE, Rehman KK, Adler A, Brand RM, Chen B, Achilles S, Cranston RD.

Lancet HIV. 2016 Dec;3(12):e569-e578. doi: 10.1016/S2352-3018(16)30113-8. Epub 2016 Sep 16.

PMID:
27658864
20.

Hepatic and Whole-Body Insulin Metabolism during Proestrus and Estrus in Mongrel Dogs.

Yu EN, Winnick JJ, Edgerton DS, Scott MF, Smith MS, Farmer B, Williams PE, Cherrington AD, Moore MC.

Comp Med. 2016;66(3):235-40.

21.

The bio refinery; producing feed and fuel from grain.

Scholey DV, Burton EJ, Williams PE.

Food Chem. 2016 Apr 15;197(Pt A):937-42. doi: 10.1016/j.foodchem.2015.11.063. Epub 2015 Nov 14. Review.

PMID:
26617037
22.

Quantitative Imaging Assessment of an Alternative Approach to Surgical Mitral Valve Leaflet Resection: An Acute Porcine Study.

Boronyak SM, Fredi JL, Young MN, Dumont DM, Williams PE, Byram BC, Merryman WD.

Ann Biomed Eng. 2016 Jul;44(7):2240-50. doi: 10.1007/s10439-015-1494-1. Epub 2015 Oct 27.

23.

Protocol for investigation of possible soya allergy in patients being considered for treatment with isotretinoin or alitretinoin.

Alden K, Chowdhury MM, Williams PE, Kalavala M.

Clin Exp Dermatol. 2016 Apr;41(3):326-7. doi: 10.1111/ced.12762. Epub 2015 Oct 9. No abstract available.

PMID:
26452340
24.

Mass spectrometric identification of the N-monosubstituted N-hydroxylamino functionality in protonated analytes via ion/molecule reactions in tandem mass spectrometry.

Sheng H, Tang W, Yerabolu R, Kong JY, Williams PE, Zhang M, Kenttämaa HI.

Rapid Commun Mass Spectrom. 2015 Apr 30;29(8):730-4. doi: 10.1002/rcm.7154.

PMID:
26406487
25.

Cabotegravir plus rilpivirine, once a day, after induction with cabotegravir plus nucleoside reverse transcriptase inhibitors in antiretroviral-naive adults with HIV-1 infection (LATTE): a randomised, phase 2b, dose-ranging trial.

Margolis DA, Brinson CC, Smith GHR, de Vente J, Hagins DP, Eron JJ, Griffith SK, Clair MHS, Stevens MC, Williams PE, Ford SL, Stancil BS, Bomar MM, Hudson KJ, Smith KY, Spreen WR; LAI116482 Study Team.

Lancet Infect Dis. 2015 Oct;15(10):1145-1155. doi: 10.1016/S1473-3099(15)00152-8. Epub 2015 Jul 19.

PMID:
26201299
26.

Bile diversion to the distal small intestine has comparable metabolic benefits to bariatric surgery.

Flynn CR, Albaugh VL, Cai S, Cheung-Flynn J, Williams PE, Brucker RM, Bordenstein SR, Guo Y, Wasserman DH, Abumrad NN.

Nat Commun. 2015 Jul 21;6:7715. doi: 10.1038/ncomms8715.

27.

Formulation and pharmacology of long-acting rilpivirine.

Williams PE, Crauwels HM, Basstanie ED.

Curr Opin HIV AIDS. 2015 Jul;10(4):233-8. doi: 10.1097/COH.0000000000000164. Review.

PMID:
26049947
28.

Identification of the sulfoxide functionality in protonated analytes via ion/molecule reactions in linear quadrupole ion trap mass spectrometry.

Sheng H, Williams PE, Tang W, Zhang M, Kenttämaa HI.

Analyst. 2014 Sep 7;139(17):4296-302. doi: 10.1039/c4an00677a.

PMID:
24968187
29.

Identification of the sulfone functionality in protonated analytes via ion/molecule reactions in a linear quadrupole ion trap mass spectrometer.

Sheng H, Williams PE, Tang W, Riedeman JS, Zhang M, Kenttämaa HI.

J Org Chem. 2014 Apr 4;79(7):2883-9. doi: 10.1021/jo402645a. Epub 2014 Mar 17.

PMID:
24571420
30.

Liver, but not muscle, has an entrainable metabolic memory.

Chen SS, Otero YF, Mulligan KX, Lundblad TM, Williams PE, McGuinness OP.

PLoS One. 2014 Jan 23;9(1):e86164. doi: 10.1371/journal.pone.0086164. eCollection 2014.

31.

Properties and reactivity of gaseous distonic radical ions with aryl radical sites.

Williams PE, Jankiewicz BJ, Yang L, Kenttämaa HI.

Chem Rev. 2013 Sep 11;113(9):6949-85. doi: 10.1021/cr400121w. Epub 2013 Aug 29. Review. No abstract available.

32.

UV-induced effects on chlorination of creatinine.

Weng SC, Li J, Wood KV, Kenttämaa HI, Williams PE, Amundson LM, Blatchley ER 3rd.

Water Res. 2013 Sep 15;47(14):4948-56. doi: 10.1016/j.watres.2013.05.034. Epub 2013 May 31.

PMID:
23863372
33.

B cells assist allograft rejection in the deficiency of protein kinase c-theta.

Yan W, Xu R, Ma LL, Han W, Geevarghese SK, Williams PE, Sciammas R, Chong AS, Yin DP.

Transpl Int. 2013 Sep;26(9):919-27. doi: 10.1111/tri.12143. Epub 2013 Jul 11.

34.

Canine body composition quantification using 3 tesla fat-water MRI.

Gifford A, Kullberg J, Berglund J, Malmberg F, Coate KC, Williams PE, Cherrington AD, Avison MJ, Welch EB.

J Magn Reson Imaging. 2014 Feb;39(2):485-91. doi: 10.1002/jmri.24156. Epub 2013 Apr 17.

35.

Hepatic glucose metabolism in late pregnancy: normal versus high-fat and -fructose diet.

Coate KC, Smith MS, Shiota M, Irimia JM, Roach PJ, Farmer B, Williams PE, Moore MC.

Diabetes. 2013 Mar;62(3):753-61. doi: 10.2337/db12-0875. Epub 2012 Dec 6.

36.

Mouse Models of Bariatric Surgery.

Yin DP, Boyd KL, Williams PE, Abumrad NN, Wasserman DH.

Curr Protoc Mouse Biol. 2012 Dec 1;2012. pii: mo120087.

37.

Interaction between the central and peripheral effects of insulin in controlling hepatic glucose metabolism in the conscious dog.

Ramnanan CJ, Kraft G, Smith MS, Farmer B, Neal D, Williams PE, Lautz M, Farmer T, Donahue EP, Cherrington AD, Edgerton DS.

Diabetes. 2013 Jan;62(1):74-84. doi: 10.2337/db12-0148. Epub 2012 Sep 25.

38.

Portal glucose delivery stimulates muscle but not liver protein metabolism.

Kraft G, Coate KC, Dardevet D, Farmer B, Donahue EP, Williams PE, Cherrington AD, Moore MC.

Am J Physiol Endocrinol Metab. 2012 Nov 15;303(10):E1202-11. doi: 10.1152/ajpendo.00140.2012. Epub 2012 Sep 25.

39.

Mouse Models of Bariatric Surgery.

Yin DP, Boyd KL, Williams PE, Abumrad NN, Wasserman DH.

Curr Protoc Mouse Biol. 2012 Dec 1;2(4):295-306. doi: 10.1002/9780470942390.mo120087.

PMID:
26069016
40.

Brain insulin action augments hepatic glycogen synthesis without suppressing glucose production or gluconeogenesis in dogs.

Ramnanan CJ, Saraswathi V, Smith MS, Donahue EP, Farmer B, Farmer TD, Neal D, Williams PE, Lautz M, Mari A, Cherrington AD, Edgerton DS.

J Clin Invest. 2011 Sep;121(9):3713-23. doi: 10.1172/JCI45472. Epub 2011 Aug 25.

41.

Comparison of insulins detemir and glargine: effects on glucose disposal, hepatic glucose release and the central nervous system.

Moore MC, Smith MS, Turney MK, Boysen S, Williams PE.

Diabetes Obes Metab. 2011 Sep;13(9):832-40. doi: 10.1111/j.1463-1326.2011.01418.x.

42.

Assessment of different bariatric surgeries in the treatment of obesity and insulin resistance in mice.

Yin DP, Gao Q, Ma LL, Yan W, Williams PE, McGuinness OP, Wasserman DH, Abumrad NN.

Ann Surg. 2011 Jul;254(1):73-82. doi: 10.1097/SLA.0b013e3182197035.

43.

Diet-induced impaired glucose tolerance and gestational diabetes in the dog.

Moore MC, Menon R, Coate KC, Gannon M, Smith MS, Farmer B, Williams PE.

J Appl Physiol (1985). 2011 Feb;110(2):458-67. doi: 10.1152/japplphysiol.00768.2010. Epub 2010 Nov 18.

44.

Continuous low-dose fructose infusion does not reverse glucagon-mediated decrease in hepatic glucose utilization.

Johnson PM, Chen SS, Santomango TS, Williams PE, Lacy DB, McGuinness OP.

Metabolism. 2011 Jun;60(6):867-73. doi: 10.1016/j.metabol.2010.08.006. Epub 2010 Oct 12.

45.

Effects of insulin on the metabolic control of hepatic gluconeogenesis in vivo.

Edgerton DS, Ramnanan CJ, Grueter CA, Johnson KM, Lautz M, Neal DW, Williams PE, Cherrington AD.

Diabetes. 2009 Dec;58(12):2766-75. doi: 10.2337/db09-0328. Epub 2009 Sep 15.

46.

Stimulus ensemble and cortical layer determine V1 spatial receptive fields.

Yeh CI, Xing D, Williams PE, Shapley RM.

Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14652-7. doi: 10.1073/pnas.0907406106. Epub 2009 Aug 17. Erratum in: Proc Natl Acad Sci U S A. 2009 Sep 29;106(39):16890.

47.

Glucagon-mediated impairments in hepatic and peripheral tissue nutrient disposal are not aggravated by increased lipid availability.

Chen SS, Santomango TS, Williams PE, Lacy DB, McGuinness OP.

Am J Physiol Endocrinol Metab. 2009 May;296(5):E1172-8. doi: 10.1152/ajpendo.90821.2008. Epub 2009 Feb 10.

48.

Clinical immunology review series: an approach to the patient with anaphylaxis.

El-Shanawany T, Williams PE, Jolles S.

Clin Exp Immunol. 2008 Jul;153(1):1-9. doi: 10.1111/j.1365-2249.2008.03694.x. Review.

49.

Hepatic portal venous delivery of a nitric oxide synthase inhibitor enhances net hepatic glucose uptake.

Moore MC, Dicostanzo CA, Smith MS, Farmer B, Rodewald TD, Neal DW, Williams PE, Cherrington AD.

Am J Physiol Endocrinol Metab. 2008 Apr;294(4):E768-77. doi: 10.1152/ajpendo.00184.2007. Epub 2008 Jan 22.

50.

A dynamic nonlinearity and spatial phase specificity in macaque V1 neurons.

Williams PE, Shapley RM.

J Neurosci. 2007 May 23;27(21):5706-18.

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