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Items: 1 to 50 of 469

1.

A Strategy for Probing the Evolution of Crystallization Processes by Low-Temperature Solid-State NMR and Dynamic Nuclear Polarization.

Vioglio PC, Thureau P, Juramy M, Ziarelli F, Viel S, Williams PA, Hughes CE, Harris KDM, Mollica G.

J Phys Chem Lett. 2019 Mar 18:1505-1510. doi: 10.1021/acs.jpclett.9b00306. [Epub ahead of print]

PMID:
30882228
2.

Correction: Cryo-EM in drug discovery.

Ceska T, Chung CW, Cooke R, Phillips C, Williams PA.

Biochem Soc Trans. 2019 Feb 28;47(1):487. doi: 10.1042/BST-2018-0267C_COR. No abstract available.

PMID:
30819927
3.

Monogenic causes of chronic kidney disease in adults.

Connaughton DM, Kennedy C, Shril S, Mann N, Murray SL, Williams PA, Conlon E, Nakayama M, van der Ven AT, Ityel H, Kause F, Kolvenbach CM, Dai R, Vivante A, Braun DA, Schneider R, Kitzler TM, Moloney B, Moran CP, Smyth JS, Kennedy A, Benson K, Stapleton C, Denton M, Magee C, O'Seaghdha CM, Plant WD, Griffin MD, Awan A, Sweeney C, Mane SM, Lifton RP, Griffin B, Leavey S, Casserly L, de Freitas DG, Holian J, Dorman A, Doyle B, Lavin PJ, Little MA, Conlon PJ, Hildebrandt F.

Kidney Int. 2019 Feb 12. pii: S0085-2538(18)30839-1. doi: 10.1016/j.kint.2018.10.031. [Epub ahead of print]

PMID:
30773290
4.

Inhibition of monocyte-like cell extravasation protects from neurodegeneration in DBA/2J glaucoma.

Williams PA, Braine CE, Kizhatil K, Foxworth NE, Tolman NG, Harder JM, Scott RA, Sousa GL, Panitch A, Howell GR, John SWM.

Mol Neurodegener. 2019 Jan 22;14(1):6. doi: 10.1186/s13024-018-0303-3.

5.

Cryo-EM in drug discovery.

Ceska T, Chung CW, Cooke R, Phillips C, Williams PA.

Biochem Soc Trans. 2019 Feb 28;47(1):281-293. doi: 10.1042/BST20180267. Epub 2019 Jan 15. Review. Erratum in: Biochem Soc Trans. 2019 Feb 28;47(1):487.

PMID:
30647139
6.

Improving Digital Hospital Transformation: Development of an Outcomes-Based Infrastructure Maturity Assessment Framework.

Williams PA, Lovelock B, Cabarrus T, Harvey M.

JMIR Med Inform. 2019 Jan 11;7(1):e12465. doi: 10.2196/12465.

7.

Synthesis, characterization, theoretical studies and biological (antioxidant, anticancer, toxicity and neuroprotective) determinations of a copper(II) complex with 5-hydroxytryptophan.

Martínez Medina JJ, Naso LG, Pérez AL, Rizzi A, Okulik NB, Valcarcel M, Salado C, Ferrer EG, Williams PAM.

Biomed Pharmacother. 2019 Mar;111:414-426. doi: 10.1016/j.biopha.2018.12.098. Epub 2018 Dec 27.

8.

RNA regulons are essential in intestinal homeostasis.

Parham LR, Williams PA, Chatterji P, Whelan KA, Hamilton KE.

Am J Physiol Gastrointest Liver Physiol. 2019 Jan 1;316(1):G197-G204. doi: 10.1152/ajpgi.00403.2017. Epub 2018 Dec 6.

PMID:
30520692
9.

Potential bio-protective effect of copper compounds: mimicking SOD and peroxidases enzymes and inhibiting acid phosphatase as a target for anti-osteoporotic chemotherapeutics.

Martini N, Parente JE, D Alessandro F, Rey M, Rizzi A, Williams PAM, Ferrer EG.

Mol Biol Rep. 2018 Dec 1. doi: 10.1007/s11033-018-4542-8. [Epub ahead of print]

PMID:
30506507
10.

A vector holographic optical trap.

Bhebhe N, Williams PAC, Rosales-Guzmán C, Rodriguez-Fajardo V, Forbes A.

Sci Rep. 2018 Nov 26;8(1):17387. doi: 10.1038/s41598-018-35889-0.

11.

Digestion of the glycosaminoglycan extracellular matrix by chondroitinase ABC supports retinal ganglion cell dendritic preservation in a rodent model of experimental glaucoma.

Tribble JR, Williams PA, Caterson B, Sengpiel F, Morgan JE.

Mol Brain. 2018 Nov 21;11(1):69. doi: 10.1186/s13041-018-0412-5.

12.

Establishing the Transitory Existence of Amorphous Phases in Crystallization Pathways by the CLASSIC NMR Technique.

Hughes CE, Williams PA, Kariuki BM, Harris KDM.

Chemphyschem. 2018 Dec 19;19(24):3341-3345. doi: 10.1002/cphc.201800976. Epub 2018 Nov 7.

PMID:
30347124
13.

Changes in the Morphology of Hypoglossal Motor Neurons in the Brainstem of Developing Rats.

Williams PA, Bellinger DL, Wilson CG.

Anat Rec (Hoboken). 2018 Oct 12. doi: 10.1002/ar.23971. [Epub ahead of print]

PMID:
30312533
14.

Synthesis of cationic alkylated chitosans and an investigation of their rheological properties and interaction with anionic surfactant.

Burr SJ, Williams PA, Ratcliffe I.

Carbohydr Polym. 2018 Dec 1;201:615-623. doi: 10.1016/j.carbpol.2018.08.105. Epub 2018 Aug 28.

PMID:
30241861
15.

A Fragment-Derived Clinical Candidate for Antagonism of X-Linked and Cellular Inhibitor of Apoptosis Proteins: 1-(6-[(4-Fluorophenyl)methyl]-5-(hydroxymethyl)-3,3-dimethyl-1 H,2 H,3 H-pyrrolo[3,2- b]pyridin-1-yl)-2-[(2 R,5 R)-5-methyl-2-([(3R)-3-methylmorpholin-4-yl]methyl)piperazin-1-yl]ethan-1-one (ASTX660).

Johnson CN, Ahn JS, Buck IM, Chiarparin E, Day JEH, Hopkins A, Howard S, Lewis EJ, Martins V, Millemaggi A, Munck JM, Page LW, Peakman T, Reader M, Rich SJ, Saxty G, Smyth T, Thompson NT, Ward GA, Williams PA, Wilsher NE, Chessari G.

J Med Chem. 2018 Aug 23;61(16):7314-7329. doi: 10.1021/acs.jmedchem.8b00900. Epub 2018 Aug 9.

PMID:
30091600
16.

Modeling hypoglossal motoneurons in the developing rat.

Williams PA, Dalton C, Wilson CG.

Respir Physiol Neurobiol. 2018 Jul 26. pii: S1569-9048(18)30110-1. doi: 10.1016/j.resp.2018.07.009. [Epub ahead of print]

PMID:
30056243
17.

Implementing a STEMI system of care in urban Bangalore: Rationale and Study Design for heart rescue India.

Ramesh A, LaBresh KA, Begeman R, Bobrow B, Campbell T, Chaudhury N, Edison M, Erickson TB, Manning JD, Prabhakar BS, Kotini-Shah P, Shetty N, Williams PA, Vanden Hoek T.

Contemp Clin Trials Commun. 2018 Apr 5;10:105-110. doi: 10.1016/j.conctc.2018.04.002. eCollection 2018 Jun.

18.

Jnk2 deficiency increases the rate of glaucomatous neurodegeneration in ocular hypertensive DBA/2J mice.

Harder JM, Williams PA, Soto I, Foxworth NE, Fernandes KA, Freeburg NF, Libby RT, John SWM.

Cell Death Dis. 2018 Jun 13;9(6):705. doi: 10.1038/s41419-018-0705-8.

19.

A multiethnic genome-wide association study of primary open-angle glaucoma identifies novel risk loci.

Choquet H, Paylakhi S, Kneeland SC, Thai KK, Hoffmann TJ, Yin J, Kvale MN, Banda Y, Tolman NG, Williams PA, Schaefer C, Melles RB, Risch N, John SWM, Nair KS, Jorgenson E.

Nat Commun. 2018 Jun 11;9(1):2278. doi: 10.1038/s41467-018-04555-4.

20.

Survey of Afterschool Programs Suggests Most Offer Fruit and Vegetables Daily.

Wiecha JL, Williams PA, Giombi KC, Richer A, Hall G.

Prev Chronic Dis. 2018 May 31;15:E68. doi: 10.5888/pcd15.170396.

21.

The interfacial, emulsification and encapsulation properties of hydrophobically modified inulin.

Kokubun S, Ratcliffe I, Williams PA.

Carbohydr Polym. 2018 Aug 15;194:18-23. doi: 10.1016/j.carbpol.2018.04.018. Epub 2018 Apr 5.

PMID:
29801827
22.

Relationships Between Theoretically Derived Short-Term Outcomes and Support for Policy Among the Public and Decision-Makers.

Schmitt CL, Curry L, Boudewyns V, Williams PA, Glasgow L, Van Hersh D, Willett J, Rogers T.

Prev Chronic Dis. 2018 May 17;15:E57. doi: 10.5888/pcd15.170288.

23.

ASTX660, a Novel Non-peptidomimetic Antagonist of cIAP1/2 and XIAP, Potently Induces TNFα-Dependent Apoptosis in Cancer Cell Lines and Inhibits Tumor Growth.

Ward GA, Lewis EJ, Ahn JS, Johnson CN, Lyons JF, Martins V, Munck JM, Rich SJ, Smyth T, Thompson NT, Williams PA, Wilsher NE, Wallis NG, Chessari G.

Mol Cancer Ther. 2018 Jul;17(7):1381-1391. doi: 10.1158/1535-7163.MCT-17-0848. Epub 2018 Apr 25.

PMID:
29695633
24.

Interaction of Zn with Losartan. Activation of Intrinsic Apoptotic Signaling Pathway in Lung Cancer Cells and Effects on Alkaline and Acid Phosphatases.

Martínez VR, Aguirre MV, Todaro JS, Piro OE, Echeverría GA, Naso LG, Ferrer EG, Williams PAM.

Biol Trace Elem Res. 2018 Dec;186(2):413-429. doi: 10.1007/s12011-018-1334-x. Epub 2018 Apr 12.

PMID:
29651733
25.

Insights into the Crystallization and Structural Evolution of Glycine Dihydrate by In Situ Solid-State NMR Spectroscopy.

Cerreia Vioglio P, Mollica G, Juramy M, Hughes CE, Williams PA, Ziarelli F, Viel S, Thureau P, Harris KDM.

Angew Chem Int Ed Engl. 2018 May 28;57(22):6619-6623. doi: 10.1002/anie.201801114. Epub 2018 May 8.

PMID:
29633439
26.

Comparisons of the spectroscopic and microbiological activities among coumarin-3-carboxylate, o-phenanthroline and zinc(II) complexes.

Islas MS, Martínez Medina JJ, Piro OE, Echeverría GA, Ferrer EG, Williams PAM.

Spectrochim Acta A Mol Biomol Spectrosc. 2018 Jun 5;198:212-221. doi: 10.1016/j.saa.2018.03.003. Epub 2018 Mar 7.

PMID:
29547823
27.

Nicotinamide treatment robustly protects from inherited mouse glaucoma.

Williams PA, Harder JM, Cardozo BH, Foxworth NE, John SWM.

Commun Integr Biol. 2018 Jan 19;11(1):e1356956. doi: 10.1080/19420889.2017.1356956. eCollection 2018.

28.

Exploring the Binding of Barbital to a Synthetic Macrocyclic Receptor. A Charge Density Study.

Du JJ, Hanrahan JR, Solomon VR, Williams PA, Groundwater PW, Overgaard J, Platts JA, Hibbs DE.

J Phys Chem A. 2018 Mar 22;122(11):3031-3044. doi: 10.1021/acs.jpca.7b11674. Epub 2018 Mar 13.

PMID:
29481082
29.

Development of a Radiation Oncology Resident Continuity Clinic to Improve Clinical Competency and Patient Compliance.

Yoo SK, Bian SX, Lin E, Batth SS, Ng LW, Andrade J, Williams PA, Pham AH, Ragab OM, Schechter NR, Chang EL, Jennelle RLS.

Int J Radiat Oncol Biol Phys. 2018 Mar 1;100(3):551-555. doi: 10.1016/j.ijrobp.2017.11.034. Epub 2017 Nov 27. No abstract available.

PMID:
29413269
30.
31.

Azilsartan and its Zn(II) complex. Synthesis, anticancer mechanisms of action and binding to bovine serum albumin.

Martínez VR, Aguirre MV, Todaro JS, Piro OE, Echeverría GA, Ferrer EG, Williams PAM.

Toxicol In Vitro. 2018 Apr;48:205-220. doi: 10.1016/j.tiv.2018.01.009.

PMID:
29408668
32.

Public and Opinion Leader Willingness to Fund Obesity-Focused Policies in Kansas.

Schmitt CL, Curry LE, Homsi G, Williams PA, Glasgow LM, Van Hersh D, Willett J, Rogers T.

Policy Polit Nurs Pract. 2017 Aug;18(3):125-134. doi: 10.1177/1527154417749492. Epub 2018 Jan 7.

PMID:
29307251
33.

Acceptance in the End of Life.

Williams PA.

JAMA Oncol. 2018 Jul 1;4(7):917-918. doi: 10.1001/jamaoncol.2017.4516. No abstract available.

PMID:
29302690
34.

Health Smart Homes: New Challenges.

Maeder AJ, Williams PAH.

Stud Health Technol Inform. 2017;245:166-169.

PMID:
29295074
35.

Onsite multikilowatt laser power meter calibration using radiation pressure.

Williams PA, Hadler JA, Simonds BJ, Lehman JH.

Appl Opt. 2017 Dec 1;56(34):9596-9600. doi: 10.1364/AO.56.009596.

PMID:
29216078
36.

Synthesis, characterisation and physicochemical properties of hydrophobically modified inulin using long-chain fatty acyl chlorides.

Han L, Ratcliffe I, Williams PA.

Carbohydr Polym. 2017 Dec 15;178:141-146. doi: 10.1016/j.carbpol.2017.09.008. Epub 2017 Sep 6.

PMID:
29050579
37.

Synthesis, characterization and biological studies of a cobalt(III) complex of sulfathiazole.

Pontoriero A, Mosconi N, Monti L, Bellú S, Williams PAM, Raimondi M, Lima B, Feresin GE, Nerli B, Rizzotto M.

Chem Biol Interact. 2017 Dec 25;278:152-161. doi: 10.1016/j.cbi.2017.10.004. Epub 2017 Oct 5.

PMID:
28987326
38.

Ab initio random structure searching of organic molecular solids: assessment and validation against experimental data.

Zilka M, Dudenko DV, Hughes CE, Williams PA, Sturniolo S, Franks WT, Pickard CJ, Yates JR, Harris KDM, Brown SP.

Phys Chem Chem Phys. 2017 Oct 4;19(38):25949-25960. doi: 10.1039/c7cp04186a.

39.

Alginate hydrogels of varied molecular weight distribution enable sustained release of sphingosine-1-phosphate and promote angiogenesis.

Williams PA, Campbell KT, Silva EA.

J Biomed Mater Res A. 2018 Jan;106(1):138-146. doi: 10.1002/jbm.a.36217. Epub 2017 Sep 26.

PMID:
28875559
40.

Glaucoma as a Metabolic Optic Neuropathy: Making the Case for Nicotinamide Treatment in Glaucoma.

Williams PA, Harder JM, John SWM.

J Glaucoma. 2017 Dec;26(12):1161-1168. doi: 10.1097/IJG.0000000000000767. Review.

41.

Consumer Perspectives on MyHealth Record: A Review.

Van Kasteren Y, Maeder A, Williams PA, Damarell R.

Stud Health Technol Inform. 2017;239:146-152. Review.

PMID:
28756450
42.

Theoretical investigation of the conformational space of baicalin.

Martínez Medina JJ, Ferrer EG, Williams PAM, Okulik NB.

J Mol Graph Model. 2017 Sep;76:181-191. doi: 10.1016/j.jmgm.2017.07.007. Epub 2017 Jul 11.

PMID:
28734206
43.

Evidence of promising biological-pharmacological activities of the sertraline-based copper complex: (SerH2)2[CuCl4].

Martini N, Parente JE, Toledo ME, Escudero GE, Laino CH, Martínez Medina JJ, Echeverría GA, Piro OE, Lezama L, Williams PAM, Ferrer EG.

J Inorg Biochem. 2017 Sep;174:76-89. doi: 10.1016/j.jinorgbio.2017.05.012. Epub 2017 Jun 1.

PMID:
28622579
44.
45.

Discovery of a Potent Nonpeptidomimetic, Small-Molecule Antagonist of Cellular Inhibitor of Apoptosis Protein 1 (cIAP1) and X-Linked Inhibitor of Apoptosis Protein (XIAP).

Tamanini E, Buck IM, Chessari G, Chiarparin E, Day JEH, Frederickson M, Griffiths-Jones CM, Hearn K, Heightman TD, Iqbal A, Johnson CN, Lewis EJ, Martins V, Peakman T, Reader M, Rich SJ, Ward GA, Williams PA, Wilsher NE.

J Med Chem. 2017 Jun 8;60(11):4611-4625. doi: 10.1021/acs.jmedchem.6b01877. Epub 2017 May 24.

PMID:
28492317
46.

Nicotinamide and WLDS Act Together to Prevent Neurodegeneration in Glaucoma.

Williams PA, Harder JM, Foxworth NE, Cardozo BH, Cochran KE, John SWM.

Front Neurosci. 2017 Apr 25;11:232. doi: 10.3389/fnins.2017.00232. eCollection 2017.

47.

Early immune responses are independent of RGC dysfunction in glaucoma with complement component C3 being protective.

Harder JM, Braine CE, Williams PA, Zhu X, MacNicoll KH, Sousa GL, Buchanan RA, Smith RS, Libby RT, Howell GR, John SWM.

Proc Natl Acad Sci U S A. 2017 May 9;114(19):E3839-E3848. doi: 10.1073/pnas.1608769114. Epub 2017 Apr 26.

48.

GlyCAM1 negatively regulates monocyte entry into the optic nerve head and contributes to radiation-based protection in glaucoma.

Williams PA, Braine CE, Foxworth NE, Cochran KE, John SWM.

J Neuroinflammation. 2017 Apr 26;14(1):93. doi: 10.1186/s12974-017-0868-8.

49.

Identifying Emerging Trends in Medical Informatics: A Synthesis Approach.

Van Kasteren Y, Williams PAH, Maeder A.

Stud Health Technol Inform. 2017;235:506-510.

PMID:
28423844
50.

Characterisation and solution properties of a galactomannan from Bauhinia monandra seeds.

Nwokocha LM, Senan C, Williams PA, Yadav MP.

Int J Biol Macromol. 2017 Aug;101:904-909. doi: 10.1016/j.ijbiomac.2017.03.105. Epub 2017 Mar 27.

PMID:
28359894

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