Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 354

1.

Design and Synthesis of TASIN Analogues Specifically Targeting Colorectal Cancer Cell Lines with Mutant Adenomatous Polyposis Coli (APC).

Wang W, Zhang L, Morlock L, Williams NS, Shay JW, De Brabander JK.

J Med Chem. 2019 May 23;62(10):5217-5241. doi: 10.1021/acs.jmedchem.9b00532. Epub 2019 May 9.

PMID:
31070915
2.

Best Mode of Delivery for Fetal Life-Limiting Conditions.

Cooper S, Williams NS.

Obstet Gynecol. 2019 Feb;133(2):368-371. doi: 10.1097/AOG.0000000000003065.

PMID:
30633136
3.

NQO1-dependent, Tumor-selective Radiosensitization of Non-small Cell Lung Cancers.

Motea EA, Huang X, Singh N, Kilgore JA, Williams NS, Xie XJ, Gerber DE, Beg MS, Bey EA, Boothman DA.

Clin Cancer Res. 2019 Apr 15;25(8):2601-2609. doi: 10.1158/1078-0432.CCR-18-2560. Epub 2019 Jan 7.

PMID:
30617135
4.

Targeting NAD+ Metabolism to Enhance Radiation Therapy Responses.

Lewis JE, Singh N, Holmila RJ, Sumer BD, Williams NS, Furdui CM, Kemp ML, Boothman DA.

Semin Radiat Oncol. 2019 Jan;29(1):6-15. doi: 10.1016/j.semradonc.2018.10.009. Review.

PMID:
30573185
5.

Reply letter to: A letter to the editor on "Anterior perineal plane for ultra-low anterior resection of the rectum (APPEAR) technique: A systematic review".

Lynes K, Williams NS, Chan CL, Thaha MA.

Int J Surg. 2019 Feb;62:87. doi: 10.1016/j.ijsu.2018.12.005. Epub 2018 Dec 13. No abstract available.

PMID:
30554007
6.

Longer heating duration increases localized doxorubicin deposition and therapeutic index in Vx2 tumors using MR-HIFU mild hyperthermia and thermosensitive liposomal doxorubicin.

Bing C, Patel P, Staruch RM, Shaikh S, Nofiele J, Wodzak Staruch M, Szczepanski D, Williams NS, Laetsch T, Chopra R.

Int J Hyperthermia. 2019;36(1):196-203. doi: 10.1080/02656736.2018.1550815. Epub 2018 Dec 12.

PMID:
30541350
7.

Green roof storage capacity can be more important than evapotranspiration for retention performance.

Zhang Z, Szota C, Fletcher TD, Williams NSG, Farrell C.

J Environ Manage. 2019 Feb 15;232:404-412. doi: 10.1016/j.jenvman.2018.11.070. Epub 2018 Nov 27.

PMID:
30500704
8.

Neuroprotective efficacy of P7C3 compounds in primate hippocampus.

Bauman MD, Schumann CM, Carlson EL, Taylor SL, Vázquez-Rosa E, Cintrón-Pérez CJ, Shin MK, Williams NS, Pieper AA.

Transl Psychiatry. 2018 Sep 26;8(1):202. doi: 10.1038/s41398-018-0244-1.

9.

Correcting common misconceptions to inspire conservation action in urban environments.

Soanes K, Sievers M, Chee YE, Williams NSG, Bhardwaj M, Marshall AJ, Parris KM.

Conserv Biol. 2019 Apr;33(2):300-306. doi: 10.1111/cobi.13193. Epub 2018 Oct 24.

PMID:
30022525
10.

Discovery of Cytochrome P450 4F11 Activated Inhibitors of Stearoyl Coenzyme A Desaturase.

Winterton SE, Capota E, Wang X, Chen H, Mallipeddi PL, Williams NS, Posner BA, Nijhawan D, Ready JM.

J Med Chem. 2018 Jun 28;61(12):5199-5221. doi: 10.1021/acs.jmedchem.8b00052. Epub 2018 Jun 19.

11.

Chemistry-First Approach for Nomination of Personalized Treatment in Lung Cancer.

McMillan EA, Ryu MJ, Diep CH, Mendiratta S, Clemenceau JR, Vaden RM, Kim JH, Motoyaji T, Covington KR, Peyton M, Huffman K, Wu X, Girard L, Sung Y, Chen PH, Mallipeddi PL, Lee JY, Hanson J, Voruganti S, Yu Y, Park S, Sudderth J, DeSevo C, Muzny DM, Doddapaneni H, Gazdar A, Gibbs RA, Hwang TH, Heymach JV, Wistuba I, Coombes KR, Williams NS, Wheeler DA, MacMillan JB, Deberardinis RJ, Roth MG, Posner BA, Minna JD, Kim HS, White MA.

Cell. 2018 May 3;173(4):864-878.e29. doi: 10.1016/j.cell.2018.03.028. Epub 2018 Apr 19.

12.

Targeted inhibitors of P-glycoprotein increase chemotherapeutic-induced mortality of multidrug resistant tumor cells.

Nanayakkara AK, Follit CA, Chen G, Williams NS, Vogel PD, Wise JG.

Sci Rep. 2018 Jan 17;8(1):967. doi: 10.1038/s41598-018-19325-x.

13.

Influence of plant composition and water use strategies on green roof stormwater retention.

Zhang Z, Szota C, Fletcher TD, Williams NSG, Werdin J, Farrell C.

Sci Total Environ. 2018 Jun 1;625:775-781. doi: 10.1016/j.scitotenv.2017.12.231. Epub 2018 Jan 3.

PMID:
29306165
14.

(-)-P7C3-S243 Protects a Rat Model of Alzheimer's Disease From Neuropsychiatric Deficits and Neurodegeneration Without Altering Amyloid Deposition or Reactive Glia.

Voorhees JR, Remy MT, Cintrón-Pérez CJ, El Rassi E, Khan MZ, Dutca LM, Yin TC, McDaniel LN, Williams NS, Brat DJ, Pieper AA.

Biol Psychiatry. 2018 Oct 1;84(7):488-498. doi: 10.1016/j.biopsych.2017.10.023. Epub 2017 Nov 6.

15.

Implementation of a Web-Based Organ Donation Educational Intervention: Development and Use of a Refined Process Evaluation Model.

Redmond N, Harker L, Bamps Y, Flemming SSC, Perryman JP, Thompson NJ, Patzer RE, Williams NSD, Arriola KRJ.

J Med Internet Res. 2017 Nov 30;19(11):e396. doi: 10.2196/jmir.8501.

16.

How do associative and phonemic overlap interact to boost illusory recollection?

Hutchison KA, Meade ML, Williams NS, Manley KD, McNabb JC.

Memory. 2018 May;26(5):664-671. doi: 10.1080/09658211.2017.1393091. Epub 2017 Oct 24.

PMID:
29065777
17.

Drought-avoiding plants with low water use can achieve high rainfall retention without jeopardising survival on green roofs.

Szota C, Farrell C, Williams NSG, Arndt SK, Fletcher TD.

Sci Total Environ. 2017 Dec 15;603-604:340-351. doi: 10.1016/j.scitotenv.2017.06.061. Epub 2017 Jun 23.

PMID:
28633111
18.

Biomarker Accessible and Chemically Addressable Mechanistic Subtypes of BRAF Melanoma.

Eskiocak B, McMillan EA, Mendiratta S, Kollipara RK, Zhang H, Humphries CG, Wang C, Garcia-Rodriguez J, Ding M, Zaman A, Rosales TI, Eskiocak U, Smith MP, Sudderth J, Komurov K, Deberardinis RJ, Wellbrock C, Davies MA, Wargo JA, Yu Y, De Brabander JK, Williams NS, Chin L, Rizos H, Long GV, Kittler R, White MA.

Cancer Discov. 2017 Aug;7(8):832-851. doi: 10.1158/2159-8290.CD-16-0955. Epub 2017 Apr 28.

19.

Inhibitors of 15-Prostaglandin Dehydrogenase To Potentiate Tissue Repair.

Antczak MI, Zhang Y, Wang C, Doran J, Naidoo J, Voruganti S, Williams NS, Markowitz SD, Ready JM.

J Med Chem. 2017 May 11;60(9):3979-4001. doi: 10.1021/acs.jmedchem.7b00271. Epub 2017 Apr 25.

20.

Topoisomerase II Inhibitors Induce DNA Damage-Dependent Interferon Responses Circumventing Ebola Virus Immune Evasion.

Luthra P, Aguirre S, Yen BC, Pietzsch CA, Sanchez-Aparicio MT, Tigabu B, Morlock LK, García-Sastre A, Leung DW, Williams NS, Fernandez-Sesma A, Bukreyev A, Basler CF.

MBio. 2017 Apr 4;8(2). pii: e00368-17. doi: 10.1128/mBio.00368-17.

21.

Safety, tolerability, pharmacokinetics, and activity of the novel long-acting antimalarial DSM265: a two-part first-in-human phase 1a/1b randomised study.

McCarthy JS, Lotharius J, Rückle T, Chalon S, Phillips MA, Elliott S, Sekuloski S, Griffin P, Ng CL, Fidock DA, Marquart L, Williams NS, Gobeau N, Bebrevska L, Rosario M, Marsh K, Möhrle JJ.

Lancet Infect Dis. 2017 Jun;17(6):626-635. doi: 10.1016/S1473-3099(17)30171-8. Epub 2017 Mar 28.

22.

Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.

Han T, Goralski M, Gaskill N, Capota E, Kim J, Ting TC, Xie Y, Williams NS, Nijhawan D.

Science. 2017 Apr 28;356(6336). pii: eaal3755. doi: 10.1126/science.aal3755. Epub 2017 Mar 16. Erratum in: Science. 2017 May 26;356(6340):null.

PMID:
28302793
23.

Effect of Monomer Solubility on the Evolution of Copolymer Morphology during Polymerization-Induced Self-Assembly in Aqueous Solution.

Cockram AA, Neal TJ, Derry MJ, Mykhaylyk OO, Williams NS, Murray MW, Emmett SN, Armes SP.

Macromolecules. 2017 Feb 14;50(3):796-802. doi: 10.1021/acs.macromol.6b02309. Epub 2017 Jan 26.

24.

Blockade to pathological remodeling of infarcted heart tissue using a porcupine antagonist.

Moon J, Zhou H, Zhang LS, Tan W, Liu Y, Zhang S, Morlock LK, Bao X, Palecek SP, Feng JQ, Williams NS, Amatruda JF, Olson EN, Bassel-Duby R, Lum L.

Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):1649-1654. doi: 10.1073/pnas.1621346114. Epub 2017 Jan 31.

25.

Conserving herbivorous and predatory insects in urban green spaces.

Mata L, Threlfall CG, Williams NS, Hahs AK, Malipatil M, Stork NE, Livesley SJ.

Sci Rep. 2017 Jan 19;7:40970. doi: 10.1038/srep40970.

26.

Development of Dihydroxyphenyl Sulfonylisoindoline Derivatives as Liver-Targeting Pyruvate Dehydrogenase Kinase Inhibitors.

Tso SC, Lou M, Wu CY, Gui WJ, Chuang JL, Morlock LK, Williams NS, Wynn RM, Qi X, Chuang DT.

J Med Chem. 2017 Feb 9;60(3):1142-1150. doi: 10.1021/acs.jmedchem.6b01540. Epub 2017 Jan 31.

27.

Leveraging an NQO1 Bioactivatable Drug for Tumor-Selective Use of Poly(ADP-ribose) Polymerase Inhibitors.

Huang X, Motea EA, Moore ZR, Yao J, Dong Y, Chakrabarti G, Kilgore JA, Silvers MA, Patidar PL, Cholka A, Fattah F, Cha Y, Anderson GG, Kusko R, Peyton M, Yan J, Xie XJ, Sarode V, Williams NS, Minna JD, Beg M, Gerber DE, Bey EA, Boothman DA.

Cancer Cell. 2016 Dec 12;30(6):940-952. doi: 10.1016/j.ccell.2016.11.006.

28.

Development of a triazole class of highly potent Porcn inhibitors.

You L, Zhang C, Yarravarapu N, Morlock L, Wang X, Zhang L, Williams NS, Lum L, Chen C.

Bioorg Med Chem Lett. 2016 Dec 15;26(24):5891-5895. doi: 10.1016/j.bmcl.2016.11.012. Epub 2016 Nov 11.

29.

Hierarchical filters determine community assembly of urban species pools.

Aronson MF, Nilon CH, Lepczyk CA, Parker TS, Warren PS, Cilliers SS, Goddard MA, Hahs AK, Herzog C, Katti M, La Sorte FA, Williams NS, Zipperer W.

Ecology. 2016 Nov;97(11):2952-2963. doi: 10.1002/ecy.1535.

30.

Selective targeting of mutant adenomatous polyposis coli (APC) in colorectal cancer.

Zhang L, Theodoropoulos PC, Eskiocak U, Wang W, Moon YA, Posner B, Williams NS, Wright WE, Kim SB, Nijhawan D, De Brabander JK, Shay JW.

Sci Transl Med. 2016 Oct 19;8(361):361ra140.

PMID:
27798265
31.

Anterior Perineal PlanE for ultra-low Anterior Resection of the rectum (APPEAR) technique: A systematic review.

Lynes K, Williams NS, Chan CL, Thaha MA.

Int J Surg. 2016 Sep;33 Pt A:117-23. doi: 10.1016/j.ijsu.2016.07.075. Epub 2016 Aug 5. Review.

32.

Discovery of tumor-specific irreversible inhibitors of stearoyl CoA desaturase.

Theodoropoulos PC, Gonzales SS, Winterton SE, Rodriguez-Navas C, McKnight JS, Morlock LK, Hanson JM, Cross B, Owen AE, Duan Y, Moreno JR, Lemoff A, Mirzaei H, Posner BA, Williams NS, Ready JM, Nijhawan D.

Nat Chem Biol. 2016 Apr;12(4):218-25. doi: 10.1038/nchembio.2016. Epub 2016 Feb 1.

33.

Soil Carbon and Carbon/Nitrogen Ratio Change under Tree Canopy, Tall Grass, and Turf Grass Areas of Urban Green Space.

Livesley SJ, Ossola A, Threlfall CG, Hahs AK, Williams NS.

J Environ Qual. 2016 Jan;45(1):215-23. doi: 10.2134/jeq2015.03.0121.

PMID:
26828177
34.

Posaconazole, a Second-Generation Triazole Antifungal Drug, Inhibits the Hedgehog Signaling Pathway and Progression of Basal Cell Carcinoma.

Chen B, Trang V, Lee A, Williams NS, Wilson AN, Epstein EH Jr, Tang JY, Kim J.

Mol Cancer Ther. 2016 May;15(5):866-76. doi: 10.1158/1535-7163.MCT-15-0729-T. Epub 2016 Jan 28.

35.

When should surgeons retire? (Br J Surg 2016: 103: 35-42).

Williams NS.

Br J Surg. 2016 Jan;103(1):42-3. doi: 10.1002/bjs.10042. No abstract available.

PMID:
26768098
36.

High-throughput simultaneous screen and counterscreen identifies homoharringtonine as synthetic lethal with von Hippel-Lindau loss in renal cell carcinoma.

Wolff NC, Pavía-Jiménez A, Tcheuyap VT, Alexander S, Vishwanath M, Christie A, Xie XJ, Williams NS, Kapur P, Posner B, McKay RM, Brugarolas J.

Oncotarget. 2015 Jul 10;6(19):16951-62.

37.

Identification of CREB3L1 as a Biomarker Predicting Doxorubicin Treatment Outcome.

Denard B, Pavia-Jimenez A, Chen W, Williams NS, Naina H, Collins R, Brugarolas J, Ye J.

PLoS One. 2015 Jun 25;10(6):e0129233. doi: 10.1371/journal.pone.0129233. eCollection 2015.

38.

TISSUE REGENERATION. Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration.

Zhang Y, Desai A, Yang SY, Bae KB, Antczak MI, Fink SP, Tiwari S, Willis JE, Williams NS, Dawson DM, Wald D, Chen WD, Wang Z, Kasturi L, Larusch GA, He L, Cominelli F, Di Martino L, Djuric Z, Milne GL, Chance M, Sanabria J, Dealwis C, Mikkola D, Naidoo J, Wei S, Tai HH, Gerson SL, Ready JM, Posner B, Willson JK, Markowitz SD.

Science. 2015 Jun 12;348(6240):aaa2340. doi: 10.1126/science.aaa2340.

39.

The Hedgehog Pathway Effector Smoothened Exhibits Signaling Competency in the Absence of Ciliary Accumulation.

Fan CW, Chen B, Franco I, Lu J, Shi H, Wei S, Wang C, Wu X, Tang W, Roth MG, Williams NS, Hirsch E, Chen C, Lum L.

Chem Biol. 2015 Apr 23;22(4):559. doi: 10.1016/j.chembiol.2015.04.001. Epub 2015 Apr 23. No abstract available.

40.

Occupational vaccination of health care workers: uptake, attitudes and potential solutions.

Little KE, Goodridge S, Lewis H, Lingard SW, Din S, Tidley M, Roberts RJ, Williams NS, Hayes S.

Public Health. 2015 Jun;129(6):755-62. doi: 10.1016/j.puhe.2015.02.031. Epub 2015 Mar 31.

PMID:
25834928
41.

A case-controlled pilot study assessing the safety and efficacy of the Stapled Mesh stomA Reinforcement Technique (SMART) in reducing the incidence of parastomal herniation.

Williams NS, Hotouras A, Bhan C, Murphy J, Chan CL.

Hernia. 2015 Dec;19(6):949-54. doi: 10.1007/s10029-015-1346-9. Epub 2015 Feb 3.

PMID:
25644485
42.

Randomized clinical trial of sacral versus percutaneous tibial nerve stimulation in patients with faecal incontinence.

Thin NN, Taylor SJ, Bremner SA, Emmanuel AV, Hounsome N, Williams NS, Knowles CH; Neuromodulation Trial Study Group.

Br J Surg. 2015 Mar;102(4):349-58. doi: 10.1002/bjs.9695. Epub 2015 Jan 28.

PMID:
25644291
43.

Protective efficacy of P7C3-S243 in the 6-hydroxydopamine model of Parkinson's disease.

De Jesús-Cortés H, Miller AD, Britt JK, DeMarco AJ, De Jesús-Cortés M, Stuebing E, Naidoo J, Vázquez-Rosa E, Morlock L, Williams NS, Ready JM, Narayanan NS, Pieper AA.

NPJ Parkinsons Dis. 2015;1. pii: 15010. Epub 2015 May 21.

44.

Esterase-activatable β-lapachone prodrug micelles for NQO1-targeted lung cancer therapy.

Ma X, Huang X, Moore Z, Huang G, Kilgore JA, Wang Y, Hammer S, Williams NS, Boothman DA, Gao J.

J Control Release. 2015 Feb 28;200:201-11. doi: 10.1016/j.jconrel.2014.12.027. Epub 2014 Dec 24.

45.

Diet-induced unresolved ER stress hinders KRAS-driven lung tumorigenesis.

Ramadori G, Konstantinidou G, Venkateswaran N, Biscotti T, Morlock L, Galié M, Williams NS, Luchetti M, Santinelli A, Scaglioni PP, Coppari R.

Cell Metab. 2015 Jan 6;21(1):117-25. doi: 10.1016/j.cmet.2014.11.020. Epub 2014 Dec 18.

46.

The Hedgehog pathway effector smoothened exhibits signaling competency in the absence of ciliary accumulation.

Fan CW, Chen B, Franco I, Lu J, Shi H, Wei S, Wang C, Wu X, Tang W, Roth MG, Williams NS, Hirsch E, Chen C, Lum L.

Chem Biol. 2014 Dec 18;21(12):1680-9. doi: 10.1016/j.chembiol.2014.10.013. Epub 2014 Dec 4. Erratum in: Chem Biol. 2015 Apr 23;22(4):559.

47.

Current aspects and future prospects of total anorectal reconstruction--a critical and comprehensive review of the literature.

Inglin RA, Eberli D, Brügger LE, Sulser T, Williams NS, Candinas D.

Int J Colorectal Dis. 2015 Mar;30(3):293-302. doi: 10.1007/s00384-014-2065-x. Epub 2014 Nov 19. Review.

PMID:
25403563
48.

QseC inhibitors as an antivirulence approach for Gram-negative pathogens.

Curtis MM, Russell R, Moreira CG, Adebesin AM, Wang C, Williams NS, Taussig R, Stewart D, Zimmern P, Lu B, Prasad RN, Zhu C, Rasko DA, Huntley JF, Falck JR, Sperandio V.

MBio. 2014 Nov 11;5(6):e02165. doi: 10.1128/mBio.02165-14.

49.

Parastomal hernia prevention: is it all about mesh reinforcement?

Hotouras A, Bhan C, Murphy J, Chan CL, Williams NS.

Dis Colon Rectum. 2014 Dec;57(12):e443-4. doi: 10.1097/DCR.0000000000000255. No abstract available.

PMID:
25380015
50.

Pharmacologic rescue of motor and sensory function by the neuroprotective compound P7C3 following neonatal nerve injury.

Kemp SW, Szynkaruk M, Stanoulis KN, Wood MD, Liu EH, Willand MP, Morlock L, Naidoo J, Williams NS, Ready JM, Mangano TJ, Beggs S, Salter MW, Gordon T, Pieper AA, Borschel GH.

Neuroscience. 2015 Jan 22;284:202-16. doi: 10.1016/j.neuroscience.2014.10.005. Epub 2014 Oct 13.

PMID:
25313000

Supplemental Content

Loading ...
Support Center