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Items: 1 to 50 of 130

1.

Attenuation of antidepressant and antisuicidal effects of ketamine by opioid receptor antagonism.

Williams NR, Heifets BD, Bentzley BS, Blasey C, Sudheimer KD, Hawkins J, Lyons DM, Schatzberg AF.

Mol Psychiatry. 2019 Aug 29. doi: 10.1038/s41380-019-0503-4. [Epub ahead of print]

PMID:
31467392
2.

Defect segregation facilitates oxygen transport at fluorite UO2 grain boundaries.

Symington AR, Molinari M, Brincat NA, Williams NR, Parker SC.

Philos Trans A Math Phys Eng Sci. 2019 Aug 26;377(2152):20190026. doi: 10.1098/rsta.2019.0026. Epub 2019 Jul 8.

PMID:
31280720
3.

NeuroSAFE robot-assisted laparoscopic prostatectomy versus standard robot-assisted laparoscopic prostatectomy for men with localised prostate cancer (NeuroSAFE PROOF): protocol for a randomised controlled feasibility study.

Dinneen E, Haider A, Allen C, Freeman A, Briggs T, Nathan S, Brew-Graves C, Grierson J, Williams NR, Persad R, Oakley N, Adshead JM, Huland H, Haese A, Shaw G.

BMJ Open. 2019 Jun 11;9(6):e028132. doi: 10.1136/bmjopen-2018-028132.

4.

Multimodal characterization of the human nucleus accumbens.

Cartmell SC, Tian Q, Thio BJ, Leuze C, Ye L, Williams NR, Yang G, Ben-Dor G, Deisseroth K, Grill WM, McNab JA, Halpern CH.

Neuroimage. 2019 Sep;198:137-149. doi: 10.1016/j.neuroimage.2019.05.019. Epub 2019 May 8.

PMID:
31077843
5.

Rigorous Trial Design Is Essential to Understand the Role of Opioid Receptors in Ketamine's Antidepressant Effect.

Heifets BD, Williams NR, Bentzley BS, Schatzberg AF.

JAMA Psychiatry. 2019 Jun 1;76(6):657-658. doi: 10.1001/jamapsychiatry.2019.0766. No abstract available.

PMID:
31042274
6.

Rigorous Translational Models Are Key to Studying Ketamine's Antidepressant Mechanism: Response to Wang and Kaplin.

Heifets BD, Williams NR, Blasey C, Sudheimer K, Rodriguez CI, Schatzberg AF.

Am J Psychiatry. 2019 May 1;176(5):412. doi: 10.1176/appi.ajp.2019.19010044r. No abstract available.

PMID:
31039633
7.

Case Studies in Neuroscience: The electrophysiology of a human obsession in nucleus accumbens.

Miller KJ, Prieto T, Williams NR, Halpern CH.

J Neurophysiol. 2019 Jun 1;121(6):2336-2340. doi: 10.1152/jn.00096.2019. Epub 2019 Apr 24.

PMID:
31017846
8.

Robust clinical benefit of multi-target deep brain stimulation for treatment of Gilles de la Tourette syndrome and its comorbidities.

Kakusa B, Saluja S, Tate WJ, Espil FM, Halpern CH, Williams NR.

Brain Stimul. 2019 May - Jun;12(3):816-818. doi: 10.1016/j.brs.2019.02.026. Epub 2019 Mar 4. No abstract available.

PMID:
30878341
9.

Impact of Hydrogen on the Intermediate Oxygen Clusters and Diffusion in Fluorite Structured UO2+ x.

Flitcroft JM, Symington AR, Molinari M, Brincat NA, Williams NR, Parker SC.

Inorg Chem. 2019 Mar 18;58(6):3774-3779. doi: 10.1021/acs.inorgchem.8b03317. Epub 2019 Mar 5.

PMID:
30835457
10.

Interpreting Ketamine's Opioid Receptor Dependent Effect: Response to Sanacora.

Heifets BD, Williams NR, Blasey C, Sudheimer K, Rodriguez CI, Schatzberg AF.

Am J Psychiatry. 2019 Mar 1;176(3):249-250. doi: 10.1176/appi.ajp.2018.18091061r. No abstract available.

PMID:
30818991
11.

Target Population, Dose, and Timing Considerations for Understanding Naltrexone's Subjective Effect: Response to Amiaz.

Heifets BD, Williams NR, Blasey C, Sudheimer K, Rodriguez CI, Schatzberg AF.

Am J Psychiatry. 2019 Mar 1;176(3):251-252. doi: 10.1176/appi.ajp.2018.18111231r. No abstract available.

PMID:
30818989
12.

A medical device registry is long overdue.

Williams NR.

BMJ. 2019 Feb 7;364:l577. doi: 10.1136/bmj.l577. No abstract available.

PMID:
30733245
13.

Comparative effectiveness of neuroablation and deep brain stimulation for treatment-resistant obsessive-compulsive disorder: a meta-analytic study.

Kumar KK, Appelboom G, Lamsam L, Caplan AL, Williams NR, Bhati MT, Stein SC, Halpern CH.

J Neurol Neurosurg Psychiatry. 2019 Apr;90(4):469-473. doi: 10.1136/jnnp-2018-319318. Epub 2019 Jan 24.

PMID:
30679237
14.

Nonrigid reconstruction of 3D breast surfaces with a low-cost RGBD camera for surgical planning and aesthetic evaluation.

Lacher RM, Vasconcelos F, Williams NR, Rindermann G, Hipwell J, Hawkes D, Stoyanov D.

Med Image Anal. 2019 Apr;53:11-25. doi: 10.1016/j.media.2019.01.003. Epub 2019 Jan 11.

15.

Protocol for a feasibility randomised controlled trial of targeted oxygen therapy in mechanically ventilated critically ill patients.

Martin DS, Brew-Graves C, McCartan N, Jell G, Potyka I, Stevens J, Williams NR, McNeil M, O'Driscoll BR, Mythen M, Grocott MPW.

BMJ Open. 2019 Jan 17;9(1):e021674. doi: 10.1136/bmjopen-2018-021674.

16.

The SmartTarget Biopsy Trial: A Prospective, Within-person Randomised, Blinded Trial Comparing the Accuracy of Visual-registration and Magnetic Resonance Imaging/Ultrasound Image-fusion Targeted Biopsies for Prostate Cancer Risk Stratification.

Hamid S, Donaldson IA, Hu Y, Rodell R, Villarini B, Bonmati E, Tranter P, Punwani S, Sidhu HS, Willis S, van der Meulen J, Hawkes D, McCartan N, Potyka I, Williams NR, Brew-Graves C, Freeman A, Moore CM, Barratt D, Emberton M, Ahmed HU.

Eur Urol. 2019 May;75(5):733-740. doi: 10.1016/j.eururo.2018.08.007. Epub 2018 Dec 6.

17.

Recommendations for clinical translation of nanoparticle-enhanced radiotherapy.

Ricketts K, Ahmad R, Beaton L, Cousins B, Critchley K, Davies M, Evans S, Fenuyi I, Gavriilidis A, Harmer QJ, Jayne D, Jefford M, Loizidou M, Macrobert A, Moorcroft S, Naasani I, Ong ZY, Prise KM, Rannard S, Richards T, Schettino G, Sharma RA, Tillement O, Wakefield G, Williams NR, Yaghini E, Royle G.

Br J Radiol. 2018 Dec;91(1092):20180325. doi: 10.1259/bjr.20180325. Epub 2018 Sep 17.

18.

Attenuation of Antidepressant Effects of Ketamine by Opioid Receptor Antagonism.

Williams NR, Heifets BD, Blasey C, Sudheimer K, Pannu J, Pankow H, Hawkins J, Birnbaum J, Lyons DM, Rodriguez CI, Schatzberg AF.

Am J Psychiatry. 2018 Dec 1;175(12):1205-1215. doi: 10.1176/appi.ajp.2018.18020138. Epub 2018 Aug 29.

19.

Robot-assisted radical cystectomy with intracorporeal urinary diversion versus open radical cystectomy (iROC): protocol for a randomised controlled trial with internal feasibility study.

Catto JWF, Khetrapal P, Ambler G, Sarpong R, Khan MS, Tan M, Feber A, Dixon S, Goodwin L, Williams NR, McGrath J, Rowe E, Koupparis A, Brew-Graves C, Kelly JD.

BMJ Open. 2018 Aug 8;8(8):e020500. doi: 10.1136/bmjopen-2017-020500. Erratum in: BMJ Open. 2019 Aug 15;9(8):e020500corr1.

20.

Systematic review of the impact of breast-conserving surgery on cancer outcomes of multiple ipsilateral breast cancers.

Winters ZE, Horsnell J, Elvers KT, Maxwell AJ, Jones LJ, Shaaban AM, Schmid P, Williams NR, Beswick A, Greenwood R, Ingram JC, Saunders C, Vaidya JS, Esserman L, Jatoi I, Brunt AM.

BJS Open. 2018 May 22;2(4):162-174. doi: 10.1002/bjs5.53. eCollection 2018 Aug. Review.

21.

The value of 3D images in the aesthetic evaluation of breast cancer conservative treatment. Results from a prospective multicentric clinical trial.

Cardoso MJ, Vrieling C, Cardoso JS, Oliveira HP, Williams NR, Dixon JM; PICTURE Project Clinical Trial Team; PICTURE Project Delphi Panel.

Breast. 2018 Oct;41:19-24. doi: 10.1016/j.breast.2018.06.008. Epub 2018 Jun 18.

22.

Multidomain Quantitative Recovery Following Radical Cystectomy for Patients Within the Robot-assisted Radical Cystectomy with Intracorporeal Urinary Diversion Versus Open Radical Cystectomy Randomised Controlled Trial: The First 30 Patients.

Catto JWF, Khetrapal P, Ambler G, Sarpong R, Potyka I, Khan MS, Tan M, Feber A, Bourke L, Noon AP, Dixon S, Goodwin L, Williams NR, Rowe E, Kouparis A, McGrath J, Brew-Graves C, Kelly JD.

Eur Urol. 2018 Oct;74(4):531-534. doi: 10.1016/j.eururo.2018.05.008. Epub 2018 May 21. No abstract available.

PMID:
29793815
23.

Cosmetic outcome as rated by patients, doctors, nurses and BCCT.core software assessed over 5 years in a subset of patients in the TARGIT-A Trial.

Corica T, Nowak AK, Saunders CM, Bulsara MK, Taylor M, Williams NR, Keshtgar M, Joseph DJ, Vaidya JS.

Radiat Oncol. 2018 Apr 13;13(1):68. doi: 10.1186/s13014-018-0998-x.

24.

MRI-Targeted or Standard Biopsy for Prostate-Cancer Diagnosis.

Kasivisvanathan V, Rannikko AS, Borghi M, Panebianco V, Mynderse LA, Vaarala MH, Briganti A, Budäus L, Hellawell G, Hindley RG, Roobol MJ, Eggener S, Ghei M, Villers A, Bladou F, Villeirs GM, Virdi J, Boxler S, Robert G, Singh PB, Venderink W, Hadaschik BA, Ruffion A, Hu JC, Margolis D, Crouzet S, Klotz L, Taneja SS, Pinto P, Gill I, Allen C, Giganti F, Freeman A, Morris S, Punwani S, Williams NR, Brew-Graves C, Deeks J, Takwoingi Y, Emberton M, Moore CM; PRECISION Study Group Collaborators.

N Engl J Med. 2018 May 10;378(19):1767-1777. doi: 10.1056/NEJMoa1801993. Epub 2018 Mar 18.

25.

High-dose spaced theta-burst TMS as a rapid-acting antidepressant in highly refractory depression.

Williams NR, Sudheimer KD, Bentzley BS, Pannu J, Stimpson KH, Duvio D, Cherian K, Hawkins J, Scherrer KH, Vyssoki B, DeSouza D, Raj KS, Keller J, Schatzberg AF.

Brain. 2018 Mar 1;141(3):e18. doi: 10.1093/brain/awx379. No abstract available.

26.

Closing the loop on impulsivity via nucleus accumbens delta-band activity in mice and man.

Wu H, Miller KJ, Blumenfeld Z, Williams NR, Ravikumar VK, Lee KE, Kakusa B, Sacchet MD, Wintermark M, Christoffel DJ, Rutt BK, Bronte-Stewart H, Knutson B, Malenka RC, Halpern CH.

Proc Natl Acad Sci U S A. 2018 Jan 2;115(1):192-197. doi: 10.1073/pnas.1712214114. Epub 2017 Dec 18.

27.

Intraoperative prediction of the two axillary lymph node macrometastases threshold in patients with breast cancer using a one-step nucleic acid cytokeratin-19 amplification assay.

Fung V, Kohlhardt S, Vergani P, Zardin GJ, Williams NR.

Mol Clin Oncol. 2017 Nov;7(5):755-762. doi: 10.3892/mco.2017.1404. Epub 2017 Sep 1.

28.

DETECT I & DETECT II: a study protocol for a prospective multicentre observational study to validate the UroMark assay for the detection of bladder cancer from urinary cells.

Tan WS, Feber A, Dong L, Sarpong R, Rezaee S, Rodney S, Khetrapal P, de Winter P, Ocampo F, Jalil R, Williams NR, Brew-Graves C, Kelly JD.

BMC Cancer. 2017 Nov 15;17(1):767. doi: 10.1186/s12885-017-3758-7.

29.

Optimization of epidural cortical stimulation for treatment-resistant depression.

Williams NR, Bentzley BS, Hopkins T, Pannu J, Sahlem GL, Takacs I, George MS, Nahas Z, Short EB.

Brain Stimul. 2018 Jan - Feb;11(1):239-240. doi: 10.1016/j.brs.2017.09.001. Epub 2017 Sep 6. No abstract available.

PMID:
28918944
30.

The Landscape of Randomised Controlled Trials of Therapies in Breast Cancer in Low and Middle Income Countries.

Lynch-Kelly K, Singer M, Williams NR.

Int J Breast Cancer. 2017;2017:4259704. doi: 10.1155/2017/4259704. Epub 2017 Apr 9. Review.

31.

It takes time to tune.

Bentzley BS, Pannu J, Badran BW, Halpern CH, Williams NR.

Ann Transl Med. 2017 Apr;5(7):171. doi: 10.21037/atm.2017.03.49. No abstract available.

32.

Neuroversion: using electroconvulsive therapy as a bridge to deep brain stimulation implantation.

Williams NR, Sahlem G, Pannu J, Takacs I, Short B, Revuelta G, George MS.

Neurocase. 2017 Feb;23(1):26-30. doi: 10.1080/13554794.2016.1276605. Epub 2017 Feb 7.

PMID:
28376692
33.

Best available evidence related to clinical benefit of surgical resection in multimodality treatment of metastatic colorectal cancer indicates that a randomised controlled trial is warranted.

Treasure T, Williams NR.

Eur J Cancer. 2017 Apr;75:310-312. doi: 10.1016/j.ejca.2016.11.033. Epub 2017 Mar 1. No abstract available.

PMID:
28259014
34.

Sentinel node detection in early breast cancer with intraoperative portable gamma camera: UK experience.

Ghosh D, Michalopoulos NV, Davidson T, Wickham F, Williams NR, Keshtgar MR.

Breast. 2017 Apr;32:53-59. doi: 10.1016/j.breast.2016.12.013. Epub 2016 Dec 27.

35.

An international randomised controlled trial to compare TARGeted Intraoperative radioTherapy (TARGIT) with conventional postoperative radiotherapy after breast-conserving surgery for women with early-stage breast cancer (the TARGIT-A trial).

Vaidya JS, Wenz F, Bulsara M, Tobias JS, Joseph DJ, Saunders C, Brew-Graves C, Potyka I, Morris S, Vaidya HJ, Williams NR, Baum M.

Health Technol Assess. 2016 Sep;20(73):1-188.

36.

Intraoperative radiation therapy deserves to be made more readily available to patients.

Keshtgar M, Williams NR.

Chin J Cancer Res. 2016 Aug;28(4):461-2. doi: 10.21147/j.issn.1000-9604.2016.04.10. No abstract available.

37.

Meta-analysis of colorectal cancer follow-up after potentially curative resection.

Mokhles S, Macbeth F, Farewell V, Fiorentino F, Williams NR, Younes RN, Takkenberg JJ, Treasure T.

Br J Surg. 2016 Sep;103(10):1259-68. doi: 10.1002/bjs.10233. Epub 2016 Aug 4. Review.

38.

Reduced Mortality With Partial-Breast Irradiation for Early Breast Cancer: A Meta-Analysis of Randomized Trials.

Vaidya JS, Bulsara M, Wenz F, Coombs N, Singer J, Ebbs S, Massarut S, Saunders C, Douek M, Williams NR, Joseph D, Tobias JS, Baum M.

Int J Radiat Oncol Biol Phys. 2016 Oct 1;96(2):259-265. doi: 10.1016/j.ijrobp.2016.05.008. Epub 2016 May 13. Review.

39.

Multiscale Mechano-Biological Finite Element Modelling of Oncoplastic Breast Surgery-Numerical Study towards Surgical Planning and Cosmetic Outcome Prediction.

Vavourakis V, Eiben B, Hipwell JH, Williams NR, Keshtgar M, Hawkes DJ.

PLoS One. 2016 Jul 28;11(7):e0159766. doi: 10.1371/journal.pone.0159766. eCollection 2016.

40.

Five-Year Follow-Up of Bilateral Epidural Prefrontal Cortical Stimulation for Treatment-Resistant Depression.

Williams NR, Short EB, Hopkins T, Bentzley BS, Sahlem GL, Pannu J, Schmidt M, Borckardt JJ, Korte JE, George MS, Takacs I, Nahas Z.

Brain Stimul. 2016 Nov - Dec;9(6):897-904. doi: 10.1016/j.brs.2016.06.054. Epub 2016 Jun 28.

PMID:
27443912
41.

Unilateral ultra-brief pulse electroconvulsive therapy for depression in Parkinson's disease.

Williams NR, Bentzley BS, Sahlem GL, Pannu J, Korte JE, Revuelta G, Short EB, George MS.

Acta Neurol Scand. 2017 Apr;135(4):407-411. doi: 10.1111/ane.12614. Epub 2016 May 31.

42.

The use of onestep nucleic acid amplification (OSNA) and tumour related factors in the treatment of axillary breast cancer: A predictive model.

Banerjee SM, Williams NR, Davidson TI, El Sheikh S, Tran-Dang M, Davison S, Ghosh D, Keshtgar MR.

Eur J Surg Oncol. 2016 May;42(5):641-9. doi: 10.1016/j.ejso.2016.02.245. Epub 2016 Mar 2.

PMID:
26979647
43.

Quantification of 18FDG in the Normal Colon-A First Step in Investigating Whether Its Presence Is a Marker of a Physiological Process.

Bardhan KD, Cullis J, Williams NR, Arasaradnam RP, Wilson AJ.

PLoS One. 2016 Jan 28;11(1):e0147838. doi: 10.1371/journal.pone.0147838. eCollection 2016.

44.

Low-cost surface reconstruction for aesthetic results assessment and prediction in breast cancer surgery.

Lacher RM, Hipwell JH, Williams NR, Keshtgar MR, Hawkes DJ, Stoyanov D.

Conf Proc IEEE Eng Med Biol Soc. 2015 Aug;2015:5871-4. doi: 10.1109/EMBC.2015.7319727.

PMID:
26737627
45.

NMDA antagonist treatment of depression.

Williams NR, Schatzberg AF.

Curr Opin Neurobiol. 2016 Feb;36:112-7. doi: 10.1016/j.conb.2015.11.001. Epub 2015 Dec 11. Review.

PMID:
26687375
46.

Reward circuit DBS improves Parkinson's gait along with severe depression and OCD.

Williams NR, Hopkins TR, Short EB, Sahlem GL, Snipes J, Revuelta GJ, George MS, Takacs I.

Neurocase. 2016;22(2):201-4. doi: 10.1080/13554794.2015.1112019. Epub 2015 Dec 7.

47.

Symmetric Biomechanically Guided Prone-to-Supine Breast Image Registration.

Eiben B, Vavourakis V, Hipwell JH, Kabus S, Buelow T, Lorenz C, Mertzanidou T, Reis S, Williams NR, Keshtgar M, Hawkes DJ.

Ann Biomed Eng. 2016 Jan;44(1):154-73. doi: 10.1007/s10439-015-1496-z. Epub 2015 Nov 17.

48.

Oscillating Square Wave Transcranial Direct Current Stimulation (tDCS) Delivered During Slow Wave Sleep Does Not Improve Declarative Memory More Than Sham: A Randomized Sham Controlled Crossover Study.

Sahlem GL, Badran BW, Halford JJ, Williams NR, Korte JE, Leslie K, Strachan M, Breedlove JL, Runion J, Bachman DL, Uhde TW, Borckardt JJ, George MS.

Brain Stimul. 2015 May-Jun;8(3):528-34. doi: 10.1016/j.brs.2015.01.414. Epub 2015 Feb 16.

49.

Role of functional imaging in the development and refinement of invasive neuromodulation for psychiatric disorders.

Williams NR, Taylor JJ, Lamb K, Hanlon CA, Short EB, George MS.

World J Radiol. 2014 Oct 28;6(10):756-78. doi: 10.4329/wjr.v6.i10.756. Review.

50.

Beyond neural cubism: promoting a multidimensional view of brain disorders by enhancing the integration of neurology and psychiatry in education.

Taylor JJ, Williams NR, George MS.

Acad Med. 2015 May;90(5):581-6. doi: 10.1097/ACM.0000000000000530. Review.

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