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Investigating the neural basis of cognitive control dysfunction in mood disorders.

Breukelaar IA, Erlinger M, Harris A, Boyce P, Hazell P, Grieve SM, Antees C, Foster S, Gomes L, Williams LM, Malhi GS, Korgaonkar MS.

Bipolar Disord. 2019 Oct 11. doi: 10.1111/bdi.12844. [Epub ahead of print]


Connectivity of the Cognitive Control Network During Response Inhibition as a Predictive and Response Biomarker in Major Depression: Evidence From a Randomized Clinical Trial.

Tozzi L, Goldstein-Piekarski AN, Korgaonkar MS, Williams LM.

Biol Psychiatry. 2019 Aug 21. pii: S0006-3223(19)31617-8. doi: 10.1016/j.biopsych.2019.08.005. [Epub ahead of print]


Potential relationship between dietary long-chain saturated fatty acids and hypothalamic dysfunction in obesity.

Sergi D, Williams LM.

Nutr Rev. 2019 Sep 18. pii: nuz056. doi: 10.1093/nutrit/nuz056. [Epub ahead of print]


Deep phenotyping of attention impairments and the 'Inattention Biotype' in Major Depressive Disorder.

Keller AS, Ball TM, Williams LM.

Psychol Med. 2019 Sep 3:1-10. doi: 10.1017/S0033291719002290. [Epub ahead of print]


Early and reversible changes to the hippocampal proteome in mice on a high-fat diet.

McLean FH, Campbell FM, Sergi D, Grant C, Morris AC, Hay EA, MacKenzie A, Mayer CD, Langston RF, Williams LM.

Nutr Metab (Lond). 2019 Aug 23;16:57. doi: 10.1186/s12986-019-0387-y. eCollection 2019.


Integrating sleep, neuroimaging, and computational approaches for precision psychiatry.

Goldstein-Piekarski AN, Holt-Gosselin B, O'Hora K, Williams LM.

Neuropsychopharmacology. 2019 Aug 19. doi: 10.1038/s41386-019-0483-8. [Epub ahead of print] Review.


Profound and reproducible patterns of reduced regional gray matter characterize major depressive disorder.

Hellewell SC, Welton T, Maller JJ, Lyon M, Korgaonkar MS, Koslow SH, Williams LM, Rush AJ, Gordon E, Grieve SM.

Transl Psychiatry. 2019 Jul 24;9(1):176. doi: 10.1038/s41398-019-0512-8.


A high-fat diet induces rapid changes in the mouse hypothalamic proteome.

McLean FH, Campbell FM, Langston RF, Sergi D, Resch C, Grant C, Morris AC, Mayer CD, Williams LM.

Nutr Metab (Lond). 2019 Apr 29;16:26. doi: 10.1186/s12986-019-0352-9. eCollection 2019.


Characterizing neurocognitive markers of familial risk for depression using multi-modal imaging, behavioral and self-report measures.

Watters AJ, Carpenter JS, Harris AWF, Korgaonkar MS, Williams LM.

J Affect Disord. 2019 Jun 15;253:336-342. doi: 10.1016/j.jad.2019.04.078. Epub 2019 Apr 17.


Dimensions of anxiety in Major depressive disorder and their use in predicting antidepressant treatment outcome: an iSPOT-D report.

Braund TA, Palmer DM, Williams LM, Harris AWF.

Psychol Med. 2019 Apr 26:1-11. doi: 10.1017/S0033291719000941. [Epub ahead of print]


Characterising anxiety in major depressive disorder and its use in predicting antidepressant treatment outcome: An iSPOT-D report.

Braund TA, Palmer DM, Williams LM, Harris AW.

Aust N Z J Psychiatry. 2019 Aug;53(8):782-793. doi: 10.1177/0004867419835933. Epub 2019 Mar 18.


Infraclavicular Nerve Block.

Williams LM, Cummings A.

StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2019 Jan-.
2019 Mar 23.


The effects of bullying in depression on white matter integrity.

Graziano RC, Bruce SE, Paul RH, Korgaonkar MS, Williams LM.

Behav Brain Res. 2019 May 2;363:149-154. doi: 10.1016/j.bbr.2019.01.054. Epub 2019 Jan 30.


Gender-specific structural abnormalities in major depressive disorder revealed by fixel-based analysis.

Lyon M, Welton T, Varda A, Maller JJ, Broadhouse K, Korgaonkar MS, Koslow SH, Williams LM, Gordon E, Rush AJ, Grieve SM.

Neuroimage Clin. 2019;21:101668. doi: 10.1016/j.nicl.2019.101668. Epub 2019 Jan 8.


Diazepam is not a direct allosteric modulator of α1-adrenoceptors, but modulates receptor signaling by inhibiting phosphodiesterase-4.

Williams LM, He X, Vaid TM, Abdul-Ridha A, Whitehead AR, Gooley PR, Bathgate RAD, Williams SJ, Scott DJ.

Pharmacol Res Perspect. 2018 Dec 26;7(1):e00455. doi: 10.1002/prp2.455. eCollection 2019 Feb.


A locus on chromosome 5 shows African ancestry-limited association with alloimmunization in sickle cell disease.

Williams LM, Qi Z, Batai K, Hooker S, Hall NJ, Machado RF, Chen A, Campbell-Lee S, Guan Y, Kittles R, Hanchard NA.

Blood Adv. 2018 Dec 26;2(24):3637-3647. doi: 10.1182/bloodadvances.2018020594.



Williams LM, Fitzgerald BM.

StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2019 Jan-.
2019 Oct 3.


SerpinA3N is a novel hypothalamic gene upregulated by a high-fat diet and leptin in mice.

Sergi D, Campbell FM, Grant C, Morris AC, Bachmair EM, Koch C, McLean FH, Muller A, Hoggard N, de Roos B, Porteiro B, Boekschoten MV, McGillicuddy FC, Kahn D, Nicol P, Benzler J, Mayer CD, Drew JE, Roche HM, Muller M, Nogueiras R, Dieguez C, Tups A, Williams LM.

Genes Nutr. 2018 Nov 29;13:28. doi: 10.1186/s12263-018-0619-1. eCollection 2018.


Striatal dopamine deficits predict reductions in striatal functional connectivity in major depression: a concurrent 11C-raclopride positron emission tomography and functional magnetic resonance imaging investigation.

Hamilton JP, Sacchet MD, Hjørnevik T, Chin FT, Shen B, Kämpe R, Park JH, Knutson BD, Williams LM, Borg N, Zaharchuk G, Camacho MC, Mackey S, Heilig M, Drevets WC, Glover GH, Gambhir SS, Gotlib IH.

Transl Psychiatry. 2018 Nov 30;8(1):264. doi: 10.1038/s41398-018-0316-2.


Identification of Subclinical Language Deficit Using Machine Learning Classification Based on Poststroke Functional Connectivity Derived from Low Frequency Oscillations.

Mohanty R, Nair VA, Tellapragada N, Williams LM Jr, Kang TJ, Prabhakaran V.

Brain Connect. 2019 Mar;9(2):194-208. doi: 10.1089/brain.2018.0597. Epub 2019 Feb 7.


A negative association between brainstem pontine grey-matter volume, well-being and resilience in healthy twins

Gatt JM, Burton KLO, Routledge KM, Grasby KL, Korgaonkar MS, Grieve SM, Schofield PR, Harris AWF, Clark CR, Williams LM.

J Psychiatry Neurosci. 2018 Nov 1;43(6):386-395.


Dietary fibers inhibit obesity in mice, but host responses in the cecum and liver appear unrelated to fiber-specific changes in cecal bacterial taxonomic composition.

Drew JE, Reichardt N, Williams LM, Mayer CD, Walker AW, Farquharson AJ, Kastora S, Farquharson F, Milligan G, Morrison DJ, Preston T, Flint HJ, Louis P.

Sci Rep. 2018 Oct 22;8(1):15566. doi: 10.1038/s41598-018-34081-8.


Amygdala Activation and Connectivity to Emotional Processing Distinguishes Asymptomatic Patients With Bipolar Disorders and Unipolar Depression.

Korgaonkar MS, Erlinger M, Breukelaar IA, Boyce P, Hazell P, Antees C, Foster S, Grieve SM, Gomes L, Williams LM, Harris AWF, Malhi GS.

Biol Psychiatry Cogn Neurosci Neuroimaging. 2019 Apr;4(4):361-370. doi: 10.1016/j.bpsc.2018.08.012. Epub 2018 Aug 31.


Developmental Regulation of Nuclear Factor Erythroid-2 Related Factors (nrfs) by AHR1b in Zebrafish (Danio rerio).

Ulin A, Henderson J, Pham MT, Meyo J, Chen Y, Karchner SI, Goldstone JV, Hahn ME, Williams LM.

Toxicol Sci. 2019 Feb 1;167(2):536-545. doi: 10.1093/toxsci/kfy257.


Heart rate variability as a biomarker of anxious depression response to antidepressant medication.

Kircanski K, Williams LM, Gotlib IH.

Depress Anxiety. 2019 Jan;36(1):63-71. doi: 10.1002/da.22843. Epub 2018 Oct 12.


Ventilator Safety.

Williams LM, Sharma S.

StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2019 Jan-.
2019 May 13.


Multi-unit relations among neural, self-report, and behavioral correlates of emotion regulation in comorbid depression and obesity.

Pines AR, Sacchet MD, Kullar M, Ma J, Williams LM.

Sci Rep. 2018 Sep 19;8(1):14032. doi: 10.1038/s41598-018-32394-2.


Cognitive ability is associated with changes in the functional organization of the cognitive control brain network.

A Breukelaar I, Williams LM, Antees C, Grieve SM, Foster SL, Gomes L, Korgaonkar MS.

Hum Brain Mapp. 2018 Dec;39(12):5028-5038. doi: 10.1002/hbm.24342. Epub 2018 Aug 23.


Rapid and reversible impairment of episodic memory by a high-fat diet in mice.

McLean FH, Grant C, Morris AC, Horgan GW, Polanski AJ, Allan K, Campbell FM, Langston RF, Williams LM.

Sci Rep. 2018 Aug 10;8(1):11976. doi: 10.1038/s41598-018-30265-4.


Palmitic acid triggers inflammatory responses in N42 cultured hypothalamic cells partially via ceramide synthesis but not via TLR4.

Sergi D, Morris AC, Kahn DE, McLean FH, Hay EA, Kubitz P, MacKenzie A, Martinoli MG, Drew JE, Williams LM.

Nutr Neurosci. 2018 Jul 21:1-14. doi: 10.1080/1028415X.2018.1501533. [Epub ahead of print]


Effect of Repetitive Transcranial Magnetic Stimulation on Treatment-Resistant Major Depression in US Veterans: A Randomized Clinical Trial.

Yesavage JA, Fairchild JK, Mi Z, Biswas K, Davis-Karim A, Phibbs CS, Forman SD, Thase M, Williams LM, Etkin A, O'Hara R, Georgette G, Beale T, Huang GD, Noda A, George MS; VA Cooperative Studies Program Study Team.

JAMA Psychiatry. 2018 Sep 1;75(9):884-893. doi: 10.1001/jamapsychiatry.2018.1483.


A negative association between brainstem pontine grey-matter volume, well-being and resilience in healthy twins.

Gatt JM, Burton KLO, Routledge KM, Grasby KL, Korgaonkar MS, Grieve SM, Schofield PR, Harris AWF, Clark CR, Williams LM.

J Psychiatry Neurosci. 2018 Jun 20;43(5):170125. doi: 10.1503/jpn.170125. [Epub ahead of print]


Attribution bias underlying burns-induced anxiety symptoms.

Farag M, Watson EJR, Nenadlová K, Asher C, Al-Aidarous S, Mandalia S, Williams LM, Edginton TL, Collins D, Vizcaychipi MP.

Burns. 2018 Sep;44(6):1502-1508. doi: 10.1016/j.burns.2018.05.004. Epub 2018 Jun 7.


"Motoring in idle": The default mode and somatomotor networks are overactive in children and adolescents with functional neurological symptoms.

Kozlowska K, Spooner CJ, Palmer DM, Harris A, Korgaonkar MS, Scher S, Williams LM.

Neuroimage Clin. 2018 Feb 17;18:730-743. doi: 10.1016/j.nicl.2018.02.003. eCollection 2018.


More Research Needed on the Association Between Genotype and Antidepressant Response: Response to Fabbri et al.

Williams LM.

Am J Psychiatry. 2018 Jun 1;175(6):576-577. doi: 10.1176/appi.ajp.2018.18010070r. No abstract available.


Electrocortical reactivity to negative and positive facial expressions in individuals with a family history of major depression.

Watters AJ, Harris AWF, Williams LM.

Biol Psychol. 2018 Jul;136:127-135. doi: 10.1016/j.biopsycho.2018.05.015. Epub 2018 May 21.


Perioperative Research into Memory (PRiMe): Cognitive impairment following a severe burn injury and critical care admission, part 1.

Watson EJR, Nenadlová K, Clancy OH, Farag M, Nordin NA, Nilsen A, Mehmet ART, Al-Hindawi A, Mandalia S, Williams LM, Edginton TL, Vizcaychipi MP.

Burns. 2018 Aug;44(5):1167-1178. doi: 10.1016/j.burns.2018.04.011. Epub 2018 May 8.


Genetic correlations between wellbeing, depression and anxiety symptoms and behavioral responses to the emotional faces task in healthy twins.

Routledge KM, Williams LM, Harris AWF, Schofield PR, Clark CR, Gatt JM.

Psychiatry Res. 2018 Jun;264:385-393. doi: 10.1016/j.psychres.2018.03.042. Epub 2018 Mar 19.


Response inhibition and emotional cognition improved by atomoxetine in children and adolescents with ADHD: The ACTION randomized controlled trial.

Griffiths KR, Leikauf JE, Tsang TW, Clarke S, Hermens DF, Efron D, Williams LM, Kohn MR.

J Psychiatr Res. 2018 Jul;102:57-64. doi: 10.1016/j.jpsychires.2018.03.009. Epub 2018 Mar 27.


Bruton's tyrosine kinase regulates TLR7/8-induced TNF transcription via nuclear factor-κB recruitment.

Page TH, Urbaniak AM, Espirito Santo AI, Danks L, Smallie T, Williams LM, Horwood NJ.

Biochem Biophys Res Commun. 2018 May 5;499(2):260-266. doi: 10.1016/j.bbrc.2018.03.140. Epub 2018 Mar 22.


Determinants of Ligand Subtype-Selectivity at α1A-Adrenoceptor Revealed Using Saturation Transfer Difference (STD) NMR.

Yong KJ, Vaid TM, Shilling PJ, Wu FJ, Williams LM, Deluigi M, Plückthun A, Bathgate RAD, Gooley PR, Scott DJ.

ACS Chem Biol. 2018 Apr 20;13(4):1090-1102. doi: 10.1021/acschembio.8b00191. Epub 2018 Mar 22.


Intrinsic functional connectivity predicts remission on antidepressants: a randomized controlled trial to identify clinically applicable imaging biomarkers.

Goldstein-Piekarski AN, Staveland BR, Ball TM, Yesavage J, Korgaonkar MS, Williams LM.

Transl Psychiatry. 2018 Mar 6;8(1):57. doi: 10.1038/s41398-018-0100-3.


Intrinsic, task-evoked and absolute gamma synchrony during cognitive processing in first onset schizophrenia.

Brennan AM, Williams LM, Harris AWF.

J Psychiatr Res. 2018 Apr;99:10-21. doi: 10.1016/j.jpsychires.2017.12.004. Epub 2017 Dec 8.


Resting-State Functional MRI: Everything That Nonexperts Have Always Wanted to Know.

Lv H, Wang Z, Tong E, Williams LM, Zaharchuk G, Zeineh M, Goldstein-Piekarski AN, Ball TM, Liao C, Wintermark M.

AJNR Am J Neuroradiol. 2018 Aug;39(8):1390-1399. doi: 10.3174/ajnr.A5527. Epub 2018 Jan 18. Review.


Embryonic exposure to Mono(2-ethylhexyl) phthalate (MEHP) disrupts pancreatic organogenesis in zebrafish (Danio rerio).

Jacobs HM, Sant KE, Basnet A, Williams LM, Moss JB, Timme-Laragy AR.

Chemosphere. 2018 Mar;195:498-507. doi: 10.1016/j.chemosphere.2017.12.094. Epub 2017 Dec 15.


A Public Database of Immersive VR Videos with Corresponding Ratings of Arousal, Valence, and Correlations between Head Movements and Self Report Measures.

Li BJ, Bailenson JN, Pines A, Greenleaf WJ, Williams LM.

Front Psychol. 2017 Dec 5;8:2116. doi: 10.3389/fpsyg.2017.02116. eCollection 2017.


What can treatment research offer general practice?

Humphreys K, Williams LM.

Lancet Psychiatry. 2018 Apr;5(4):295-297. doi: 10.1016/S2215-0366(17)30512-6. Epub 2017 Dec 14. No abstract available.


Sex, Sleep Deprivation, and the Anxious Brain.

Goldstein-Piekarski AN, Greer SM, Saletin JM, Harvey AG, Williams LM, Walker MP.

J Cogn Neurosci. 2018 Apr;30(4):565-578. doi: 10.1162/jocn_a_01225. Epub 2017 Dec 15.


Antidepressant Outcomes Predicted by Genetic Variation in Corticotropin-Releasing Hormone Binding Protein.

O'Connell CP, Goldstein-Piekarski AN, Nemeroff CB, Schatzberg AF, Debattista C, Carrillo-Roa T, Binder EB, Dunlop BW, Craighead WE, Mayberg HS, Williams LM.

Am J Psychiatry. 2018 Mar 1;175(3):251-261. doi: 10.1176/appi.ajp.2017.17020172. Epub 2017 Dec 15.


Transdiagnostic Symptom Clusters and Associations With Brain, Behavior, and Daily Function in Mood, Anxiety, and Trauma Disorders.

Grisanzio KA, Goldstein-Piekarski AN, Wang MY, Rashed Ahmed AP, Samara Z, Williams LM.

JAMA Psychiatry. 2018 Feb 1;75(2):201-209. doi: 10.1001/jamapsychiatry.2017.3951. Erratum in: JAMA Psychiatry. 2018 Feb 1;75(2):215. JAMA Psychiatry. 2018 Dec 1;75(12):1304.

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