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Myocardial B cells are a subset of circulating lymphocytes with delayed transit through the heart.

Adamo L, Rocha-Resende C, Lin CY, Evans S, Williams JW, Dun H, Li W, Mpoy C, Andhey P, Rogers BE, Lavine K, Kreisel D, Artyomov MN, Randolph GJ, Mann D.

JCI Insight. 2020 Jan 16. pii: 134700. doi: 10.1172/jci.insight.134700. [Epub ahead of print]


Effectiveness of Acute Care Remote Triage Systems: a Systematic Review.

Boggan JC, Shoup JP, Whited JD, Van Voorhees E, Gordon AM, Rushton S, Lewinski AA, Tabriz AA, Adam S, Fulton J, Kosinski AS, Van Noord MG, Williams JW Jr, Goldstein KM, Gierisch JM.

J Gen Intern Med. 2020 Jan 2. doi: 10.1007/s11606-019-05585-4. [Epub ahead of print] Review.


Neutrophils promote VLA-4-dependent B cell antigen presentation and accumulation within the meninges during neuroinflammation.

Parker Harp CR, Archambault AS, Cheung M, Williams JW, Czepielewski RS, Duncker PC, Kilgore AJ, Miller AT, Segal BM, Kim AHJ, Randolph GJ, Wu GF.

Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24221-24230. doi: 10.1073/pnas.1909098116. Epub 2019 Nov 7.


Differing climatic mechanisms control transient and accumulated vegetation novelty in Europe and eastern North America.

Burke KD, Williams JW, Brewer S, Finsinger W, Giesecke T, Lorenz DJ, Ordonez A.

Philos Trans R Soc Lond B Biol Sci. 2019 Dec 23;374(1788):20190218. doi: 10.1098/rstb.2019.0218. Epub 2019 Nov 4.


Machine-learning based reconstructions of primary and secondary climate variables from North American and European fossil pollen data.

Salonen JS, Korpela M, Williams JW, Luoto M.

Sci Rep. 2019 Nov 1;9(1):15805. doi: 10.1038/s41598-019-52293-4.


Qualitative Exploration of Engaging Patients as Advisors in a Program of Evidence Synthesis: Cobuilding the Science to Enhance Impact.

Gierisch JM, Hughes JM, Williams JW Jr, Gordon AM, Goldstein KM.

Med Care. 2019 Oct;57 Suppl 10 Suppl 3:S246-S252. doi: 10.1097/MLR.0000000000001174.


Quantifying trends and uncertainty in prehistoric forest composition in the upper Midwestern United States.

Dawson A, Paciorek CJ, Goring SJ, Jackson ST, McLachlan JS, Williams JW.

Ecology. 2019 Dec;100(12):e02856. doi: 10.1002/ecy.2856. Epub 2019 Sep 13.


B Cell-Mediated Antigen Presentation through MHC Class II Is Dispensable for Atherosclerosis Progression.

Williams JW, Elvington A, Kessler S, Wohltmann M, Wu GF, Randolph GJ.

Immunohorizons. 2019 Jan 21;3(1):37-44. doi: 10.4049/immunohorizons.1800015.


Self-management of Epilepsy: A Systematic Review.

Luedke MW, Blalock DV, Goldstein KM, Kosinski AS, Sinha SR, Drake C, Lewis JD, Husain AM, Lewinski AA, Shapiro A, Gierisch JM, Tran TT, Gordon AM, Van Noord MG, Bosworth HB, Williams JW.

Ann Intern Med. 2019 Jul 16;171(2):117-126. doi: 10.7326/M19-0458. Epub 2019 Jul 2.


A Stromal Niche Defined by Expression of the Transcription Factor WT1 Mediates Programming and Homeostasis of Cavity-Resident Macrophages.

Buechler MB, Kim KW, Onufer EJ, Williams JW, Little CC, Dominguez CX, Li Q, Sandoval W, Cooper JE, Harris CA, Junttila MR, Randolph GJ, Turley SJ.

Immunity. 2019 Jul 16;51(1):119-130.e5. doi: 10.1016/j.immuni.2019.05.010. Epub 2019 Jun 20.


Land-use and climatic causes of environmental novelty in Wisconsin since 1890.

Williams JW, Burke KD, Crossley MS, Grant DA, Radeloff VC.

Ecol Appl. 2019 Oct;29(7):e01955. doi: 10.1002/eap.1955. Epub 2019 Jul 16.


Anticonvulsants for behavioral and psychological symptoms in dementia: protocol for a systematic review.

Benjamin S, Williams JW Jr, Cotton C, Tung J, An H, Sanger S, Ho JM.

Syst Rev. 2019 May 18;8(1):118. doi: 10.1186/s13643-019-1025-5.


Cytokine Circuits in Cardiovascular Disease.

Williams JW, Huang LH, Randolph GJ.

Immunity. 2019 Apr 16;50(4):941-954. doi: 10.1016/j.immuni.2019.03.007. Review.


Emergency Department Interventions for Older Adults: A Systematic Review.

Hughes JM, Freiermuth CE, Shepherd-Banigan M, Ragsdale L, Eucker SA, Goldstein K, Hastings SN, Rodriguez RL, Fulton J, Ramos K, Tabriz AA, Gordon AM, Gierisch JM, Kosinski A, Williams JW Jr.

J Am Geriatr Soc. 2019 Jul;67(7):1516-1525. doi: 10.1111/jgs.15854. Epub 2019 Mar 15. Review.


The potential role of intrinsic processes in generating abrupt and quasi-synchronous tree declines during the Holocene.

Ramiadantsoa T, Stegner MA, Williams JW, Ives AR.

Ecology. 2019 Feb;100(2):e02579. doi: 10.1002/ecy.2579.


Pliocene and Eocene provide best analogs for near-future climates.

Burke KD, Williams JW, Chandler MA, Haywood AM, Lunt DJ, Otto-Bliesner BL.

Proc Natl Acad Sci U S A. 2018 Dec 26;115(52):13288-13293. doi: 10.1073/pnas.1809600115. Epub 2018 Dec 10.


Integrated outpatient palliative care for patients with advanced cancer: A systematic review and meta-analysis.

Fulton JJ, LeBlanc TW, Cutson TM, Porter Starr KN, Kamal A, Ramos K, Freiermuth CE, McDuffie JR, Kosinski A, Adam S, Nagi A, Williams JW.

Palliat Med. 2019 Feb;33(2):123-134. doi: 10.1177/0269216318812633. Epub 2018 Nov 29. No abstract available.


Non-apoptotic Fas (CD95) Signaling on T Cells Regulates the Resolution of Th2-Mediated Inflammation.

Williams JW, Ferreira CM, Blaine KM, Rayon C, Velázquez F, Tong J, Peter ME, Sperling AI.

Front Immunol. 2018 Nov 1;9:2521. doi: 10.3389/fimmu.2018.02521. eCollection 2018.


Allergen Exposure in Lymphopenic Fas-Deficient Mice Results in Persistent Eosinophilia Due to Defects in Resolution of Inflammation.

Ferreira CM, Williams JW, Tong J, Rayon C, Blaine KM, Sperling AI.

Front Immunol. 2018 Oct 30;9:2395. doi: 10.3389/fimmu.2018.02395. eCollection 2018.


Mechanistic modeling of environmental drivers of woolly mammoth carrying capacity declines on St. Paul Island.

Wang Y, Porter W, Mathewson PD, Miller PA, Graham RW, Williams JW.

Ecology. 2018 Dec;99(12):2721-2730. doi: 10.1002/ecy.2524. Epub 2018 Oct 26.


A double-blind placebo controlled trial into the impacts of HMB supplementation and exercise on free-living muscle protein synthesis, muscle mass and function, in older adults.

Din USU, Brook MS, Selby A, Quinlan J, Boereboom C, Abdullah H, Franchi M, Narici MV, Phillips BE, Williams JW, Rathmacher JA, Wilkinson DJ, Atherton PJ, Smith K.

Clin Nutr. 2019 Oct;38(5):2071-2078. doi: 10.1016/j.clnu.2018.09.025. Epub 2018 Sep 27.


Macrophage Biology, Classification, and Phenotype in Cardiovascular Disease: JACC Macrophage in CVD Series (Part 1).

Williams JW, Giannarelli C, Rahman A, Randolph GJ, Kovacic JC.

J Am Coll Cardiol. 2018 Oct 30;72(18):2166-2180. doi: 10.1016/j.jacc.2018.08.2148. Review.


Transcriptome Analysis Reveals Nonfoamy Rather Than Foamy Plaque Macrophages Are Proinflammatory in Atherosclerotic Murine Models.

Kim K, Shim D, Lee JS, Zaitsev K, Williams JW, Kim KW, Jang MY, Seok Jang H, Yun TJ, Lee SH, Yoon WK, Prat A, Seidah NG, Choi J, Lee SP, Yoon SH, Nam JW, Seong JK, Oh GT, Randolph GJ, Artyomov MN, Cheong C, Choi JH.

Circ Res. 2018 Oct 26;123(10):1127-1142. doi: 10.1161/CIRCRESAHA.118.312804.


Sertoli-Leydig Cell Tumour and DICER1 Mutation: A Case Report and Review of the Literature.

Wormald B, Elorbany S, Hanson H, Williams JW, Heenan S, Barton DPJ.

Case Rep Obstet Gynecol. 2018 Sep 25;2018:7927362. doi: 10.1155/2018/7927362. eCollection 2018.


Telehealth Interventions Designed for Women: an Evidence Map.

Goldstein KM, Zullig LL, Dedert EA, Alishahi Tabriz A, Brearly TW, Raitz G, Sata SS, Whited JD, Bosworth HB, Gordon AM, Nagi A, Williams JW Jr, Gierisch JM.

J Gen Intern Med. 2018 Dec;33(12):2191-2200. doi: 10.1007/s11606-018-4655-8. Epub 2018 Oct 3. Review.


A new terrestrial palaeoenvironmental record from the Bering Land Bridge and context for human dispersal.

Wooller MJ, Saulnier-Talbot É, Potter BA, Belmecheri S, Bigelow N, Choy K, Cwynar LC, Davies K, Graham RW, Kurek J, Langdon P, Medeiros A, Rawcliffe R, Wang Y, Williams JW.

R Soc Open Sci. 2018 Jun 20;5(6):180145. doi: 10.1098/rsos.180145. eCollection 2018 Jun.


Interventions to Support Caregivers or Families of Patients with TBI, PTSD, or Polytrauma: A Systematic Review [Internet].

Shepherd-Banigan ME, McDuffie JR, Shapiro A, Brancu M, Sperber N, Mehta NN, van Houtven CH, Williams JW Jr.

Washington (DC): Department of Veterans Affairs (US); 2018 Feb.


Broad-Spectrum and Personalized Guide RNAs for CRISPR/Cas9 HIV-1 Therapeutics.

Dampier W, Sullivan NT, Mell JC, Pirrone V, Ehrlich GD, Chung CH, Allen AG, DeSimone M, Zhong W, Kercher K, Passic S, Williams JW, Szep Z, Khalili K, Jacobson JM, Nonnemacher MR, Wigdahl B.

AIDS Res Hum Retroviruses. 2018 Nov;34(11):950-960. doi: 10.1089/AID.2017.0274. Epub 2018 Aug 27.


Assessing agreement among alternative climate change projections to inform conservation recommendations in the contiguous United States.

Belote RT, Carroll C, Martinuzzi S, Michalak J, Williams JW, Williamson MA, Aplet GH.

Sci Rep. 2018 Jun 21;8(1):9441. doi: 10.1038/s41598-018-27721-6.


Behavioral health integration model.

Basu S, Williams JW Jr, Phillips RS.

J Gen Intern Med. 2018 Oct;33(10):1597. doi: 10.1007/s11606-018-4512-9. No abstract available.


Limited Macrophage Positional Dynamics in Progressing or Regressing Murine Atherosclerotic Plaques-Brief Report.

Williams JW, Martel C, Potteaux S, Esaulova E, Ingersoll MA, Elvington A, Saunders BT, Huang LH, Habenicht AJ, Zinselmeyer BH, Randolph GJ.

Arterioscler Thromb Vasc Biol. 2018 Aug;38(8):1702-1710. doi: 10.1161/ATVBAHA.118.311319.


GRADE guidelines: 20. Assessing the certainty of evidence in the importance of outcomes or values and preferences-inconsistency, imprecision, and other domains.

Zhang Y, Coello PA, Guyatt GH, Yepes-Nuñez JJ, Akl EA, Hazlewood G, Pardo-Hernandez H, Etxeandia-Ikobaltzeta I, Qaseem A, Williams JW Jr, Tugwell P, Flottorp S, Chang Y, Zhang Y, Mustafa RA, Rojas MX, Xie F, Schünemann HJ.

J Clin Epidemiol. 2019 Jul;111:83-93. doi: 10.1016/j.jclinepi.2018.05.011. Epub 2018 May 22.


Abrupt Change in Ecological Systems: Inference and Diagnosis.

Ratajczak Z, Carpenter SR, Ives AR, Kucharik CJ, Ramiadantsoa T, Stegner MA, Williams JW, Zhang J, Turner MG.

Trends Ecol Evol. 2018 Jul;33(7):513-526. doi: 10.1016/j.tree.2018.04.013. Epub 2018 May 18. Review.


Below-ground biotic interactions moderated the postglacial range dynamics of trees.

Pither J, Pickles BJ, Simard SW, Ordonez A, Williams JW.

New Phytol. 2018 Dec;220(4):1148-1160. doi: 10.1111/nph.15203. Epub 2018 May 17.


Interventions That Support or Involve Caregivers or Families of Patients with Traumatic Injury: a Systematic Review.

Shepherd-Banigan ME, Shapiro A, McDuffie JR, Brancu M, Sperber NR, Van Houtven CH, Kosinski AS, Mehta NN, Nagi A, Williams JW Jr.

J Gen Intern Med. 2018 Jul;33(7):1177-1186. doi: 10.1007/s11606-018-4417-7. Epub 2018 May 7. Review.


Trial protocol: a clustered, randomised, longitudinal, type 2 translational trial of alcohol consumption and alcohol-related harm among adolescents in Australia.

Rowland B, Abraham C, Carter R, Abimanyi-Ochom J, Kelly AB, Kremer P, Williams JW, Smith R, Hall JK, Wagner D, Renner H, Hosseini T, Osborn A, Mohebbi M, Toumbourou JW.

BMC Public Health. 2018 Apr 27;18(1):559. doi: 10.1186/s12889-018-5452-3.


Diagnostic Accuracy of Screening and Treatment of Post–Acute Coronary Syndrome Depression: A Systematic Review [Internet].

Williams JW Jr, Nieuwsma JA, Namdari N, Washam JB, Raitz G, Blumenthal JA, Jiang W, Yapa R, McBroom AJ, Lallinger K, Schmidt R, Kosinski AS, Sanders GD.

Rockville (MD): Agency for Healthcare Research and Quality (US); 2017 Nov.


Does information from increase transparency and reduce bias? Results from a five-report case series.

Adam GP, Springs S, Trikalinos T, Williams JW Jr, Eaton JL, Von Isenburg M, Gierisch JM, Wilson LM, Robinson KA, Viswanathan M, Middleton JC, Forman-Hoffman VL, Berliner E, Kaplan RM.

Syst Rev. 2018 Apr 16;7(1):59. doi: 10.1186/s13643-018-0726-5.


An Examination of Gender Differences in the Association of Adolescent Substance use with Eating and Weight Loss Attitudes.

Thomas RL, Kelly AB, Chan GCK, Hides LM, Quinn CA, Kavanagh DJ, Williams JW.

Subst Use Misuse. 2018 Nov 10;53(13):2125-2131. doi: 10.1080/10826084.2018.1455703. Epub 2018 Apr 6.


Integrated Outpatient Palliative Care in Oncology [Internet].

Fulton J, LeBlanc T, Porter Star KN, Kamal A, Ramos K, Cutson T, Freiermuth C, McDuffie J, Adams S, Kosinkski A, von Isenburg M, Van Noord M, Williams JW Jr.

Washington (DC): Department of Veterans Affairs (US); 2017 Sep.


How will climate novelty influence ecological forecasts? Using the Quaternary to assess future reliability.

Fitzpatrick MC, Blois JL, Williams JW, Nieto-Lugilde D, Maguire KC, Lorenz DJ.

Glob Chang Biol. 2018 Aug;24(8):3575-3586. doi: 10.1111/gcb.14138. Epub 2018 Apr 17.


Challenges in profiling Australian scuba divers through surveys.

Lippmann J, Taylor DM, Stevenson C, Williams JW.

Diving Hyperb Med. 2018 Mar 31;48(1):23-30. doi: 10.28920/dhm48.1.23-30.


Contribution of metabolic disease to bone fragility in MAGP1-deficient mice.

Turecamo SE, Walji TA, Broekelmann TJ, Williams JW, Ivanov S, Wee NK, Procknow JD, McManus MR, Randolph GJ, Scheller EL, Mecham RP, Craft CS.

Matrix Biol. 2018 Apr;67:1-14. doi: 10.1016/j.matbio.2018.02.022. Epub 2018 Mar 5.


GRADE Guidelines: 19. Assessing the certainty of evidence in the importance of outcomes or values and preferences-Risk of bias and indirectness.

Zhang Y, Alonso-Coello P, Guyatt GH, Yepes-Nuñez JJ, Akl EA, Hazlewood G, Pardo-Hernandez H, Etxeandia-Ikobaltzeta I, Qaseem A, Williams JW Jr, Tugwell P, Flottorp S, Chang Y, Zhang Y, Mustafa RA, Rojas MX, Schünemann HJ.

J Clin Epidemiol. 2019 Jul;111:94-104. doi: 10.1016/j.jclinepi.2018.01.013. Epub 2018 Feb 13.


Student survey trends in reported alcohol use and influencing factors in Australia.

Toumbourou JW, Rowland B, Ghayour-Minaie M, Sherker S, Patton GC, Williams JW.

Drug Alcohol Rev. 2018 Apr;37 Suppl 1:S58-S66. doi: 10.1111/dar.12645. Epub 2018 Jan 12.


Management of Menopause Symptoms with Acupuncture: An Umbrella Systematic Review and Meta-Analysis.

Befus D, Coeytaux RR, Goldstein KM, McDuffie JR, Shepherd-Banigan M, Goode AP, Kosinski A, Van Noord MG, Adam SS, Masilamani V, Nagi A, Williams JW Jr.

J Altern Complement Med. 2018 Apr;24(4):314-323. doi: 10.1089/acm.2016.0408. Epub 2018 Jan 3. Review.


Supplemental Project To Assess the Transparency of Reporting for Trials Evaluating Treatment for Infertility [Internet].

Williams JW Jr, Eaton JL, Gierisch JM, Masilamani V, von Isenburg M, Chobot M.

Rockville (MD): Agency for Healthcare Research and Quality (US); 2017 Jun. No abstract available.

Free Books & Documents

Diagnostic Accuracy of Screening Tests and Treatment for Post-Acute Coronary Syndrome Depression: A Systematic Review.

Nieuwsma JA, Williams JW Jr, Namdari N, Washam JB, Raitz G, Blumenthal JA, Jiang W, Yapa R, McBroom AJ, Lallinger K, Schmidt R, Kosinski AS, Sanders GD.

Ann Intern Med. 2017 Nov 21;167(10):725-735. doi: 10.7326/M17-1811. Epub 2017 Nov 14. Review.


Metformin Use May Moderate the Effect of DPP-4 Inhibitors on Cardiovascular Outcomes.

Crowley MJ, Williams JW Jr, Kosinski AS, D'Alessio DA, Buse JB.

Diabetes Care. 2017 Dec;40(12):1787-1789. doi: 10.2337/dc17-1528. Epub 2017 Oct 19.


Econometrics as evidence? Examining the 'causal' connections between financial speculation and commodities prices.

Williams JW, Cook NM.

Soc Stud Sci. 2016 Oct;46(5):701-724. doi: 10.1177/0306312716658980. Epub 2016 Aug 20.


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