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Items: 1 to 50 of 587

1.

Sex-specific differences in endoplasmic reticulum aminopeptidase 1 modulation influence blood pressure and renin-angiotensin system responses.

Ranjit S, Wong JY, Tan JW, Sin Tay C, Lee JM, Yin Han Wong K, Pojoga LH, Brooks DL, Garza AE, Maris SA, Katayama IA, Williams JS, Rivera A, Adler GK, Williams GH, Romero JR.

JCI Insight. 2019 Nov 1;4(21). pii: 129615. doi: 10.1172/jci.insight.129615.

2.

Aldosterone: The Missing Cardiorenal Link.

Williams GH.

Am J Nephrol. 2019;50(5):329-332. doi: 10.1159/000503714. Epub 2019 Oct 29. No abstract available.

3.

Correction: Mapping the binding sites of antibodies utilized in programmed cell death ligand-1 predictive immunohistochemical assays for use with immuno-oncology therapies.

Lawson NL, Dix CI, Scorer PW, Stubbs CJ, Wong E, Hutchinson L, McCall EJ, Schimpl M, DeVries E, Walker J, Williams GH, Hunt J, Barker C.

Mod Pathol. 2019 Oct 22. doi: 10.1038/s41379-019-0379-5. [Epub ahead of print]

PMID:
31641230
4.

Mapping the binding sites of antibodies utilized in programmed cell death ligand-1 predictive immunohistochemical assays for use with immuno-oncology therapies.

Lawson NL, Dix CI, Scorer PW, Stubbs CJ, Wong E, Hutchinson L, McCall EJ, Schimpl M, DeVries E, Walker J, Williams GH, Hunt J, Barker C.

Mod Pathol. 2019 Sep 26. doi: 10.1038/s41379-019-0372-z. [Epub ahead of print] Erratum in: Mod Pathol. 2019 Oct 22;:.

PMID:
31558782
5.

Higher urinary cortisol levels associate with increased cardiovascular risk.

Haas AV, Hopkins PN, Brown NJ, Pojoga LH, Williams JS, Adler GK, Williams GH.

Endocr Connect. 2019 Jun 1;8(6):634-640. doi: 10.1530/EC-19-0182.

6.

Aldosterone Modulates the Mechanistic Target of Rapamycin Signaling in Male Mice.

Brooks DL, Garza AE, Katayama IA, Romero JR, Adler GK, Pojoga LH, Williams GH.

Endocrinology. 2019 Apr 1;160(4):716-728. doi: 10.1210/en.2018-00989.

PMID:
30726893
7.

Genetics of Human Primary Hypertension: Focus on Hormonal Mechanisms.

Manosroi W, Williams GH.

Endocr Rev. 2019 Jun 1;40(3):825-856. doi: 10.1210/er.2018-00071.

PMID:
30590482
8.

Histone demethylase LSD1 deficiency and biological sex: impact on blood pressure and aldosterone production.

Huang Y, Ting PY, Yao TM, Homma T, Brooks D, Katayama Rangel I, Adler GK, Romero JR, Williams JS, Pojoga LH, Williams GH.

J Endocrinol. 2019 Feb 1;240(2):111-122. doi: 10.1530/JOE-18-0247.

9.

Inner ear pathologies impair sodium-regulated ion transport in Meniere's disease.

Eckhard AH, Zhu M, O'Malley JT, Williams GH, Loffing J, Rauch SD, Nadol JB Jr, Liberman MC, Adams JC.

Acta Neuropathol. 2019 Feb;137(2):343-357. doi: 10.1007/s00401-018-1927-7. Epub 2018 Nov 2.

10.

Biological Sex Modulates the Adrenal and Blood Pressure Responses to Angiotensin II.

Shukri MZ, Tan JW, Manosroi W, Pojoga LH, Rivera A, Williams JS, Seely EW, Adler GK, Jaffe IZ, Karas RH, Williams GH, Romero JR.

Hypertension. 2018 Jun;71(6):1083-1090. doi: 10.1161/HYPERTENSIONAHA.117.11087. Epub 2018 Apr 23.

11.

Immunophenotypic analysis of cell cycle status in acute myeloid leukaemia: relationship to cytogenetics, genotype and clinical outcome.

Sellar RS, Gale RE, Khwaja A, Garbowski M, Loddo M, Stoeber K, Williams GH, Linch DC.

Br J Haematol. 2018 May;181(4):486-494. doi: 10.1111/bjh.15211. Epub 2018 Apr 20.

PMID:
29676467
12.

Caloric restriction improves glucose homeostasis, yet increases cardiometabolic risk in caveolin-1-deficient mice.

Mayurasakorn K, Hasanah N, Homma T, Homma M, Rangel IK, Garza AE, Romero JR, Adler GK, Williams GH, Pojoga LH.

Metabolism. 2018 Jun;83:92-101. doi: 10.1016/j.metabol.2018.01.012. Epub 2018 Feb 2.

PMID:
29410348
13.

Dysregulated aldosterone secretion in persons of African descent with endothelin-1 gene variants.

Tan JW, Gupta T, Manosroi W, Yao TM, Hopkins PN, Williams JS, Adler GK, Romero JR, Williams GH.

JCI Insight. 2017 Dec 7;2(23). pii: 95992. doi: 10.1172/jci.insight.95992.

14.

Combined Salt and Caloric Restrictions: Potential Adverse Outcomes.

Homma T, Homma M, Huang Y, Mayurasakorn K, Rodi NM, Hamid AAA, Hurwitz S, Yao T, Adler GK, Pojoga LH, Williams GH, Romero JR.

J Am Heart Assoc. 2017 Oct 11;6(10). pii: e005374. doi: 10.1161/JAHA.116.005374.

15.

Striatin Gene Polymorphic Variants Are Associated With Salt Sensitive Blood Pressure in Normotensives and Hypertensives.

Gupta T, Connors M, Tan JW, Manosroi W, Ahmed N, Ting PY, Garza AE, Romero JR, Hopkins PN, Williams JS, Williams GH.

Am J Hypertens. 2017 Dec 8;31(1):124-131. doi: 10.1093/ajh/hpx146.

16.

The Association of Estrogen Receptor-β Gene Variation With Salt-Sensitive Blood Pressure.

Manosroi W, Tan JW, Rariy CM, Sun B, Goodarzi MO, Saxena AR, Williams JS, Pojoga LH, Lasky-Su J, Cui J, Guo X, Taylor KD, Chen YI, Xiang AH, Hsueh WA, Raffel LJ, Buchanan TA, Rotter JI, Williams GH, Seely EW.

J Clin Endocrinol Metab. 2017 Nov 1;102(11):4124-4135. doi: 10.1210/jc.2017-00957.

17.

Making sense: further studies of living with chronic illness.

Williams GH, Jones IR.

Sociol Health Illn. 2017 Jun;39(5):653-658. doi: 10.1111/1467-9566.12608. No abstract available.

PMID:
28627721
18.

Age-Related Autonomous Aldosteronism.

Nanba K, Vaidya A, Williams GH, Zheng I, Else T, Rainey WE.

Circulation. 2017 Jul 25;136(4):347-355. doi: 10.1161/CIRCULATIONAHA.117.028201. Epub 2017 May 31.

19.

Renin Phenotypes Characterize Vascular Disease, Autonomous Aldosteronism, and Mineralocorticoid Receptor Activity.

Hundemer GL, Baudrand R, Brown JM, Curhan G, Williams GH, Vaidya A.

J Clin Endocrinol Metab. 2017 Jun 1;102(6):1835-1843. doi: 10.1210/jc.2016-3867.

20.

Regulation of aldosterone secretion by mineralocorticoid receptor-mediated signaling.

Chong C, Hamid A, Yao T, Garza AE, Pojoga LH, Adler GK, Romero JR, Williams GH.

J Endocrinol. 2017 Mar;232(3):525-534. doi: 10.1530/JOE-16-0452. Epub 2017 Jan 17.

21.

p53 controls CDC7 levels to reinforce G1 cell cycle arrest upon genotoxic stress.

Tudzarova S, Mulholland P, Dey A, Stoeber K, Okorokov AL, Williams GH.

Cell Cycle. 2016 Nov;15(21):2958-2972. Epub 2016 Sep 9.

22.

Caveolin 1 Modulates Aldosterone-Mediated Pathways of Glucose and Lipid Homeostasis.

Baudrand R, Gupta N, Garza AE, Vaidya A, Leopold JA, Hopkins PN, Jeunemaitre X, Ferri C, Romero JR, Williams J, Loscalzo J, Adler GK, Williams GH, Pojoga LH.

J Am Heart Assoc. 2016 Sep 28;5(10). pii: e003845. doi: 10.1161/JAHA.116.003845.

23.

Treatment with patiromer decreases aldosterone in patients with chronic kidney disease and hyperkalemia on renin-angiotensin system inhibitors.

Weir MR, Bakris GL, Gross C, Mayo MR, Garza D, Stasiv Y, Yuan J, Berman L, Williams GH.

Kidney Int. 2016 Sep;90(3):696-704. doi: 10.1016/j.kint.2016.04.019. Epub 2016 Jun 24.

24.

Cdc7 is a potent anti-cancer target in pancreatic cancer due to abrogation of the DNA origin activation checkpoint.

Huggett MT, Tudzarova S, Proctor I, Loddo M, Keane MG, Stoeber K, Williams GH, Pereira SP.

Oncotarget. 2016 Apr 5;7(14):18495-507. doi: 10.18632/oncotarget.7611.

25.

A prevalent caveolin-1 gene variant is associated with the metabolic syndrome in Caucasians and Hispanics.

Baudrand R, Goodarzi MO, Vaidya A, Underwood PC, Williams JS, Jeunemaitre X, Hopkins PN, Brown N, Raby BA, Lasky-Su J, Adler GK, Cui J, Guo X, Taylor KD, Chen YD, Xiang A, Raffel LJ, Buchanan TA, Rotter JI, Williams GH, Pojoga LH.

Metabolism. 2015 Dec;64(12):1674-81. doi: 10.1016/j.metabol.2015.09.005. Epub 2015 Sep 12.

26.

Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.

Baudrand R, Pojoga LH, Vaidya A, Garza AE, Vöhringer PA, Jeunemaitre X, Hopkins PN, Yao TM, Williams J, Adler GK, Williams GH.

Circulation. 2015 Nov 10;132(19):1825-33. doi: 10.1161/CIRCULATIONAHA.115.016759. Epub 2015 Oct 2.

27.

Patiromer induces rapid and sustained potassium lowering in patients with chronic kidney disease and hyperkalemia.

Bushinsky DA, Williams GH, Pitt B, Weir MR, Freeman MW, Garza D, Stasiv Y, Li E, Berman L, Bakris GL.

Kidney Int. 2015 Dec;88(6):1427-1433. doi: 10.1038/ki.2015.270. Epub 2015 Sep 16.

28.

Cooperative Role of Mineralocorticoid Receptor and Caveolin-1 in Regulating the Vascular Response to Low Nitric Oxide-High Angiotensin II-Induced Cardiovascular Injury.

Pojoga LH, Yao TM, Opsasnick LA, Siddiqui WT, Reslan OM, Adler GK, Williams GH, Khalil RA.

J Pharmacol Exp Ther. 2015 Oct;355(1):32-47. doi: 10.1124/jpet.115.226043. Epub 2015 Jul 16.

29.

Critical Role of Striatin in Blood Pressure and Vascular Responses to Dietary Sodium Intake.

Garza AE, Pojoga LH, Moize B, Hafiz WM, Opsasnick LA, Siddiqui WT, Horenstein M, Adler GK, Williams GH, Khalil RA.

Hypertension. 2015 Sep;66(3):674-80. doi: 10.1161/HYPERTENSIONAHA.115.05600. Epub 2015 Jul 13.

30.

Variants in striatin gene are associated with salt-sensitive blood pressure in mice and humans.

Garza AE, Rariy CM, Sun B, Williams J, Lasky-Su J, Baudrand R, Yao T, Moize B, Hafiz WM, Romero JR, Adler GK, Ferri C, Hopkins PN, Pojoga LH, Williams GH.

Hypertension. 2015 Jan;65(1):211-217. doi: 10.1161/HYPERTENSIONAHA.114.04233. Epub 2014 Nov 3.

31.

Estrogen receptor inhibits mineralocorticoid receptor transcriptional regulatory function.

Barrett Mueller K, Lu Q, Mohammad NN, Luu V, McCurley A, Williams GH, Adler GK, Karas RH, Jaffe IZ.

Endocrinology. 2014 Nov;155(11):4461-72. doi: 10.1210/en.2014-1270. Epub 2014 Jul 22.

32.

Pregnancy-associated plasma protein A regulates mitosis and is epigenetically silenced in breast cancer.

Loddo M, Andryszkiewicz J, Rodriguez-Acebes S, Stoeber K, Jones A, Dafou D, Apostolidou S, Wollenschlaeger A, Widschwendter M, Sainsbury R, Tudzarova S, Williams GH.

J Pathol. 2014 Aug;233(4):344-56. doi: 10.1002/path.4393.

PMID:
24931331
33.

Aldosterone dysregulation with aging predicts renal vascular function and cardiovascular risk.

Brown JM, Underwood PC, Ferri C, Hopkins PN, Williams GH, Adler GK, Vaidya A.

Hypertension. 2014 Jun;63(6):1205-11. doi: 10.1161/HYPERTENSIONAHA.114.03231. Epub 2014 Mar 24.

34.

Statins and musculoskeletal adverse events.

Baudrand R, Williams GH.

JAMA Intern Med. 2014 Feb 1;174(2):302-3. doi: 10.1001/jamainternmed.2013.12705. No abstract available.

PMID:
24493608
35.

Long-term dietary sodium restriction increases adiponectin expression and ameliorates the proinflammatory adipokine profile in obesity.

Baudrand R, Lian CG, Lian BQ, Ricchiuti V, Yao TM, Li J, Williams GH, Adler GK.

Nutr Metab Cardiovasc Dis. 2014 Jan;24(1):34-41. doi: 10.1016/j.numecd.2013.07.004. Epub 2013 Oct 12.

36.

Dissociation of hyperglycemia from altered vascular contraction and relaxation mechanisms in caveolin-1 null mice.

Pojoga LH, Yao TM, Opsasnick LA, Garza AE, Reslan OM, Adler GK, Williams GH, Khalil RA.

J Pharmacol Exp Ther. 2014 Feb;348(2):260-70. doi: 10.1124/jpet.113.209189. Epub 2013 Nov 26.

37.

Aldosterone's mechanism of action: roles of lysine-specific demethylase 1, caveolin and striatin.

Baudrand R, Pojoga LH, Romero JR, Williams GH.

Curr Opin Nephrol Hypertens. 2014 Jan;23(1):32-7. doi: 10.1097/01.mnh.0000436543.48391.e0. Review.

PMID:
24275769
38.

Predictors of plasma and urinary catecholamine levels in normotensive and hypertensive men and women.

Saxena AR, Chamarthi B, Williams GH, Hopkins PN, Seely EW.

J Hum Hypertens. 2014 May;28(5):292-7. doi: 10.1038/jhh.2013.112. Epub 2013 Nov 14.

39.

Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.

Brown JM, Williams JS, Luther JM, Garg R, Garza AE, Pojoga LH, Ruan DT, Williams GH, Adler GK, Vaidya A.

Hypertension. 2014 Feb;63(2):273-80. doi: 10.1161/HYPERTENSIONAHA.113.01910. Epub 2013 Nov 4.

40.

Effect of mineralocorticoid receptor antagonist on insulin resistance and endothelial function in obese subjects.

Garg R, Kneen L, Williams GH, Adler GK.

Diabetes Obes Metab. 2014 Mar;16(3):268-72. doi: 10.1111/dom.12224. Epub 2013 Oct 31.

41.

Abnormal aldosterone physiology and cardiometabolic risk factors.

Vaidya A, Underwood PC, Hopkins PN, Jeunemaitre X, Ferri C, Williams GH, Adler GK.

Hypertension. 2013 Apr;61(4):886-93. doi: 10.1161/HYPERTENSIONAHA.111.00662. Epub 2013 Feb 11.

42.

Subcellular proteomics reveals a role for nucleo-cytoplasmic trafficking at the DNA replication origin activation checkpoint.

Mulvey CM, Tudzarova S, Crawford M, Williams GH, Stoeber K, Godovac-Zimmermann J.

J Proteome Res. 2013 Mar 1;12(3):1436-53. doi: 10.1021/pr3010919. Epub 2013 Feb 6.

43.

The influence of sodium- and calcium-regulatory hormone interventions on adipocytokines in obesity and diabetes.

Vaidya A, Underwood PC, Annes JP, Sun B, Williams GH, Forman JP, Williams JS.

Metabolism. 2013 Apr;62(4):539-47. doi: 10.1016/j.metabol.2012.10.001. Epub 2012 Nov 9.

44.

Lysine-specific demethylase-1 modifies the age effect on blood pressure sensitivity to dietary salt intake.

Krug AW, Tille E, Sun B, Pojoga L, Williams J, Chamarthi B, Lichtman AH, Hopkins PN, Adler GK, Williams GH.

Age (Dordr). 2013 Oct;35(5):1809-20. doi: 10.1007/s11357-012-9480-0. Epub 2012 Oct 2.

45.

Effect of low dose mineralocorticoid receptor antagonist eplerenone on glucose and lipid metabolism in healthy adult males.

Krug AW, Stelzner L, Rao AD, Lichtman AH, Williams GH, Adler GK.

Metabolism. 2013 Mar;62(3):386-91. doi: 10.1016/j.metabol.2012.08.011. Epub 2012 Sep 21.

46.

Direct renin inhibition modulates insulin resistance in caveolin-1-deficient mice.

Chuengsamarn S, Garza AE, Krug AW, Romero JR, Adler GK, Williams GH, Pojoga LH.

Metabolism. 2013 Feb;62(2):275-81. doi: 10.1016/j.metabol.2012.07.013. Epub 2012 Sep 4.

47.

Nonmodulation as the mechanism for salt sensitivity of blood pressure in individuals with hypertension and type 2 diabetes mellitus.

Underwood PC, Chamarthi B, Williams JS, Vaidya A, Garg R, Adler GK, Grotzke MP, Staskus G, Wadwekar D, Hopkins PN, Ferri C, McCall A, McClain D, Williams GH.

J Clin Endocrinol Metab. 2012 Oct;97(10):3775-82. doi: 10.1210/jc.2012-2127. Epub 2012 Aug 3.

48.

Bladder cancer diagnosis and identification of clinically significant disease by combined urinary detection of Mcm5 and nuclear matrix protein 22.

Kelly JD, Dudderidge TJ, Wollenschlaeger A, Okoturo O, Burling K, Tulloch F, Halsall I, Prevost T, Prevost AT, Vasconcelos JC, Robson W, Leung HY, Vasdev N, Pickard RS, Williams GH, Stoeber K.

PLoS One. 2012;7(7):e40305. doi: 10.1371/journal.pone.0040305. Epub 2012 Jul 9.

49.

The mineralocorticoid receptor agonist, fludrocortisone, differentially inhibits pituitary-adrenal activity in humans with psychotic major depression.

Lembke A, Gomez R, Tenakoon L, Keller J, Cohen G, Williams GH, Kraemer FB, Schatzberg AF.

Psychoneuroendocrinology. 2013 Jan;38(1):115-21. doi: 10.1016/j.psyneuen.2012.05.006. Epub 2012 Jun 21.

50.

Different polymorphisms of the mineralocorticoid receptor gene are associated with either glucocorticoid or mineralocorticoid levels in hypertension.

Sun B, Chamarthi B, Williams JS, Krug AW, Lasky-Su J, Raby BA, Hopkins PN, Jeunemaitre X, Ferri C, Williams GH.

J Clin Endocrinol Metab. 2012 Sep;97(9):E1825-9. doi: 10.1210/jc.2012-1486. Epub 2012 Jun 20.

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