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Items: 1 to 50 of 317

1.

Multiplexed Charge Detection Mass Spectrometry for High-Throughput Single Ion Analysis of Large Molecules.

Harper CC, Elliott AG, Oltrogge LM, Savage DF, Williams ER.

Anal Chem. 2019 Jun 4;91(11):7458-7465. doi: 10.1021/acs.analchem.9b01669. Epub 2019 May 22.

PMID:
31082222
2.

Variation in assembly stoichiometry in non-metazoan homologs of the hub domain of Ca2+ /calmodulin-dependent protein kinase II.

McSpadden ED, Xia Z, Chi CC, Susa AC, Shah NH, Gee CL, Williams ER, Kuriyan J.

Protein Sci. 2019 Jun;28(6):1071-1082. doi: 10.1002/pro.3614. Epub 2019 Apr 17.

PMID:
30942928
3.

Native mass spectrometry beyond ammonium acetate: effects of nonvolatile salts on protein stability and structure.

Xia Z, DeGrandchamp JB, Williams ER.

Analyst. 2019 Apr 8;144(8):2565-2573. doi: 10.1039/c9an00266a.

PMID:
30882808
4.

Aerobic Exercise Improves Microvascular Function in Older Adults.

Hurley DM, Williams ER, Cross JM, Riedinger BR, Meyer RA, Abela GS, Slade JM.

Med Sci Sports Exerc. 2019 Apr;51(4):773-781. doi: 10.1249/MSS.0000000000001854.

PMID:
30489496
5.

Effect of droplet lifetime on where ions are formed in electrospray ionization.

Xia Z, Williams ER.

Analyst. 2018 Dec 17;144(1):237-248. doi: 10.1039/c8an01824c.

PMID:
30488074
6.

Effects of Individual Ion Energies on Charge Measurements in Fourier Transform Charge Detection Mass Spectrometry (FT-CDMS).

Elliott AG, Harper CC, Lin HW, Williams ER.

J Am Soc Mass Spectrom. 2019 Jun;30(6):946-955. doi: 10.1007/s13361-018-2094-8. Epub 2018 Nov 14.

PMID:
30430436
7.

Submicrometer Nanospray Emitters Provide New Insights into the Mechanism of Cation Adduction to Anionic Oligonucleotides.

Kenderdine T, Xia Z, Williams ER, Fabris D.

Anal Chem. 2018 Nov 20;90(22):13541-13548. doi: 10.1021/acs.analchem.8b03632. Epub 2018 Nov 5.

PMID:
30351906
8.

Contribution to the discussion of "When should meta-analysis avoid making hidden normality assumptions?" Using general-purpose GLMM software for meta-analysis.

Piepho HP, Madden LV, Williams ER.

Biom J. 2018 Nov;60(6):1059-1061. doi: 10.1002/bimj.201800096. Epub 2018 Aug 7. No abstract available.

PMID:
30085350
9.

Structural Investigation of the Hormone Melatonin and Its Alkali and Alkaline Earth Metal Complexes in the Gas Phase.

Chakrabarty S, DiTucci MJ, Berden G, Oomens J, Williams ER.

J Am Soc Mass Spectrom. 2018 Sep;29(9):1835-1847. doi: 10.1007/s13361-018-2020-0. Epub 2018 Jul 13.

PMID:
30006822
10.

Determining Energies and Cross Sections of Individual Ions Using Higher-Order Harmonics in Fourier Transform Charge Detection Mass Spectrometry (FT-CDMS).

Harper CC, Elliott AG, Lin HW, Williams ER.

J Am Soc Mass Spectrom. 2018 Sep;29(9):1861-1869. doi: 10.1007/s13361-018-1987-x. Epub 2018 Jun 2.

PMID:
29860679
11.

Competition between salt bridge and non-zwitterionic structures in deprotonated amino acid dimers.

Heiles S, Berden G, Oomens J, Williams ER.

Phys Chem Chem Phys. 2018 Jun 13;20(23):15641-15652. doi: 10.1039/c8cp01458b.

PMID:
29845141
12.

Long distance ion-water interactions in aqueous sulfate nanodrops persist to ambient temperatures in the upper atmosphere.

DiTucci MJ, Stachl CN, Williams ER.

Chem Sci. 2018 Apr 4;9(16):3970-3977. doi: 10.1039/c8sc00854j. eCollection 2018 Apr 28.

13.

Estimating the variance for heterogeneity in arm-based network meta-analysis.

Piepho HP, Madden LV, Roger J, Payne R, Williams ER.

Pharm Stat. 2018 May;17(3):264-277. doi: 10.1002/pst.1857. Epub 2018 Apr 19.

PMID:
29676023
14.

Hemolysis-induced Lung Vascular Leakage Contributes to the Development of Pulmonary Hypertension.

Rafikova O, Williams ER, McBride ML, Zemskova M, Srivastava A, Nair V, Desai AA, Langlais PR, Zemskov E, Simon M, Mandarino LJ, Rafikov R.

Am J Respir Cell Mol Biol. 2018 Sep;59(3):334-345. doi: 10.1165/rcmb.2017-0308OC.

PMID:
29652520
15.

Melting proteins confined in nanodroplets with 10.6 μm light provides clues about early steps of denaturation.

El-Baba TJ, Fuller DR, Woodall DW, Raab SA, Conant CR, Dilger JM, Toker Y, Williams ER, Russell DH, Clemmer DE.

Chem Commun (Camb). 2018 Mar 27;54(26):3270-3273. doi: 10.1039/c7cc09829d.

16.

How many human proteoforms are there?

Aebersold R, Agar JN, Amster IJ, Baker MS, Bertozzi CR, Boja ES, Costello CE, Cravatt BF, Fenselau C, Garcia BA, Ge Y, Gunawardena J, Hendrickson RC, Hergenrother PJ, Huber CG, Ivanov AR, Jensen ON, Jewett MC, Kelleher NL, Kiessling LL, Krogan NJ, Larsen MR, Loo JA, Ogorzalek Loo RR, Lundberg E, MacCoss MJ, Mallick P, Mootha VK, Mrksich M, Muir TW, Patrie SM, Pesavento JJ, Pitteri SJ, Rodriguez H, Saghatelian A, Sandoval W, Schlüter H, Sechi S, Slavoff SA, Smith LM, Snyder MP, Thomas PM, Uhlén M, Van Eyk JE, Vidal M, Walt DR, White FM, Williams ER, Wohlschlager T, Wysocki VH, Yates NA, Young NL, Zhang B.

Nat Chem Biol. 2018 Feb 14;14(3):206-214. doi: 10.1038/nchembio.2576.

17.

Controlled Dimerization of Mn12 Single-Molecule Magnets.

Jenkins TA, Garnero M, Corrales SA, Williams ER, Mowson AM, Ozarowski A, Wernsdorfer W, Christou G, Lampropoulos C.

Inorg Chem. 2017 Dec 18;56(24):14755-14758. doi: 10.1021/acs.inorgchem.7b02640. Epub 2017 Nov 27.

PMID:
29172478
18.

Single Particle Analyzer of Mass: A Charge Detection Mass Spectrometer with a Multi-Detector Electrostatic Ion Trap.

Elliott AG, Merenbloom SI, Chakrabarty S, Williams ER.

Int J Mass Spectrom. 2017 Mar;414:45-55. doi: 10.1016/j.ijms.2017.01.007. Epub 2017 Jan 15.

19.

Submicrometer Emitter ESI Tips for Native Mass Spectrometry of Membrane Proteins in Ionic and Nonionic Detergents.

Susa AC, Lippens JL, Xia Z, Loo JA, Campuzano IDG, Williams ER.

J Am Soc Mass Spectrom. 2018 Jan;29(1):203-206. doi: 10.1007/s13361-017-1793-x. Epub 2017 Oct 12.

20.

Protein-Glass Surface Interactions and Ion Desalting in Electrospray Ionization with Submicron Emitters.

Xia Z, Williams ER.

J Am Soc Mass Spectrom. 2018 Jan;29(1):194-202. doi: 10.1007/s13361-017-1825-6. Epub 2017 Oct 12.

PMID:
29027129
21.

Structural and electrostatic effects at the surfaces of size- and charge-selected aqueous nanodrops.

Cooper RJ, O'Brien JT, Chang TM, Williams ER.

Chem Sci. 2017 Jul 1;8(7):5201-5213. doi: 10.1039/c7sc00481h. Epub 2017 May 19.

22.

Characterizing the Conformationome: Toward a Structural Understanding of the Proteome.

Clemmer DE, Russell DH, Williams ER.

Acc Chem Res. 2017 Mar 21;50(3):556-560. doi: 10.1021/acs.accounts.6b00548.

PMID:
28945417
23.

Mass, mobility and MSn measurements of single ions using charge detection mass spectrometry.

Elliott AG, Harper CC, Lin HW, Williams ER.

Analyst. 2017 Jul 24;142(15):2760-2769. doi: 10.1039/c7an00618g.

PMID:
28636005
24.

Simultaneous Measurements of Mass and Collisional Cross-Section of Single Ions with Charge Detection Mass Spectrometry.

Elliott AG, Harper CC, Lin HW, Susa AC, Xia Z, Williams ER.

Anal Chem. 2017 Jul 18;89(14):7701-7708. doi: 10.1021/acs.analchem.7b01675. Epub 2017 Jun 30.

PMID:
28621517
25.

Native Mass Spectrometry from Common Buffers with Salts That Mimic the Extracellular Environment.

Susa AC, Xia Z, Williams ER.

Angew Chem Int Ed Engl. 2017 Jun 26;56(27):7912-7915. doi: 10.1002/anie.201702330. Epub 2017 Jun 5.

PMID:
28510995
26.

Sequential water molecule binding enthalpies for aqueous nanodrops containing a mono-, di- or trivalent ion and between 20 and 500 water molecules.

Heiles S, Cooper RJ, DiTucci MJ, Williams ER.

Chem Sci. 2017 Apr 1;8(4):2973-2982. doi: 10.1039/c6sc04957e. Epub 2017 Jan 26.

27.

Nanometer patterning of water by tetraanionic ferrocyanide stabilized in aqueous nanodrops.

DiTucci MJ, Williams ER.

Chem Sci. 2017 Feb 1;8(2):1391-1399. doi: 10.1039/c6sc03722d. Epub 2016 Oct 17.

28.

Collisional Cross-Sections with T-Wave Ion Mobility Spectrometry without Experimental Calibration.

Mortensen DN, Susa AC, Williams ER.

J Am Soc Mass Spectrom. 2017 Jul;28(7):1282-1292. doi: 10.1007/s13361-017-1669-0. Epub 2017 Apr 21.

PMID:
28432656
29.

Effects of multivalent hexacyanoferrates and their ion pairs on water molecule dynamics measured with terahertz spectroscopy.

DiTucci MJ, Böhm F, Schwaab G, Williams ER, Havenith M.

Phys Chem Chem Phys. 2017 Mar 8;19(10):7297-7306. doi: 10.1039/c6cp08423k.

PMID:
28239695
30.

Small Emitter Tips for Native Mass Spectrometry of Proteins and Protein Complexes from Nonvolatile Buffers That Mimic the Intracellular Environment.

Susa AC, Xia Z, Williams ER.

Anal Chem. 2017 Mar 7;89(5):3116-3122. doi: 10.1021/acs.analchem.6b04897. Epub 2017 Feb 22.

PMID:
28192954
31.

Using lysine adducts of human serum albumin to investigate the disposition of exogenous formaldehyde in human blood.

Regazzoni LG, Grigoryan H, Ji Z, Chen X, Daniels SI, Huang D, Sanchez S, Tang N, Sillé FC, Iavarone AT, Williams ER, Zhang L, Rappaport SM.

Toxicol Lett. 2017 Feb 15;268:26-35. doi: 10.1016/j.toxlet.2017.01.002. Epub 2017 Jan 16.

32.

Plastic Changes in Human Motor Cortical Output Induced by Random but not Closed-Loop Peripheral Stimulation: the Curse of Causality.

Brown KI, Williams ER, de Carvalho F, Baker SN.

Front Hum Neurosci. 2016 Nov 15;10:590. eCollection 2016.

33.

Adductomics Pipeline for Untargeted Analysis of Modifications to Cys34 of Human Serum Albumin.

Grigoryan H, Edmands W, Lu SS, Yano Y, Regazzoni L, Iavarone AT, Williams ER, Rappaport SM.

Anal Chem. 2016 Nov 1;88(21):10504-10512. Epub 2016 Oct 10.

34.

Charging of Proteins in Native Mass Spectrometry.

Susa AC, Xia Z, Tang HYH, Tainer JA, Williams ER.

J Am Soc Mass Spectrom. 2017 Feb;28(2):332-340. doi: 10.1007/s13361-016-1517-7. Epub 2016 Oct 12.

35.

The effect of halide and iodate anions on the hydrogen-bonding network of water in aqueous nanodrops.

Chakrabarty S, Williams ER.

Phys Chem Chem Phys. 2016 Sep 14;18(36):25483-25490.

PMID:
27711560
36.
37.

Surface-Induced Protein Unfolding in Submicron Electrospray Emitters.

Mortensen DN, Williams ER.

Anal Chem. 2016 Oct 4;88(19):9662-9668. Epub 2016 Sep 22.

PMID:
27615434
38.

Electrothermal supercharging of proteins in native MS: effects of protein isoelectric point, buffer, and nanoESI-emitter tip size.

Mortensen DN, Williams ER.

Analyst. 2016 Oct 7;141(19):5598-606. doi: 10.1039/c6an01380e. Epub 2016 Jul 21.

39.

Identification of a Minimal Peptide Tag for in Vivo and in Vitro Loading of Encapsulin.

Cassidy-Amstutz C, Oltrogge L, Going CC, Lee A, Teng P, Quintanilla D, East-Seletsky A, Williams ER, Savage DF.

Biochemistry. 2016 Jun 21;55(24):3461-8. doi: 10.1021/acs.biochem.6b00294. Epub 2016 Jun 7.

PMID:
27224728
40.

Molecular mechanism of activation-triggered subunit exchange in Ca(2+)/calmodulin-dependent protein kinase II.

Bhattacharyya M, Stratton MM, Going CC, McSpadden ED, Huang Y, Susa AC, Elleman A, Cao YM, Pappireddi N, Burkhardt P, Gee CL, Barros T, Schulman H, Williams ER, Kuriyan J.

Elife. 2016 Mar 7;5. pii: e13405. doi: 10.7554/eLife.13405.

41.

Real-time HD Exchange Kinetics of Proteins from Buffered Aqueous Solution with Electrothermal Supercharging and Top-Down Tandem Mass Spectrometry.

Going CC, Xia Z, Williams ER.

J Am Soc Mass Spectrom. 2016 Jun;27(6):1019-27. doi: 10.1007/s13361-016-1350-z. Epub 2016 Feb 26.

42.

Ultrafast (1 μs) Mixing and Fast Protein Folding in Nanodrops Monitored by Mass Spectrometry.

Mortensen DN, Williams ER.

J Am Chem Soc. 2016 Mar 16;138(10):3453-60. doi: 10.1021/jacs.5b13081. Epub 2016 Mar 2.

PMID:
26902747
43.

Delayed Onset of Crystallinity in Ion-Containing Aqueous Nanodrops.

Cooper RJ, DiTucci MJ, Chang TM, Williams ER.

J Am Chem Soc. 2016 Jan 13;138(1):96-9. doi: 10.1021/jacs.5b11880. Epub 2015 Dec 31.

PMID:
26714195
44.

A Leadless Intracardiac Transcatheter Pacing System.

Reynolds D, Duray GZ, Omar R, Soejima K, Neuzil P, Zhang S, Narasimhan C, Steinwender C, Brugada J, Lloyd M, Roberts PR, Sagi V, Hummel J, Bongiorni MG, Knops RE, Ellis CR, Gornick CC, Bernabei MA, Laager V, Stromberg K, Williams ER, Hudnall JH, Ritter P; Micra Transcatheter Pacing Study Group.

N Engl J Med. 2016 Feb 11;374(6):533-41. doi: 10.1056/NEJMoa1511643. Epub 2015 Nov 9.

45.

Hydrogen bond mediated stabilization of the salt bridge structure for the glycine dimer anion.

Heiles S, Cooper RJ, Berden G, Oomens J, Williams ER.

Phys Chem Chem Phys. 2015 Nov 11;17(45):30642-7. doi: 10.1039/c5cp06120b.

PMID:
26524433
46.

The start of lightning: Evidence of bidirectional lightning initiation.

Montanyà J, van der Velde O, Williams ER.

Sci Rep. 2015 Oct 16;5:15180. doi: 10.1038/srep15180.

47.

New supercharging reagents produce highly charged protein ions in native mass spectrometry.

Going CC, Xia Z, Williams ER.

Analyst. 2015 Nov 7;140(21):7184-94. doi: 10.1039/c5an01710f.

48.

Molecular hydrogen messengers can lead to structural infidelity: A cautionary tale of protonated glycine.

Masson A, Williams ER, Rizzo TR.

J Chem Phys. 2015 Sep 14;143(10):104313. doi: 10.1063/1.4930196.

PMID:
26374041
49.

Effects of electronic structure on the hydration of PbNO3(+) and SrNO3(+) ion pairs.

Cooper RJ, Heiles S, Williams ER.

Phys Chem Chem Phys. 2015 Jun 28;17(24):15963-75. doi: 10.1039/c5cp01859e. Epub 2015 Jun 1.

PMID:
26028325
50.

Hydration of guanidinium depends on its local environment.

Heiles S, Cooper RJ, DiTucci MJ, Williams ER.

Chem Sci. 2015 Jun 1;6(6):3420-3429. doi: 10.1039/c5sc00618j. Epub 2015 Apr 14.

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