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Varespladib (LY315920) and Methyl Varespladib (LY333013) Abrogate or Delay Lethality Induced by Presynaptically Acting Neurotoxic Snake Venoms.

Gutiérrez JM, Lewin MR, Williams DJ, Lomonte B.

Toxins (Basel). 2020 Feb 20;12(2). pii: E131. doi: 10.3390/toxins12020131.


Vaccination Status and Adherence to Quality Measures for Acute Respiratory Tract Illnesses.

Bryan MA, Hofstetter AM, Simon TD, Zhou C, Williams DJ, Tyler A, Kenyon CC, Vachani JG, Opel DJ, Mangione-Smith R.

Hosp Pediatr. 2020 Feb 10. pii: hpeds.2019-0245. doi: 10.1542/hpeds.2019-0245. [Epub ahead of print]


The Epidemiology and Control of Liver Flukes in Cattle and Sheep.

Howell AK, Williams DJL.

Vet Clin North Am Food Anim Pract. 2020 Mar;36(1):109-123. doi: 10.1016/j.cvfa.2019.12.002. Review.


Clinical Features of Human Metapneumovirus-Associated Community-Acquired Pneumonia Hospitalizations.

Howard LM, Edwards KM, Zhu Y, Grijalva CG, Self WH, Jain S, Ampofo K, Pavia AT, Arnold SR, McCullers JA, Anderson EJ, Wunderink RG, Williams DJ.

Clin Infect Dis. 2020 Feb 3. pii: ciaa088. doi: 10.1093/cid/ciaa088. [Epub ahead of print]


Distributed automated manufacturing of pluripotent stem cell products.

Shariatzadeh M, Chandra A, Wilson SL, McCall MJ, Morizur L, Lesueur L, Chose O, Gepp MM, Schulz A, Neubauer JC, Zimmermann H, Abranches E, Man J, O'Shea O, Stacey G, Hewitt Z, Williams DJ.

Int J Adv Manuf Technol. 2020;106(3):1085-1103. doi: 10.1007/s00170-019-04516-1. Epub 2019 Dec 4.


A Risk Score Including Carotid Plaque Inflammation and Stenosis Severity Improves Identification of Recurrent Stroke.

Kelly PJ, Camps-Renom P, Giannotti N, Martí-Fàbregas J, McNulty JP, Baron JC, Barry M, Coutts SB, Cronin S, Delgado-Mederos R, Dolan E, Fernández-León A, Foley S, Harbison J, Horgan G, Kavanagh E, Marnane M, McCabe J, McDonnell C, Sharma VK, Williams DJ, O'Connell M, Murphy S.

Stroke. 2020 Mar;51(3):838-845. doi: 10.1161/STROKEAHA.119.027268. Epub 2020 Jan 17.


Family history of pre-eclampsia and cardiovascular disease as risk factors for pre-eclampsia: the GenPE case-control study.

Serrano NC, Quintero-Lesmes DC, Dudbridge F, Leon LJ, Hingorani AD, Williams DJ, Casas JP.

Hypertens Pregnancy. 2020 Feb;39(1):56-63. doi: 10.1080/10641955.2019.1704003. Epub 2020 Jan 7.


Co-infection of cattle with Fasciola hepatica or F. gigantica and Mycobacterium bovis: A systematic review.

Howell AK, McCann CM, Wickstead F, Williams DJL.

PLoS One. 2019 Dec 30;14(12):e0226300. doi: 10.1371/journal.pone.0226300. eCollection 2019.


A family of Type VI secretion system effector proteins that form ion-selective pores.

Mariano G, Trunk K, Williams DJ, Monlezun L, Strahl H, Pitt SJ, Coulthurst SJ.

Nat Commun. 2019 Dec 2;10(1):5484. doi: 10.1038/s41467-019-13439-0.


Establishing the variation of blood metrics within UK Biobank to inform cell therapy manufacturing processes.

Thurman-Newell J, Petzing J, Williams DJ.

Regen Med. 2019 Nov;14(11):1029-1046. doi: 10.2217/rme-2018-0168. Epub 2019 Nov 13.


The status of three species names in the mealybug genus Rastrococcus Ferris (Hemiptera: Coccomorpha: Pseudococcidae).

Williams DJ.

Zootaxa. 2019 Mar 11;4565(3):zootaxa.4565.3.11. doi: 10.11646/zootaxa.4565.3.11.


Pravastatin for early-onset pre-eclampsia: a randomised, blinded, placebo-controlled trial.

Ahmed A, Williams DJ, Cheed V, Middleton LJ, Ahmad S, Wang K, Vince AT, Hewett P, Spencer K, Khan KS, Daniels JP; StAmP trial Collaborative Group.

BJOG. 2020 Mar;127(4):478-488. doi: 10.1111/1471-0528.16013. Epub 2019 Dec 14.


A clinically applicable tool for rapidly estimating muscle volume using ultrasound images.

Rothwell DT, Fong DTP, Stapley SA, Williams DJ.

Eur J Appl Physiol. 2019 Dec;119(11-12):2685-2699. doi: 10.1007/s00421-019-04242-2. Epub 2019 Oct 25.


Cognitive impairment and medication adherence post-stroke: A five-year follow-up of the ASPIRE-S cohort.

Rohde D, Gaynor E, Large M, Mellon L, Bennett K, Williams DJ, Brewer L, Hall P, Callaly E, Dolan E, Hickey A.

PLoS One. 2019 Oct 17;14(10):e0223997. doi: 10.1371/journal.pone.0223997. eCollection 2019.


Outlining progress since the first International Snakebite Awareness Day and some key challenges for next year.

Harrison RA, Williams DJ.

Trans R Soc Trop Med Hyg. 2019 Oct 11;113(10):577-578. doi: 10.1093/trstmh/trz096. No abstract available.


Clinical Progress Note: Procalcitonin in the Management of Pediatric Lower Respiratory Tract Infection.

Katz SE, Sartori LF, Williams DJ.

J Hosp Med. 2019 Nov 1;14(10):688-690. doi: 10.12788/jhm.3301. Epub 2019 Sep 18. No abstract available.


Predictors of Bacteremia in Children Hospitalized With Community-Acquired Pneumonia.

Lipsett SC, Hall M, Ambroggio L, Desai S, Shah SS, Brogan TV, Hersh AL, Williams DJ, Grijalva CG, Gerber JS, Blaschke AJ, Neuman MI.

Hosp Pediatr. 2019 Oct;9(10):770-778. doi: 10.1542/hpeds.2019-0149. Epub 2019 Sep 13.


Ciliary exclusion of Polycystin-2 promotes kidney cystogenesis in an autosomal dominant polycystic kidney disease model.

Walker RV, Keynton JL, Grimes DT, Sreekumar V, Williams DJ, Esapa C, Wu D, Knight MM, Norris DP.

Nat Commun. 2019 Sep 6;10(1):4072. doi: 10.1038/s41467-019-12067-y.


Parenteral Antibiotic Therapy Duration in Young Infants With Bacteremic Urinary Tract Infections.

Desai S, Aronson PL, Shabanova V, Neuman MI, Balamuth F, Pruitt CM, DePorre AG, Nigrovic LE, Rooholamini SN, Wang ME, Marble RD, Williams DJ, Sartori L, Leazer RC, Mitchell C, Shah SS; FEBRILE YOUNG INFANT RESEARCH COLLABORATIVE.

Pediatrics. 2019 Sep;144(3). pii: e20183844. doi: 10.1542/peds.2018-3844. Epub 2019 Aug 20.


Adverse Effects Profile of Dicycloplatin (DCP) Offers Chemotherapeutic Advantage Over Cisplatin and Carboplatin.

Yu JJ, Hogan T, Morley C, Crigger C, Jiao S, Williams DJ, Salkini MW, Yang X, Liang X, Yan B, Cecil C, Winn AC, Zheng J, Guo YI, Jiang BH, Washington IM.

Anticancer Res. 2019 Aug;39(8):4455-4462. doi: 10.21873/anticanres.13618.


Pediatric Respiratory Illness Measurement System (PRIMES) Scores and Outcomes.

Mangione-Smith R, Zhou C, Williams DJ, Johnson DP, Kenyon CC, Tyler A, Quinonez R, Vachani J, McGalliard J, Tieder JS, Simon TD, Wilson KM; Pediatric Research in Inpatient Settings (PRIS) Network.

Pediatrics. 2019 Aug;144(2). pii: e20190242. doi: 10.1542/peds.2019-0242.


Citizen science could map snakebite risk.

Ruiz de Castañeda R, Grey F, Williams DJ.

Nature. 2019 Jul;571(7766):478. doi: 10.1038/d41586-019-02247-7. No abstract available.


Systematic review and meta-analysis of the prevalence of cognitive impairment no dementia in the first year post-stroke.

Sexton E, McLoughlin A, Williams DJ, Merriman NA, Donnelly N, Rohde D, Hickey A, Wren MA, Bennett K.

Eur Stroke J. 2019 Jun;4(2):160-171. doi: 10.1177/2396987318825484. Epub 2019 Jan 16.


Agreement Between Two Procalcitonin Assays in Hospitalized Children.

Katz SE, Sartori LF, Szeles A, McHenry R, Stanford JE, Xu M, Colby JM, Halasa N, Williams DJ, Banerjee R.

Infect Dis Ther. 2019 Sep;8(3):463-468. doi: 10.1007/s40121-019-0250-5. Epub 2019 Jun 29.


Fasciola hepatica in UK horses.

Howell AK, Malalana F, Beesley NJ, Hodgkinson JE, Rhodes H, Sekiya M, Archer D, Clough HE, Gilmore P, Williams DJL.

Equine Vet J. 2020 Mar;52(2):194-199. doi: 10.1111/evj.13149. Epub 2019 Jul 21.


A review of our current understanding of parasite survival in silage and stored forages, with a focus on Fasciola hepatica metacercariae.

John BC, Davies DR, Williams DJL, Hodgkinson JE.

Grass Forage Sci. 2019 Jun;74(2):211-217. doi: 10.1111/gfs.12429. Epub 2019 May 7. Review.


Prevalence, Risk Factors, and Outcomes of Bacteremic Pneumonia in Children.

Fritz CQ, Edwards KM, Self WH, Grijalva CG, Zhu Y, Arnold SR, McCullers JA, Ampofo K, Pavia AT, Wunderink RG, Anderson EJ, Bramley AM, Jain S, Williams DJ.

Pediatrics. 2019 Jul;144(1). pii: e20183090. doi: 10.1542/peds.2018-3090.


The management of risk and investment in cell therapy process development: a case study for neurodegenerative disease.

Sebastian S, Hourd P, Chandra A, Williams DJ, Medcalf N.

Regen Med. 2019 May;14(5):465-488. doi: 10.2217/rme-2018-0081. Epub 2019 Jun 18.


A Prediction Model to Identify Febrile Infants ≤60 Days at Low Risk of Invasive Bacterial Infection.

Aronson PL, Shabanova V, Shapiro ED, Wang ME, Nigrovic LE, Pruitt CM, DePorre AG, Leazer RC, Desai S, Sartori LF, Marble RD, Rooholamini SN, McCulloh RJ, Woll C, Balamuth F, Alpern ER, Shah SS, Williams DJ, Browning WL, Shah N, Neuman MI; Febrile Young Infant Research Collaborative.

Pediatrics. 2019 Jul;144(1). pii: e20183604. doi: 10.1542/peds.2018-3604. Epub 2019 Jun 5.


Cerebral microbleeds and stroke risk after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies.

Wilson D, Ambler G, Lee KJ, Lim JS, Shiozawa M, Koga M, Li L, Lovelock C, Chabriat H, Hennerici M, Wong YK, Mak HKF, Prats-Sánchez L, Martínez-Domeño A, Inamura S, Yoshifuji K, Arsava EM, Horstmann S, Purrucker J, Lam BYK, Wong A, Kim YD, Song TJ, Schrooten M, Lemmens R, Eppinger S, Gattringer T, Uysal E, Tanriverdi Z, Bornstein NM, Assayag EB, Hallevi H, Tanaka J, Hara H, Coutts SB, Hert L, Polymeris A, Seiffge DJ, Lyrer P, Algra A, Kappelle J, Al-Shahi Salman R, Jäger HR, Lip GYH, Mattle HP, Panos LD, Mas JL, Legrand L, Karayiannis C, Phan T, Gunkel S, Christ N, Abrigo J, Leung T, Chu W, Chappell F, Makin S, Hayden D, Williams DJ, Kooi ME, van Dam-Nolen DHK, Barbato C, Browning S, Wiegertjes K, Tuladhar AM, Maaijwee N, Guevarra C, Yatawara C, Mendyk AM, Delmaire C, Köhler S, van Oostenbrugge R, Zhou Y, Xu C, Hilal S, Gyanwali B, Chen C, Lou M, Staals J, Bordet R, Kandiah N, de Leeuw FE, Simister R, van der Lugt A, Kelly PJ, Wardlaw JM, Soo Y, Fluri F, Srikanth V, Calvet D, Jung S, Kwa VIH, Engelter ST, Peters N, Smith EE, Yakushiji Y, Orken DN, Fazekas F, Thijs V, Heo JH, Mok V, Veltkamp R, Ay H, Imaizumi T, Gomez-Anson B, Lau KK, Jouvent E, Rothwell PM, Toyoda K, Bae HJ, Marti-Fabregas J, Werring DJ; Microbleeds International Collaborative Network.

Lancet Neurol. 2019 Jul;18(7):653-665. doi: 10.1016/S1474-4422(19)30197-8. Epub 2019 May 23. Erratum in: Lancet Neurol. 2019 Sep;18(9):e8. Lancet Neurol. 2020 Feb;19(2):e2.


Refugia and anthelmintic resistance: Concepts and challenges.

Hodgkinson JE, Kaplan RM, Kenyon F, Morgan ER, Park AW, Paterson S, Babayan SA, Beesley NJ, Britton C, Chaudhry U, Doyle SR, Ezenwa VO, Fenton A, Howell SB, Laing R, Mable BK, Matthews L, McIntyre J, Milne CE, Morrison TA, Prentice JC, Sargison ND, Williams DJL, Wolstenholme AJ, Devaney E.

Int J Parasitol Drugs Drug Resist. 2019 Aug;10:51-57. doi: 10.1016/j.ijpddr.2019.05.001. Epub 2019 May 17. Review.


Measuring muscle size and symmetry in healthy adult males using a time-efficient analysis of magnetic resonance images.

Rothwell DT, Williams DJ, Furlong LM.

Physiol Meas. 2019 Jul 3;40(6):064005. doi: 10.1088/1361-6579/ab2323.


First year post-stroke healthcare costs and fall-status among those discharged to the community.

Walsh ME, Sorensen J, Galvin R, Williams DJ, Harbison JA, Murphy S, Collins R, McCabe DJ, Crowe M, Horgan NF.

Eur Stroke J. 2018 Sep;3(3):254-262. doi: 10.1177/2396987318764954. Epub 2018 Mar 15.


Falls-Related EvEnts in the first year after StrokE in Ireland: Results of the multi-centre prospective FREESE cohort study.

Walsh ME, Galvin R, Williams DJ, Harbison JA, Murphy S, Collins R, McCabe DJ, Crowe M, Horgan NF.

Eur Stroke J. 2018 Sep;3(3):246-253. doi: 10.1177/2396987318764961. Epub 2018 Mar 16.


"I'm just not a Sudoku person": analysis of stroke survivor, carer, and healthcare professional perspectives for the design of a cognitive rehabilitation intervention.

Merriman NA, Bruen C, Gorman A, Horgan F, Williams DJ, Pender N, Byrne E, Hickey A.

Disabil Rehabil. 2019 Apr 11:1-11. doi: 10.1080/09638288.2019.1594400. [Epub ahead of print]


Home Smoke Exposure and Health-Related Quality of Life in Children with Acute Respiratory Illness.

Johnson J, Wilson KM, Zhou C, Johnson DP, Kenyon CC, Tieder JS, Dean A, Mangione-Smith R, Williams DJ.

J Hosp Med. 2019 Apr;14(4):212-217. doi: 10.12788/jhm.3164.


Coagulotoxic effects by brown snake (Pseudonaja) and taipan (Oxyuranus) venoms, and the efficacy of a new antivenom.

Zdenek CN, Hay C, Arbuckle K, Jackson TNW, Bos MHA, Op den Brouw B, Debono J, Allen L, Dunstan N, Morley T, Herrera M, Gutiérrez JM, Williams DJ, Fry BG.

Toxicol In Vitro. 2019 Aug;58:97-109. doi: 10.1016/j.tiv.2019.03.031. Epub 2019 Mar 22.


Stroke survivor cognitive decline and psychological wellbeing of family caregivers five years post-stroke: a cross-sectional analysis.

Rohde D, Gaynor E, Large M, Conway O, Bennett K, Williams DJ, Callaly E, Dolan E, Hickey A.

Top Stroke Rehabil. 2019 Apr;26(3):180-186. doi: 10.1080/10749357.2019.1590972. Epub 2019 Mar 23.


Addressing cognitive impairment following stroke: systematic review and meta-analysis of non-randomised controlled studies of psychological interventions.

Merriman NA, Sexton E, McCabe G, Walsh ME, Rohde D, Gorman A, Jeffares I, Donnelly NA, Pender N, Williams DJ, Horgan F, Doyle F, Wren MA, Bennett KE, Hickey A.

BMJ Open. 2019 Feb 27;9(2):e024429. doi: 10.1136/bmjopen-2018-024429.


Strategy for a globally coordinated response to a priority neglected tropical disease: Snakebite envenoming.

Williams DJ, Faiz MA, Abela-Ridder B, Ainsworth S, Bulfone TC, Nickerson AD, Habib AG, Junghanss T, Fan HW, Turner M, Harrison RA, Warrell DA.

PLoS Negl Trop Dis. 2019 Feb 21;13(2):e0007059. doi: 10.1371/journal.pntd.0007059. eCollection 2019 Feb. No abstract available.


A Clinical Prediction Algorithm to Stratify Pediatric Musculoskeletal Infection by Severity.

Benvenuti MA, An TJ, Mignemi ME, Martus JE, Mencio GA, Lovejoy SA, Schoenecker JG, Williams DJ.

J Pediatr Orthop. 2019 Mar;39(3):153-157. doi: 10.1097/BPO.0000000000000880.


Composite Fasciola hepatica faecal egg sedimentation test for cattle.

Graham-Brown J, Williams DJL, Skuce P, Zadoks RN, Dawes S, Swales H, Van Dijk J.

Vet Rec. 2019 May 11;184(19):589. doi: 10.1136/vr.105128. Epub 2019 Feb 2.


Drying-Rewetting Cycles Affect Nitrate Removal Rates in Woodchip Bioreactors.

Maxwell BM, Birgand F, Schipper LA, Christianson LE, Tian S, Helmers MJ, Williams DJ, Chescheir GM, Youssef MA.

J Environ Qual. 2019 Jan;48(1):93-101. doi: 10.2134/jeq2018.05.0199.


Rates of reported codeine-related poisonings and codeine prescribing following new national guidance in Ireland.

Kennedy C, Duggan E, Bennett K, Williams DJ.

Pharmacoepidemiol Drug Saf. 2019 Jan;28(1):106-111. doi: 10.1002/pds.4725. Epub 2019 Jan 9.


Assessing the performance of a Fasciola gigantica serum antibody ELISA to estimate prevalence in cattle in Cameroon.

Kelly RF, Mazeri S, Hartley C, Hamman SM, Ngu Ngwa V, Nkongho EF, Tanya V, Sander M, Ndip L, Morgan KL, Muwonge A, Handel I, de Bronsvoort BMC, Williams DJL.

BMC Vet Res. 2019 Jan 3;15(1):8. doi: 10.1186/s12917-018-1762-z.


Identifying hospital-acquired infections using retrospective record review from the Irish National Adverse Events Study (INAES) and European point prevalence survey case definitions.

Rafter N, Finn R, Burns K, Condell S, Conroy RM, Hickey A, O'Connor P, Vaughan D, Walsh G, Williams DJ.

J Hosp Infect. 2019 Mar;101(3):313-319. doi: 10.1016/j.jhin.2018.12.011. Epub 2018 Dec 24.


Low Admission Plasma Gelsolin Concentrations Identify Community-acquired Pneumonia Patients at High Risk for Severe Outcomes.

Self WH, Wunderink RG, DiNubile MJ, Stossel TP, Levinson SL, Williams DJ, Anderson EJ, Bramley AM, Jain S, Edwards KM, Grijalva CG.

Clin Infect Dis. 2019 Sep 13;69(7):1218-1225. doi: 10.1093/cid/ciy1049.


Serological response to influenza vaccination among adults hospitalized with community-acquired pneumonia.

Pratt CQ, Zhu Y, Grijalva CG, Wunderink RG, Mark Courtney D, Waterer G, Levine MZ, Jefferson S, Self WH, Williams DJ, Finelli L, Bramley AM, Edwards KM, Jain S, Anderson EJ.

Influenza Other Respir Viruses. 2019 Mar;13(2):208-212. doi: 10.1111/irv.12622. Epub 2018 Dec 17.


A Stem Cell-Based Screening Platform Identifies Compounds that Desensitize Motor Neurons to Endoplasmic Reticulum Stress.

Thams S, Lowry ER, Larraufie MH, Spiller KJ, Li H, Williams DJ, Hoang P, Jiang E, Williams LA, Sandoe J, Eggan K, Lieberam I, Kanning KC, Stockwell BR, Henderson CE, Wichterle H.

Mol Ther. 2019 Jan 2;27(1):87-101. doi: 10.1016/j.ymthe.2018.10.010. Epub 2018 Oct 19.

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