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Items: 1 to 50 of 860

1.

Biologically active marine natural products and their molecular targets discovered using a chemical genetics approach.

Williams DE, Andersen RJ.

Nat Prod Rep. 2019 Nov 21. doi: 10.1039/c9np00054b. [Epub ahead of print] Review.

PMID:
31750842
2.

Antifeedant, contact toxicity and oviposition deterrent effects of phyllostine acetate and phyllostine isolated from the endophytic fungus Diaporthe miriciae against Plutella xylostella larvae.

Ratnaweera PB, Jayasundara JMNM, Herath HHMSD, Williams DE, Rajapaksha SU, Nishantha KMDWP, de Silva ED, Andersen RJ.

Pest Manag Sci. 2019 Nov 6. doi: 10.1002/ps.5673. [Epub ahead of print]

PMID:
31696600
3.

Chinese scientists and US leadership in the life sciences.

Holtzman SH, Cohen R, Levin JM, Maraganore J; Signatories to the Statement.

Nat Biotechnol. 2019 Nov;37(11):1261-1263. doi: 10.1038/s41587-019-0285-x. No abstract available.

PMID:
31582856
4.

Low Cost Sensor Networks: How Do We Know the Data Are Reliable?

Williams DE.

ACS Sens. 2019 Oct 25;4(10):2558-2565. doi: 10.1021/acssensors.9b01455. Epub 2019 Sep 25.

PMID:
31523961
5.

Computational aberration correction of VIS-NIR multispectral imaging microscopy based on Fourier ptychography.

Shen C, Chan ACS, Chung J, Williams DE, Hajimiri A, Yang C.

Opt Express. 2019 Sep 2;27(18):24923-24937. doi: 10.1364/OE.27.024923.

PMID:
31510373
6.

Long-distance effects of epidemics: Assessing the link between the 2014 West Africa Ebola outbreak and U.S. exports and employment.

Kostova D, Cassell CH, Redd JT, Williams DE, Singh T, Martel LD, Bunnell RE.

Health Econ. 2019 Nov;28(11):1248-1261. doi: 10.1002/hec.3938. Epub 2019 Aug 28.

7.

What drives phenotypic divergence among coral clonemates of Acropora palmata?

Durante MK, Baums IB, Williams DE, Vohsen S, Kemp DW.

Mol Ecol. 2019 Jul;28(13):3208-3224. doi: 10.1111/mec.15140. Epub 2019 Jul 7.

PMID:
31282031
8.

Sulforaphane Bioavailability and Chemopreventive Activity in Men Presenting for Biopsy of the Prostate Gland: A Randomized Controlled Trial.

Zhang Z, Garzotto M, Davis EW 2nd, Mori M, Stoller WA, Farris PE, Wong CP, Beaver LM, Thomas GV, Williams DE, Dashwood RH, Hendrix DA, Ho E, Shannon J.

Nutr Cancer. 2019 Jun 1:1-14. doi: 10.1080/01635581.2019.1619783. [Epub ahead of print]

PMID:
31155953
9.

Genotypic variation in disease susceptibility among cultured stocks of elkhorn and staghorn corals.

Miller MW, Colburn PJ, Pontes E, Williams DE, Bright AJ, Serrano XM, Peters EC.

PeerJ. 2019 Apr 8;7:e6751. doi: 10.7717/peerj.6751. eCollection 2019.

10.

Mycenolide A, new butenolide from a marine sediment-derived bacterium Streptomyces sp. 4054.

de Oliveira JAM, Williams DE, Andersen RJ, Sarragiotto MH, Baldoqui DC.

Nat Prod Res. 2019 Apr 9:1-4. doi: 10.1080/14786419.2019.1597351. [Epub ahead of print]

PMID:
30964338
11.

Tracing MYC Expression for Small Molecule Discovery.

Steinberger J, Robert F, Hallé M, Williams DE, Cencic R, Sawhney N, Pelletier D, Williams P, Igarashi Y, Porco JA Jr, Rodriguez AD, Kopp B, Bachmann B, Andersen RJ, Pelletier J.

Cell Chem Biol. 2019 May 16;26(5):699-710.e6. doi: 10.1016/j.chembiol.2019.02.007. Epub 2019 Mar 14.

PMID:
30880156
12.

Metal-Assisted Hydrolysis Reactions Involving Lipids: A Review.

Williams DE, Grant KB.

Front Chem. 2019 Feb 19;7:14. doi: 10.3389/fchem.2019.00014. eCollection 2019. Review.

13.

High-Throughput "FP-Tag" Assay for the Identification of Glycosyltransferase Inhibitors.

Gao Z, Ovchinnikova OG, Huang BS, Liu F, Williams DE, Andersen RJ, Lowary TL, Whitfield C, Withers SG.

J Am Chem Soc. 2019 Feb 13;141(6):2201-2204. doi: 10.1021/jacs.8b10940. Epub 2019 Feb 1.

PMID:
30698425
14.

Stable isotope feeding studies reveal a steroid 5(6→7)abeo ring contraction biogenesis for the antibiotic solanioic acid produced by cultures of the fungus Rhizoctonia solani.

Mohamad-Ramshan R, Ratnaweera PB, Williams DE, de Silva ED, Andersen RJ.

J Antibiot (Tokyo). 2019 Apr;72(4):246-251. doi: 10.1038/s41429-018-0137-9. Epub 2019 Jan 11.

PMID:
30635614
15.

Toxicokinetics of benzo[a]pyrene in humans: Extensive metabolism as determined by UPLC-accelerator mass spectrometry following oral micro-dosing.

Madeen E, Siddens LK, Uesugi S, McQuistan T, Corley RA, Smith J, Waters KM, Tilton SC, Anderson KA, Ognibene T, Turteltaub K, Williams DE.

Toxicol Appl Pharmacol. 2019 Feb 1;364:97-105. doi: 10.1016/j.taap.2018.12.010. Epub 2018 Dec 21.

PMID:
30582946
16.

Towards Understanding the Molecular Basis of Nitric Oxide-Regulated Group Behaviors in Pathogenic Bacteria.

Williams DE, Boon EM.

J Innate Immun. 2019;11(3):205-215. doi: 10.1159/000494740. Epub 2018 Dec 17. Review.

17.

Identifying High-Risk Individuals for Chronic Kidney Disease: Results of the CHERISH Community Demonstration Project.

Burrows NR, Vassalotti JA, Saydah SH, Stewart R, Gannon M, Chen SC, Li S, Pederson S, Collins AJ, Williams DE.

Am J Nephrol. 2018;48(6):447-455. doi: 10.1159/000495082. Epub 2018 Nov 23.

PMID:
30472707
18.

Thyroid Peroxidase as an Autoantigen in Hashimoto's Disease: Structure, Function, and Antigenicity.

Williams DE, Le SN, Godlewska M, Hoke DE, Buckle AM.

Horm Metab Res. 2018 Dec;50(12):908-921. doi: 10.1055/a-0717-5514. Epub 2018 Oct 25. Review.

PMID:
30360003
19.

Bromopyrrole Alkaloid Inhibitors of the Proteasome Isolated from a Dictyonella sp. Marine Sponge Collected at the Amazon River Mouth.

de Souza RTMP, Freire VF, Gubiani JR, Ferreira RO, Trivella DBB, Moraes FC, Paradas WC, Salgado LT, Pereira RC, Amado Filho GM, Ferreira AG, Williams DE, Andersen RJ, Molinski TF, Berlinck RGS.

J Nat Prod. 2018 Oct 26;81(10):2296-2300. doi: 10.1021/acs.jnatprod.8b00533. Epub 2018 Oct 3.

PMID:
30281303
20.

Isolation, synthesis and bioactivity studies of phomactin terpenoids.

Kuroda Y, Nicacio KJ, da Silva-Jr IA, Leger PR, Chang S, Gubiani JR, Deflon VM, Nagashima N, Rode A, Blackford K, Ferreira AG, Sette LD, Williams DE, Andersen RJ, Jancar S, Berlinck RGS, Sarpong R.

Nat Chem. 2018 Sep;10(9):938-945. doi: 10.1038/s41557-018-0084-x. Epub 2018 Jul 30.

PMID:
30061613
21.

Persistence of Ebola virus after the end of widespread transmission in Liberia: an outbreak report.

Dokubo EK, Wendland A, Mate SE, Ladner JT, Hamblion EL, Raftery P, Blackley DJ, Laney AS, Mahmoud N, Wayne-Davies G, Hensley L, Stavale E, Fakoli L, Gregory C, Chen TH, Koryon A, Roth Allen D, Mann J, Hickey A, Saindon J, Badini M, Baller A, Clement P, Bolay F, Wapoe Y, Wiley MR, Logue J, Dighero-Kemp B, Higgs E, Gasasira A, Williams DE, Dahn B, Kateh F, Nyenswah T, Palacios G, Fallah MP.

Lancet Infect Dis. 2018 Sep;18(9):1015-1024. doi: 10.1016/S1473-3099(18)30417-1. Epub 2018 Jul 23.

PMID:
30049622
22.

Assembly of Protein Stacks With in Situ Synthesized Nanoparticle Cargo.

Manuguri S, Webster K, Yewdall NA, An Y, Venugopal H, Bhugra V, Turner A, Domigan LJ, Gerrard JA, Williams DE, Malmström J.

Nano Lett. 2018 Aug 8;18(8):5138-5145. doi: 10.1021/acs.nanolett.8b02055. Epub 2018 Jul 31.

PMID:
30047268
23.

Corrigendum to "Use of a handheld low-cost sensor to explore the effect of urban design features on local-scale spatial and temporal air quality variability" [Sci. Total Environ. 619-620 (2018) 480-490].

Miskell G, Salmond JA, Williams DE.

Sci Total Environ. 2018 Jul 1;628-629:1405. doi: 10.1016/j.scitotenv.2018.02.142. Epub 2018 Feb 28. No abstract available.

PMID:
30045560
24.

Broccoli Sprouts Delay Prostate Cancer Formation and Decrease Prostate Cancer Severity with a Concurrent Decrease in HDAC3 Protein Expression in Transgenic Adenocarcinoma of the Mouse Prostate (TRAMP) Mice.

Beaver LM, Lӧhr CV, Clarke JD, Glasser ST, Watson GW, Wong CP, Zhang Z, Williams DE, Dashwood RH, Shannon J, Thuillier P, Ho E.

Curr Dev Nutr. 2017 Dec 26;2(3):nzy002. doi: 10.1093/cdn/nzy002. eCollection 2018 Mar.

25.

Identification of Novel HIV-1 Latency-Reversing Agents from a Library of Marine Natural Products.

Richard K, Williams DE, de Silva ED, Brockman MA, Brumme ZL, Andersen RJ, Tietjen I.

Viruses. 2018 Jun 27;10(7). pii: E348. doi: 10.3390/v10070348.

26.

Association Is Not Causation.

Williams DE.

Toxicol Sci. 2018 Jul 1;164(1):3. doi: 10.1093/toxsci/kfy095. No abstract available.

PMID:
29912408
27.

Flipping the Switch: Fast Photoisomerization in a Confined Environment.

Williams DE, Martin CR, Dolgopolova EA, Swifton A, Godfrey DC, Ejegbavwo OA, Pellechia PJ, Smith MD, Shustova NB.

J Am Chem Soc. 2018 Jun 20;140(24):7611-7622. doi: 10.1021/jacs.8b02994. Epub 2018 Jun 12.

PMID:
29807417
28.

Cross-Border Transmission of Ebola Virus as the Cause of a Resurgent Outbreak in Liberia in April 2016.

Mate SE, Wiley MR, Ladner JT, Dokubo EK, Fakoli L, Fallah M, Nyenswah TG, DiClaro JW, Deboer JT, Williams DE, Bolay F, Palacios G.

Clin Infect Dis. 2018 Sep 14;67(7):1147-1149. doi: 10.1093/cid/ciy281. No abstract available.

PMID:
29659740
29.

Direct Writing and Characterization of Three-Dimensional Conducting Polymer PEDOT Arrays.

Zhang P, Aydemir N, Alkaisi M, Williams DE, Travas-Sejdic J.

ACS Appl Mater Interfaces. 2018 Apr 11;10(14):11888-11895. doi: 10.1021/acsami.8b02289. Epub 2018 Mar 30.

PMID:
29570263
30.

Phospholipid flippases and Sfk1p, a novel regulator of phospholipid asymmetry, contribute to low permeability of the plasma membrane.

Mioka T, Fujimura-Kamada K, Mizugaki N, Kishimoto T, Sano T, Nunome H, Williams DE, Andersen RJ, Tanaka K.

Mol Biol Cell. 2018 May 15;29(10):1203-1218. doi: 10.1091/mbc.E17-04-0217. Epub 2018 Mar 22.

31.

Race/Ethnicity, Dietary Acid Load, and Risk of End-Stage Renal Disease among US Adults with Chronic Kidney Disease.

Crews DC, Banerjee T, Wesson DE, Morgenstern H, Saran R, Burrows NR, Williams DE, Powe NR; Centers for Disease Control and Prevention Chronic Kidney Disease Surveillance Team.

Am J Nephrol. 2018;47(3):174-181. doi: 10.1159/000487715. Epub 2018 Mar 9.

32.

Pharmacokinetics of [14C]-Benzo[a]pyrene (BaP) in humans: Impact of Co-Administration of smoked salmon and BaP dietary restriction.

Hummel JM, Madeen EP, Siddens LK, Uesugi SL, McQuistan T, Anderson KA, Turteltaub KW, Ognibene TJ, Bench G, Krueger SK, Harris S, Smith J, Tilton SC, Baird WM, Williams DE.

Food Chem Toxicol. 2018 May;115:136-147. doi: 10.1016/j.fct.2018.03.003. Epub 2018 Mar 5.

33.

Solution to the Problem of Calibration of Low-Cost Air Quality Measurement Sensors in Networks.

Miskell G, Salmond JA, Williams DE.

ACS Sens. 2018 Apr 27;3(4):832-843. doi: 10.1021/acssensors.8b00074. Epub 2018 Mar 15.

PMID:
29508622
34.

Inhibition of NF-κB-dependent HIV-1 replication by the marine natural product bengamide A.

Tietjen I, Williams DE, Read S, Kuang XT, Mwimanzi P, Wilhelm E, Markle T, Kinloch NN, Naphen CN, Tenney K, Mesplède T, Wainberg MA, Crews P, Bell B, Andersen RJ, Brumme ZL, Brockman MA.

Antiviral Res. 2018 Apr;152:94-103. doi: 10.1016/j.antiviral.2018.02.017. Epub 2018 Feb 22.

PMID:
29476895
35.

Untargeted Metabolomic Screen Reveals Changes in Human Plasma Metabolite Profiles Following Consumption of Fresh Broccoli Sprouts.

Housley L, Magana AA, Hsu A, Beaver LM, Wong CP, Stevens JF, Choi J, Jiang Y, Bella D, Williams DE, Maier CS, Shannon J, Dashwood RH, Ho E.

Mol Nutr Food Res. 2018 Oct;62(19):e1700665. doi: 10.1002/mnfr.201700665. Epub 2018 Feb 23.

36.

Serpulanines A to C, N-Oxidized Tyrosine Derivatives Isolated from the Sri Lankan Fungus Serpula sp.: Structure Elucidation, Synthesis, and Histone Deacetylase Inhibition.

Williams DE, Gunasekara NW, Ratnaweera PB, Zheng Z, Ellis S, Dada S, Patrick BO, Wijesundera RLC, Nanayakkara CM, Jefferies WA, de Silva ED, Andersen RJ.

J Nat Prod. 2018 Jan 26;81(1):78-84. doi: 10.1021/acs.jnatprod.7b00680. Epub 2018 Jan 5.

PMID:
29303267
37.

Use of a handheld low-cost sensor to explore the effect of urban design features on local-scale spatial and temporal air quality variability.

Miskell G, Salmond JA, Williams DE.

Sci Total Environ. 2018 Apr 1;619-620:480-490. doi: 10.1016/j.scitotenv.2017.11.024. Epub 2017 Nov 29. Erratum in: Sci Total Environ. 2018 Jul 1;628-629:1405.

PMID:
29156268
38.

Development of a microscale land use regression model for predicting NO2 concentrations at a heavy trafficked suburban area in Auckland, NZ.

Weissert LF, Salmond JA, Miskell G, Alavi-Shoshtari M, Williams DE.

Sci Total Environ. 2018 Apr 1;619-620:112-119. doi: 10.1016/j.scitotenv.2017.11.028. Epub 2017 Nov 13.

PMID:
29145048
39.

Formation of supramolecular protein structures on gold surfaces.

Domigan LJ, Ashmead H, Dimartino S, Malmstrom J, Grant Pearce F, Blunt M, Williams DE, Gerrard JA.

Biointerphases. 2017 Nov 15;12(4):04E405. doi: 10.1116/1.4986053.

PMID:
29141412
40.

Rapid Laboratory Identification of Neisseria meningitidis Serogroup C as the Cause of an Outbreak - Liberia, 2017.

Patel JC, George J, Vuong J, Potts CC, Bozio C, Clark TA, Thomas J, Schier J, Chang A, Waller JL, Diaz MH, Whaley M, Jenkins LT, Fuller S, Williams DE, Redd JT, Arthur RR, Taweh F, Vera Walker Y, Hardy P, Freeman M, Katawera V, Gwesa G, Gbanya MZ, Clement P, Kohar H, Stone M, Fallah M, Nyenswah T, Winchell JM, Wang X, McNamara LA, Dokubo EK, Fox LM.

MMWR Morb Mortal Wkly Rep. 2017 Oct 27;66(42):1144-1147. doi: 10.15585/mmwr.mm6642a5. Erratum in: MMWR Morb Mortal Wkly Rep. 2017 Nov 17;66(45):1262.

41.

The Croton megalobotrys Müll Arg. traditional medicine in HIV/AIDS management: Documentation of patient use, in vitro activation of latent HIV-1 provirus, and isolation of active phorbol esters.

Tietjen I, Ngwenya BN, Fotso G, Williams DE, Simonambango S, Ngadjui BT, Andersen RJ, Brockman MA, Brumme ZL, Andrae-Marobela K.

J Ethnopharmacol. 2018 Jan 30;211:267-277. doi: 10.1016/j.jep.2017.09.038. Epub 2017 Sep 29.

PMID:
28970153
42.

Bacterial Heme-Based Sensors of Nitric Oxide.

Williams DE, Nisbett LM, Bacon B, Boon E.

Antioxid Redox Signal. 2018 Dec 20;29(18):1872-1887. doi: 10.1089/ars.2017.7235. Epub 2017 Sep 28. Review.

PMID:
28847157
43.

Chemical Transformations of the Fungal Meroterpenoid Dhilirolide A Reveal Skeletal Degradation and Rearrangement Reactions with Biosynthetic Implications.

Wong KM, Williams DE, Centko R, de Silva ED, Andersen RJ.

Org Lett. 2017 Sep 1;19(17):4488-4491. doi: 10.1021/acs.orglett.7b02037. Epub 2017 Aug 14.

PMID:
28805391
44.

Thermal stress exposure, bleaching response, and mortality in the threatened coral Acropora palmata.

Williams DE, Miller MW, Bright AJ, Pausch RE, Valdivia A.

Mar Pollut Bull. 2017 Nov 15;124(1):189-197. doi: 10.1016/j.marpolbul.2017.07.001. Epub 2017 Jul 24.

PMID:
28751030
45.

Surface engineering of poly(methylmethacrylate): Effects on fluorescence immunoassay.

Akers PW, Hoai Le NC, Nelson ARJ, McKenna M, O'Mahony C, McGillivray DJ, Gubala V, Williams DE.

Biointerphases. 2017 Jun 6;12(2):02C415. doi: 10.1116/1.4984010.

PMID:
28587470
46.

New immobilisation method for oligonucleotides on electrodes enables highly-sensitive, electrochemical label-free gene sensing.

Aydemir N, Chan E, Baek P, Barker D, Williams DE, Travas-Sejdic J.

Biosens Bioelectron. 2017 Nov 15;97:128-135. doi: 10.1016/j.bios.2017.05.049. Epub 2017 Jun 1.

PMID:
28582708
47.

The phytochemical 3,3'-diindolylmethane decreases expression of AR-controlled DNA damage repair genes through repressive chromatin modifications and is associated with DNA damage in prostate cancer cells.

Palomera-Sanchez Z, Watson GW, Wong CP, Beaver LM, Williams DE, Dashwood RH, Ho E.

J Nutr Biochem. 2017 Sep;47:113-119. doi: 10.1016/j.jnutbio.2017.05.005. Epub 2017 May 25.

48.

Associations between persistent organic pollutants, type 2 diabetes, diabetic nephropathy and mortality.

Grice BA, Nelson RG, Williams DE, Knowler WC, Mason C, Hanson RL, Bullard KM, Pavkov ME.

Occup Environ Med. 2017 Jul;74(7):521-527. doi: 10.1136/oemed-2016-103948. Epub 2017 Apr 24.

49.

A miRNA signature for an environmental heterocyclic amine defined by a multi-organ carcinogenicity bioassay in the rat.

Chen YS, Wang R, Dashwood WM, Löhr CV, Williams DE, Ho E, Mertens-Talcott S, Dashwood RH.

Arch Toxicol. 2017 Oct;91(10):3415-3425. doi: 10.1007/s00204-017-1945-6. Epub 2017 Mar 13.

50.

US immigration order strikes against biotech.

Levin JM, Holtzman SH, Maraganore J, Hastings PJ, Cohen R, Dahiyat B, Adams J, Adams C, Ahrens B, Albers J, Aspinall MG, Audia JE, Babler M, Barrett P, Barry Z, Bermingham N, Bloch S, Blum RI, Bolno PB, Bonney MW, Booth B, Bradbury DM, Brauer SK, Byers B, Cagnoni PJ, Cali BM, Ciechanover I, Clark C, Clayman MD, Cleland JL, Cobb P, Cooper R, Currie MG, Diekman J, Dobmeier EL, Doerfler D, Donley EL, Dunsire D, During M, Eckstein JW, Elenko E, Exter NA, Fleming JJ, Flesher GJ, Formela JF, Forrester R, Francois C, Franklin H, Freeman MW, Furst H, Gage LP, Galakatos N, Gallagher BM, Geraghty JA, Gill S, Goeddel DV, Goldsmith MA, Gowen M, Goyal V, Graney T, Grayzel D, Greene B, Grint P, Gutierrez-Ramos JC, Haney B, Ha-Ngoc T, Harris T, Hasnain F, Hata YS, Hecht P, Henshaw L, Heyman R, Hoppenot H, Horvitz HR, Hughes TE, Hutton WS, Isaacs ST, Jenkins A, Jonker J, Kaplan J, Karsen P, Keiper J, Kim J, Kindler J, King R, King V, Kjellson N, Koenig S, Koenig G, Kolchinsky P, Laikind P, Langer RB, Lee JJ, Leff JS, Leicher BA, Leschly N, Levin A, Levin M, Levine AJ, Levy A, Liu DR, Lodish HF, Lopatin U, Love TW, Macdonald G, Maderis GJ, Mahadevia A, Mahanthappa NK, Martin JF, Martin A, Martucci WE, McArthur JG, McCann CM, McCarthy SA, McDonough CG, Mendlein J, Miller L, Miralles D, Moch KI, More B, Myers AG, Narachi MA, Nashat A, Nelson W, Newell WJ, Olle B, Osborn JE, Owens JC, Pande A, Papadopoulos S, Parker HS, Parmar KM, Patterson MR, Paul SM, Perez R, Perry M, Pfeffer CG, Powell M, Pruzanski M, Purcell DJ, Rakhit A, Ramamoorthi K, Rastetter W, Rawcliffe AA, Reid LE, Renaud RC, Rhodes JP, Rieflin WJ, Robins C, Rocklage SM, Rosenblatt M, Rosin JG, Rutter WJ, Saha S, Samuels C, Sato VL, Scangos G, Scarlett JA, Schenkein D, Schreiber SL, Schwab A, Sekhri P, Shah R, Shenk T, Siegall CB, Simon NJ, Simonian N, Stein J, Su M, Szela MT, Taglietti M, Tandon N, Termeer H, Thornberry NA, Tolar M, Ulevitch R, Vaishnaw AK, VanLent A, Varsavsky M, Vlasuk GP, Vounatsos M, Waksal SG, Warma N, Watts RJ, Werber Y, Westphal C, Wierenga W, Williams DE, Williams LR, Xanthopoulos KG, Zohar D, Zweifach SS.

Nat Biotechnol. 2017 Mar 7;35(3):204-206. doi: 10.1038/nbt.3824. No abstract available.

PMID:
28267733

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