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Factors Affecting Combination Trial Success (FACTS): Investigator Survey Results on Early-Phase Combination Trials.

Paller CJ, Huang EP, Luechtefeld T, Massett HA, Williams CC, Zhao J, Gravell AE, Tamashiro T, Reeves SA, Rosner GL, Carducci MA, Rubinstein L, Ivy SP.

Front Med (Lausanne). 2019 Jun 4;6:122. doi: 10.3389/fmed.2019.00122. eCollection 2019.


Adapting stigma mechanism frameworks to explore complex pathways between intersectional stigma and HIV-related health outcomes among women living with HIV in Canada.

Logie CH, Williams CC, Wang Y, Marcus N, Kazemi M, Cioppa L, Kaida A, Webster K, Beaver K, de Pokomandy A, Loutfy M.

Soc Sci Med. 2019 Jul;232:129-138. doi: 10.1016/j.socscimed.2019.04.044. Epub 2019 May 2. No abstract available.


Passively learned spatial navigation cues evoke reinforcement learning reward signals.

Ferguson TD, Williams CC, Skelton RW, Krigolson OE.

Cognition. 2019 Aug;189:65-75. doi: 10.1016/j.cognition.2019.03.015. Epub 2019 Mar 28.


A 30 kDa polyethylene glycol-enfuvirtide complex enhances the exposure of enfuvirtide in lymphatic viral reservoirs in rats.

Kaminskas LM, Williams CC, Leong NJ, Chan LJ, Butcher NJ, Feeney OM, Porter CJH, Tyssen D, Tachedjian G, Ascher DB.

Eur J Pharm Biopharm. 2019 Apr;137:218-226. doi: 10.1016/j.ejpb.2019.03.008. Epub 2019 Mar 6.


Thinking theta and alpha: Mechanisms of intuitive and analytical reasoning.

Williams CC, Kappen M, Hassall CD, Wright B, Krigolson OE.

Neuroimage. 2019 Apr 1;189:574-580. doi: 10.1016/j.neuroimage.2019.01.048. Epub 2019 Jan 22.


Randomized-controlled phase II trial of salvage chemotherapy after immunization with a TP53-transfected dendritic cell-based vaccine (Ad.p53-DC) in patients with recurrent small cell lung cancer.

Chiappori AA, Williams CC, Gray JE, Tanvetyanon T, Haura EB, Creelan BC, Thapa R, Chen DT, Simon GR, Bepler G, Gabrilovich DI, Antonia SJ.

Cancer Immunol Immunother. 2019 Mar;68(3):517-527. doi: 10.1007/s00262-018-2287-9. Epub 2018 Dec 27.


NCCN Guidelines Insights: Small Cell Lung Cancer, Version 2.2018.

Kalemkerian GP, Loo BW, Akerley W, Attia A, Bassetti M, Boumber Y, Decker R, Dobelbower MC, Dowlati A, Downey RJ, Florsheim C, Ganti AKP, Grecula JC, Gubens MA, Hann CL, Hayman JA, Heist RS, Koczywas M, Merritt RE, Mohindra N, Molina J, Moran CA, Morgensztern D, Pokharel S, Portnoy DC, Rhodes D, Rusthoven C, Santana-Davila R, Williams CC, Hoffmann KG, Hughes M.

J Natl Compr Canc Netw. 2018 Oct;16(10):1171-1182. doi: 10.6004/jnccn.2018.0079.


A phase I/randomized phase II study of GM.CD40L vaccine in combination with CCL21 in patients with advanced lung adenocarcinoma.

Gray JE, Chiappori A, Williams CC, Tanvetyanon T, Haura EB, Creelan BC, Kim J, Boyle TA, Pinder-Schenck M, Khalil F, Altiok S, Devane R, Noyes D, Mediavilla-Varela M, Smilee R, Hopewell EL, Kelley L, Antonia SJ.

Cancer Immunol Immunother. 2018 Dec;67(12):1853-1862. doi: 10.1007/s00262-018-2236-7. Epub 2018 Sep 12.


Impact of military type footwear and load carrying workload on postural stability.

Chander H, Knight AC, Garner JC, Wade C, Carruth D, Wilson SJ, Gdovin JR, Williams CC.

Ergonomics. 2019 Jan;62(1):103-114. doi: 10.1080/00140139.2018.1521528. Epub 2018 Nov 15.


Chasing the zone: Reduced beta power predicts baseball batting performance.

Pluta A, Williams CC, Binsted G, Hecker KG, Krigolson OE.

Neurosci Lett. 2018 Nov 1;686:150-154. doi: 10.1016/j.neulet.2018.09.004. Epub 2018 Sep 6.


In spite of the system: A qualitatively-driven mixed methods analysis of the mental health services experiences of LGBTQ people living in poverty in Ontario, Canada.

Ross LE, Gibson MF, Daley A, Steele LS, Williams CC.

PLoS One. 2018 Aug 15;13(8):e0201437. doi: 10.1371/journal.pone.0201437. eCollection 2018.


Alcohol hangover impacts learning and reward processing within the medial-frontal cortex.

Howse AD, Hassall CD, Williams CC, Hajcak G, Krigolson OE.

Psychophysiology. 2018 Aug;55(8):e13081. doi: 10.1111/psyp.13081. Epub 2018 Mar 30.


Synthesis, Characterization, and Computational Modeling of N-(1-Ethoxyvinyl)pyridinium Triflates, an Unusual Class of Pyridinium Salts.

Shapiro JD, Sonberg JC, Schafer BC, Williams CC, Ferris HR, Reinheimer EW, Van Wynsberghe AW, Kriley CE, Majireck MM.

Molecules. 2018 Feb 14;23(2). pii: E413. doi: 10.3390/molecules23020413.


Patient, caregiver and physician perspectives on participating in a thoracic rapid tissue donation program.

Quinn GP, Pentz RD, Muñoz-Antonia T, Boyle TA, Schabath MB, Pratt CL, Shaffer A, Duarte LF, Bowman-Curci M, Antonia SJ, Chiappori AA, Creelan BC, Gray JE, Williams CC, Haura EB.

Patient Educ Couns. 2018 Apr;101(4):703-710. doi: 10.1016/j.pec.2017.11.014. Epub 2017 Nov 28.


Surfactant protein-A nanobody-conjugated liposomes loaded with methylprednisolone increase lung-targeting specificity and therapeutic effect for acute lung injury.

Li N, Weng D, Wang SM, Zhang Y, Chen SS, Yin ZF, Zhai J, Scoble J, Williams CC, Chen T, Qiu H, Wu Q, Zhao MM, Lu LQ, Mulet X, Li HP.

Drug Deliv. 2017 Nov;24(1):1770-1781. doi: 10.1080/10717544.2017.1402217.


Sugar analog synthesis by in vitro biocatalytic cascade: A comparison of alternative enzyme complements for dihydroxyacetone phosphate production as a precursor to rare chiral sugar synthesis.

Hartley CJ, French NG, Scoble JA, Williams CC, Churches QI, Frazer AR, Taylor MC, Coia G, Simpson G, Turner NJ, Scott C.

PLoS One. 2017 Nov 7;12(11):e0184183. doi: 10.1371/journal.pone.0184183. eCollection 2017.


The application of reward learning in the real world: Changes in the reward positivity amplitude reflect learning in a medical education context.

Williams CC, Hecker KG, Paget MK, Coderre SP, Burak KW, Wright B, Krigolson OE.

Int J Psychophysiol. 2018 Oct;132(Pt B):236-242. doi: 10.1016/j.ijpsycho.2017.10.010. Epub 2017 Oct 27.


The Influence of an Acute Bout of Whole Body Vibration on Human Postural Control Responses.

Wilson SJ, Williams CC, Gdovin JR, Eason JD 2nd, Luginsland LA, Hill CM, Chander H, Wade C, Garner JC.

J Mot Behav. 2018 Sep-Oct;50(5):590-597. doi: 10.1080/00222895.2017.1383225. Epub 2017 Oct 23.


The Effects of Various Weighted Implements on Baseball Swing Kinematics in Collegiate Baseball Players.

Williams CC, Gdovin JR, Wilson SJ, Cazas-Moreno VL, Eason JD, Hoke EL, Allen CR, Wade C, Garner JC.

J Strength Cond Res. 2019 May;33(5):1347-1353. doi: 10.1519/JSC.0000000000002020.


When theory and biology differ: The relationship between reward prediction errors and expectancy.

Williams CC, Hassall CD, Trska R, Holroyd CB, Krigolson OE.

Biol Psychol. 2017 Oct;129:265-272. doi: 10.1016/j.biopsycho.2017.09.007. Epub 2017 Sep 18.


Safety, pharmacokinetics, and pharmacodynamics of oral omaveloxolone (RTA 408), a synthetic triterpenoid, in a first-in-human trial of patients with advanced solid tumors.

Creelan BC, Gabrilovich DI, Gray JE, Williams CC, Tanvetyanon T, Haura EB, Weber JS, Gibney GT, Markowitz J, Proksch JW, Reisman SA, McKee MD, Chin MP, Meyer CJ, Antonia SJ.

Onco Targets Ther. 2017 Aug 29;10:4239-4250. doi: 10.2147/OTT.S136992. eCollection 2017.


Rethinking informal payments by patients in Europe: An institutional approach.

Williams CC, Horodnic AV.

Health Policy. 2017 Oct;121(10):1053-1062. doi: 10.1016/j.healthpol.2017.08.007. Epub 2017 Aug 30.


Effects of Jaw Clenching and Jaw Alignment Mouthpiece Use on Force Production During Vertical Jump and Isometric Clean Pull.

Allen CR, Fu YC, Cazas-Moreno V, Valliant MW, Gdovin JR, Williams CC, Garner JC.

J Strength Cond Res. 2018 Jan;32(1):237-243. doi: 10.1519/JSC.0000000000002172.


An Evaluation of Optimal PEGylation Strategies for Maximizing the Lymphatic Exposure and Antiviral Activity of Interferon after Subcutaneous Administration.

Chan LJ, Feeney OM, Leong NJ, McLeod VM, Porter CJH, Williams CC, Kaminskas LM.

Biomacromolecules. 2017 Sep 11;18(9):2866-2875. doi: 10.1021/acs.biomac.7b00794. Epub 2017 Aug 11.


Task-relevant perceptual features can define categories in visual memory too.

Antonelli KB, Williams CC.

Mem Cognit. 2017 Nov;45(8):1295-1305. doi: 10.3758/s13421-017-0728-x.


The Role of the Amygdala in Value-Based Learning.

Hassall CD, Williams CC.

J Neurosci. 2017 Jul 12;37(28):6601-6602. doi: 10.1523/JNEUROSCI.1073-17.2017. No abstract available.


Work zone sign design for increased driver compliance and worker safety.

Rahman MM, Strawderman L, Garrison T, Eakin D, Williams CC.

Accid Anal Prev. 2017 Sep;106:67-75. doi: 10.1016/j.aap.2017.05.023. Epub 2017 Jun 3.


Choosing MUSE: Validation of a Low-Cost, Portable EEG System for ERP Research.

Krigolson OE, Williams CC, Norton A, Hassall CD, Colino FL.

Front Neurosci. 2017 Mar 10;11:109. doi: 10.3389/fnins.2017.00109. eCollection 2017.


The case of the missing visual details: Occlusion and long-term visual memory.

Williams CC, Burkle KA.

J Exp Psychol Learn Mem Cogn. 2017 Oct;43(10):1567-1580. doi: 10.1037/xlm0000393. Epub 2017 Mar 2.


Depression and discrimination in the lives of women, transgender and gender liminal people in Ontario, Canada.

Williams CC, Curling D, Steele LS, Gibson MF, Daley A, Green DC, Ross LE.

Health Soc Care Community. 2017 May;25(3):1139-1150. doi: 10.1111/hsc.12414. Epub 2017 Jan 18.


LGBT Identity, Untreated Depression, and Unmet Need for Mental Health Services by Sexual Minority Women and Trans-Identified People.

Steele LS, Daley A, Curling D, Gibson MF, Green DC, Williams CC, Ross LE.

J Womens Health (Larchmt). 2017 Feb;26(2):116-127. doi: 10.1089/jwh.2015.5677. Epub 2016 Nov 29.


Salmonella Typhimurium Enzymatically Landscapes the Host Intestinal Epithelial Cell (IEC) Surface Glycome to Increase Invasion.

Park D, Arabyan N, Williams CC, Song T, Mitra A, Weimer BC, Maverakis E, Lebrilla CB.

Mol Cell Proteomics. 2016 Dec;15(12):3653-3664. Epub 2016 Oct 17.


A chemiluminescent sandwich ELISA enhancement method using a chromium (III) coordination complex.

Welch NG, Easton CD, Scoble JA, Williams CC, Pigram PJ, Muir BW.

J Immunol Methods. 2016 Nov;438:59-66. doi: 10.1016/j.jim.2016.09.003. Epub 2016 Sep 17.


High-Throughput Production of Chromium(III) Complexes for Antibody Immobilization.

Welch NG, Scoble JA, Easton CD, Williams CC, Bradford BJ, Mamedova LK, Pigram PJ, Muir BW.

Anal Chem. 2016 Oct 18;88(20):10102-10110. doi: 10.1021/acs.analchem.6b02531. Epub 2016 Oct 5.


Salmonella Degrades the Host Glycocalyx Leading to Altered Infection and Glycan Remodeling.

Arabyan N, Park D, Foutouhi S, Weis AM, Huang BC, Williams CC, Desai P, Shah J, Jeannotte R, Kong N, Lebrilla CB, Weimer BC.

Sci Rep. 2016 Jul 8;6:29525. doi: 10.1038/srep29525.


The scarcity heuristic impacts reward processing within the medial-frontal cortex.

Williams CC, Saffer BY, McCulloch RB, Krigolson OE.

Neuroreport. 2016 May 4;27(7):522-6. doi: 10.1097/WNR.0000000000000575.


Conjugation of 10 kDa Linear PEG onto Trastuzumab Fab' Is Sufficient to Significantly Enhance Lymphatic Exposure while Preserving in Vitro Biological Activity.

Chan LJ, Ascher DB, Yadav R, Bulitta JB, Williams CC, Porter CJ, Landersdorfer CB, Kaminskas LM.

Mol Pharm. 2016 Apr 4;13(4):1229-41. doi: 10.1021/acs.molpharmaceut.5b00749. Epub 2016 Feb 29.


Electrical current through individual pairs of phosphorus donor atoms and silicon dangling bonds.

Ambal K, Rahe P, Payne A, Slinkman J, Williams CC, Boehme C.

Sci Rep. 2016 Jan 13;6:18531. doi: 10.1038/srep18531.


Consecutive Charging of a Molecule-on-Insulator Ensemble Using Single Electron Tunnelling Methods.

Rahe P, Steele RP, Williams CC.

Nano Lett. 2016 Feb 10;16(2):911-6. doi: 10.1021/acs.nanolett.5b03725. Epub 2016 Jan 7.


Glyceollin I Reverses Epithelial to Mesenchymal Transition in Letrozole Resistant Breast Cancer through ZEB1.

Carriere PP, Llopis SD, Naiki AC, Nguyen G, Phan T, Nguyen MM, Preyan LC, Yearby L, Pratt J, Burks H, Davenport IR, Nguyen TA, Parker-Lemieux K, Payton-Stewart F, Williams CC, Boué SM, Burow ME, Collins-Burow B, Hilliard A, Davidson AM, Tilghman SL.

Int J Environ Res Public Health. 2015 Dec 22;13(1):ijerph13010010. doi: 10.3390/ijerph13010010.


Dynamic tunneling force microscopy for characterizing electronic trap states in non-conductive surfaces.

Wang R, Williams CC.

Rev Sci Instrum. 2015 Sep;86(9):093708. doi: 10.1063/1.4931065.


Short communication: Substituting dry distillers grains with solubles and rumen-protected amino acids for soybean meal in late-lactation cows' diets based on corn silage or ryegrass silage.

Pereira AB, Zeringue LK, Leonardi C, Jenny BF, Williams CC, McCormick ME, Moreira VR.

J Dairy Sci. 2015 Nov;98(11):8121-7. doi: 10.3168/jds.2015-9604. Epub 2015 Sep 9.


LOCAL TRANSLATION. Response to Comment on "Principles of ER cotranslational translocation revealed by proximity-specific ribosome profiling".

Jan CH, Williams CC, Weissman JS.

Science. 2015 Jun 12;348(6240):1217. doi: 10.1126/science.aaa8299. Epub 2015 Jun 11.


The Serum Immunoglobulin G Glycosylation Signature of Gastric Cancer.

Ruhaak LR, Barkauskas DA, Torres J, Cooke CL, Wu LD, Stroble C, Ozcan S, Williams CC, Camorlinga M, Rocke DM, Lebrilla CB, Solnick JV.

EuPA Open Proteom. 2015 Mar 1;6:1-9.


PEGylation does not significantly change the initial intravenous or subcutaneous pharmacokinetics or lymphatic exposure of trastuzumab in rats but increases plasma clearance after subcutaneous administration.

Chan LJ, Bulitta JB, Ascher DB, Haynes JM, McLeod VM, Porter CJ, Williams CC, Kaminskas LM.

Mol Pharm. 2015 Mar 2;12(3):794-809. doi: 10.1021/mp5006189. Epub 2015 Feb 18.


Clinical outcomes of patients with advanced gastrointestinal stromal tumors: safety and efficacy in a worldwide treatment-use trial of sunitinib.

Reichardt P, Kang YK, Rutkowski P, Schuette J, Rosen LS, Seddon B, Yalcin S, Gelderblom H, Williams CC Jr, Fumagalli E, Biasco G, Hurwitz HI, Kaiser PE, Fly K, Matczak E, Chen L, Lechuga MJ, Demetri GD.

Cancer. 2015 May 1;121(9):1405-13. doi: 10.1002/cncr.29220. Epub 2015 Jan 13. Erratum in: Cancer. 2019 Mar 1;125(5):821.


Pilot study of methods and equipment for in-home noise level measurements.

Neitzel RL, Heikkinen MS, Williams CC, Viet SM, Dellarco M.

Appl Acoust. 2015 Jan 15;102:1-11.


Characterization of tweety gene (ttyh1-3) expression in Xenopus laevis during embryonic development.

Halleran AD, Sehdev M, Rabe BA, Huyck RW, Williams CC, Saha MS.

Gene Expr Patterns. 2015 Jan;17(1):38-44. doi: 10.1016/j.gep.2014.12.002. Epub 2014 Dec 23.


Principles of ER cotranslational translocation revealed by proximity-specific ribosome profiling.

Jan CH, Williams CC, Weissman JS.

Science. 2014 Nov 7;346(6210):1257521. doi: 10.1126/science.1257521. Epub 2014 Nov 6.


Targeting and plasticity of mitochondrial proteins revealed by proximity-specific ribosome profiling.

Williams CC, Jan CH, Weissman JS.

Science. 2014 Nov 7;346(6210):748-51. doi: 10.1126/science.1257522.

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