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Emerging antimicrobial resistance among Escherichia coli strains in bloodstream infections in Toronto, 2006-2016: a retrospective cohort study.

Mineau S, Kozak R, Kissoon M, Paterson A, Oppedisano A, Douri F, Gogan K, Willey BM, McGeer A, Poutanen SM.

CMAJ Open. 2018 Dec 3;6(4):E580-E586. doi: 10.9778/cmajo.20180039. Print 2018 Oct-Dec.


Prevalence of vancomycin-variable Enterococcus faecium (VVE) among vanA-positive sterile site isolates and patient factors associated with VVE bacteremia.

Kohler P, Eshaghi A, Kim HC, Plevneshi A, Green K, Willey BM, McGeer A, Patel SN; Toronto Invasive Bacterial Diseases Network (TIBDN).

PLoS One. 2018 Mar 22;13(3):e0193926. doi: 10.1371/journal.pone.0193926. eCollection 2018.


Enterobacter cloacae Complex Isolates Harboring blaNMC-A or blaIMI-Type Class A Carbapenemase Genes on Novel Chromosomal Integrative Elements and Plasmids.

Boyd DA, Mataseje LF, Davidson R, Delport JA, Fuller J, Hoang L, Lefebvre B, Levett PN, Roscoe DL, Willey BM, Mulvey MR.

Antimicrob Agents Chemother. 2017 Apr 24;61(5). pii: e02578-16. doi: 10.1128/AAC.02578-16. Print 2017 May.


Community- and Healthcare-Associated Methicillin-Resistant Staphylococcus aureus Strains: An Investigation Into Household Transmission, Risk Factors, and Environmental Contamination.

Ng W, Faheem A, McGeer A, Simor AE, Gelosia A, Willey BM, Watt C, Richardson DC, Wong H, Ostrowska K, Vernich L, Muller MP, Gnanasuntharam P, Porter V, Katz K.

Infect Control Hosp Epidemiol. 2017 Jan;38(1):61-67. doi: 10.1017/ice.2016.245. Epub 2016 Nov 8.


New Delhi metallo-β-lactamase in Jamaica.

Thoms-Rodriguez CA, Mazzulli T, Christian N, Willey BM, Boyd DA, Mataseje LF, Mulvey MR, Christie CD, Nicholson AM.

J Infect Dev Ctries. 2016 Feb 28;10(2):183-7. doi: 10.3855/jidc.7094.


Serratia marcescens harbouring SME-type class A carbapenemases in Canada and the presence of blaSME on a novel genomic island, SmarGI1-1.

Mataseje LF, Boyd DA, Delport J, Hoang L, Imperial M, Lefebvre B, Kuhn M, Van Caeseele P, Willey BM, Mulvey MR.

J Antimicrob Chemother. 2014 Jul;69(7):1825-9. doi: 10.1093/jac/dku040. Epub 2014 Mar 21.


Vancomycin-variable Enterococcus faecium: in vivo emergence of vancomycin resistance in a vancomycin-susceptible isolate.

Coburn B, Low DE, Patel SN, Poutanen SM, Shahinas D, Eshaghi A, Willey BM, McGeer A.

J Clin Microbiol. 2014 May;52(5):1766-7. doi: 10.1128/JCM.03579-13. Epub 2014 Feb 12.


Carbapenem-hydrolyzing oxacillinase-48 and oxacillinase-181 in Canada, 2011.

Mataseje LF, Boyd DA, Hoang L, Imperial M, Lefebvre B, Miller M, Poutanen SM, Roscoe D, Willey BM, Mulvey MR.

Emerg Infect Dis. 2013 Jan;19(1):157-60. doi: 10.3201/eid1901.120706. No abstract available.


Prevalence and predictors of MRSA, ESBL, and VRE colonization in the ambulatory IBD population.

Leung W, Malhi G, Willey BM, McGeer AJ, Borgundvaag B, Thanabalan R, Gnanasuntharam P, Le B, Weizman AV, Croitoru K, Silverberg MS, Steinhart AH, Nguyen GC.

J Crohns Colitis. 2012 Aug;6(7):743-9. doi: 10.1016/j.crohns.2011.12.005. Epub 2012 Jan 9.


Group A Streptococcus emm gene types in pharyngeal isolates, Ontario, Canada, 2002-2010.

Shea PR, Ewbank AL, Gonzalez-Lugo JH, Martagon-Rosado AJ, Martinez-Gutierrez JC, Rehman HA, Serrano-Gonzalez M, Fittipaldi N, Beres SB, Flores AR, Low DE, Willey BM, Musser JM.

Emerg Infect Dis. 2011 Nov;17(11):2010-7. doi: 10.3201/eid1711.110159.


New Delhi metallo-β-lactamase-1: local acquisition in Ontario, Canada, and challenges in detection.

Kus JV, Tadros M, Simor A, Low DE, McGeer AJ, Willey BM, Larocque C, Pike K, Edwards IA, Dedier H, Melano R, Boyd DA, Mulvey MR, Louie L, Okeahialam C, Bayley M, Whitehead C, Richardson D, Carr L, Jinnah F, Poutanen SM.

CMAJ. 2011 Aug 9;183(11):1257-61. doi: 10.1503/cmaj.110477. Epub 2011 May 30.


Plasmid comparison and molecular analysis of Klebsiella pneumoniae harbouring bla(KPC) from New York City and Toronto.

Mataseje LF, Boyd DA, Willey BM, Prayitno N, Kreiswirth N, Gelosia A, Poutanen SM, Low DE, Jenkins SG, Katz K, Mulvey MR.

J Antimicrob Chemother. 2011 Jun;66(6):1273-7. doi: 10.1093/jac/dkr092. Epub 2011 Mar 15.


Distinct signatures of diversifying selection revealed by genome analysis of respiratory tract and invasive bacterial populations.

Shea PR, Beres SB, Flores AR, Ewbank AL, Gonzalez-Lugo JH, Martagon-Rosado AJ, Martinez-Gutierrez JC, Rehman HA, Serrano-Gonzalez M, Fittipaldi N, Ayers SD, Webb P, Willey BM, Low DE, Musser JM.

Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):5039-44. doi: 10.1073/pnas.1016282108. Epub 2011 Mar 7.


Development of a molecular-beacon-based multi-allelic real-time RT-PCR assay for the detection of human coronavirus causing severe acute respiratory syndrome (SARS-CoV): a general methodology for detecting rapidly mutating viruses.

Hadjinicolaou AV, Farcas GA, Demetriou VL, Mazzulli T, Poutanen SM, Willey BM, Low DE, Butany J, Asa SL, Kain KC, Kostrikis LG.

Arch Virol. 2011 Apr;156(4):671-80. doi: 10.1007/s00705-010-0906-7. Epub 2011 Jan 11.


Towards the photonic nose: a novel platform for molecule and bacteria identification.

Bonifacio LD, Puzzo DP, Breslav S, Willey BM, McGeer A, Ozin GA.

Adv Mater. 2010 Mar 26;22(12):1351-4. doi: 10.1002/adma.200902763. No abstract available.


Molecular complexity of successive bacterial epidemics deconvoluted by comparative pathogenomics.

Beres SB, Carroll RK, Shea PR, Sitkiewicz I, Martinez-Gutierrez JC, Low DE, McGeer A, Willey BM, Green K, Tyrrell GJ, Goldman TD, Feldgarden M, Birren BW, Fofanov Y, Boos J, Wheaton WD, Honisch C, Musser JM.

Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4371-6. doi: 10.1073/pnas.0911295107. Epub 2010 Feb 8.


Multiplex real-time PCR for rapid Staphylococcal cassette chromosome mec typing.

Chen L, Mediavilla JR, Oliveira DC, Willey BM, de Lencastre H, Kreiswirth BN.

J Clin Microbiol. 2009 Nov;47(11):3692-706. doi: 10.1128/JCM.00766-09. Epub 2009 Sep 2.


Colonization and subsequent skin and soft tissue infection due to methicillin-resistant Staphylococcus aureus in a cohort of otherwise healthy adults infected with HIV type 1.

Shet A, Mathema B, Mediavilla JR, Kishii K, Mehandru S, Jeane-Pierre P, Laroche M, Willey BM, Kreiswirth N, Markowitz M, Kreiswirth BN.

J Infect Dis. 2009 Jul 1;200(1):88-93. doi: 10.1086/599315.


A nosocomial outbreak of community-associated methicillin-resistant Staphylococcus aureus among healthy newborns and postpartum mothers.

Saunders A, Panaro L, McGeer A, Rosenthal A, White D, Willey BM, Gravel D, Bontovics E, Yaffe B, Katz K.

Can J Infect Dis Med Microbiol. 2007 Mar;18(2):128-32.


Group A streptococcal carriage among residents of an urban homeless shelter.

Bargh GJ, Hoch JS, Hwang SW, Speechley M, Willey BM, McGeer A.

Can J Infect Dis Med Microbiol. 2007 Sep;18(5):316-7. No abstract available.


Antimalarial therapy selection for quinolone resistance among Escherichia coli in the absence of quinolone exposure, in tropical South America.

Davidson RJ, Davis I, Willey BM, Rizg K, Bolotin S, Porter V, Polsky J, Daneman N, McGeer A, Yang P, Scolnik D, Rowsell R, Imas O, Silverman MS.

PLoS One. 2008 Jul 16;3(7):e2727. doi: 10.1371/journal.pone.0002727.


Molecular characterization of Enterococcus faecalis N06-0364 with low-level vancomycin resistance harboring a novel D-Ala-D-Ser gene cluster, vanL.

Boyd DA, Willey BM, Fawcett D, Gillani N, Mulvey MR.

Antimicrob Agents Chemother. 2008 Jul;52(7):2667-72. doi: 10.1128/AAC.01516-07. Epub 2008 May 5.


Interferon-mediated immunopathological events are associated with atypical innate and adaptive immune responses in patients with severe acute respiratory syndrome.

Cameron MJ, Ran L, Xu L, Danesh A, Bermejo-Martin JF, Cameron CM, Muller MP, Gold WL, Richardson SE, Poutanen SM, Willey BM, DeVries ME, Fang Y, Seneviratne C, Bosinger SE, Persad D, Wilkinson P, Greller LD, Somogyi R, Humar A, Keshavjee S, Louie M, Loeb MB, Brunton J, McGeer AJ; Canadian SARS Research Network, Kelvin DJ.

J Virol. 2007 Aug;81(16):8692-706. Epub 2007 May 30.


Methicillin-resistant Staphylococcus aureus colonization in veterinary personnel.

Hanselman BA, Kruth SA, Rousseau J, Low DE, Willey BM, McGeer A, Weese JS.

Emerg Infect Dis. 2006 Dec;12(12):1933-8.


Verification of the IDI-MRSA assay for detecting methicillin-resistant Staphylococcus aureus in diverse specimen types in a core clinical laboratory setting.

Drews SJ, Willey BM, Kreiswirth N, Wang M, Ianes T, Mitchell J, Latchford M, McGeer AJ, Katz KC.

J Clin Microbiol. 2006 Oct;44(10):3794-6.


Detection of severe acute respiratory syndrome coronavirus in stool specimens by commercially available real-time reverse transcriptase PCR assays.

Louie L, Simor AE, Chong S, Luinstra K, Petrich A, Mahony J, Smieja M, Johnson G, Gharabaghi F, Tellier R, Willey BM, Poutanen S, Mazzulli T, Broukhanski G, Jamieson F, Louie M, Richardson S; Ontario Laboratory Working Group for the Rapid Diagnosis of Emerging Pathogens.

J Clin Microbiol. 2006 Nov;44(11):4193-6. Epub 2006 Aug 30.


Severe acute respiratory syndrome diagnostics using a coronavirus protein microarray.

Zhu H, Hu S, Jona G, Zhu X, Kreiswirth N, Willey BM, Mazzulli T, Liu G, Song Q, Chen P, Cameron M, Tyler A, Wang J, Wen J, Chen W, Compton S, Snyder M.

Proc Natl Acad Sci U S A. 2006 Mar 14;103(11):4011-6. Epub 2006 Mar 7.


Methicillin-resistant Staphylococcus aureus in horses at a veterinary teaching hospital: frequency, characterization, and association with clinical disease.

Weese JS, Rousseau J, Willey BM, Archambault M, McGeer A, Low DE.

J Vet Intern Med. 2006 Jan-Feb;20(1):182-6.


Suspected transmission of methicillin-resistant Staphylococcus aureus between domestic pets and humans in veterinary clinics and in the household.

Weese JS, Dick H, Willey BM, McGeer A, Kreiswirth BN, Innis B, Low DE.

Vet Microbiol. 2006 Jun 15;115(1-3):148-55. Epub 2006 Feb 7.


An outbreak of methicillin-resistant Staphylococcus aureus skin infections resulting from horse to human transmission in a veterinary hospital.

Weese JS, Caldwell F, Willey BM, Kreiswirth BN, McGeer A, Rousseau J, Low DE.

Vet Microbiol. 2006 Apr 16;114(1-2):160-4. Epub 2005 Dec 27.


Use of a selective enrichment broth to recover Clostridium difficile from stool swabs stored under different conditions.

Arroyo LG, Rousseau J, Willey BM, Low DE, Staempfli H, McGeer A, Weese JS.

J Clin Microbiol. 2005 Oct;43(10):5341-3.


Identification of a progenitor of the CTX-M-9 group of extended-spectrum beta-lactamases from Kluyvera georgiana isolated in Guyana.

Olson AB, Silverman M, Boyd DA, McGeer A, Willey BM, Pong-Porter V, Daneman N, Mulvey MR.

Antimicrob Agents Chemother. 2005 May;49(5):2112-5.


Methicillin-resistant Staphylococcus aureus in horses and horse personnel, 2000-2002.

Weese JS, Archambault M, Willey BM, Hearn P, Kreiswirth BN, Said-Salim B, McGeer A, Likhoshvay Y, Prescott JF, Low DE.

Emerg Infect Dis. 2005 Mar;11(3):430-5.


Community-associated methicillin-resistant Staphylococcus aureus in horses and humans who work with horses.

Weese JS, Rousseau J, Traub-Dargatz JL, Willey BM, McGeer AJ, Low DE.

J Am Vet Med Assoc. 2005 Feb 15;226(4):580-3.


PCR ribotyping of Clostridium difficile isolates originating from human and animal sources.

Arroyo LG, Kruth SA, Willey BM, Staempfli HR, Low DE, Weese JS.

J Med Microbiol. 2005 Feb;54(Pt 2):163-6.


Fatal severe acute respiratory syndrome is associated with multiorgan involvement by coronavirus.

Farcas GA, Poutanen SM, Mazzulli T, Willey BM, Butany J, Asa SL, Faure P, Akhavan P, Low DE, Kain KC.

J Infect Dis. 2005 Jan 15;191(2):193-7. Epub 2004 Dec 10.


Complete nucleotide sequence of a 92-kilobase plasmid harboring the CTX-M-15 extended-spectrum beta-lactamase involved in an outbreak in long-term-care facilities in Toronto, Canada.

Boyd DA, Tyler S, Christianson S, McGeer A, Muller MP, Willey BM, Bryce E, Gardam M, Nordmann P, Mulvey MR.

Antimicrob Agents Chemother. 2004 Oct;48(10):3758-64.


Use of the Vitek-1 and Vitek-2 systems for detection of constitutive and inducible macrolide resistance in group B streptococci.

Tang P, Ng P, Lum M, Skulnick M, Small GW, Low DE, Sarabia A, Mazzulli T, Wong K, Simor AE, Willey BM.

J Clin Microbiol. 2004 May;42(5):2282-4.


Severe acute respiratory syndrome-associated coronavirus in lung tissue.

Mazzulli T, Farcas GA, Poutanen SM, Willey BM, Low DE, Butany J, Asa SL, Kain KC.

Emerg Infect Dis. 2004 Jan;10(1):20-4.


Investigation of Staphylococcus aureus isolates identified as erythromycin intermediate by the Vitek-1 System: comparison with results obtained with the Vitek-2 and Phoenix systems.

Tang P, Low DE, Atkinson S, Pike K, Ashi-Sulaiman A, Simor A, Richardson S, Willey BM.

J Clin Microbiol. 2003 Oct;41(10):4823-5.


Emergence of levofloxacin-resistant pneumococci in immunocompromised adults after therapy for community-acquired pneumonia.

Anderson KB, Tan JS, File TM Jr, DiPersio JR, Willey BM, Low DE.

Clin Infect Dis. 2003 Aug 1;37(3):376-81. Epub 2003 Jul 14.


Emergence of macrolide resistance in throat culture isolates of group a streptococci in Ontario, Canada, in 2001.

Katz KC, McGeer AJ, Duncan CL, Ashi-Sulaiman A, Willey BM, Sarabia A, McCann J, Pong-Porter S, Rzayev Y, de Azavedo JS, Low DE.

Antimicrob Agents Chemother. 2003 Jul;47(7):2370-2.


Activity of GAR-936 and other antimicrobial agents against North American isolates of Staphylococcus aureus.

Low DE, Kreiswirth BN, Weiss K, Willey BM.

Int J Antimicrob Agents. 2002 Sep;20(3):220-2.


Outbreaks of multi-drug resistant Escherichia coli in long-term care facilities in the Durham, York and Toronto regions of Ontario, 2000-2002.

Muller M, McGeer A, Willey BM, Reynolds D, Malanczyj R, Silverman M, Green MA, Culf M.

Can Commun Dis Rep. 2002 Jul 15;28(14):113-8. English, French. No abstract available.


Activity of BMS-284756, a novel des-fluoro(6) quinolone, against Staphylococcus aureus, including contributions of mutations to quinolone resistance.

Low DE, Muller M, Duncan CL, Willey BM, de Azavedo JC, McGeer A, Kreiswirth BN, Pong-Porter S, Bast DJ.

Antimicrob Agents Chemother. 2002 Apr;46(4):1119-21.


Molecular mechanisms of cefoxitin resistance in Escherichia coli from the Toronto area hospitals.

Forward KR, Willey BM, Low DE, McGeer A, Kapala MA, Kapala MM, Burrows LL.

Diagn Microbiol Infect Dis. 2001 Sep-Oct;41(1-2):57-63.


Streptococcal meningitis resulting from contact with an infected horse.

Downar J, Willey BM, Sutherland JW, Mathew K, Low DE.

J Clin Microbiol. 2001 Jun;39(6):2358-9.


Practical approach to the identification of clinically relevant Enterococcus species.

Willey BM, Jones RN, McGeer A, Witte W, French G, Roberts RB, Jenkins SG, Nadler H, Low DE.

Diagn Microbiol Infect Dis. 1999 Jul;34(3):165-71.


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