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Items: 33

1.

A comparative analysis of the capacity of the Candida species to elicit vaginal immunopathology.

Willems HME, Lowes DJ, Barker KS, Palmer GE, Peters BM.

Infect Immun. 2018 Sep 24. pii: IAI.00527-18. doi: 10.1128/IAI.00527-18. [Epub ahead of print]

PMID:
30249743
2.

Loss of Upc2p-Inducible ERG3 Transcription Is Sufficient To Confer Niche-Specific Azole Resistance without Compromising Candida albicans Pathogenicity.

Luna-Tapia A, Willems HME, Parker JE, Tournu H, Barker KS, Nishimoto AT, Rogers PD, Kelly SL, Peters BM, Palmer GE.

MBio. 2018 May 22;9(3). pii: e00225-18. doi: 10.1128/mBio.00225-18.

3.

Candidalysin drives epithelial signaling, neutrophil recruitment, and immunopathology at the vaginal mucosa.

Richardson JP, Willems HME, Moyes DL, Shoaie S, Barker KS, Tan SL, Palmer GE, Hube B, Naglik JR, Peters BM.

Infect Immun. 2017 Nov 6. pii: IAI.00645-17. doi: 10.1128/IAI.00645-17. [Epub ahead of print]

4.

Diet and Exercise: a Match Made in Bone.

Willems HME, van den Heuvel EGHM, Schoemaker RJW, Klein-Nulend J, Bakker AD.

Curr Osteoporos Rep. 2017 Dec;15(6):555-563. doi: 10.1007/s11914-017-0406-8. Review.

5.

Overexpression of Candida albicans Secreted Aspartyl Proteinases 2 or 5 is not sufficient for exacerbation of immunopathology in a murine model of vaginitis.

Willems HME, Bruner WS, Barker KS, Liu J, Palmer GE, Peters BM.

Infect Immun. 2017 Jul 31. pii: IAI.00248-17. doi: 10.1128/IAI.00248-17. [Epub ahead of print]

6.

Candida-Bacteria Interactions: Their Impact on Human Disease.

Allison DL, Willems HM, Jayatilake JA, Bruno VM, Peters BM, Shirtliff ME.

Microbiol Spectr. 2016 Jun;4(3). doi: 10.1128/microbiolspec.VMBF-0030-2016. Review.

PMID:
27337476
7.

Candida albicans in Multispecies Oral Communities; A Keystone Commensal?

Janus MM, Willems HM, Krom BP.

Adv Exp Med Biol. 2016;931:13-20. doi: 10.1007/5584_2016_5. Review.

PMID:
27271681
8.

Polymicrobial Biofilm Studies: From Basic Science to Biofilm Control.

Willems HM, Xu Z, Peters BM.

Curr Oral Health Rep. 2016 Mar;3(1):36-44. Epub 2016 Jan 14.

9.

Candida albicans in oral biofilms could prevent caries.

Willems HM, Kos K, Jabra-Rizk MA, Krom BP.

Pathog Dis. 2016 Jul;74(5). pii: ftw039. doi: 10.1093/femspd/ftw039. Epub 2016 Apr 28.

PMID:
27129365
10.

Monoacidic Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1:NRF2) Protein-Protein Interaction with High Cell Potency Identified by Fragment-Based Discovery.

Davies TG, Wixted WE, Coyle JE, Griffiths-Jones C, Hearn K, McMenamin R, Norton D, Rich SJ, Richardson C, Saxty G, Willems HM, Woolford AJ, Cottom JE, Kou JP, Yonchuk JG, Feldser HG, Sanchez Y, Foley JP, Bolognese BJ, Logan G, Podolin PL, Yan H, Callahan JF, Heightman TD, Kerns JK.

J Med Chem. 2016 Apr 28;59(8):3991-4006. doi: 10.1021/acs.jmedchem.6b00228. Epub 2016 Apr 12.

PMID:
27031670
11.

Fine-Tuning Covalent Inhibition of Bacterial Quorum Sensing.

Amara N, Gregor R, Rayo J, Dandela R, Daniel E, Liubin N, Willems HM, Ben-Zvi A, Krom BP, Meijler MM.

Chembiochem. 2016 May 3;17(9):825-35. doi: 10.1002/cbic.201500676. Epub 2016 Mar 15.

PMID:
26840534
12.

In Vitro Models for Candida Biofilm Development.

Krom BP, Willems HM.

Methods Mol Biol. 2016;1356:95-105. doi: 10.1007/978-1-4939-3052-4_8.

PMID:
26519068
13.

VDR dependent and independent effects of 1,25-dihydroxyvitamin D3 on nitric oxide production by osteoblasts.

Willems HM, van den Heuvel EG, Carmeliet G, Schaafsma A, Klein-Nulend J, Bakker AD.

Steroids. 2012 Jan;77(1-2):126-31. doi: 10.1016/j.steroids.2011.10.015. Epub 2011 Nov 7.

PMID:
22093484
14.

Mechanical loading stimulates BMP7, but not BMP2, production by osteocytes.

Santos A, Bakker AD, Willems HM, Bravenboer N, Bronckers AL, Klein-Nulend J.

Calcif Tissue Int. 2011 Oct;89(4):318-26. doi: 10.1007/s00223-011-9521-1. Epub 2011 Aug 13.

PMID:
21842277
15.

Fluoride inhibits the response of bone cells to mechanical loading.

Willems HM, van den Heuvel EG, Castelein S, Buisman JK, Bronckers AL, Bakker AD, Klein-Nulend J.

Odontology. 2011 Jul;99(2):112-8. doi: 10.1007/s10266-011-0013-6. Epub 2011 May 7.

PMID:
21553070
16.

De novo ligand design to partially flexible active sites: application of the ReFlex algorithm to carboxypeptidase A, acetylcholinesterase, and the estrogen receptor.

Firth-Clark S, Kirton SB, Willems HM, Williams A.

J Chem Inf Model. 2008 Feb;48(2):296-305. doi: 10.1021/ci700282u. Epub 2008 Jan 31.

PMID:
18232679
17.

Small-molecule inhibitors of the MDM2-p53 protein-protein interaction based on an isoindolinone scaffold.

Hardcastle IR, Ahmed SU, Atkins H, Farnie G, Golding BT, Griffin RJ, Guyenne S, Hutton C, Källblad P, Kemp SJ, Kitching MS, Newell DR, Norbedo S, Northen JS, Reid RJ, Saravanan K, Willems HM, Lunec J.

J Med Chem. 2006 Oct 19;49(21):6209-21.

PMID:
17034127
18.

Generation and selection of novel estrogen receptor ligands using the de novo structure-based design tool, SkelGen.

Firth-Clark S, Willems HM, Williams A, Harris W.

J Chem Inf Model. 2006 Mar-Apr;46(2):642-7.

PMID:
16562994
19.

Occupational asthma prevention and management in industry--an example of a global programme.

Gannon PF, Berg AS, Gayosso R, Henderson B, Sax SE, Willems HM.

Occup Med (Lond). 2005 Dec;55(8):600-5.

PMID:
16314331
20.

Isoindolinone-based inhibitors of the MDM2-p53 protein-protein interaction.

Hardcastle IR, Ahmed SU, Atkins H, Calvert AH, Curtin NJ, Farnie G, Golding BT, Griffin RJ, Guyenne S, Hutton C, Källblad P, Kemp SJ, Kitching MS, Newell DR, Norbedo S, Northen JS, Reid RJ, Saravanan K, Willems HM, Lunec J.

Bioorg Med Chem Lett. 2005 Mar 1;15(5):1515-20.

PMID:
15713419
21.

Receptor flexibility in the in silico screening of reagents in the S1' pocket of human collagenase.

Källblad P, Todorov NP, Willems HM, Alberts IL.

J Med Chem. 2004 May 20;47(11):2761-7.

PMID:
15139754
22.
23.

Identification of F11 fimbriae on chicken Escherichia coli strains.

van den Bosch JF, Hendriks JH, Gladigau I, Willems HM, Storm PK, de Graaf FK.

Infect Immun. 1993 Mar;61(3):800-6.

24.

WT1: a monoclonal antibody reactive with T-ALL but not with other leukemias.

Tax WJ, Greaves MF, Willems HM, Leeuwenberg HF, Capel PJ, Koene RA.

Haematol Blood Transfus. 1983;28:139-41. No abstract available.

PMID:
6602735
25.

Influence of resistance-factors on the phage types of Salmonella panama.

Guinée PA, Scholtens RT, Willems HM.

Antonie Van Leeuwenhoek. 1967;33(1):30-40. No abstract available.

PMID:
5340158
26.

Restriction and modification of phage 47 and lambda by R factors.

Guinée PA, Willems HM.

Antonie Van Leeuwenhoek. 1967;33(4):397-406. No abstract available.

PMID:
4866757
27.

Seven new Salmonella types: S. leiden, S. lawra, S. hillegersberg, S. enschede, S. overvecht, S. woerden and S. odijk.

Guinée PA, Willems HM.

Antonie Van Leeuwenhoek. 1966;32(3):333-6. No abstract available.

PMID:
5296757
28.

Experimental studies to determine the temperature and duration of heat treatment required for decontamination of feed meals.

Kampelmacher EH, Guinée PA, van Schothorst M, Willems HM.

Zentralbl Veterinarmed B. 1965 Feb;12(1):50-4. No abstract available.

PMID:
5890710
29.
30.

Eight new Salmonella types (S. houten, S. tuindorp, S.vleuten, S. zeist, S. soesterberg, S. kralingen, S. assen).

GUINEE PA, KAMPELMACHER EH, WILLEMS HM.

Antonie Van Leeuwenhoek. 1962;28:284-8. No abstract available.

PMID:
13963471
31.

On antigenic H-relationships between the groups Salmonella, Arizona and Escherichia coli.

GUINEE PA, KAMPELMACHER EH, WILLEMS HM.

Antonie Van Leeuwenhoek. 1962;28:17-45. No abstract available.

PMID:
13902865
32.

Three new Salmonella types (S. bilthoven, S. wassenaar and S. bonaire).

GUINEE PA, KAMPELMACHER EH, WILLEMS HM.

Antonie Van Leeuwenhoek. 1961;27:465-8. No abstract available.

PMID:
13902867
33.

Six new Salmonella types, isolated in Ghana (S. volta, S. agona, S. wa, S. techimani, S. mampong and S. tafo).

GUINEE PA, KAMPELMACHER EH, WILLEMS HM.

Antonie Van Leeuwenhoek. 1961;27:469-72. No abstract available.

PMID:
13902866

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