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Items: 1 to 50 of 213

1.

Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity.

Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ.

Nat Commun. 2019 Aug 21;10(1):3767. doi: 10.1038/s41467-019-11783-9.

2.

Tuberculosis antigen-specific T cell responses during the first 6 months of antiretroviral treatment.

Riou C, Jhilmeet N, Rangaka MX, Wilkinson RJ, Wilkinson KA.

J Infect Dis. 2019 Aug 17. pii: jiz417. doi: 10.1093/infdis/jiz417. [Epub ahead of print]

3.

Clinical, microbiologic, and immunologic determinants of mortality in hospitalized patients with HIV-associated tuberculosis: A prospective cohort study.

Schutz C, Barr D, Andrade BB, Shey M, Ward A, Janssen S, Burton R, Wilkinson KA, Sossen B, Fukutani KF, Nicol M, Maartens G, Wilkinson RJ, Meintjes G.

PLoS Med. 2019 Jul 5;16(7):e1002840. doi: 10.1371/journal.pmed.1002840. eCollection 2019 Jul.

4.

Invariant Natural Killer T cell dynamics in HIV-associated tuberculosis.

Walker NF, Opondo C, Meintjes G, Jhilmeet N, Friedland JS, Elkington PT, Wilkinson RJ, Wilkinson KA.

Clin Infect Dis. 2019 Jun 12. pii: ciz501. doi: 10.1093/cid/ciz501. [Epub ahead of print]

5.

Parkin-mediated ubiquitination contributes to the constitutive turnover of mitochondrial fission factor (Mff).

Lee L, Seager R, Nakamura Y, Wilkinson KA, Henley JM.

PLoS One. 2019 May 21;14(5):e0213116. doi: 10.1371/journal.pone.0213116. eCollection 2019.

6.

The C-terminal helix 9 motif in rat cannabinoid receptor type 1 regulates axonal trafficking and surface expression.

Fletcher-Jones A, Hildick KL, Evans AJ, Nakamura Y, Wilkinson KA, Henley JM.

Elife. 2019 Apr 30;8. pii: e44252. doi: 10.7554/eLife.44252.

7.

Insulin-dependent GLUT4 trafficking is not regulated by protein SUMOylation in L6 myocytes.

Carmichael RE, Wilkinson KA, Craig TJ.

Sci Rep. 2019 Apr 24;9(1):6477. doi: 10.1038/s41598-019-42574-3.

8.

Protective role of the deSUMOylating enzyme SENP3 in myocardial ischemia-reperfusion injury.

Rawlings N, Lee L, Nakamura Y, Wilkinson KA, Henley JM.

PLoS One. 2019 Apr 11;14(4):e0213331. doi: 10.1371/journal.pone.0213331. eCollection 2019.

9.

Matrix Metalloproteinases in Pulmonary and Central Nervous System Tuberculosis-A Review.

Rohlwink UK, Walker NF, Ordonez AA, Li YJ, Tucker EW, Elkington PT, Wilkinson RJ, Wilkinson KA.

Int J Mol Sci. 2019 Mar 18;20(6). pii: E1350. doi: 10.3390/ijms20061350. Review.

10.

Developmental profiles of SUMOylation pathway proteins in rat cerebrum and cerebellum.

Josa-Prado F, Luo J, Rubin P, Henley JM, Wilkinson KA.

PLoS One. 2019 Feb 22;14(2):e0212857. doi: 10.1371/journal.pone.0212857. eCollection 2019.

11.

Elevated Matrix Metalloproteinase Concentrations Offer Novel Insight Into Their Role in Pediatric Tuberculous Meningitis.

Li YJ, Wilkinson KA, Wilkinson RJ, Figaji AA, Rohlwink UK.

J Pediatric Infect Dis Soc. 2019 Feb 12. doi: 10.1093/jpids/piy141. [Epub ahead of print]

12.

Acetylcholine receptors in the equatorial region of intrafusal muscle fibres modulate mouse muscle spindle sensitivity.

Gerwin L, Haupt C, Wilkinson KA, Kröger S.

J Physiol. 2019 Apr;597(7):1993-2006. doi: 10.1113/JP277139. Epub 2019 Feb 13.

PMID:
30673133
13.

Sorting nexin 27 rescues neuroligin 2 from lysosomal degradation to control inhibitory synapse number.

Binda CS, Nakamura Y, Henley JM, Wilkinson KA.

Biochem J. 2019 Jan 25;476(2):293-306. doi: 10.1042/BCJ20180504.

PMID:
30602588
14.

The effect of antiretroviral treatment on selected genes in whole blood from HIV-infected adults sensitised by Mycobacterium tuberculosis.

Jhilmeet N, Lowe DM, Riou C, Scriba TJ, Coussens A, Goliath R, Wilkinson RJ, Wilkinson KA.

PLoS One. 2018 Dec 27;13(12):e0209516. doi: 10.1371/journal.pone.0209516. eCollection 2018.

15.

ADAR2-mediated Q/R editing of GluK2 regulates kainate receptor upscaling in response to suppression of synaptic activity.

Gurung S, Evans AJ, Wilkinson KA, Henley JM.

J Cell Sci. 2018 Dec 17;131(24). pii: jcs222273. doi: 10.1242/jcs.222273.

16.

Post-translational modifications of Parkinson's disease-related proteins: Phosphorylation, SUMOylation and Ubiquitination.

Junqueira SC, Centeno EGZ, Wilkinson KA, Cimarosti H.

Biochim Biophys Acta Mol Basis Dis. 2019 Aug 1;1865(8):2001-2007. doi: 10.1016/j.bbadis.2018.10.025. Epub 2018 Nov 6.

PMID:
30412791
17.

Plasma Biomarkers to Detect Prevalent or Predict Progressive Tuberculosis Associated With Human Immunodeficiency Virus-1.

Lesosky M, Rangaka MX, Pienaar C, Coussens AK, Goliath R, Mathee S, Mwansa-Kambafwile J, Maartens G, Wilkinson RJ, Wilkinson KA.

Clin Infect Dis. 2019 Jul 2;69(2):295-305. doi: 10.1093/cid/ciy823.

18.

Lipopolysaccharide-induced inflammation does not alter muscle spindle afferent mechanosensation or sensory integration in the spinal cord of adult mice.

Zaytseva D, Allawala A, Franco JA, Putnam S, Abtahie AM, Bubalo N, Criddle CR, Nguyen TA, Nguyen P, Padmanabhan S, Sanghera P, Bremer M, Abramson T, Wilkinson KA.

Physiol Rep. 2018 Sep;6(17):e13812. doi: 10.14814/phy2.13812.

19.

Differential Effect of Viable Versus Necrotic Neutrophils on Mycobacterium tuberculosis Growth and Cytokine Induction in Whole Blood.

Lowe DM, Demaret J, Bangani N, Nakiwala JK, Goliath R, Wilkinson KA, Wilkinson RJ, Martineau AR.

Front Immunol. 2018 Apr 27;9:903. doi: 10.3389/fimmu.2018.00903. eCollection 2018.

20.

Effect of prednisolone on inflammatory markers in pericardial tuberculosis: A pilot study.

Shenje J, Lai RP, Ross IL, Mayosi BM, Wilkinson RJ, Ntsekhe M, Wilkinson KA.

Int J Cardiol Heart Vasc. 2017 Nov 3;18:104-108. doi: 10.1016/j.ijcha.2017.10.002. eCollection 2018 Mar.

21.

Diet induced obesity alters muscle spindle afferent function in adult mice.

Elahi LS, Shamai KN, Abtahie AM, Cai AM, Padmanabhan S, Bremer M, Wilkinson KA.

PLoS One. 2018 May 2;13(5):e0196832. doi: 10.1371/journal.pone.0196832. eCollection 2018.

22.

The transcription factor MEF2A plays a key role in the differentiation/maturation of rat neural stem cells into neurons.

Zhu B, Carmichael RE, Solabre Valois L, Wilkinson KA, Henley JM.

Biochem Biophys Res Commun. 2018 Jun 7;500(3):645-649. doi: 10.1016/j.bbrc.2018.04.125. Epub 2018 Apr 23.

23.

Contribution of APCs to mucosal-associated invariant T cell activation in infectious disease and cancer.

Shey MS, Balfour A, Wilkinson KA, Meintjes G.

Innate Immun. 2018 May;24(4):192-202. doi: 10.1177/1753425918768695. Epub 2018 Apr 9. Review.

24.

MEF2A regulates mGluR-dependent AMPA receptor trafficking independently of Arc/Arg3.1.

Carmichael RE, Wilkinson KA, Craig TJ, Ashby MC, Henley JM.

Sci Rep. 2018 Mar 27;8(1):5263. doi: 10.1038/s41598-018-23440-0.

25.

Age cannot wither her? - NCEPOD at 30.

Goodwin APL, Wilkinson KA.

Anaesthesia. 2018 Aug;73(8):931-934. doi: 10.1111/anae.14272. Epub 2018 Mar 25. No abstract available.

26.

Extranuclear SUMOylation in Neurons.

Henley JM, Carmichael RE, Wilkinson KA.

Trends Neurosci. 2018 Apr;41(4):198-210. doi: 10.1016/j.tins.2018.02.004. Epub 2018 Mar 9. Review.

PMID:
29530319
27.

The Immune Response to Mycobacterium tuberculosis in HIV-1-Coinfected Persons.

Esmail H, Riou C, Bruyn ED, Lai RP, Harley YXR, Meintjes G, Wilkinson KA, Wilkinson RJ.

Annu Rev Immunol. 2018 Apr 26;36:603-638. doi: 10.1146/annurev-immunol-042617-053420. Epub 2018 Feb 28. Review.

PMID:
29490165
28.

Complement pathway gene activation and rising circulating immune complexes characterize early disease in HIV-associated tuberculosis.

Esmail H, Lai RP, Lesosky M, Wilkinson KA, Graham CM, Horswell S, Coussens AK, Barry CE 3rd, O'Garra A, Wilkinson RJ.

Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):E964-E973. doi: 10.1073/pnas.1711853115. Epub 2018 Jan 16.

29.

Exciting Times: New Advances Towards Understanding the Regulation and Roles of Kainate Receptors.

Evans AJ, Gurung S, Henley JM, Nakamura Y, Wilkinson KA.

Neurochem Res. 2019 Mar;44(3):572-584. doi: 10.1007/s11064-017-2450-2. Epub 2017 Dec 21. Review.

30.

Commentary: Analysis of SUMO1-conjugation at synapses.

Wilkinson KA, Martin S, Tyagarajan SK, Arancio O, Craig TJ, Guo C, Fraser PE, Goldstein SAN, Henley JM.

Front Cell Neurosci. 2017 Oct 30;11:345. doi: 10.3389/fncel.2017.00345. eCollection 2017. No abstract available.

31.

Neutrophil Activation and Enhanced Release of Granule Products in HIV-TB Immune Reconstitution Inflammatory Syndrome.

Nakiwala JK, Walker NF, Diedrich CR, Worodria W, Meintjes G, Wilkinson RJ, Mayanja-Kizza H, Colebunders R, Kestens L, Wilkinson KA, Lowe DM.

J Acquir Immune Defic Syndr. 2018 Feb 1;77(2):221-229. doi: 10.1097/QAI.0000000000001582. Erratum in: J Acquir Immune Defic Syndr. 2018 Jun 1;78(2):e13.

32.

Density, abundance, survival, and ranging patterns of common bottlenose dolphins (Tursiops truncatus) in Mississippi Sound following the Deepwater Horizon oil spill.

Mullin KD, McDonald T, Wells RS, Balmer BC, Speakman T, Sinclair C, Zolman ES, Hornsby F, McBride SM, Wilkinson KA, Schwacke LH.

PLoS One. 2017 Oct 20;12(10):e0186265. doi: 10.1371/journal.pone.0186265. eCollection 2017.

33.

Do General Practitioners Follow Guidelines on the Use of Antidepressants To Treat Depression? Can the Situation Be Improved?

Wang S, Wilkinson KA, Agius M.

Psychiatr Danub. 2017 Sep;29(Suppl 3):236-240. Review.

PMID:
28953769
34.

Increased SUMO-2/3-ylation mediated by SENP3 degradation is protective against cadmium-induced caspase 3-dependent cytotoxicity.

Luo J, Gurung S, Lee L, Henley JM, Wilkinson KA, Guo C.

J Toxicol Sci. 2017;42(5):529-538. doi: 10.2131/jts.42.529.

35.

Assembly, Secretory Pathway Trafficking, and Surface Delivery of Kainate Receptors Is Regulated by Neuronal Activity.

Evans AJ, Gurung S, Wilkinson KA, Stephens DJ, Henley JM.

Cell Rep. 2017 Jun 20;19(12):2613-2626. doi: 10.1016/j.celrep.2017.06.001.

36.

Biomarkers of Cerebral Injury and Inflammation in Pediatric Tuberculous Meningitis.

Rohlwink UK, Mauff K, Wilkinson KA, Enslin N, Wegoye E, Wilkinson RJ, Figaji AA.

Clin Infect Dis. 2017 Oct 15;65(8):1298-1307. doi: 10.1093/cid/cix540.

37.

Mycobacterium tuberculosis Induction of Heme Oxygenase-1 Expression Is Dependent on Oxidative Stress and Reflects Treatment Outcomes.

Rockwood N, Costa DL, Amaral EP, Du Bruyn E, Kubler A, Gil-Santana L, Fukutani KF, Scanga CA, Flynn JL, Jackson SH, Wilkinson KA, Bishai WR, Sher A, Wilkinson RJ, Andrade BB.

Front Immunol. 2017 May 12;8:542. doi: 10.3389/fimmu.2017.00542. eCollection 2017.

38.

Formicamycins, antibacterial polyketides produced by Streptomyces formicae isolated from African Tetraponera plant-ants.

Qin Z, Munnoch JT, Devine R, Holmes NA, Seipke RF, Wilkinson KA, Wilkinson B, Hutchings MI.

Chem Sci. 2017 Apr 1;8(4):3218-3227. doi: 10.1039/c6sc04265a. Epub 2017 Feb 13.

39.

Matrix Degradation in Human Immunodeficiency Virus Type 1-Associated Tuberculosis and Tuberculosis Immune Reconstitution Inflammatory Syndrome: A Prospective Observational Study.

Walker NF, Wilkinson KA, Meintjes G, Tezera LB, Goliath R, Peyper JM, Tadokera R, Opondo C, Coussens AK, Wilkinson RJ, Friedland JS, Elkington PT.

Clin Infect Dis. 2017 Jul 1;65(1):121-132. doi: 10.1093/cid/cix231.

40.

SUMOylation of FOXP1 regulates transcriptional repression via CtBP1 to drive dendritic morphogenesis.

Rocca DL, Wilkinson KA, Henley JM.

Sci Rep. 2017 Apr 13;7(1):877. doi: 10.1038/s41598-017-00707-6.

41.

Mortality in Severe Human Immunodeficiency Virus-Tuberculosis Associates With Innate Immune Activation and Dysfunction of Monocytes.

Janssen S, Schutz C, Ward A, Nemes E, Wilkinson KA, Scriven J, Huson MA, Aben N, Maartens G, Burton R, Wilkinson RJ, Grobusch MP, Van der Poll T, Meintjes G.

Clin Infect Dis. 2017 Jul 1;65(1):73-82. doi: 10.1093/cid/cix254.

42.

Hemostatic Changes Associated With Increased Mortality Rates in Hospitalized Patients With HIV-Associated Tuberculosis: A Prospective Cohort Study.

Janssen S, Schutz C, Ward AM, Huson MA, Wilkinson RJ, Burton R, Maartens G, Wilkinson KA, Meijers JC, Lutter R, Grobusch MP, Meintjes G, van der Poll T.

J Infect Dis. 2017 Jan 15;215(2):247-258. doi: 10.1093/infdis/jiw532.

43.

The CSF Immune Response in HIV-1-Associated Cryptococcal Meningitis: Macrophage Activation, Correlates of Disease Severity, and Effect of Antiretroviral Therapy.

Scriven JE, Graham LM, Schutz C, Scriba TJ, Wilkinson KA, Wilkinson RJ, Boulware DR, Urban BC, Meintjes G, Lalloo DG.

J Acquir Immune Defic Syndr. 2017 Jul 1;75(3):299-307. doi: 10.1097/QAI.0000000000001382.

44.

SENP3-mediated deSUMOylation of Drp1 facilitates interaction with Mff to promote cell death.

Guo C, Wilkinson KA, Evans AJ, Rubin PP, Henley JM.

Sci Rep. 2017 Mar 6;7:43811. doi: 10.1038/srep43811.

45.

Expansion of the molecular and morphological diversity of Acanthamoebidae (Centramoebida, Amoebozoa) and identification of a novel life cycle type within the group.

Tice AK, Shadwick LL, Fiore-Donno AM, Geisen S, Kang S, Schuler GA, Spiegel FW, Wilkinson KA, Bonkowski M, Dumack K, Lahr DJ, Voelcker E, Clauß S, Zhang J, Brown MW.

Biol Direct. 2016 Dec 28;11(1):69. doi: 10.1186/s13062-016-0171-0.

46.

Inflammasome Activation Underlying Central Nervous System Deterioration in HIV-Associated Tuberculosis.

Marais S, Lai RPJ, Wilkinson KA, Meintjes G, O'Garra A, Wilkinson RJ.

J Infect Dis. 2017 Mar 1;215(5):677-686. doi: 10.1093/infdis/jiw561.

47.

The bacillary and macrophage response to hypoxia in tuberculosis and the consequences for T cell antigen recognition.

Prosser G, Brandenburg J, Reiling N, Barry CE 3rd, Wilkinson RJ, Wilkinson KA.

Microbes Infect. 2017 Mar;19(3):177-192. doi: 10.1016/j.micinf.2016.10.001. Epub 2016 Oct 22. Review.

48.

QuantiFERON conversion following tuberculin administration is common in HIV infection and relates to baseline response.

Esmail H, Thienemann F, Oni T, Goliath R, Wilkinson KA, Wilkinson RJ.

BMC Infect Dis. 2016 Oct 7;16(1):545.

49.

Characterization of progressive HIV-associated tuberculosis using 2-deoxy-2-[18F]fluoro-D-glucose positron emission and computed tomography.

Esmail H, Lai RP, Lesosky M, Wilkinson KA, Graham CM, Coussens AK, Oni T, Warwick JM, Said-Hartley Q, Koegelenberg CF, Walzl G, Flynn JL, Young DB, Barry Iii CE, O'Garra A, Wilkinson RJ.

Nat Med. 2016 Oct;22(10):1090-1093. doi: 10.1038/nm.4161. Epub 2016 Sep 5.

50.

Atypical parkinsonism-associated retromer mutant alters endosomal sorting of specific cargo proteins.

McMillan KJ, Gallon M, Jellett AP, Clairfeuille T, Tilley FC, McGough I, Danson CM, Heesom KJ, Wilkinson KA, Collins BM, Cullen PJ.

J Cell Biol. 2016 Aug 15;214(4):389-99. doi: 10.1083/jcb.201604057.

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