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Items: 1 to 50 of 176

1.

The PHLPP2 phosphatase is a druggable driver of prostate cancer progression.

Nowak DG, Katsenelson KC, Watrud KE, Chen M, Mathew G, D'Andrea VD, Lee MF, Swamynathan MM, Casanova-Salas I, Jibilian MC, Buckholtz CL, Ambrico AJ, Pan CH, Wilkinson JE, Newton AC, Trotman LC.

J Cell Biol. 2019 May 15. pii: jcb.201902048. doi: 10.1083/jcb.201902048. [Epub ahead of print]

PMID:
31092557
2.

Acarbose improves health and lifespan in aging HET3 mice.

Harrison DE, Strong R, Alavez S, Astle CM, DiGiovanni J, Fernandez E, Flurkey K, Garratt M, Gelfond JAL, Javors MA, Levi M, Lithgow GJ, Macchiarini F, Nelson JF, Sukoff Rizzo SJ, Slaga TJ, Stearns T, Wilkinson JE, Miller RA.

Aging Cell. 2019 Apr;18(2):e12898. doi: 10.1111/acel.12898. Epub 2019 Jan 27.

3.

Arid1a restrains Kras-dependent changes in acinar cell identity.

Livshits G, Alonso-Curbelo D, Morris JP 4th, Koche R, Saborowski M, Wilkinson JE, Lowe SW.

Elife. 2018 Jul 17;7. pii: e35216. doi: 10.7554/eLife.35216.

4.

POU2F3 is a master regulator of a tuft cell-like variant of small cell lung cancer.

Huang YH, Klingbeil O, He XY, Wu XS, Arun G, Lu B, Somerville TDD, Milazzo JP, Wilkinson JE, Demerdash OE, Spector DL, Egeblad M, Shi J, Vakoc CR.

Genes Dev. 2018 Jul 1;32(13-14):915-928. doi: 10.1101/gad.314815.118. Epub 2018 Jun 26.

5.

Sex-related differences in the thanatomicrobiome in postmortem heart samples using bacterial gene regions V1-2 and V4.

Bell CR, Wilkinson JE, Robertson BK, Javan GT.

Lett Appl Microbiol. 2018 Aug;67(2):144-153. doi: 10.1111/lam.13005. Epub 2018 Jun 6.

PMID:
29747223
6.

Traditional culture methods fail to detect principle pathogens in necrotising soft tissue infection: a case report.

Zhao-Fleming HH, Barake SRS, Hand A, Wilkinson JE, Sanford N, Winn R, Dissanaike S.

J Wound Care. 2018 Apr 1;27(Sup4):S24-S28. doi: 10.12968/jowc.2018.27.Sup4.S24.

PMID:
29641341
7.

Erratum: Asparagine bioavailability governs metastasis in a model of breast cancer.

Knott SRV, Wagenblast E, Khan S, Kim SY, Soto M, Wagner M, Turgeon MO, Fish L, Erard N, Gable AL, Maceli AR, Dickopf S, Papachristou EK, D'Santos CS, Carey LA, Wilkinson JE, Harrell JC, Perou CM, Goodarzi H, Poulogiannis G, Hannon GJ.

Nature. 2018 Apr 4;556(7699):135. doi: 10.1038/nature26162.

PMID:
29620732
8.

Asparagine bioavailability governs metastasis in a model of breast cancer.

Knott SRV, Wagenblast E, Khan S, Kim SY, Soto M, Wagner M, Turgeon MO, Fish L, Erard N, Gable AL, Maceli AR, Dickopf S, Papachristou EK, D'Santos CS, Carey LA, Wilkinson JE, Harrell JC, Perou CM, Goodarzi H, Poulogiannis G, Hannon GJ.

Nature. 2018 Feb 15;554(7692):378-381. doi: 10.1038/nature25465. Epub 2018 Feb 7. Erratum in: Nature. 2018 Apr 4;556(7699):135.

9.

Efficacy of hyperbaric oxygen therapy in bacterial biofilm eradication.

Sanford NE, Wilkinson JE, Nguyen H, Diaz G, Wolcott R.

J Wound Care. 2018 Jan 1;27(Sup1):S20-S28. doi: 10.12968/jowc.2018.27.Sup1.S20.

PMID:
29334015
10.

A TFIID-SAGA Perturbation that Targets MYB and Suppresses Acute Myeloid Leukemia.

Xu Y, Milazzo JP, Somerville TDD, Tarumoto Y, Huang YH, Ostrander EL, Wilkinson JE, Challen GA, Vakoc CR.

Cancer Cell. 2018 Jan 8;33(1):13-28.e8. doi: 10.1016/j.ccell.2017.12.002.

11.

Apoptosis-induced CXCL5 accelerates inflammation and growth of prostate tumor metastases in bone.

Roca H, Jones JD, Purica MC, Weidner S, Koh AJ, Kuo R, Wilkinson JE, Wang Y, Daignault-Newton S, Pienta KJ, Morgan TM, Keller ET, Nör JE, Shea LD, McCauley LK.

J Clin Invest. 2018 Jan 2;128(1):248-266. doi: 10.1172/JCI92466. Epub 2017 Nov 27.

12.

Doxycycline induces dysbiosis in female C57BL/6NCrl mice.

Boynton FDD, Ericsson AC, Uchihashi M, Dunbar ML, Wilkinson JE.

BMC Res Notes. 2017 Nov 29;10(1):644. doi: 10.1186/s13104-017-2960-7.

13.

Cadaver Thanatomicrobiome Signatures: The Ubiquitous Nature of Clostridium Species in Human Decomposition.

Javan GT, Finley SJ, Smith T, Miller J, Wilkinson JE.

Front Microbiol. 2017 Oct 30;8:2096. doi: 10.3389/fmicb.2017.02096. eCollection 2017.

14.

DNAJB1-PRKACA fusion kinase interacts with β-catenin and the liver regenerative response to drive fibrolamellar hepatocellular carcinoma.

Kastenhuber ER, Lalazar G, Houlihan SL, Tschaharganeh DF, Baslan T, Chen CC, Requena D, Tian S, Bosbach B, Wilkinson JE, Simon SM, Lowe SW.

Proc Natl Acad Sci U S A. 2017 Dec 12;114(50):13076-13084. doi: 10.1073/pnas.1716483114. Epub 2017 Nov 21.

15.

Suppression of protein tyrosine phosphatase N23 predisposes to breast tumorigenesis via activation of FYN kinase.

Zhang S, Fan G, Hao Y, Hammell M, Wilkinson JE, Tonks NK.

Genes Dev. 2017 Oct 1;31(19):1939-1957. doi: 10.1101/gad.304261.117. Epub 2017 Oct 24.

16.

R-Spondin chromosome rearrangements drive Wnt-dependent tumour initiation and maintenance in the intestine.

Han T, Schatoff EM, Murphy C, Zafra MP, Wilkinson JE, Elemento O, Dow LE.

Nat Commun. 2017 Jul 11;8:15945. doi: 10.1038/ncomms15945.

17.

Microbiome Structural and Functional Interactions across Host Dietary Niche Space.

Phillips CD, Hanson J, Wilkinson JE, Koenig L, Rees E, Webala P, Kingston T.

Integr Comp Biol. 2017 Oct 1;57(4):743-755. doi: 10.1093/icb/icx011.

PMID:
28662574
18.

Postmortem microbial communities in burial soil layers of skeletonized humans.

Thomas TB, Finley SJ, Wilkinson JE, Wescott DJ, Gorski A, Javan GT.

J Forensic Leg Med. 2017 Jul;49:43-49. doi: 10.1016/j.jflm.2017.05.009. Epub 2017 May 3.

PMID:
28527363
19.

Nanoemulsion is an effective antimicrobial for methicillin-resistant Staphylococcus aureus in infected wounds.

Cao Z, Spilker T, Fan Y, Kalikin LM, Ciotti S, LiPuma JJ, Makidon PE, Wilkinson JE, Baker JR Jr, Wang SH.

Nanomedicine (Lond). 2017 May;12(10):1177-1185. doi: 10.2217/nnm-2017-0025. Epub 2017 Apr 27.

PMID:
28447896
20.

The nuclear transport receptor Importin-11 is a tumor suppressor that maintains PTEN protein.

Chen M, Nowak DG, Narula N, Robinson B, Watrud K, Ambrico A, Herzka TM, Zeeman ME, Minderer M, Zheng W, Ebbesen SH, Plafker KS, Stahlhut C, Wang VM, Wills L, Nasar A, Castillo-Martin M, Cordon-Cardo C, Wilkinson JE, Powers S, Sordella R, Altorki NK, Mittal V, Stiles BM, Plafker SM, Trotman LC.

J Cell Biol. 2017 Mar 6;216(3):641-656. doi: 10.1083/jcb.201604025. Epub 2017 Feb 13.

21.

A Pipeline for Drug Target Identification and Validation.

Manchado E, Huang CH, Tasdemir N, Tschaharganeh DF, Wilkinson JE, Lowe SW.

Cold Spring Harb Symp Quant Biol. 2016;81:257-267. doi: 10.1101/sqb.2016.81.031096. Epub 2017 Jan 5. Review.

22.

Overactive mTOR signaling leads to endometrial hyperplasia in aged women and mice.

Bajwa P, Nielsen S, Lombard JM, Rassam L, Nahar P, Rueda BR, Wilkinson JE, Miller RA, Tanwar PS.

Oncotarget. 2017 Jan 31;8(5):7265-7275. doi: 10.18632/oncotarget.13919.

23.

Microbiota is a primary cause of pathogenesis of chronic wounds.

Wolcott R, Sanford N, Gabrilska R, Oates JL, Wilkinson JE, Rumbaugh KP.

J Wound Care. 2016 Oct 1;25(Sup10):S33-S43. doi: 10.12968/jowc.2016.25.Sup10.S33.

PMID:
27681809
24.

Fate and impact of zero-valent copper nanoparticles on geographically-distinct soils.

Shah V, Luxton TP, Walker VK, Brumfield T, Yost J, Shah S, Wilkinson JE, Kambhampati M.

Sci Total Environ. 2016 Dec 15;573:661-670. doi: 10.1016/j.scitotenv.2016.08.114. Epub 2016 Aug 30.

PMID:
27585433
25.

NRF2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic Cancer.

Chio IIC, Jafarnejad SM, Ponz-Sarvise M, Park Y, Rivera K, Palm W, Wilson J, Sangar V, Hao Y, Öhlund D, Wright K, Filippini D, Lee EJ, Da Silva B, Schoepfer C, Wilkinson JE, Buscaglia JM, DeNicola GM, Tiriac H, Hammell M, Crawford HC, Schmidt EE, Thompson CB, Pappin DJ, Sonenberg N, Tuveson DA.

Cell. 2016 Aug 11;166(4):963-976. doi: 10.1016/j.cell.2016.06.056. Epub 2016 Jul 28.

26.

Human Thanatomicrobiome Succession and Time Since Death.

Javan GT, Finley SJ, Can I, Wilkinson JE, Hanson JD, Tarone AM.

Sci Rep. 2016 Jul 14;6:29598. doi: 10.1038/srep29598.

27.

Age related increase in mTOR activity contributes to the pathological changes in ovarian surface epithelium.

Bajwa P, Nagendra PB, Nielsen S, Sahoo SS, Bielanowicz A, Lombard JM, Wilkinson JE, Miller RA, Tanwar PS.

Oncotarget. 2016 Apr 12;7(15):19214-27. doi: 10.18632/oncotarget.8468.

28.

Differentiation of mammary tumors and reduction in metastasis upon Malat1 lncRNA loss.

Arun G, Diermeier S, Akerman M, Chang KC, Wilkinson JE, Hearn S, Kim Y, MacLeod AR, Krainer AR, Norton L, Brogi E, Egeblad M, Spector DL.

Genes Dev. 2016 Jan 1;30(1):34-51. doi: 10.1101/gad.270959.115. Epub 2015 Dec 23.

30.

ATDC/TRIM29 Drives Invasive Bladder Cancer Formation through miRNA-Mediated and Epigenetic Mechanisms.

Palmbos PL, Wang L, Yang H, Wang Y, Leflein J, Ahmet ML, Wilkinson JE, Kumar-Sinha C, Ney GM, Tomlins SA, Daignault S, Kunju LP, Wu XR, Lotan Y, Liebert M, Ljungman ME, Simeone DM.

Cancer Res. 2015 Dec 1;75(23):5155-66. doi: 10.1158/0008-5472.CAN-15-0603. Epub 2015 Oct 15.

31.

Chronic Dosing with Membrane Sealant Poloxamer 188 NF Improves Respiratory Dysfunction in Dystrophic Mdx and Mdx/Utrophin-/- Mice.

Markham BE, Kernodle S, Nemzek J, Wilkinson JE, Sigler R.

PLoS One. 2015 Aug 6;10(8):e0134832. doi: 10.1371/journal.pone.0134832. eCollection 2015.

32.

Nanoemulsion Therapy for Burn Wounds Is Effective as a Topical Antimicrobial Against Gram-Negative and Gram-Positive Bacteria.

Dolgachev VA, Ciotti SM, Eisma R, Gracon S, Wilkinson JE, Baker JR Jr, Hemmila MR.

J Burn Care Res. 2016 Mar-Apr;37(2):e104-14. doi: 10.1097/BCR.0000000000000217.

33.

Exposure to cold and acute upper respiratory tract infection.

Eccles R, Wilkinson JE.

Rhinology. 2015 Jun;53(2):99-106. doi: 10.4193/Rhin14.239. Review.

PMID:
26030031
34.

A sniff of happiness.

de Groot JH, Smeets MA, Rowson MJ, Bulsing PJ, Blonk CG, Wilkinson JE, Semin GR.

Psychol Sci. 2015 Jun;26(6):684-700. doi: 10.1177/0956797614566318. Epub 2015 Apr 13.

PMID:
25870406
35.

A model of breast cancer heterogeneity reveals vascular mimicry as a driver of metastasis.

Wagenblast E, Soto M, Gutiérrez-Ángel S, Hartl CA, Gable AL, Maceli AR, Erard N, Williams AM, Kim SY, Dickopf S, Harrell JC, Smith AD, Perou CM, Wilkinson JE, Hannon GJ, Knott SR.

Nature. 2015 Apr 16;520(7547):358-62. doi: 10.1038/nature14403. Epub 2015 Apr 8.

36.

Successful Porcine Renal Transplantation After 60 Minutes of Donor Warm Ischemia: Extracorporeal Perfusion and Thrombolytics.

Demos DS, Iyengar A, Bryner BS, Gray BW, Hoffman HR, Cornell MS, Wilkinson JE, Mazur DE, Bartlett RH, Punch JD, Rojas-Peña A.

ASAIO J. 2015 Jul-Aug;61(4):474-9. doi: 10.1097/MAT.0000000000000228.

37.

MYC Drives Pten/Trp53-Deficient Proliferation and Metastasis due to IL6 Secretion and AKT Suppression via PHLPP2.

Nowak DG, Cho H, Herzka T, Watrud K, DeMarco DV, Wang VM, Senturk S, Fellmann C, Ding D, Beinortas T, Kleinman D, Chen M, Sordella R, Wilkinson JE, Castillo-Martin M, Cordon-Cardo C, Robinson BD, Trotman LC.

Cancer Discov. 2015 Jun;5(6):636-51. doi: 10.1158/2159-8290.CD-14-1113. Epub 2015 Mar 31.

38.

TGF-β/Smad signaling through DOCK4 facilitates lung adenocarcinoma metastasis.

Yu JR, Tai Y, Jin Y, Hammell MC, Wilkinson JE, Roe JS, Vakoc CR, Van Aelst L.

Genes Dev. 2015 Feb 1;29(3):250-61. doi: 10.1101/gad.248963.114.

39.

ATDC induces an invasive switch in KRAS-induced pancreatic tumorigenesis.

Wang L, Yang H, Abel EV, Ney GM, Palmbos PL, Bednar F, Zhang Y, Leflein J, Waghray M, Owens S, Wilkinson JE, Prasad J, Ljungman M, Rhim AD, Pasca di Magliano M, Simeone DM.

Genes Dev. 2015 Jan 15;29(2):171-83. doi: 10.1101/gad.253591.114.

40.

The perceived effects of faculty presence vs. absence on small-group learning and group dynamics: a quasi-experimental study.

Hoffman M, Wilkinson JE, Xu J, Wiecha J.

BMC Med Educ. 2014 Dec 10;14:258. doi: 10.1186/s12909-014-0258-1.

41.

Proinflammatory effects of interferon gamma in mouse adenovirus 1 myocarditis.

McCarthy MK, Procario MC, Twisselmann N, Wilkinson JE, Archambeau AJ, Michele DE, Day SM, Weinberg JB.

J Virol. 2015 Jan;89(1):468-79. doi: 10.1128/JVI.02077-14. Epub 2014 Oct 15.

42.

Inducible in vivo silencing of Brd4 identifies potential toxicities of sustained BET protein inhibition.

Bolden JE, Tasdemir N, Dow LE, van Es JH, Wilkinson JE, Zhao Z, Clevers H, Lowe SW.

Cell Rep. 2014 Sep 25;8(6):1919-1929. doi: 10.1016/j.celrep.2014.08.025. Epub 2014 Sep 18.

43.

Resident alveolar macrophages suppress, whereas recruited monocytes promote, allergic lung inflammation in murine models of asthma.

Zasłona Z, Przybranowski S, Wilke C, van Rooijen N, Teitz-Tennenbaum S, Osterholzer JJ, Wilkinson JE, Moore BB, Peters-Golden M.

J Immunol. 2014 Oct 15;193(8):4245-53. doi: 10.4049/jimmunol.1400580. Epub 2014 Sep 15.

44.

Acquired dependence of acute myeloid leukemia on the DEAD-box RNA helicase DDX5.

Mazurek A, Park Y, Miething C, Wilkinson JE, Gillis J, Lowe SW, Vakoc CR, Stillman B.

Cell Rep. 2014 Jun 26;7(6):1887-99. doi: 10.1016/j.celrep.2014.05.019. Epub 2014 Jun 5.

45.

A positive feedback between p53 and miR-34 miRNAs mediates tumor suppression.

Okada N, Lin CP, Ribeiro MC, Biton A, Lai G, He X, Bu P, Vogel H, Jablons DM, Keller AC, Wilkinson JE, He B, Speed TP, He L.

Genes Dev. 2014 Mar 1;28(5):438-50. doi: 10.1101/gad.233585.113. Epub 2014 Feb 14.

46.

RapidCaP, a novel GEM model for metastatic prostate cancer analysis and therapy, reveals myc as a driver of Pten-mutant metastasis.

Cho H, Herzka T, Zheng W, Qi J, Wilkinson JE, Bradner JE, Robinson BD, Castillo-Martin M, Cordon-Cardo C, Trotman LC.

Cancer Discov. 2014 Mar;4(3):318-33. doi: 10.1158/2159-8290.CD-13-0346. Epub 2014 Jan 20.

47.

Splicing factor SRSF6 promotes hyperplasia of sensitized skin.

Jensen MA, Wilkinson JE, Krainer AR.

Nat Struct Mol Biol. 2014 Feb;21(2):189-97. doi: 10.1038/nsmb.2756. Epub 2014 Jan 19.

48.

Acarbose, 17-α-estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males.

Harrison DE, Strong R, Allison DB, Ames BN, Astle CM, Atamna H, Fernandez E, Flurkey K, Javors MA, Nadon NL, Nelson JF, Pletcher S, Simpkins JW, Smith D, Wilkinson JE, Miller RA.

Aging Cell. 2014 Apr;13(2):273-82. doi: 10.1111/acel.12170. Epub 2013 Nov 19.

49.

Transcription factors OVOL1 and OVOL2 induce the mesenchymal to epithelial transition in human cancer.

Roca H, Hernandez J, Weidner S, McEachin RC, Fuller D, Sud S, Schumann T, Wilkinson JE, Zaslavsky A, Li H, Maher CA, Daignault-Newton S, Healy PN, Pienta KJ.

PLoS One. 2013 Oct 4;8(10):e76773. doi: 10.1371/journal.pone.0076773. eCollection 2013.

50.

Cold pleasure. Why we like ice drinks, ice-lollies and ice cream.

Eccles R, Du-Plessis L, Dommels Y, Wilkinson JE.

Appetite. 2013 Dec;71:357-60. doi: 10.1016/j.appet.2013.09.011. Epub 2013 Sep 21. Review.

PMID:
24060271

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