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Biomarkers of cardiovascular risk across phenotypes of osteoarthritis.

Provan SA, Rollefstad S, Ikdahl E, Mathiessen A, Berg IJ, Eeg I, Wilkinson IB, McEniery CM, Kvien TK, Hammer HB, Østerås N, Haugen IK, Semb AG.

BMC Rheumatol. 2019 Aug 8;3:33. doi: 10.1186/s41927-019-0081-8. eCollection 2019.


Does Poorer Pulmonary Function Accelerate Arterial Stiffening?: A Cohort Study With Repeated Measurements of Carotid-Femoral Pulse Wave Velocity.

Okamoto M, Shipley MJ, Wilkinson IB, McEniery CM, Valencia-Hernández CA, Singh-Manoux A, Kivimaki M, Brunner EJ.

Hypertension. 2019 Oct;74(4):929-935. doi: 10.1161/HYPERTENSIONAHA.119.13183. Epub 2019 Aug 5.


Letter by Mäki-Petäjä et al Regarding Article "Elevated Muscle Sympathetic Nerve Activity Contributes to Central Artery Stiffness in Young and Middle-Age/Older Adults".

Mäki-Petäjä KM, Wilkinson IB, Nichols WW.

Hypertension. 2019 Aug;74(2):e31-e32. doi: 10.1161/HYPERTENSIONAHA.119.13292. Epub 2019 Jun 24. No abstract available.


Lumbosacral Radiculopathy: Inciting Events and Their Association with Epidural Steroid Injection Outcomes.

Engle AM, Chen Y, Marascalchi B, Wilkinson I, Abrams WB, He C, Yao AL, Adekoya P, Cohen ZO, Cohen SP.

Pain Med. 2019 May 17. pii: pnz097. doi: 10.1093/pm/pnz097. [Epub ahead of print]


Altered frontal and insular functional connectivity as pivotal mechanisms for apathy in Alzheimer's disease.

Jones SA, De Marco M, Manca R, Bell SM, Blackburn DJ, Wilkinson ID, Soininen H, Venneri A.

Cortex. 2019 Apr 20;119:100-110. doi: 10.1016/j.cortex.2019.04.008. [Epub ahead of print]


Painful and Painless Diabetic Neuropathies: What Is the Difference?

Shillo P, Sloan G, Greig M, Hunt L, Selvarajah D, Elliott J, Gandhi R, Wilkinson ID, Tesfaye S.

Curr Diab Rep. 2019 May 7;19(6):32. doi: 10.1007/s11892-019-1150-5. Review.


Biomarkers in Motor Neuron Disease: A State of the Art Review.

Verber NS, Shepheard SR, Sassani M, McDonough HE, Moore SA, Alix JJP, Wilkinson ID, Jenkins TM, Shaw PJ.

Front Neurol. 2019 Apr 3;10:291. doi: 10.3389/fneur.2019.00291. eCollection 2019. Review.


Dex-CSDH randomised, placebo-controlled trial of dexamethasone for chronic subdural haematoma: report of the internal pilot phase.

Edlmann E, Thelin EP, Caldwell K, Turner C, Whitfield P, Bulters D, Holton P, Suttner N, Owusu-Agyemang K, Al-Tamimi YZ, Gatt D, Thomson S, Anderson IA, Richards O, Gherle M, Toman E, Nandi D, Kane P, Pantaleo B, Davis-Wilkie C, Tarantino S, Barton G, Marcus HJ, Chari A, Belli A, Bond S, Gafoor R, Dawson S, Whitehead L, Brennan P, Wilkinson I, Kolias AG, Hutchinson PJA; Dex-CSDH trial collaborative and BNTRC collaborative.

Sci Rep. 2019 Apr 10;9(1):5885. doi: 10.1038/s41598-019-42087-z.


Correction to: Dexamethasone for adult patients with a symptomatic chronic subdural haematoma (Dex-CSDH) trial: study protocol for a randomised controlled trial.

Kolias AG, Edlmann E, Thelin EP, Bulters D, Holton P, Suttner N, Owusu-Agyemang K, Al-Tamimi YZ, Gatt D, Thomson S, Anderson IA, Richards O, Whitfield P, Gherle M, Caldwell K, Davis-Wilkie C, Tarantino S, Barton G, Marcus HJ, Chari A, Brennan P, Belli A, Bond S, Turner C, Whitehead L, Wilkinson I, Hutchinson PJ; British Neurosurgical Trainee Research Collaborative (BNTRC) and Dex-CSDH Trial Collaborators.

Trials. 2019 Mar 18;20(1):175. doi: 10.1186/s13063-019-3283-x.


Big GABA II: Water-referenced edited MR spectroscopy at 25 research sites.

Mikkelsen M, Rimbault DL, Barker PB, Bhattacharyya PK, Brix MK, Buur PF, Cecil KM, Chan KL, Chen DY, Craven AR, Cuypers K, Dacko M, Duncan NW, Dydak U, Edmondson DA, Ende G, Ersland L, Forbes MA, Gao F, Greenhouse I, Harris AD, He N, Heba S, Hoggard N, Hsu TW, Jansen JFA, Kangarlu A, Lange T, Lebel RM, Li Y, Lin CE, Liou JK, Lirng JF, Liu F, Long JR, Ma R, Maes C, Moreno-Ortega M, Murray SO, Noah S, Noeske R, Noseworthy MD, Oeltzschner G, Porges EC, Prisciandaro JJ, Puts NAJ, Roberts TPL, Sack M, Sailasuta N, Saleh MG, Schallmo MP, Simard N, Stoffers D, Swinnen SP, Tegenthoff M, Truong P, Wang G, Wilkinson ID, Wittsack HJ, Woods AJ, Xu H, Yan F, Zhang C, Zipunnikov V, Zöllner HJ, Edden RAE.

Neuroimage. 2019 May 1;191:537-548. doi: 10.1016/j.neuroimage.2019.02.059. Epub 2019 Mar 3.


Do water's electrons care about electrolytes?

Pohl MN, Muchová E, Seidel R, Ali H, Sršeň Š, Wilkinson I, Winter B, Slavíček P.

Chem Sci. 2018 Nov 1;10(3):848-865. doi: 10.1039/c8sc03381a. eCollection 2019 Jan 21.


Cardiovascular Phenotype of Elevated Blood Pressure Differs Markedly Between Young Males and Females: The Enigma Study

Nardin C, Maki-Petaja KM, Miles KL, Yasmin, McDonnell BJ, Cockcroft JR, Wilkinson IB, McEniery CM; Enigma Study Investigators.

Hypertension. 2018 Dec;72(6):1277-1284. doi: 10.1161/HYPERTENSIONAHA.118.11975. Epub 2018 Oct 15.


Methods and considerations concerning cardiac output measurement in pregnant women: recommendations of the International Working Group on Maternal Hemodynamics.

Bijl RC, Valensise H, Novelli GP, Vasapollo B, Wilkinson I, Thilaganathan B, Stöhr EJ, Lees C, van der Marel CD, Cornette JMJ; International Working Group on Maternal Hemodynamics.

Ultrasound Obstet Gynecol. 2019 Jul;54(1):35-50. doi: 10.1002/uog.20231.


Stiffening and ventricular-arterial interaction in the ascending aorta using MRI: ageing effects in healthy humans.

Li Y, Hickson SS, McEniery CM, Wilkinson IB, Khir AW.

J Hypertens. 2019 Feb;37(2):347-355. doi: 10.1097/HJH.0000000000001886.


Quantifying normal human brain metabolism using hyperpolarized [1-13C]pyruvate and magnetic resonance imaging.

Grist JT, McLean MA, Riemer F, Schulte RF, Deen SS, Zaccagna F, Woitek R, Daniels CJ, Kaggie JD, Matys T, Patterson I, Slough R, Gill AB, Chhabra A, Eichenberger R, Laurent MC, Comment A, Gillard JH, Coles AJ, Tyler DJ, Wilkinson I, Basu B, Lomas DJ, Graves MJ, Brindle KM, Gallagher FA.

Neuroimage. 2019 Apr 1;189:171-179. doi: 10.1016/j.neuroimage.2019.01.027. Epub 2019 Jan 11.


Structural and Functional Abnormalities of the Primary Somatosensory Cortex in Diabetic Peripheral Neuropathy: A Multimodal MRI Study.

Selvarajah D, Wilkinson ID, Fang F, Sankar A, Davies J, Boland E, Harding J, Rao G, Gandhi R, Tracey I, Tesfaye S.

Diabetes. 2019 Apr;68(4):796-806. doi: 10.2337/db18-0509. Epub 2019 Jan 7.


Biomarkers and clinical outcomes in COPD: a systematic review and meta-analysis.

Fermont JM, Masconi KL, Jensen MT, Ferrari R, Di Lorenzo VAP, Marott JM, Schuetz P, Watz H, Waschki B, Müllerova H, Polkey MI, Wilkinson IB, Wood AM.

Thorax. 2019 May;74(5):439-446. doi: 10.1136/thoraxjnl-2018-211855. Epub 2019 Jan 7.


Different Effects of Vascular Aging on Ischemic Predisposition in Healthy Men and Women.

Namasivayam M, McEniery CM, Wilkinson IB, Yasmin, Cockroft JR, McDonnell BJ, Adji A, O'Rourke MF.

Hypertension. 2018 Dec;72(6):1294-1300. doi: 10.1161/HYPERTENSIONAHA.118.11642.


Evaluation of inert gas rebreathing for determination of cardiac output: influence of age, gender and body size.

Middlemiss JE, Cocks A, Paapstel K, Maki-Petaja KM, Sunita, Wilkinson IB, McEniery CM; ACCT Study Investigators.

Hypertens Res. 2019 Jun;42(6):834-844. doi: 10.1038/s41440-018-0179-1. Epub 2018 Dec 18.


Backward in Coming Forward.

Mäki-Petäjä KM, Wilkinson IB.

Am J Hypertens. 2019 Feb 12;32(3):240-241. doi: 10.1093/ajh/hpy188. No abstract available.


Dexamethasone for adult patients with a symptomatic chronic subdural haematoma (Dex-CSDH) trial: study protocol for a randomised controlled trial.

Kolias AG, Edlmann E, Thelin EP, Bulters D, Holton P, Suttner N, Owusu-Agyemang K, Al-Tamimi YZ, Gatt D, Thomson S, Anderson IA, Richards O, Whitfield P, Gherle M, Caldwell K, Davis-Wilkie C, Tarantino S, Barton G, Marcus HJ, Chari A, Brennan P, Belli A, Bond S, Turner C, Whitehead L, Wilkinson I, Hutchinson PJ; British Neurosurgical Trainee Research Collaborative (BNTRC) and Dex-CSDH Trial Collaborators.

Trials. 2018 Dec 4;19(1):670. doi: 10.1186/s13063-018-3050-4. Erratum in: Trials. 2019 Mar 18;20(1):175. Zolnouria, Ardalan [corrected to Zolnourian, Ardalan].


Cardiac output changes from prior to pregnancy to post partum using two non-invasive techniques.

Masini G, Foo LF, Cornette J, Tay J, Rizopoulos D, McEniery CM, Wilkinson IB, Lees CC.

Heart. 2019 May;105(9):715-720. doi: 10.1136/heartjnl-2018-313682. Epub 2018 Oct 30.


Evaluation of the Omron HEM-907 automated blood pressure device: comparison with office and ambulatory blood pressure readings.

D'Sa L, Senaratne N, Woodcock-Smith J, Miles KM, Wilkinson IB, McEniery CM.

Hypertens Res. 2019 Jan;42(1):52-58. doi: 10.1038/s41440-018-0120-7. Epub 2018 Oct 30.


Vacuum ultraviolet excited state dynamics of the smallest ring, cyclopropane. II. Time-resolved photoelectron spectroscopy and ab initio dynamics.

Coates MR, Larsen MAB, Forbes R, Neville SP, Boguslavskiy AE, Wilkinson I, Sølling TI, Lausten R, Stolow A, Schuurman MS.

J Chem Phys. 2018 Oct 14;149(14):144311. doi: 10.1063/1.5044402.


Uterine and fetal placental Doppler indices are associated with maternal cardiovascular function.

Tay J, Masini G, McEniery CM, Giussani DA, Shaw CJ, Wilkinson IB, Bennett PR, Lees CC.

Am J Obstet Gynecol. 2019 Jan;220(1):96.e1-96.e8. doi: 10.1016/j.ajog.2018.09.017. Epub 2018 Sep 19.


Skin Sodium and Hypertension: a Paradigm Shift?

Selvarajah V, Connolly K, McEniery C, Wilkinson I.

Curr Hypertens Rep. 2018 Sep 13;20(11):94. doi: 10.1007/s11906-018-0892-9. Review.


A new look at painful diabetic neuropathy.

Sloan G, Shillo P, Selvarajah D, Wu J, Wilkinson ID, Tracey I, Anand P, Tesfaye S.

Diabetes Res Clin Pract. 2018 Oct;144:177-191. doi: 10.1016/j.diabres.2018.08.020. Epub 2018 Sep 7. Review.


Reduced vitamin D levels in painful diabetic peripheral neuropathy.

Shillo P, Selvarajah D, Greig M, Gandhi R, Rao G, Wilkinson ID, Anand P, Tesfaye S.

Diabet Med. 2019 Jan;36(1):44-51. doi: 10.1111/dme.13798. Epub 2018 Sep 20.


A randomized controlled crossover trial evaluating differential responses to antihypertensive drugs (used as mono- or dual therapy) on the basis of ethnicity: The comparIsoN oF Optimal Hypertension RegiMens; part of the Ancestry Informative Markers in HYpertension program-AIM-HY INFORM trial.

Mukhtar O, Cheriyan J, Cockcroft JR, Collier D, Coulson JM, Dasgupta I, Faconti L, Glover M, Heagerty AM, Khong TK, Lip GYH, Mander AP, Marchong MN, Martin U, McDonnell BJ, McEniery CM, Padmanabhan S, Saxena M, Sever PJ, Shiel JI, Wych J, Chowienczyk PJ, Wilkinson IB.

Am Heart J. 2018 Oct;204:102-108. doi: 10.1016/j.ahj.2018.05.006. Epub 2018 May 20.


Functional characterization of common BCL11B gene desert variants suggests a lymphocyte-mediated association of BCL11B with aortic stiffness.

Maskari RA, Hardege I, Cleary S, Figg N, Li Y, Siew K, Khir A, Yu Y, Liu P, Wilkinson I, O'Shaughnessy K, Yasmin.

Eur J Hum Genet. 2018 Nov;26(11):1648-1657. doi: 10.1038/s41431-018-0226-z. Epub 2018 Aug 8.



Lees C, Tay J, Wilkinson I.

Am J Obstet Gynecol. 2018 Dec;219(6):627-628. doi: 10.1016/j.ajog.2018.07.027. Epub 2018 Aug 4. No abstract available.


A Pilot Study Investigating a Novel Non-Linear Measure of Eyes Open versus Eyes Closed EEG Synchronization in People with Alzheimer’s Disease and Healthy Controls

Blackburn DJ, Zhao Y, De Marco M, Bell SM, He F, Wei HL, Lawrence S, Unwin ZC, Blyth M, Angel J, Baster K, Farrow TFD, Wilkinson ID, Billings SA, Venneri A, Sarrigiannis PG.

Brain Sci. 2018 Jul 17;8(7). pii: E134. doi: 10.3390/brainsci8070134.


Inverting the patient involvement paradigm: defining patient led research.

Mader LB, Harris T, Kläger S, Wilkinson IB, Hiemstra TF.

Res Involv Engagem. 2018 Jul 10;4:21. doi: 10.1186/s40900-018-0104-4. eCollection 2018.


Association Between Prepregnancy Cardiovascular Function and Subsequent Preeclampsia or Fetal Growth Restriction.

Foo FL, Mahendru AA, Masini G, Fraser A, Cacciatore S, MacIntyre DA, McEniery CM, Wilkinson IB, Bennett PR, Lees CC.

Hypertension. 2018 Aug;72(2):442-450. doi: 10.1161/HYPERTENSIONAHA.118.11092. Epub 2018 Jul 2.


Motion artifacts in standard clinical setting obscure disease-specific differences in quantitative susceptibility mapping.

Meineke J, Wenzel F, De Marco M, Venneri A, Blackburn DJ, Teh K, Wilkinson ID, Katscher U.

Phys Med Biol. 2018 Jul 9;63(14):14NT01. doi: 10.1088/1361-6560/aacc52.


The matrix proteins aggrecan and fibulin-1 play a key role in determining aortic stiffness.

Yasmin, Maskari RA, McEniery CM, Cleary SE, Li Y, Siew K, Figg NL, Khir AW, Cockcroft JR, Wilkinson IB, O'Shaughnessy KM.

Sci Rep. 2018 Jun 4;8(1):8550. doi: 10.1038/s41598-018-25851-5.


Vascular inflammation and aortic stiffness: potential mechanisms of increased vascular risk in chronic obstructive pulmonary disease.

Fisk M, Cheriyan J, Mohan D, McEniery CM, Forman J, Cockcroft JR, Rudd JHF, Tal-Singer R, Hopkinson NS, Polkey MI, Wilkinson IB.

Respir Res. 2018 May 24;19(1):100. doi: 10.1186/s12931-018-0792-1.


Randomised controlled trial of high versus ad libitum water intake in patients with autosomal dominant polycystic kidney disease: rationale and design of the DRINK feasibility trial.

El-Damanawi R, Lee M, Harris T, Mader LB, Bond S, Pavey H, Sandford RN, Wilkinson IB, Burrows A, Woznowski P, Ben-Shlomo Y, Karet Frankl FE, Hiemstra TF.

BMJ Open. 2018 May 9;8(5):e022859. doi: 10.1136/bmjopen-2018-022859.


About That Sex-Related Stiffening.

Mäki-Petäjä KM, Wilkinson IB.

Am J Hypertens. 2018 Jun 11;31(7):770-771. doi: 10.1093/ajh/hpy072. No abstract available.


Brain connectivity and cognitive processing speed in multiple sclerosis: A systematic review.

Manca R, Sharrack B, Paling D, Wilkinson ID, Venneri A.

J Neurol Sci. 2018 May 15;388:115-127. doi: 10.1016/j.jns.2018.03.003. Epub 2018 Mar 2.


Fibrinogen does not relate to cardiovascular or muscle manifestations in COPD: cross-sectional data from the ERICA study.

Mohan D, Forman JR, Allinder M, McEniery CM, Bolton CE, Cockcroft JR, MacNee W, Fuld J, Marchong M, Gale NS, Fisk M, Nagarajan S, Cheriyan J, Lomas DA, Calverley PMA, Miller BE, Tal-Singer R, Wilkinson IB, Polkey MI; ERICA Consortium.

Thorax. 2018 Dec;73(12):1182-1185. doi: 10.1136/thoraxjnl-2018-211556. Epub 2018 Apr 4.


Isolated systolic hypertension in the young: a position paper endorsed by the European Society of Hypertension.

Palatini P, Rosei EA, Avolio A, Bilo G, Casiglia E, Ghiadoni L, Giannattasio C, Grassi G, Jelakovich B, Julius S, Mancia G, McEniery CM, O'Rourke MF, Parati G, Pauletto P, Pucci G, Saladini F, Strazzullo P, Tsioufis K, Wilkinson IB, Zanchetti A.

J Hypertens. 2018 Jun;36(6):1222-1236. doi: 10.1097/HJH.0000000000001726. Review. Erratum in: J Hypertens. 2018 Oct;36(10):2120.


The p38 mitogen activated protein kinase inhibitor losmapimod in chronic obstructive pulmonary disease patients with systemic inflammation, stratified by fibrinogen: A randomised double-blind placebo-controlled trial.

Fisk M, Cheriyan J, Mohan D, Forman J, Mäki-Petäjä KM, McEniery CM, Fuld J, Rudd JHF, Hopkinson NS, Lomas DA, Cockcroft JR, Tal-Singer R, Polkey MI, Wilkinson IB.

PLoS One. 2018 Mar 22;13(3):e0194197. doi: 10.1371/journal.pone.0194197. eCollection 2018.


Development and Validation of a Path Length Calculation for Carotid-Femoral Pulse Wave Velocity Measurement: A TASCFORCE, SUMMIT, and Caerphilly Collaborative Venture.

Weir-McCall JR, Brown L, Summersgill J, Talarczyk P, Bonnici-Mallia M, Chin SC, Khan F, Struthers AD, Sullivan F, Colhoun HM, Shore AC, Aizawa K, Groop L, Nilsson J, Cockcroft JR, McEniery CM, Wilkinson IB, Ben-Shlomo Y, Houston JG.

Hypertension. 2018 May;71(5):937-945. doi: 10.1161/HYPERTENSIONAHA.117.10620. Epub 2018 Mar 19.


When monoclonal antibodies are not monospecific: Hybridomas frequently express additional functional variable regions.

Bradbury ARM, Trinklein ND, Thie H, Wilkinson IC, Tandon AK, Anderson S, Bladen CL, Jones B, Aldred SF, Bestagno M, Burrone O, Maynard J, Ferrara F, Trimmer JS, Görnemann J, Glanville J, Wolf P, Frenzel A, Wong J, Koh XY, Eng HY, Lane D, Lefranc MP, Clark M, Dübel S.

MAbs. 2018 May/Jun;10(4):539-546. doi: 10.1080/19420862.2018.1445456. Epub 2018 Mar 29.


Early and late preeclampsia are characterized by high cardiac output, but in the presence of fetal growth restriction, cardiac output is low: insights from a prospective study.

Tay J, Foo L, Masini G, Bennett PR, McEniery CM, Wilkinson IB, Lees CC.

Am J Obstet Gynecol. 2018 May;218(5):517.e1-517.e12. doi: 10.1016/j.ajog.2018.02.007. Epub 2018 Feb 21.


Surrogate Markers of Cardiovascular Risk and Chronic Obstructive Pulmonary Disease: A Large Case-Controlled Study.

Fisk M, McEniery CM, Gale N, Mäki-Petäjä K, Forman JR, Munnery M, Woodcock-Smith J, Cheriyan J, Mohan D, Fuld J, Tal-Singer R, Polkey MI, Cockcroft JR, Wilkinson IB; ERICA Consortium and ACCT Investigators.

Hypertension. 2018 Mar;71(3):499-506. doi: 10.1161/HYPERTENSIONAHA.117.10151. Epub 2018 Jan 22. Erratum in: Hypertension. 2018 Sep;72(3):e30.


Longitudinal Diffusion-Weighted Whole-Body MRI Demonstrates Dynamic Changes in Muscle Integrity in Motor Neuron Disease.

Pierry IA, Alix J, Rao DG, Hoggard N, Bigley J, McDermott CJ, Wilkinson ID, Shaw PJ, Jenkins TM.

J Neuromuscul Dis. 2018;5(1):107. doi: 10.3233/JND-179002. No abstract available.


The Rationale and Design of the Reducing Pathology in Alzheimer's Disease through Angiotensin TaRgeting (RADAR) Trial.

Kehoe PG, Blair PS, Howden B, Thomas DL, Malone IB, Horwood J, Clement C, Selman LE, Baber H, Lane A, Coulthard E, Passmore AP, Fox NC, Wilkinson IB, Ben-Shlomo Y.

J Alzheimers Dis. 2018;61(2):803-814. doi: 10.3233/JAD-170101.


Frequency and phase correction for multiplexed edited MRS of GABA and glutathione.

Mikkelsen M, Saleh MG, Near J, Chan KL, Gong T, Harris AD, Oeltzschner G, Puts NAJ, Cecil KM, Wilkinson ID, Edden RAE.

Magn Reson Med. 2018 Jul;80(1):21-28. doi: 10.1002/mrm.27027. Epub 2017 Dec 7.

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