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Items: 1 to 50 of 134


The evolutionary history of Ephs and ephrins: towards multicellular organisms.

Arcas A, Wilkinson DG, Nieto MÁ.

Mol Biol Evol. 2019 Oct 7. pii: msz222. doi: 10.1093/molbev/msz222. [Epub ahead of print]


Actomyosin regulation by Eph receptor signaling couples boundary cell formation to border sharpness.

Cayuso J, Xu Q, Addison M, Wilkinson DG.

Elife. 2019 Sep 10;8. pii: e49696. doi: 10.7554/eLife.49696.


Role of forward and reverse signaling in Eph receptor and ephrin mediated cell segregation.

Wu Z, Ashlin TG, Xu Q, Wilkinson DG.

Exp Cell Res. 2019 Aug 1;381(1):57-65. doi: 10.1016/j.yexcr.2019.04.040. Epub 2019 May 7.


Establishing sharp and homogeneous segments in the hindbrain.

Wilkinson DG.

F1000Res. 2018 Aug 13;7. pii: F1000 Faculty Rev-1268. doi: 10.12688/f1000research.15391.1. eCollection 2018. Review.


Cell Identity Switching Regulated by Retinoic Acid Signaling Maintains Homogeneous Segments in the Hindbrain.

Addison M, Xu Q, Cayuso J, Wilkinson DG.

Dev Cell. 2018 Jun 4;45(5):606-620.e3. doi: 10.1016/j.devcel.2018.04.003. Epub 2018 May 3.


Cell segregation and border sharpening by Eph receptor-ephrin-mediated heterotypic repulsion.

Taylor HB, Khuong A, Wu Z, Xu Q, Morley R, Gregory L, Poliakov A, Taylor WR, Wilkinson DG.

J R Soc Interface. 2017 Jul;14(132). pii: 20170338. doi: 10.1098/rsif.2017.0338.


Segment Identity and Cell Segregation in the Vertebrate Hindbrain.

Addison M, Wilkinson DG.

Curr Top Dev Biol. 2016;117:581-96. doi: 10.1016/bs.ctdb.2015.10.019. Epub 2016 Jan 7. Review.


Balancing cell behavior at boundaries.

Wilkinson DG.

J Cell Biol. 2015 Mar 16;208(6):659-60. doi: 10.1083/jcb.201501107. Review.


Regulation of cell differentiation by Eph receptor and ephrin signaling.

Wilkinson DG.

Cell Adh Migr. 2014;8(4):339-48. doi: 10.4161/19336918.2014.970007. Review. Erratum in: Cell Adh Migr. 2015;9(1-2):166.


Mechanisms of boundary formation by Eph receptor and ephrin signaling.

Cayuso J, Xu Q, Wilkinson DG.

Dev Biol. 2015 May 1;401(1):122-31. doi: 10.1016/j.ydbio.2014.11.013. Epub 2014 Nov 20. Review.


Valproic acid silencing of ascl1b/Ascl1 results in the failure of serotonergic differentiation in a zebrafish model of fetal valproate syndrome.

Jacob J, Ribes V, Moore S, Constable SC, Sasai N, Gerety SS, Martin DJ, Sergeant CP, Wilkinson DG, Briscoe J.

Dis Model Mech. 2014 Jan;7(1):107-17. doi: 10.1242/dmm.013219. Epub 2013 Oct 17.


A Hox gene controls lateral line cell migration by regulating chemokine receptor expression downstream of Wnt signaling.

Breau MA, Wilkinson DG, Xu Q.

Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):16892-7. doi: 10.1073/pnas.1306282110. Epub 2013 Sep 30. Erratum in: Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):19651.


Boundary formation in the development of the vertebrate hindbrain.

Xu Q, Wilkinson DG.

Wiley Interdiscip Rev Dev Biol. 2013 Sep-Oct;2(5):735-45. doi: 10.1002/wdev.106. Epub 2013 Jan 25. Review.


An inducible transgene expression system for zebrafish and chick.

Gerety SS, Breau MA, Sasai N, Xu Q, Briscoe J, Wilkinson DG.

Development. 2013 May;140(10):2235-43. doi: 10.1242/dev.091520.


Retinoid acid specifies neuronal identity through graded expression of Ascl1.

Jacob J, Kong J, Moore S, Milton C, Sasai N, Gonzalez-Quevedo R, Terriente J, Imayoshi I, Kageyama R, Wilkinson DG, Novitch BG, Briscoe J.

Curr Biol. 2013 Mar 4;23(5):412-8. doi: 10.1016/j.cub.2013.01.046. Epub 2013 Feb 14. Erratum in: Curr Biol. 2013 Apr 8;23(7):632. Kageyama, Ryoichoro [corrected to Kageyama, Ryoichiro].


A mechanical model of cell segregation driven by differential adhesion.

Taylor WR, Morley R, Krasavin A, Gregory L, Wilkinson DG, Poliakov A.

PLoS One. 2012;7(8):e43226. doi: 10.1371/journal.pone.0043226. Epub 2012 Aug 29.


Signalling from hindbrain boundaries regulates neuronal clustering that patterns neurogenesis.

Terriente J, Gerety SS, Watanabe-Asaka T, Gonzalez-Quevedo R, Wilkinson DG.

Development. 2012 Aug;139(16):2978-87. doi: 10.1242/dev.080135. Epub 2012 Jul 4.


Chemokine and Fgf signalling act as opposing guidance cues in formation of the lateral line primordium.

Breau MA, Wilson D, Wilkinson DG, Xu Q.

Development. 2012 Jun;139(12):2246-53. doi: 10.1242/dev.080275.


Molecular mechanisms of cell segregation and boundary formation in development and tumorigenesis.

Batlle E, Wilkinson DG.

Cold Spring Harb Perspect Biol. 2012 Jan 1;4(1):a008227. doi: 10.1101/cshperspect.a008227. Review.


Morpholino artifacts provide pitfalls and reveal a novel role for pro-apoptotic genes in hindbrain boundary development.

Gerety SS, Wilkinson DG.

Dev Biol. 2011 Feb 15;350(2):279-89. doi: 10.1016/j.ydbio.2010.11.030. Epub 2010 Dec 8.


EphB-ephrin-B2 interactions are required for thymus migration during organogenesis.

Foster KE, Gordon J, Cardenas K, Veiga-Fernandes H, Makinen T, Grigorieva E, Wilkinson DG, Blackburn CC, Richie E, Manley NR, Adams RH, Kioussis D, Coles MC.

Proc Natl Acad Sci U S A. 2010 Jul 27;107(30):13414-9. doi: 10.1073/pnas.1003747107. Epub 2010 Jul 8.


Neuronal regulation of the spatial patterning of neurogenesis.

Gonzalez-Quevedo R, Lee Y, Poss KD, Wilkinson DG.

Dev Cell. 2010 Jan 19;18(1):136-47. doi: 10.1016/j.devcel.2009.11.010.


A feedback loop mediated by degradation of an inhibitor is required to initiate neuronal differentiation.

Sobieszczuk DF, Poliakov A, Xu Q, Wilkinson DG.

Genes Dev. 2010 Jan 15;24(2):206-18. doi: 10.1101/gad.554510.


Cell-specific information processing in segregating populations of Eph receptor ephrin-expressing cells.

Jørgensen C, Sherman A, Chen GI, Pasculescu A, Poliakov A, Hsiung M, Larsen B, Wilkinson DG, Linding R, Pawson T.

Science. 2009 Dec 11;326(5959):1502-9. doi: 10.1126/science.1176615.


Lunatic fringe promotes the lateral inhibition of neurogenesis.

Nikolaou N, Watanabe-Asaka T, Gerety S, Distel M, Köster RW, Wilkinson DG.

Development. 2009 Aug;136(15):2523-33. doi: 10.1242/dev.034736. Epub 2009 Jun 24.


Boundary cells regulate a switch in the expression of FGF3 in hindbrain rhombomeres.

Sela-Donenfeld D, Kayam G, Wilkinson DG.

BMC Dev Biol. 2009 Feb 20;9:16. doi: 10.1186/1471-213X-9-16.


Regulation of EphB2 activation and cell repulsion by feedback control of the MAPK pathway.

Poliakov A, Cotrina ML, Pasini A, Wilkinson DG.

J Cell Biol. 2008 Dec 1;183(5):933-47. doi: 10.1083/jcb.200807151.


Inhibition of BMPs by follistatin is required for FGF3 expression and segmental patterning of the hindbrain.

Weisinger K, Wilkinson DG, Sela-Donenfeld D.

Dev Biol. 2008 Dec 15;324(2):213-25. doi: 10.1016/j.ydbio.2008.09.005. Epub 2008 Sep 18.


In situ hybridization analysis of chick embryos in whole-mount and tissue sections.

Acloque H, Wilkinson DG, Nieto MA.

Methods Cell Biol. 2008;87:169-85. doi: 10.1016/S0091-679X(08)00209-4. Review. No abstract available.


Minimum information specification for in situ hybridization and immunohistochemistry experiments (MISFISHIE).

Deutsch EW, Ball CA, Berman JJ, Bova GS, Brazma A, Bumgarner RE, Campbell D, Causton HC, Christiansen JH, Daian F, Dauga D, Davidson DR, Gimenez G, Goo YA, Grimmond S, Henrich T, Herrmann BG, Johnson MH, Korb M, Mills JC, Oudes AJ, Parkinson HE, Pascal LE, Pollet N, Quackenbush J, Ramialison M, Ringwald M, Salgado D, Sansone SA, Sherlock G, Stoeckert CJ Jr, Swedlow J, Taylor RC, Walashek L, Warford A, Wilkinson DG, Zhou Y, Zon LI, Liu AY, True LD.

Nat Biotechnol. 2008 Mar;26(3):305-12. doi: 10.1038/nbt1391.


T-cadherin suppresses angiogenesis in vivo by inhibiting migration of endothelial cells.

Rubina K, Kalinina N, Potekhina A, Efimenko A, Semina E, Poliakov A, Wilkinson DG, Parfyonova Y, Tkachuk V.

Angiogenesis. 2007;10(3):183-95. Epub 2007 May 8.


Ephrins make eyes with planar cell polarity.

Poliakov A, Wilkinson DG.

Nat Cell Biol. 2006 Jan;8(1):7-8. No abstract available.


Donepezil in vascular dementia: combined analysis of two large-scale clinical trials.

Román GC, Wilkinson DG, Doody RS, Black SE, Salloway SP, Schindler RJ.

Dement Geriatr Cogn Disord. 2005;20(6):338-44. Epub 2005 Sep 23.


Switching from donepezil to galantamine: a double-blind study of two wash-out periods.

Wilkinson DG, Howe I.

Int J Geriatr Psychiatry. 2005 May;20(5):489-91. No abstract available.


Eph receptors: two ways to sharpen boundaries.

Sela-Donenfeld D, Wilkinson DG.

Curr Biol. 2005 Mar 29;15(6):R210-2. Review.


Wnt1 regulates neurogenesis and mediates lateral inhibition of boundary cell specification in the zebrafish hindbrain.

Amoyel M, Cheng YC, Jiang YJ, Wilkinson DG.

Development. 2005 Feb;132(4):775-85. Epub 2005 Jan 19.


Diverse roles of eph receptors and ephrins in the regulation of cell migration and tissue assembly.

Poliakov A, Cotrina M, Wilkinson DG.

Dev Cell. 2004 Oct;7(4):465-80. Review.


A vertebrate crossveinless 2 homologue modulates BMP activity and neural crest cell migration.

Coles E, Christiansen J, Economou A, Bronner-Fraser M, Wilkinson DG.

Development. 2004 Nov;131(21):5309-17. Epub 2004 Sep 29.


Establishing neuronal circuitry: Hox genes make the connection.

Briscoe J, Wilkinson DG.

Genes Dev. 2004 Jul 15;18(14):1643-8. No abstract available.


Cholinesterase inhibitors used in the treatment of Alzheimer's disease: the relationship between pharmacological effects and clinical efficacy.

Wilkinson DG, Francis PT, Schwam E, Payne-Parrish J.

Drugs Aging. 2004;21(7):453-78. Review.


Notch activation regulates the segregation and differentiation of rhombomere boundary cells in the zebrafish hindbrain.

Cheng YC, Amoyel M, Qiu X, Jiang YJ, Xu Q, Wilkinson DG.

Dev Cell. 2004 Apr;6(4):539-50.


A randomised placebo controlled study to assess the effects of cholinergic treatment on muscarinic receptors in Alzheimer's disease.

Kemp PM, Holmes C, Hoffmann S, Wilkinson S, Zivanovic M, Thom J, Bolt L, Fleming J, Wilkinson DG.

J Neurol Neurosurg Psychiatry. 2003 Nov;74(11):1567-70.


How attraction turns to repulsion.

Wilkinson DG.

Nat Cell Biol. 2003 Oct;5(10):851-3. No abstract available.


Galantamine provides broad benefits in patients with 'advanced moderate' Alzheimer's disease (MMSE < or = 12) for up to six months.

Wilkinson DG, Hock C, Farlow M, van Baelen B, Schwalen S.

Int J Clin Pract. 2002 Sep;56(7):509-14.


A multinational, randomised, 12-week, comparative study of donepezil and rivastigmine in patients with mild to moderate Alzheimer's disease.

Wilkinson DG, Passmore AP, Bullock R, Hopker SW, Smith R, Potocnik FC, Maud CM, Engelbrecht I, Hock C, Ieni JR, Bahra RS.

Int J Clin Pract. 2002 Jul-Aug;56(6):441-6.


Stabilizing the regionalisation of the developing vertebrate central nervous system.

Pasini A, Wilkinson DG.

Bioessays. 2002 May;24(5):427-38. Review.


Requirement for downregulation of kreisler during late patterning of the hindbrain.

Theil T, Ariza-McNaughton L, Manzanares M, Brodie J, Krumlauf R, Wilkinson DG.

Development. 2002 Mar;129(6):1477-85.

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