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Items: 22


Development and evaluation of a computable phenotype to identify pediatric patients with leukemia and lymphoma treated with chemotherapy using electronic health record data.

Phillips CA, Razzaghi H, Aglio T, McNeil MJ, Salvesen-Quinn M, Sopfe J, Wilkes JJ, Forrest CB, Bailey LC.

Pediatr Blood Cancer. 2019 Sep;66(9):e27876. doi: 10.1002/pbc.27876. Epub 2019 Jun 17.


Outcome of children with multiply relapsed B-cell acute lymphoblastic leukemia: a therapeutic advances in childhood leukemia & lymphoma study.

Sun W, Malvar J, Sposto R, Verma A, Wilkes JJ, Dennis R, Heym K, Laetsch TW, Widener M, Rheingold SR, Oesterheld J, Hijiya N, Sulis ML, Huynh V, Place AE, Bittencourt H, Hutchinson R, Messinger Y, Chang B, Matloub Y, Ziegler DS, Gardner R, Cooper T, Ceppi F, Hermiston M, Dalla-Pozza L, Schultz KR, Gaynon P, Wayne AS, Whitlock JA.

Leukemia. 2018 Nov;32(11):2316-2325. doi: 10.1038/s41375-018-0094-0. Epub 2018 Mar 15.


Discovery of Potent and Orally Bioavailable Dihydropyrazole GPR40 Agonists.

Shi J, Gu Z, Jurica EA, Wu X, Haque LE, Williams KN, Hernandez AS, Hong Z, Gao Q, Dabros M, Davulcu AH, Mathur A, Rampulla RA, Gupta AK, Jayaram R, Apedo A, Moore DB, Liu H, Kunselman LK, Brady EJ, Wilkes JJ, Zinker BA, Cai H, Shu YZ, Sun Q, Dierks EA, Foster KA, Xu C, Wang T, Panemangalore R, Cvijic ME, Xie C, Cao GG, Zhou M, Krupinski J, Whaley JM, Robl JA, Ewing WR, Ellsworth BA.

J Med Chem. 2018 Feb 8;61(3):681-694. doi: 10.1021/acs.jmedchem.7b00982. Epub 2018 Jan 27.


Multisite external validation of a risk prediction model for the diagnosis of blood stream infections in febrile pediatric oncology patients without severe neutropenia.

Esbenshade AJ, Zhao Z, Aftandilian C, Saab R, Wattier RL, Beauchemin M, Miller TP, Wilkes JJ, Kelly MJ, Fernbach A, Jeng M, Schwartz CL, Dvorak CC, Shyr Y, Moons KGM, Sulis ML, Friedman DL.

Cancer. 2017 Oct 1;123(19):3781-3790. doi: 10.1002/cncr.30792. Epub 2017 May 23. Erratum in: Cancer. 2018 Apr 15;124(8):1841-1844.


Discovery of Pyrrolidine-Containing GPR40 Agonists: Stereochemistry Effects a Change in Binding Mode.

Jurica EA, Wu X, Williams KN, Hernandez AS, Nirschl DS, Rampulla RA, Mathur A, Zhou M, Cao G, Xie C, Jacob B, Cai H, Wang T, Murphy BJ, Liu H, Xu C, Kunselman LK, Hicks MB, Sun Q, Schnur DM, Sitkoff DF, Dierks EA, Apedo A, Moore DB, Foster KA, Cvijic ME, Panemangalore R, Flynn NA, Maxwell BD, Hong Y, Tian Y, Wilkes JJ, Zinker BA, Whaley JM, Barrish JC, Robl JA, Ewing WR, Ellsworth BA.

J Med Chem. 2017 Feb 23;60(4):1417-1431. doi: 10.1021/acs.jmedchem.6b01559. Epub 2017 Feb 9.


The role of acuity of illness at presentation in early mortality in black children with acute myeloid leukemia.

Winestone LE, Getz KD, Miller TP, Wilkes JJ, Sack L, Li Y, Huang YS, Seif AE, Bagatell R, Fisher BT, Epstein AJ, Aplenc R.

Am J Hematol. 2017 Feb;92(2):141-148. doi: 10.1002/ajh.24605. Epub 2016 Dec 7.


Low rates of pregnancy screening in adolescents before teratogenic exposures in a national sample of children's hospitals.

Rao P, Li Y, Getz KD, Miller TP, Huang YS, Wilkes JJ, Seif AE, Bagatell R, Fisher BT, Gracia C, Aplenc R.

Cancer. 2016 Nov 15;122(21):3394-3400. doi: 10.1002/cncr.30225. Epub 2016 Sep 12.


Treatment-related adverse events associated with a modified UK ALLR3 induction chemotherapy backbone for childhood relapsed/refractory acute lymphoblastic leukemia.

Sun W, Orgel E, Malvar J, Sposto R, Wilkes JJ, Gardner R, Tolbert VP, Smith A, Hur M, Hoffman J, Rheingold SR, Burke MJ, Wayne AS.

Pediatr Blood Cancer. 2016 Nov;63(11):1943-8. doi: 10.1002/pbc.26129. Epub 2016 Jul 20.


Volume-Outcome Relationships in Pediatric Acute Lymphoblastic Leukemia: Association Between Hospital Pediatric and Pediatric Oncology Volume With Mortality and Intensive Care Resources During Initial Therapy.

Wilkes JJ, Hennessy S, Xiao R, Rheingold S, Seif AE, Huang YS, Vendetti N, Li Y, Bagatell R, Aplenc R, Fisher BT.

Clin Lymphoma Myeloma Leuk. 2016 Jul;16(7):404-410.e1. doi: 10.1016/j.clml.2016.04.016. Epub 2016 May 4.


Severe hemolytic transfusion reaction due to anti-D in a D+ patient with sickle cell disease.

Ipe TS, Wilkes JJ, Hartung HD, Westhoff CM, Chou ST, Friedman DF.

J Pediatr Hematol Oncol. 2015 Mar;37(2):e135-7. doi: 10.1097/MPH.0000000000000241.


fdg-pet in two cases of neurofibromatosis type 1 and atypical malignancies.

de Blank P, Cole K, Kersun L, Green A, Wilkes JJ, Belasco J, Bagatell R, Bailey LC, Fisher MJ.

Curr Oncol. 2014 Apr;21(2):e345-8. doi: 10.3747/co.21.1803.


Use of antibiotics in children hospitalized with community-acquired, laboratory-confirmed influenza.

Wilkes JJ, Leckerman KH, Coffin SE, Keren R, Metjian TA, Hodinka RL, Zaoutis TE.

J Pediatr. 2009 Mar;154(3):447-9. doi: 10.1016/j.jpeds.2008.09.026.


Treatment with oseltamivir in children hospitalized with community-acquired, laboratory-confirmed influenza: review of five seasons and evaluation of an electronic reminder.

Wilkes JJ, Zaoutis TE, Keren R, Desai B, Leckerman KH, Hodinka RL, Metjian TA, Coffin SE.

J Hosp Med. 2009 Mar;4(3):171-8. doi: 10.1002/jhm.431.


Loss-of-function mutation in myostatin reduces tumor necrosis factor alpha production and protects liver against obesity-induced insulin resistance.

Wilkes JJ, Lloyd DJ, Gekakis N.

Diabetes. 2009 May;58(5):1133-43. doi: 10.2337/db08-0245. Epub 2009 Feb 10.


Topiramate treatment causes skeletal muscle insulin sensitization and increased Acrp30 secretion in high-fat-fed male Wistar rats.

Wilkes JJ, Nguyen MT, Bandyopadhyay GK, Nelson E, Olefsky JM.

Am J Physiol Endocrinol Metab. 2005 Dec;289(6):E1015-22. Epub 2005 Jul 19.


Topiramate is an insulin-sensitizing compound in vivo with direct effects on adipocytes in female ZDF rats.

Wilkes JJ, Nelson E, Osborne M, Demarest KT, Olefsky JM.

Am J Physiol Endocrinol Metab. 2005 Mar;288(3):E617-24. Epub 2004 Nov 9.


Chronic endothelin-1 treatment leads to insulin resistance in vivo.

Wilkes JJ, Hevener A, Olefsky J.

Diabetes. 2003 Aug;52(8):1904-9.


Tyrosine phosphorylation of p190 RhoGAP by Fyn regulates oligodendrocyte differentiation.

Wolf RM, Wilkes JJ, Chao MV, Resh MD.

J Neurobiol. 2001 Oct;49(1):62-78.


A modified high-fat diet induces insulin resistance in rat skeletal muscle but not adipocytes.

Wilkes JJ, Bonen A, Bell RC.

Am J Physiol. 1998 Oct;275(4):E679-86. doi: 10.1152/ajpendo.1998.275.4.E679.


Chronic ethanol feeding in a high-fat diet decreases insulin-stimulated glucose transport in rat adipocytes.

Wilkes JJ, DeForrest LL, Nagy LE.

Am J Physiol. 1996 Sep;271(3 Pt 1):E477-84.


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