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Items: 1 to 50 of 124

1.

Collagen type-V is a danger signal associated with primary graft dysfunction in lung transplantation.

Zaffiri L, Shah RJ, Stearman RS, Rothhaar K, Emtiazjoo AM, Yoshimoto M, Fisher AJ, Mickler EA, Gartenhaus MD, Cohort LTOG, Diamond JM, Geraci MW, Christie JD, Wilkes DS.

Transpl Immunol. 2019 Oct;56:101224. doi: 10.1016/j.trim.2019.101224. Epub 2019 Jul 17.

PMID:
31325493
2.

Vendor-specific microbiome controls both acute and chronic murine lung allograft rejection by altering CD4+ Foxp3+ regulatory T cell levels.

Guo Y, Wang Q, Li D, Onyema OO, Mei Z, Manafi A, Banerjee A, Mahgoub B, Stoler MH, Barker TH, Wilkes DS, Gelman AE, Kreisel D, Krupnick AS.

Am J Transplant. 2019 Oct;19(10):2705-2718. doi: 10.1111/ajt.15523. Epub 2019 Aug 2.

PMID:
31278849
3.

Correction: Type V Collagen Induced Tolerance Suppresses Collagen Deposition, TGF-β and Associated Transcripts in Pulmonary Fibrosis.

Vittal R, Mickler EA, Fisher AJ, Zhang C, Rothhaar K, Gu H, Brown KM, Emtiazjoo A, Lott JM, Frye SB, Smith GN, Sandusky GE, Cummings OW, Wilkes DS.

PLoS One. 2018 Dec 6;13(12):e0209107. doi: 10.1371/journal.pone.0209107. eCollection 2018.

4.

Leukocyte-Associated Ig-like Receptor 1 Inhibits Th1 Responses but Is Required for Natural and Induced Monocyte-Dependent Th17 Responses.

Agashe VV, Jankowska-Gan E, Keller M, Sullivan JA, Haynes LD, Kernien JF, Torrealba JR, Roenneburg D, Dart M, Colonna M, Wilkes DS, Burlingham WJ.

J Immunol. 2018 Jul 15;201(2):772-781. doi: 10.4049/jimmunol.1701753. Epub 2018 Jun 8.

5.

Clinical Risk Factors and Prognostic Model for Primary Graft Dysfunction after Lung Transplantation in Patients with Pulmonary Hypertension.

Porteous MK, Lee JC, Lederer DJ, Palmer SM, Cantu E, Shah RJ, Bellamy SL, Lama VN, Bhorade SM, Crespo MM, McDyer JF, Wille KM, Localio AR, Orens JB, Shah PD, Weinacker AB, Arcasoy S, Wilkes DS, Ware LB, Christie JD, Kawut SM, Diamond JM; Lung Transplant Outcomes Group.

Ann Am Thorac Soc. 2017 Oct;14(10):1514-1522. doi: 10.1513/AnnalsATS.201610-810OC.

6.

An activated Th17-prone T cell subset involved in chronic graft-versus-host disease sensitive to pharmacological inhibition.

Forcade E, Paz K, Flynn R, Griesenauer B, Amet T, Li W, Liu L, Bakoyannis G, Jiang D, Chu HW, Lobera M, Yang J, Wilkes DS, Du J, Gartlan K, Hill GR, MacDonald KP, Espada EL, Blanco P, Serody JS, Koreth J, Cutler CS, Antin JH, Soiffer RJ, Ritz J, Paczesny S, Blazar BR.

JCI Insight. 2017 Jun 15;2(12). pii: 92111. doi: 10.1172/jci.insight.92111. eCollection 2017 Jun 15.

7.

Models of Lung Transplant Research: a consensus statement from the National Heart, Lung, and Blood Institute workshop.

Lama VN, Belperio JA, Christie JD, El-Chemaly S, Fishbein MC, Gelman AE, Hancock WW, Keshavjee S, Kreisel D, Laubach VE, Looney MR, McDyer JF, Mohanakumar T, Shilling RA, Panoskaltsis-Mortari A, Wilkes DS, Eu JP, Nicolls MR.

JCI Insight. 2017 May 4;2(9). pii: 93121. doi: 10.1172/jci.insight.93121. eCollection 2017 May 4. Review.

8.

Th17 Responses to Collagen Type V, kα1-Tubulin, and Vimentin Are Present Early in Human Development and Persist Throughout Life.

Sullivan JA, Jankowska-Gan E, Hegde S, Pestrak MA, Agashe VV, Park AC, Brown ME, Kernien JF, Wilkes DS, Kaufman DB, Greenspan DS, Burlingham WJ.

Am J Transplant. 2017 Apr;17(4):944-956. doi: 10.1111/ajt.14097. Epub 2016 Dec 19.

9.

Hypoxia-Inducible Factor-1α Regulates CD55 in Airway Epithelium.

Pandya PH, Fisher AJ, Mickler EA, Temm CJ, Lipking KP, Gracon A, Rothhaar K, Sandusky GE, Murray M, Pollok K, Renbarger J, Blum JS, Lahm T, Wilkes DS.

Am J Respir Cell Mol Biol. 2016 Dec;55(6):889-898.

10.

Regulation of Collagen V Expression and Epithelial-Mesenchymal Transition by miR-185 and miR-186 during Idiopathic Pulmonary Fibrosis.

Lei GS, Kline HL, Lee CH, Wilkes DS, Zhang C.

Am J Pathol. 2016 Sep;186(9):2310-6. doi: 10.1016/j.ajpath.2016.04.015. Epub 2016 Jul 5.

11.

Human leukocyte antigen-DR13 and DR15 are associated with short-term lung transplant outcomes.

Gracon AS, Liang TW, Rothhaar K, Wu J, Wilkes DS.

J Surg Res. 2016 Jun 1;203(1):82-90. doi: 10.1016/j.jss.2016.03.041. Epub 2016 Mar 26.

PMID:
27338538
12.

National Heart, Lung, and Blood Institute Workshop Summary: Enhancing Opportunities for Training and Retention of a Diverse Biomedical Workforce.

Duncan GA, Lockett A, Villegas LR, Almodovar S, Gomez JL, Flores SC, Wilkes DS, Tigno XT.

Ann Am Thorac Soc. 2016 Apr;13(4):562-7. doi: 10.1513/AnnalsATS.201509-624OT.

13.

Contribution of the anaphylatoxin receptors, C3aR and C5aR, to the pathogenesis of pulmonary fibrosis.

Gu H, Fisher AJ, Mickler EA, Duerson F 3rd, Cummings OW, Peters-Golden M, Twigg HL 3rd, Woodruff TM, Wilkes DS, Vittal R.

FASEB J. 2016 Jun;30(6):2336-50. doi: 10.1096/fj.201500044. Epub 2016 Mar 8.

14.

Proteomic Characterization Reveals That MMP-3 Correlates With Bronchiolitis Obliterans Syndrome Following Allogeneic Hematopoietic Cell and Lung Transplantation.

Liu X, Yue Z, Yu J, Daguindau E, Kushekhar K, Zhang Q, Ogata Y, Gafken PR, Inamoto Y, Gracon A, Wilkes DS, Hansen JA, Lee SJ, Chen JY, Paczesny S.

Am J Transplant. 2016 Aug;16(8):2342-51. doi: 10.1111/ajt.13750. Epub 2016 Mar 14.

15.

The relationship between plasma lipid peroxidation products and primary graft dysfunction after lung transplantation is modified by donor smoking and reperfusion hyperoxia.

Diamond JM, Porteous MK, Roberts LJ 2nd, Wickersham N, Rushefski M, Kawut SM, Shah RJ, Cantu E 3rd, Lederer DJ, Chatterjee S, Lama VN, Bhorade S, Crespo M, McDyer J, Wille K, Orens J, Weinacker A, Arcasoy S, Shah PD, Wilkes DS, Hage C, Palmer SM, Snyder L, Calfee CS, Ware LB, Christie JD; Lung Transplant Outcomes Group.

J Heart Lung Transplant. 2016 Apr;35(4):500-507. doi: 10.1016/j.healun.2015.12.012. Epub 2016 Jan 7.

16.

Mucosal Administration of Collagen V Ameliorates the Atherosclerotic Plaque Burden by Inducing Interleukin 35-dependent Tolerance.

Park AC, Huang G, Jankowska-Gan E, Massoudi D, Kernien JF, Vignali DA, Sullivan JA, Wilkes DS, Burlingham WJ, Greenspan DS.

J Biol Chem. 2016 Feb 12;291(7):3359-70. doi: 10.1074/jbc.M115.681882. Epub 2015 Dec 31.

17.

Exploring autoimmunity in the pathogenesis of abdominal aortic aneurysms.

Chang TW, Gracon AS, Murphy MP, Wilkes DS.

Am J Physiol Heart Circ Physiol. 2015 Sep;309(5):H719-27. doi: 10.1152/ajpheart.00273.2015. Epub 2015 Jun 26. Review.

18.

Objective Estimates Improve Risk Stratification for Primary Graft Dysfunction after Lung Transplantation.

Shah RJ, Diamond JM, Cantu E, Flesch J, Lee JC, Lederer DJ, Lama VN, Orens J, Weinacker A, Wilkes DS, Roe D, Bhorade S, Wille KM, Ware LB, Palmer SM, Crespo M, Demissie E, Sonnet J, Shah A, Kawut SM, Bellamy SL, Localio AR, Christie JD.

Am J Transplant. 2015 Aug;15(8):2188-96. doi: 10.1111/ajt.13262. Epub 2015 Apr 15.

19.

CD4 T Cells but Not Th17 Cells Are Required for Mouse Lung Transplant Obliterative Bronchiolitis.

Wu Q, Gupta PK, Suzuki H, Wagner SR, Zhang C, W Cummings O, Fan L, Kaplan MH, Wilkes DS, Shilling RA.

Am J Transplant. 2015 Jul;15(7):1793-1804. doi: 10.1111/ajt.13215. Epub 2015 Mar 13.

20.

The HMGB1-RAGE Inflammatory Pathway: Implications for Brain Injury-Induced Pulmonary Dysfunction.

Weber DJ, Allette YM, Wilkes DS, White FA.

Antioxid Redox Signal. 2015 Dec 10;23(17):1316-28. doi: 10.1089/ars.2015.6299. Epub 2015 May 14. Review.

21.

Oral immunotherapy with type V collagen in idiopathic pulmonary fibrosis.

Wilkes DS, Chew T, Flaherty KR, Frye S, Gibson KF, Kaminski N, Klemsz MJ, Lange W, Noth I, Rothhaar K.

Eur Respir J. 2015 May;45(5):1393-402. doi: 10.1183/09031936.00105314. Epub 2015 Jan 22.

22.

Why is the patient out of breath? Collagen V(α1) and K-α1-tubulin take center stage in lung transplantation.

Burlingham W, Wilkes DS, Sullivan JA.

Am J Transplant. 2014 Oct;14(10):2201-3. doi: 10.1111/ajt.12910. Epub 2014 Sep 12. No abstract available.

23.

The HMGB1-RAGE axis mediates traumatic brain injury-induced pulmonary dysfunction in lung transplantation.

Weber DJ, Gracon AS, Ripsch MS, Fisher AJ, Cheon BM, Pandya PH, Vittal R, Capitano ML, Kim Y, Allette YM, Riley AA, McCarthy BP, Territo PR, Hutchins GD, Broxmeyer HE, Sandusky GE, White FA, Wilkes DS.

Sci Transl Med. 2014 Sep 3;6(252):252ra124. doi: 10.1126/scitranslmed.3009443. Retraction in: Sci Transl Med. 2018 Dec 12;10(471):.

24.

Blockade of the programmed death-1 pathway restores sarcoidosis CD4(+) T-cell proliferative capacity.

Braun NA, Celada LJ, Herazo-Maya JD, Abraham S, Shaginurova G, Sevin CM, Grutters J, Culver DA, Dworski R, Sheller J, Massion PP, Polosukhin VV, Johnson JE, Kaminski N, Wilkes DS, Oswald-Richter KA, Drake WP.

Am J Respir Crit Care Med. 2014 Sep 1;190(5):560-71. doi: 10.1164/rccm.201401-0188OC.

25.

Lung transplantation: chronic allograft dysfunction and establishing immune tolerance.

Gracon AS, Wilkes DS.

Hum Immunol. 2014 Aug;75(8):887-94. doi: 10.1016/j.humimm.2014.06.015. Epub 2014 Jun 27. Review.

26.

Crosstalk between TGF-β1 and complement activation augments epithelial injury in pulmonary fibrosis.

Gu H, Mickler EA, Cummings OW, Sandusky GE, Weber DJ, Gracon A, Woodruff T, Wilkes DS, Vittal R.

FASEB J. 2014 Oct;28(10):4223-34. doi: 10.1096/fj.13-247650. Epub 2014 Jun 23.

27.

Plasma complement levels are associated with primary graft dysfunction and mortality after lung transplantation.

Shah RJ, Emtiazjoo AM, Diamond JM, Smith PA, Roe DW, Wille KM, Orens JB, Ware LB, Weinacker A, Lama VN, Bhorade SM, Palmer SM, Crespo M, Lederer DJ, Cantu E, Eckert GJ, Christie JD, Wilkes DS.

Am J Respir Crit Care Med. 2014 Jun 15;189(12):1564-7. doi: 10.1164/rccm.201312-2121LE. No abstract available.

28.

Complement system in lung disease.

Pandya PH, Wilkes DS.

Am J Respir Cell Mol Biol. 2014 Oct;51(4):467-73. doi: 10.1165/rcmb.2013-0485TR. Review.

29.

Differential requirement for P2X7R function in IL-17 dependent vs. IL-17 independent cellular immune responses.

Sullivan JA, Jankowska-Gan E, Shi L, Roenneburg D, Hegde S, Greenspan DS, Wilkes DS, Denlinger LC, Burlingham WJ.

Am J Transplant. 2014 Jul;14(7):1512-22. doi: 10.1111/ajt.12741. Epub 2014 May 27.

30.

Leveraging diversity in American academic medicine. The Harold Amos medical faculty development program.

Ardery NL, Krol DM, Wilkes DS.

Ann Am Thorac Soc. 2014 May;11(4):600-2. doi: 10.1513/AnnalsATS.201402-064PS. No abstract available.

PMID:
24708173
31.

Preoperative plasma club (clara) cell secretory protein levels are associated with primary graft dysfunction after lung transplantation.

Shah RJ, Wickersham N, Lederer DJ, Palmer SM, Cantu E, Diamond JM, Kawut SM, Lama VN, Bhorade S, Crespo M, Demissie E, Sonett J, Wille K, Orens J, Weinacker A, Shah P, Arcasoy S, Wilkes DS, Christie JD, Ware LB; Lung Transplant Outcomes Group.

Am J Transplant. 2014 Feb;14(2):446-52. doi: 10.1111/ajt.12541. Epub 2014 Jan 8.

32.

Type V collagen induced tolerance suppresses collagen deposition, TGF-β and associated transcripts in pulmonary fibrosis.

Vittal R, Mickler EA, Fisher AJ, Zhang C, Rothhaar K, Gu H, Brown KM, Emtiazjoo A, Lott JM, Frye SB, Smith GN, Sandusky GE, Cummings OW, Wilkes DS.

PLoS One. 2013 Oct 21;8(10):e76451. doi: 10.1371/journal.pone.0076451. eCollection 2013. Erratum in: PLoS One. 2018 Dec 6;13(12):e0209107.

33.

Role of complement activation in obliterative bronchiolitis post-lung transplantation.

Suzuki H, Lasbury ME, Fan L, Vittal R, Mickler EA, Benson HL, Shilling R, Wu Q, Weber DJ, Wagner SR, Lasaro M, Devore D, Wang Y, Sandusky GE, Lipking K, Pandya P, Reynolds J, Love R, Wozniak T, Gu H, Brown KM, Wilkes DS.

J Immunol. 2013 Oct 15;191(8):4431-9. doi: 10.4049/jimmunol.1202242. Epub 2013 Sep 16.

34.

Reversal of global CD4+ subset dysfunction is associated with spontaneous clinical resolution of pulmonary sarcoidosis.

Oswald-Richter KA, Richmond BW, Braun NA, Isom J, Abraham S, Taylor TR, Drake JM, Culver DA, Wilkes DS, Drake WP.

J Immunol. 2013 Jun 1;190(11):5446-53. doi: 10.4049/jimmunol.1202891. Epub 2013 Apr 29.

35.

Allergic airway disease in mice alters T and B cell responses during an acute respiratory poxvirus infection.

Walline CC, Sehra S, Fisher AJ, Guindon LM, Kratzke IM, Montgomery JB, Lipking KP, Glosson NL, Benson HL, Sandusky GE, Wilkes DS, Brutkiewicz RR, Kaplan MH, Blum JS.

PLoS One. 2013 Apr 19;8(4):e62222. doi: 10.1371/journal.pone.0062222. Print 2013.

36.

Peptide-mediated inhibition of mitogen-activated protein kinase-activated protein kinase-2 ameliorates bleomycin-induced pulmonary fibrosis.

Vittal R, Fisher A, Gu H, Mickler EA, Panitch A, Lander C, Cummings OW, Sandusky GE, Wilkes DS.

Am J Respir Cell Mol Biol. 2013 Jul;49(1):47-57. doi: 10.1165/rcmb.2012-0389OC.

37.

Latent class analysis identifies distinct phenotypes of primary graft dysfunction after lung transplantation.

Shah RJ, Diamond JM, Cantu E, Lee JC, Lederer DJ, Lama VN, Orens J, Weinacker A, Wilkes DS, Bhorade S, Wille KM, Ware LB, Palmer SM, Crespo M, Localio AR, Demissie E, Kawut SM, Bellamy SL, Christie JD.

Chest. 2013 Aug;144(2):616-622. doi: 10.1378/chest.12-1480.

38.

Type V collagen-induced tolerance prevents airway hyperresponsiveness.

Lott JM, Sehra S, Mehrotra P, Mickler EA, Fisher AJ, Zhang W, Presson RG, Busk MF, Goenka S, Gunst SJ, Kaplan MH, Wilkes DS, Wenzel SE.

Am J Respir Crit Care Med. 2013 Feb 15;187(4):454-7. No abstract available.

39.

Interleukin-9 is required for allergic airway inflammation mediated by the cytokine TSLP.

Yao W, Zhang Y, Jabeen R, Nguyen ET, Wilkes DS, Tepper RS, Kaplan MH, Zhou B.

Immunity. 2013 Feb 21;38(2):360-72. doi: 10.1016/j.immuni.2013.01.007. Epub 2013 Jan 31.

40.

Clinical risk factors for primary graft dysfunction after lung transplantation.

Diamond JM, Lee JC, Kawut SM, Shah RJ, Localio AR, Bellamy SL, Lederer DJ, Cantu E, Kohl BA, Lama VN, Bhorade SM, Crespo M, Demissie E, Sonett J, Wille K, Orens J, Shah AS, Weinacker A, Arcasoy S, Shah PD, Wilkes DS, Ware LB, Palmer SM, Christie JD; Lung Transplant Outcomes Group.

Am J Respir Crit Care Med. 2013 Mar 1;187(5):527-34. doi: 10.1164/rccm.201210-1865OC. Epub 2013 Jan 10.

41.

Elevated plasma angiopoietin-2 levels and primary graft dysfunction after lung transplantation.

Diamond JM, Porteous MK, Cantu E, Meyer NJ, Shah RJ, Lederer DJ, Kawut SM, Lee J, Bellamy SL, Palmer SM, Lama VN, Bhorade SM, Crespo M, Demissie E, Wille K, Orens J, Shah PD, Weinacker A, Weill D, Arcasoy S, Wilkes DS, Ware LB, Christie JD; Lung Transplant Outcomes Group.

PLoS One. 2012;7(12):e51932. doi: 10.1371/journal.pone.0051932. Epub 2012 Dec 19.

42.

IL-17 induces type V collagen overexpression and EMT via TGF-β-dependent pathways in obliterative bronchiolitis.

Vittal R, Fan L, Greenspan DS, Mickler EA, Gopalakrishnan B, Gu H, Benson HL, Zhang C, Burlingham W, Cummings OW, Wilkes DS.

Am J Physiol Lung Cell Mol Physiol. 2013 Mar 15;304(6):L401-14. doi: 10.1152/ajplung.00080.2012. Epub 2012 Dec 21.

43.

The role of autoimmunity in obliterative bronchiolitis after lung transplantation.

Weber DJ, Wilkes DS.

Am J Physiol Lung Cell Mol Physiol. 2013 Mar 1;304(5):L307-11. doi: 10.1152/ajplung.00378.2012. Epub 2012 Dec 21. Review.

44.

Humoral immunity and the development of obliterative bronchiolitis after lung transplantation: is there a link?

Emtiazjoo AM, Wilkes DS.

Am J Respir Cell Mol Biol. 2013 Feb;48(2):145-9. doi: 10.1165/rcmb.2012-0349RT. Epub 2012 Oct 18. Review.

45.

Development of obliterative bronchiolitis in a murine model of orthotopic lung transplantation.

Suzuki H, Fan L, Wilkes DS.

J Vis Exp. 2012 Jul 10;(65). pii: 3947. doi: 10.3791/3947.

46.

Comparison of pulmonary complications after nonmyeloablative and conventional allogeneic hematopoietic cell transplant.

Diab KJ, Yu Z, Wood KL, Shmalo JA, Sheski FD, Farber MO, Wilkes DS, Nelson RP Jr.

Biol Blood Marrow Transplant. 2012 Dec;18(12):1827-34. doi: 10.1016/j.bbmt.2012.06.013. Epub 2012 Jul 2.

47.

A panel of lung injury biomarkers enhances the definition of primary graft dysfunction (PGD) after lung transplantation.

Shah RJ, Bellamy SL, Localio AR, Wickersham N, Diamond JM, Weinacker A, Lama VN, Bhorade S, Belperio JA, Crespo M, Demissie E, Kawut SM, Wille KM, Lederer DJ, Lee JC, Palmer SM, Orens J, Reynolds J, Shah A, Wilkes DS, Ware LB, Christie JD.

J Heart Lung Transplant. 2012 Sep;31(9):942-9. doi: 10.1016/j.healun.2012.05.001. Epub 2012 Jun 12.

48.

Donor lung derived myeloid and plasmacytoid dendritic cells differentially regulate T cell proliferation and cytokine production.

Benson HL, Suzuki H, Lott J, Fisher AJ, Walline C, Heidler KM, Brutkiewicz R, Blum JS, Wilkes DS.

Respir Res. 2012 Mar 20;13:25. doi: 10.1186/1465-9921-13-25.

49.

Matrix metalloproteinases in T cell mediated pulmonary diseases.

Benson HL, Wilkes DS.

Front Biosci (Elite Ed). 2012 Jan 1;4:2162-9. Review.

PMID:
22202028
50.

Autoantibody formation in human and rat studies of chronic rejection and primary graft dysfunction.

Wilkes DS.

Semin Immunol. 2012 Apr;24(2):131-5. doi: 10.1016/j.smim.2011.08.020. Epub 2011 Sep 16. Review.

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