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Items: 22

1.

Myeloid cell-synthesized coagulation factor X dampens antitumor immunity.

Graf C, Wilgenbus P, Pagel S, Pott J, Marini F, Reyda S, Kitano M, Macher-Göppinger S, Weiler H, Ruf W.

Sci Immunol. 2019 Sep 20;4(39). pii: eaaw8405. doi: 10.1126/sciimmunol.aaw8405.

PMID:
31541031
2.

Paraoxonase-2 regulates coagulation activation through endothelial tissue factor.

Ebert J, Wilgenbus P, Teiber JF, Jurk K, Schwierczek K, Döhrmann M, Xia N, Li H, Spiecker L, Ruf W, Horke S.

Blood. 2018 May 10;131(19):2161-2172. doi: 10.1182/blood-2017-09-807040. Epub 2018 Feb 9.

PMID:
29439952
3.

The anti-apoptotic PON2 protein is Wnt/β-catenin-regulated and correlates with radiotherapy resistance in OSCC patients.

Krüger M, Amort J, Wilgenbus P, Helmstädter JP, Grechowa I, Ebert J, Tenzer S, Moergel M, Witte I, Horke S.

Oncotarget. 2016 Aug 9;7(32):51082-51095. doi: 10.18632/oncotarget.9013.

4.

Novel Paraoxonase 2-Dependent Mechanism Mediating the Biological Effects of the Pseudomonas aeruginosa Quorum-Sensing Molecule N-(3-Oxo-Dodecanoyl)-L-Homoserine Lactone.

Horke S, Xiao J, Schütz EM, Kramer GL, Wilgenbus P, Witte I, Selbach M, Teiber JF.

Infect Immun. 2015 Sep;83(9):3369-80. doi: 10.1128/IAI.00141-15. Epub 2015 Jun 8.

5.

Paraoxonases-2 and -3 Are Important Defense Enzymes against Pseudomonas aeruginosa Virulence Factors due to Their Anti-Oxidative and Anti-Inflammatory Properties.

Schweikert EM, Amort J, Wilgenbus P, Förstermann U, Teiber JF, Horke S.

J Lipids. 2012;2012:352857. doi: 10.1155/2012/352857. Epub 2012 Apr 12.

6.

PON3 is upregulated in cancer tissues and protects against mitochondrial superoxide-mediated cell death.

Schweikert EM, Devarajan A, Witte I, Wilgenbus P, Amort J, Förstermann U, Shabazian A, Grijalva V, Shih DM, Farias-Eisner R, Teiber JF, Reddy ST, Horke S.

Cell Death Differ. 2012 Sep;19(9):1549-60. doi: 10.1038/cdd.2012.35. Epub 2012 Mar 23.

7.

Beyond reduction of atherosclerosis: PON2 provides apoptosis resistance and stabilizes tumor cells.

Witte I, Altenhöfer S, Wilgenbus P, Amort J, Clement AM, Pautz A, Li H, Förstermann U, Horke S.

Cell Death Dis. 2011 Jan 13;2:e112. doi: 10.1038/cddis.2010.91.

8.

One enzyme, two functions: PON2 prevents mitochondrial superoxide formation and apoptosis independent from its lactonase activity.

Altenhöfer S, Witte I, Teiber JF, Wilgenbus P, Pautz A, Li H, Daiber A, Witan H, Clement AM, Förstermann U, Horke S.

J Biol Chem. 2010 Aug 6;285(32):24398-403. doi: 10.1074/jbc.M110.118604. Epub 2010 Jun 8.

9.

Paraoxonase 2 is down-regulated by the Pseudomonas aeruginosa quorumsensing signal N-(3-oxododecanoyl)-L-homoserine lactone and attenuates oxidative stress induced by pyocyanin.

Horke S, Witte I, Altenhöfer S, Wilgenbus P, Goldeck M, Förstermann U, Xiao J, Kramer GL, Haines DC, Chowdhary PK, Haley RW, Teiber JF.

Biochem J. 2010 Jan 27;426(1):73-83. doi: 10.1042/BJ20091414.

PMID:
19925453
10.

Protective effect of paraoxonase-2 against endoplasmic reticulum stress-induced apoptosis is lost upon disturbance of calcium homoeostasis.

Horke S, Witte I, Wilgenbus P, Altenhöfer S, Krüger M, Li H, Förstermann U.

Biochem J. 2008 Dec 15;416(3):395-405. doi: 10.1042/BJ20080775.

PMID:
18691157
11.

Paraoxonase-2 reduces oxidative stress in vascular cells and decreases endoplasmic reticulum stress-induced caspase activation.

Horke S, Witte I, Wilgenbus P, Krüger M, Strand D, Förstermann U.

Circulation. 2007 Apr 17;115(15):2055-64. Epub 2007 Apr 2.

PMID:
17404154
12.

Fibroblast growth factors are required for efficient tumor angiogenesis.

Compagni A, Wilgenbus P, Impagnatiello MA, Cotten M, Christofori G.

Cancer Res. 2000 Dec 15;60(24):7163-9.

13.

Reduced expression of neural cell adhesion molecule induces metastatic dissemination of pancreatic beta tumor cells.

Perl AK, Dahl U, Wilgenbus P, Cremer H, Semb H, Christofori G.

Nat Med. 1999 Mar;5(3):286-91.

PMID:
10086383
14.

Two Li-Fraumeni syndrome families with novel germline p53 mutations: loss of the wild-type p53 allele in only 50% of tumours.

Sedlacek Z, Kodet R, Kriz V, Seemanova E, Vodvarka P, Wilgenbus P, Mares J, Poustka A, Goetz P.

Br J Cancer. 1998 Apr;77(7):1034-9.

15.

A causal role for E-cadherin in the transition from adenoma to carcinoma.

Perl AK, Wilgenbus P, Dahl U, Semb H, Christofori G.

Nature. 1998 Mar 12;392(6672):190-3.

PMID:
9515965
16.

Chromosomal distribution of the hamster intracisternal A-particle (IAP) retrotransposons.

Meyer zu Altenschildesche G, Heller H, Wilgenbus P, Tjia ST, Doerfler W.

Chromosoma. 1996;104(5):341-4.

PMID:
8575245
17.

Identification of novel mutations in three families with Emery-Dreifuss muscular dystrophy.

Klauck SM, Wilgenbus P, Yates JR, Müller CR, Poustka A.

Hum Mol Genet. 1995 Oct;4(10):1853-7. No abstract available.

PMID:
8595406
18.
19.

On the insertion of foreign DNA into mammalian genomes: mechanism and consequences.

Doerfler W, Orend G, Schubbert R, Fechteler K, Heller H, Wilgenbus P, Schröer J.

Gene. 1995 May 19;157(1-2):241-5.

PMID:
7607499
20.

The mechanism of adenovirus DNA integration: studies in a cell-free system.

Fechteler K, Tatzelt J, Huppertz S, Wilgenbus P, Doerfler W.

Curr Top Microbiol Immunol. 1995;199 ( Pt 2):109-37. Review. No abstract available.

PMID:
7555065
21.

A radiation hybrid map of human chromosome 18.

Francke U, Chang E, Comeau K, Geigl EM, Giacalone J, Li X, Luna J, Moon A, Welch S, Wilgenbus P.

Cytogenet Cell Genet. 1994;66(3):196-213.

PMID:
8125019
22.

Mutation screening of complete fibrillin-1 coding sequence: report of five new mutations, including two in 8-cysteine domains.

Tynan K, Comeau K, Pearson M, Wilgenbus P, Levitt D, Gasner C, Berg MA, Miller DC, Francke U.

Hum Mol Genet. 1993 Nov;2(11):1813-21.

PMID:
8281141

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