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Items: 16


Sublethal antibiotics collapse gut bacterial populations by enhancing aggregation and expulsion.

Schlomann BH, Wiles TJ, Wall ES, Guillemin K, Parthasarathy R.

Proc Natl Acad Sci U S A. 2019 Oct 22;116(43):21392-21400. doi: 10.1073/pnas.1907567116. Epub 2019 Oct 7.


The Other Side of the Coin: What Beneficial Microbes Can Teach Us about Pathogenic Potential.

Wiles TJ, Guillemin K.

J Mol Biol. 2019 Jul 26;431(16):2946-2956. doi: 10.1016/j.jmb.2019.05.001. Epub 2019 May 9. Review.


Bacterial Cohesion Predicts Spatial Distribution in the Larval Zebrafish Intestine.

Schlomann BH, Wiles TJ, Wall ES, Guillemin K, Parthasarathy R.

Biophys J. 2018 Dec 4;115(11):2271-2277. doi: 10.1016/j.bpj.2018.10.017. Epub 2018 Oct 30.


Modernized Tools for Streamlined Genetic Manipulation and Comparative Study of Wild and Diverse Proteobacterial Lineages.

Wiles TJ, Wall ES, Schlomann BH, Hay EA, Parthasarathy R, Guillemin K.

MBio. 2018 Oct 9;9(5). pii: e01877-18. doi: 10.1128/mBio.01877-18.


The enteric nervous system promotes intestinal health by constraining microbiota composition.

Rolig AS, Mittge EK, Ganz J, Troll JV, Melancon E, Wiles TJ, Alligood K, Stephens WZ, Eisen JS, Guillemin K.

PLoS Biol. 2017 Feb 16;15(2):e2000689. doi: 10.1371/journal.pbio.2000689. eCollection 2017 Feb.


Best practices for germ-free derivation and gnotobiotic zebrafish husbandry.

Melancon E, Gomez De La Torre Canny S, Sichel S, Kelly M, Wiles TJ, Rawls JF, Eisen JS, Guillemin K.

Methods Cell Biol. 2017;138:61-100. doi: 10.1016/bs.mcb.2016.11.005. Review.


Host Gut Motility Promotes Competitive Exclusion within a Model Intestinal Microbiota.

Wiles TJ, Jemielita M, Baker RP, Schlomann BH, Logan SL, Ganz J, Melancon E, Eisen JS, Guillemin K, Parthasarathy R.

PLoS Biol. 2016 Jul 26;14(7):e1002517. doi: 10.1371/journal.pbio.1002517. eCollection 2016 Jul.


Strengths and Limitations of Model Systems for the Study of Urinary Tract Infections and Related Pathologies.

Barber AE, Norton JP, Wiles TJ, Mulvey MA.

Microbiol Mol Biol Rev. 2016 Mar 2;80(2):351-67. doi: 10.1128/MMBR.00067-15. Print 2016 Jun. Review.


Identification of Population Bottlenecks and Colonization Factors during Assembly of Bacterial Communities within the Zebrafish Intestine.

Stephens WZ, Wiles TJ, Martinez ES, Jemielita M, Burns AR, Parthasarathy R, Bohannan BJ, Guillemin K.

MBio. 2015 Oct 27;6(6):e01163-15. doi: 10.1128/mBio.01163-15.


Combining quantitative genetic footprinting and trait enrichment analysis to identify fitness determinants of a bacterial pathogen.

Wiles TJ, Norton JP, Russell CW, Dalley BK, Fischer KF, Mulvey MA.

PLoS Genet. 2013;9(8):e1003716. doi: 10.1371/journal.pgen.1003716. Epub 2013 Aug 22.


A phyletically rare gene promotes the niche-specific fitness of an E. coli pathogen during bacteremia.

Wiles TJ, Norton JP, Smith SN, Lewis AJ, Mobley HL, Casjens SR, Mulvey MA.

PLoS Pathog. 2013 Feb;9(2):e1003175. doi: 10.1371/journal.ppat.1003175. Epub 2013 Feb 14.


The RTX pore-forming toxin α-hemolysin of uropathogenic Escherichia coli: progress and perspectives.

Wiles TJ, Mulvey MA.

Future Microbiol. 2013 Jan;8(1):73-84. doi: 10.2217/fmb.12.131. Review.


The repeat-in-toxin family member TosA mediates adherence of uropathogenic Escherichia coli and survival during bacteremia.

Vigil PD, Wiles TJ, Engstrom MD, Prasov L, Mulvey MA, Mobley HL.

Infect Immun. 2012 Feb;80(2):493-505. doi: 10.1128/IAI.05713-11. Epub 2011 Nov 14.


Use of zebrafish to probe the divergent virulence potentials and toxin requirements of extraintestinal pathogenic Escherichia coli.

Wiles TJ, Bower JM, Redd MJ, Mulvey MA.

PLoS Pathog. 2009 Dec;5(12):e1000697. doi: 10.1371/journal.ppat.1000697. Epub 2009 Dec 18.


Origins and virulence mechanisms of uropathogenic Escherichia coli.

Wiles TJ, Kulesus RR, Mulvey MA.

Exp Mol Pathol. 2008 Aug;85(1):11-9. doi: 10.1016/j.yexmp.2008.03.007. Epub 2008 Apr 8. Review.


Inactivation of host Akt/protein kinase B signaling by bacterial pore-forming toxins.

Wiles TJ, Dhakal BK, Eto DS, Mulvey MA.

Mol Biol Cell. 2008 Apr;19(4):1427-38. doi: 10.1091/mbc.E07-07-0638. Epub 2008 Jan 30.

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