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Items: 45


The genome of the sea anemone Actinia equina (L.): Meiotic toolkit genes and the question of sexual reproduction.

Wilding CS, Fletcher N, Smith EK, Prentis P, Weedall GD, Stewart Z.

Mar Genomics. 2020 Feb 11:100753. doi: 10.1016/j.margen.2020.100753. [Epub ahead of print]


Transcriptomic analysis of insecticide resistance in the lymphatic filariasis vector Culex quinquefasciatus.

Silva Martins WF, Wilding CS, Isaacs AT, Rippon EJ, Megy K, Donnelly MJ.

Sci Rep. 2019 Aug 6;9(1):11406. doi: 10.1038/s41598-019-47850-w.


Development and application of a tri-allelic PCR assay for screening Vgsc-L1014F kdr mutations associated with pyrethroid and organochlorine resistance in the mosquito Culex quinquefasciatus.

Silva Martins WF, Silva Pereira BN, Vieira Alves AT, Murphy A, Silva Martins PG, Weetman D, Wilding CS, Donnelly MJ.

Parasit Vectors. 2019 May 14;12(1):232. doi: 10.1186/s13071-019-3490-z.


Regulating resistance: CncC:Maf, antioxidant response elements and the overexpression of detoxification genes in insecticide resistance.

Wilding CS.

Curr Opin Insect Sci. 2018 Jun;27:89-96. doi: 10.1016/j.cois.2018.04.006. Epub 2018 Apr 13. Review.


Candidate-gene based GWAS identifies reproducible DNA markers for metabolic pyrethroid resistance from standing genetic variation in East African Anopheles gambiae.

Weetman D, Wilding CS, Neafsey DE, Müller P, Ochomo E, Isaacs AT, Steen K, Rippon EJ, Morgan JC, Mawejje HD, Rigden DJ, Okedi LM, Donnelly MJ.

Sci Rep. 2018 Feb 13;8(1):2920. doi: 10.1038/s41598-018-21265-5.


Local selection in the presence of high levels of gene flow: Evidence of heterogeneous insecticide selection pressure across Ugandan Culex quinquefasciatus populations.

Silva Martins WF, Wilding CS, Steen K, Mawejje H, Antão TR, Donnelly MJ.

PLoS Negl Trop Dis. 2017 Oct 3;11(10):e0005917. doi: 10.1371/journal.pntd.0005917. eCollection 2017 Oct.


Detection and quantitation of copy number variation in the voltage-gated sodium channel gene of the mosquito Culex quinquefasciatus.

Martins WFS, Subramaniam K, Steen K, Mawejje H, Liloglou T, Donnelly MJ, Wilding CS.

Sci Rep. 2017 Jul 19;7(1):5821. doi: 10.1038/s41598-017-06080-8.


Limited genomic divergence between intraspecific forms of Culex pipiens under different ecological pressures.

Gomes B, Wilding CS, Weetman D, Sousa CA, Novo MT, Savage HM, Almeida AP, Pinto J, Donnelly MJ.

BMC Evol Biol. 2015 Sep 16;15:197. doi: 10.1186/s12862-015-0477-z.


Contemporary evolution of resistance at the major insecticide target site gene Ace-1 by mutation and copy number variation in the malaria mosquito Anopheles gambiae.

Weetman D, Mitchell SN, Wilding CS, Birks DP, Yawson AE, Essandoh J, Mawejje HD, Djogbenou LS, Steen K, Rippon EJ, Clarkson CS, Field SG, Rigden DJ, Donnelly MJ.

Mol Ecol. 2015 Jun;24(11):2656-72. doi: 10.1111/mec.13197. Epub 2015 May 14.


Mosquito genomics. Highly evolvable malaria vectors: the genomes of 16 Anopheles mosquitoes.

Neafsey DE, Waterhouse RM, Abai MR, Aganezov SS, Alekseyev MA, Allen JE, Amon J, Arcà B, Arensburger P, Artemov G, Assour LA, Basseri H, Berlin A, Birren BW, Blandin SA, Brockman AI, Burkot TR, Burt A, Chan CS, Chauve C, Chiu JC, Christensen M, Costantini C, Davidson VL, Deligianni E, Dottorini T, Dritsou V, Gabriel SB, Guelbeogo WM, Hall AB, Han MV, Hlaing T, Hughes DS, Jenkins AM, Jiang X, Jungreis I, Kakani EG, Kamali M, Kemppainen P, Kennedy RC, Kirmitzoglou IK, Koekemoer LL, Laban N, Langridge N, Lawniczak MK, Lirakis M, Lobo NF, Lowy E, MacCallum RM, Mao C, Maslen G, Mbogo C, McCarthy J, Michel K, Mitchell SN, Moore W, Murphy KA, Naumenko AN, Nolan T, Novoa EM, O'Loughlin S, Oringanje C, Oshaghi MA, Pakpour N, Papathanos PA, Peery AN, Povelones M, Prakash A, Price DP, Rajaraman A, Reimer LJ, Rinker DC, Rokas A, Russell TL, Sagnon N, Sharakhova MV, Shea T, Simão FA, Simard F, Slotman MA, Somboon P, Stegniy V, Struchiner CJ, Thomas GW, Tojo M, Topalis P, Tubio JM, Unger MF, Vontas J, Walton C, Wilding CS, Willis JH, Wu YC, Yan G, Zdobnov EM, Zhou X, Catteruccia F, Christophides GK, Collins FH, Cornman RS, Crisanti A, Donnelly MJ, Emrich SJ, Fontaine MC, Gelbart W, Hahn MW, Hansen IA, Howell PI, Kafatos FC, Kellis M, Lawson D, Louis C, Luckhart S, Muskavitch MA, Ribeiro JM, Riehle MA, Sharakhov IV, Tu Z, Zwiebel LJ, Besansky NJ.

Science. 2015 Jan 2;347(6217):1258522. doi: 10.1126/science.1258522. Epub 2014 Nov 27.


Parallel evolution or purifying selection, not introgression, explains similarity in the pyrethroid detoxification linked GSTE4 of Anopheles gambiae and An. arabiensis.

Wilding CS, Weetman D, Rippon EJ, Steen K, Mawejje HD, Barsukov I, Donnelly MJ.

Mol Genet Genomics. 2015 Feb;290(1):201-15. doi: 10.1007/s00438-014-0910-9. Epub 2014 Sep 12.


Contemporary gene flow between wild An. gambiae s.s. and An. arabiensis.

Weetman D, Steen K, Rippon EJ, Mawejje HD, Donnelly MJ, Wilding CS.

Parasit Vectors. 2014 Jul 24;7:345. doi: 10.1186/1756-3305-7-345.


Insecticide resistance in Anopheles arabiensis in Sudan: temporal trends and underlying mechanisms.

Abdalla H, Wilding CS, Nardini L, Pignatelli P, Koekemoer LL, Ranson H, Coetzee M.

Parasit Vectors. 2014 May 8;7:213. doi: 10.1186/1756-3305-7-213.


Metabolic and target-site mechanisms combine to confer strong DDT resistance in Anopheles gambiae.

Mitchell SN, Rigden DJ, Dowd AJ, Lu F, Wilding CS, Weetman D, Dadzie S, Jenkins AM, Regna K, Boko P, Djogbenou L, Muskavitch MA, Ranson H, Paine MJ, Mayans O, Donnelly MJ.

PLoS One. 2014 Mar 27;9(3):e92662. doi: 10.1371/journal.pone.0092662. eCollection 2014.


Gene amplification and microsatellite polymorphism underlie a recent insect host shift.

Bass C, Zimmer CT, Riveron JM, Wilding CS, Wondji CS, Kaussmann M, Field LM, Williamson MS, Nauen R.

Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):19460-5. doi: 10.1073/pnas.1314122110. Epub 2013 Nov 11.


Insecticide resistance monitoring of field-collected Anopheles gambiae s.l. populations from Jinja, eastern Uganda, identifies high levels of pyrethroid resistance.

Mawejje HD, Wilding CS, Rippon EJ, Hughes A, Weetman D, Donnelly MJ.

Med Vet Entomol. 2013 Sep;27(3):276-83. doi: 10.1111/j.1365-2915.2012.01055.x. Epub 2012 Oct 10.


A cis-regulatory sequence driving metabolic insecticide resistance in mosquitoes: functional characterisation and signatures of selection.

Wilding CS, Smith I, Lynd A, Yawson AE, Weetman D, Paine MJ, Donnelly MJ.

Insect Biochem Mol Biol. 2012 Sep;42(9):699-707. doi: 10.1016/j.ibmb.2012.06.003. Epub 2012 Jun 23.


Footprints of positive selection associated with a mutation (N1575Y) in the voltage-gated sodium channel of Anopheles gambiae.

Jones CM, Liyanapathirana M, Agossa FR, Weetman D, Ranson H, Donnelly MJ, Wilding CS.

Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6614-9. doi: 10.1073/pnas.1201475109. Epub 2012 Apr 9.


Identification and validation of a gene causing cross-resistance between insecticide classes in Anopheles gambiae from Ghana.

Mitchell SN, Stevenson BJ, Müller P, Wilding CS, Egyir-Yawson A, Field SG, Hemingway J, Paine MJ, Ranson H, Donnelly MJ.

Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):6147-52. doi: 10.1073/pnas.1203452109. Epub 2012 Mar 28.


Comparative genomics of the anopheline glutathione S-transferase epsilon cluster.

Ayres CF, Müller P, Dyer N, Wilding CS, Rigden DJ, Donnelly MJ.

PLoS One. 2011;6(12):e29237. doi: 10.1371/journal.pone.0029237. Epub 2011 Dec 19. Erratum in: PLoS One. 2012;7(1). doi:10.1371/annotation/1dbf46fc-3f3f-47d0-9605-514bda135ba4. Ayres, Constância [corrected to Ayres, Constância F J];Wilding, Craig [corrected to Wilding, Craig S]; Rigden, Daniel [corrected to Rigden, Daniel J]; Donnelly, M [corrected to Donnelly, Martin J ].


Gene flow-dependent genomic divergence between Anopheles gambiae M and S forms.

Weetman D, Wilding CS, Steen K, Pinto J, Donnelly MJ.

Mol Biol Evol. 2012 Jan;29(1):279-91. doi: 10.1093/molbev/msr199. Epub 2011 Aug 11.


The emergence of insecticide resistance in central Mozambique and potential threat to the successful indoor residual spraying malaria control programme.

Abilio AP, Kleinschmidt I, Rehman AM, Cuamba N, Ramdeen V, Mthembu DS, Coetzer S, Maharaj R, Wilding CS, Steven A, Coleman M, Hemingway J, Coleman M.

Malar J. 2011 May 2;10:110. doi: 10.1186/1475-2875-10-110.


Insecticide resistance in Aedes aegypti populations from Ceará, Brazil.

Lima EP, Paiva MH, de Araújo AP, da Silva EV, da Silva UM, de Oliveira LN, Santana AE, Barbosa CN, de Paiva Neto CC, Goulart MO, Wilding CS, Ayres CF, de Melo Santos MA.

Parasit Vectors. 2011 Jan 12;4:5. doi: 10.1186/1756-3305-4-5.


Association mapping of insecticide resistance in wild Anopheles gambiae populations: major variants identified in a low-linkage disequilbrium genome.

Weetman D, Wilding CS, Steen K, Morgan JC, Simard F, Donnelly MJ.

PLoS One. 2010 Oct 1;5(10):e13140. doi: 10.1371/journal.pone.0013140.


Does kdr genotype predict insecticide-resistance phenotype in mosquitoes?

Donnelly MJ, Corbel V, Weetman D, Wilding CS, Williamson MS, Black WC 4th.

Trends Parasitol. 2009 May;25(5):213-9. doi: 10.1016/


Reduced susceptibility to DDT in field populations of Anopheles quadriannulatus and Anopheles arabiensis in Malawi: evidence for larval selection.

Mzilahowa T, Ball AJ, Bass C, Morgan JC, Nyoni B, Steen K, Donnelly MJ, Wilding CS.

Med Vet Entomol. 2008 Sep;22(3):258-63. doi: 10.1111/j.1365-2915.2008.00736.x.


Influence of polymorphisms at loci encoding DNA repair proteins on cancer susceptibility and G2 chromosomal radiosensitivity.

Wilding CS, Curwen GB, Tawn EJ, Sheng X, Winther JF, Chakraborty R, Boice JD Jr.

Environ Mol Mutagen. 2007 Jan;48(1):48-57. Erratum in: Environ Mol Mutagen. 2007 Jul;48(6):502.


Mitochondrial DNA mutations in individuals occupationally exposed to ionizing radiation.

Wilding CS, Cadwell K, Tawn EJ, Relton CL, Taylor GA, Chinnery PF, Turnbull DM.

Radiat Res. 2006 Feb;165(2):202-7.


Mitochondrial DNA mutation frequencies in experimentally irradiated compost worms, Eisenia fetida.

Wilding CS, Trikic MZ, Hingston JL, Copplestone D, Janet Tawn E.

Mutat Res. 2006 Jan 31;603(1):56-63. Epub 2005 Dec 27.


Intron analyses reveal multiple calmodulin copies in Littorina.

Simpson RJ, Wilding CS, Grahame J.

J Mol Evol. 2005 Apr;60(4):505-12.


DNA repair gene polymorphisms in relation to chromosome aberration frequencies in retired radiation workers.

Wilding CS, Relton CL, Rees GS, Tarone RE, Whitehouse CA, Tawn EJ.

Mutat Res. 2005 Feb 15;570(1):137-45.


Thymidylate synthase repeat polymorphisms and risk of neural tube defects in a population from the northern United Kingdom.

Wilding CS, Relton CL, Sutton MJ, Jonas PA, Lynch SA, Tawn EJ, Burn J.

Birth Defects Res A Clin Mol Teratol. 2004 Jul;70(7):483-5.


Gene-gene interaction in folate-related genes and risk of neural tube defects in a UK population.

Relton CL, Wilding CS, Pearce MS, Laffling AJ, Jonas PA, Lynch SA, Tawn EJ, Burn J.

J Med Genet. 2004 Apr;41(4):256-60.


Low erythrocyte folate status and polymorphic variation in folate-related genes are associated with risk of neural tube defect pregnancy.

Relton CL, Wilding CS, Laffling AJ, Jonas PA, Burgess T, Binks K, Tawn EJ, Burn J.

Mol Genet Metab. 2004 Apr;81(4):273-81.


Genetic susceptibility to neural tube defect pregnancy varies with offspring phenotype.

Relton CL, Wilding CS, Jonas PA, Lynch SA, Tawn EJ, Burn J.

Clin Genet. 2003 Nov;64(5):424-8.


Mitochondrial DNA CoI haplotype variation in sibling species of rough periwinkles.

Wilding CS, Grahame J, Mill PJ.

Heredity (Edinb). 2000 Jul;85 ( Pt 1):62-74.


Simple protocol for extracting nuclear DNA from single embryos of a marine snail.

Simpson RJ, Wilding CS, Grahame J.

Biotechniques. 1999 Jun;26(6):1050-2. No abstract available.


Mitochondrial DNA variation in the scallop Pecten maximus (L.) assessed by a PCR-RFLP method.

Wilding CS, Beaumont AR, Latchford JW.

Heredity (Edinb). 1997 Aug;79 ( Pt 2):178-89.

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