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Items: 30


Human Cancer Cell Membrane-Coated Biomimetic Nanoparticles Reduce Fibroblast-Mediated Invasion and Metastasis and Induce T-Cells.

Jin J, Krishnamachary B, Barnett JD, Chatterjee S, Chang D, Mironchik Y, Wildes F, Jaffee EM, Nimmagadda S, Bhujwalla ZM.

ACS Appl Mater Interfaces. 2019 Feb 27;11(8):7850-7861. doi: 10.1021/acsami.8b22309. Epub 2019 Feb 14.


MRI and MRS of intact perfused cancer cell metabolism, invasion, and stromal cell interactions.

Penet MF, Shah T, Wildes F, Krishnamachary B, Bharti SK, Pacheco-Torres J, Artemov D, Bhujwalla ZM.

NMR Biomed. 2019 Jan 28:e4053. doi: 10.1002/nbm.4053. [Epub ahead of print]


Hypoxia Patterns in Primary and Metastatic Prostate Cancer Environments.

Bharti SK, Kakkad S, Danhier P, Wildes F, Penet MF, Krishnamachary B, Bhujwalla ZM.

Neoplasia. 2019 Feb;21(2):239-246. doi: 10.1016/j.neo.2018.12.004. Epub 2019 Jan 10.


Ascites Volumes and the Ovarian Cancer Microenvironment.

Penet MF, Krishnamachary B, Wildes FB, Mironchik Y, Hung CF, Wu TC, Bhujwalla ZM.

Front Oncol. 2018 Dec 17;8:595. doi: 10.3389/fonc.2018.00595. eCollection 2018.


Molecular causes of elevated phosphoethanolamine in breast and pancreatic cancer cells.

Shah T, Krishnamachary B, Wildes F, Wijnen JP, Glunde K, Bhujwalla ZM.

NMR Biomed. 2018 Aug;31(8):e3936. doi: 10.1002/nbm.3936. Epub 2018 Jun 21.


Metabolic consequences of HIF silencing in a triple negative human breast cancer xenograft.

Bharti SK, Mironchik Y, Wildes F, Penet MF, Goggins E, Krishnamachary B, Bhujwalla ZM.

Oncotarget. 2018 Feb 24;9(20):15326-15339. doi: 10.18632/oncotarget.24569. eCollection 2018 Mar 16.


Metabolomic characterization of experimental ovarian cancer ascitic fluid.

Bharti SK, Wildes F, Hung CF, Wu TC, Bhujwalla ZM, Penet MF.

Metabolomics. 2017 Oct;13. pii: 113. doi: 10.1007/s11306-017-1254-3. Epub 2017 Aug 24.


Hypoxia Inducible Factors Modify Collagen I Fibers in MDA-MB-231 Triple Negative Breast Cancer Xenografts.

Goggins E, Kakkad S, Mironchik Y, Jacob D, Wildes F, Krishnamachary B, Bhujwalla ZM.

Neoplasia. 2018 Feb;20(2):131-139. doi: 10.1016/j.neo.2017.11.010. Epub 2017 Dec 13.


Breast cancer cell cyclooxygenase-2 expression alters extracellular matrix structure and function and numbers of cancer associated fibroblasts.

Krishnamachary B, Stasinopoulos I, Kakkad S, Penet MF, Jacob D, Wildes F, Mironchik Y, Pathak AP, Solaiyappan M, Bhujwalla ZM.

Oncotarget. 2017 Mar 14;8(11):17981-17994. doi: 10.18632/oncotarget.14912.


The Tumor Microenvironment Modulates Choline and Lipid Metabolism.

Mori N, Wildes F, Takagi T, Glunde K, Bhujwalla ZM.

Front Oncol. 2016 Dec 22;6:262. doi: 10.3389/fonc.2016.00262. eCollection 2016.


Effect of Pantethine on Ovarian Tumor Progression and Choline Metabolism.

Penet MF, Krishnamachary B, Wildes F, Mironchik Y, Mezzanzanica D, Podo F, de Reggi M, Gharib B, Bhujwalla ZM.

Front Oncol. 2016 Nov 16;6:244. eCollection 2016.


Lymphatic endothelial cells actively regulate prostate cancer cell invasion.

Shah T, Wildes F, Kakkad S, Artemov D, Bhujwalla ZM.

NMR Biomed. 2016 Jul;29(7):904-11. doi: 10.1002/nbm.3543. Epub 2016 May 5.


Detection of Pancreatic Cancer-Induced Cachexia Using a Fluorescent Myoblast Reporter System and Analysis of Metabolite Abundance.

Winnard PT Jr, Bharti SK, Penet MF, Marik R, Mironchik Y, Wildes F, Maitra A, Bhujwalla ZM.

Cancer Res. 2016 Mar 15;76(6):1441-50. doi: 10.1158/0008-5472.CAN-15-1740. Epub 2015 Dec 30.


Choline kinase-α protein and phosphatidylcholine but not phosphocholine are required for breast cancer cell survival.

Mori N, Wildes F, Kakkad S, Jacob D, Solaiyappan M, Glunde K, Bhujwalla ZM.

NMR Biomed. 2015 Dec;28(12):1697-706. doi: 10.1002/nbm.3429. Epub 2015 Oct 27.


HIF isoforms have divergent effects on invasion, metastasis, metabolism and formation of lipid droplets.

Shah T, Krishnamachary B, Wildes F, Mironchik Y, Kakkad SM, Jacob D, Artemov D, Bhujwalla ZM.

Oncotarget. 2015 Sep 29;6(29):28104-19. doi: 10.18632/oncotarget.4612.


Targeting Glutamine Metabolism in Breast Cancer with Aminooxyacetate.

Korangath P, Teo WW, Sadik H, Han L, Mori N, Huijts CM, Wildes F, Bharti S, Zhang Z, Santa-Maria CA, Tsai H, Dang CV, Stearns V, Bhujwalla ZM, Sukumar S.

Clin Cancer Res. 2015 Jul 15;21(14):3263-73. doi: 10.1158/1078-0432.CCR-14-1200. Epub 2015 Mar 26.


Metabolic imaging of pancreatic ductal adenocarcinoma detects altered choline metabolism.

Penet MF, Shah T, Bharti S, Krishnamachary B, Artemov D, Mironchik Y, Wildes F, Maitra A, Bhujwalla ZM.

Clin Cancer Res. 2015 Jan 15;21(2):386-95. doi: 10.1158/1078-0432.CCR-14-0964. Epub 2014 Nov 4.


Characterization of choline kinase in human endothelial cells.

Mori N, Gadiya M, Wildes F, Krishnamachary B, Glunde K, Bhujwalla ZM.

NMR Biomed. 2013 Nov;26(11):1501-7. doi: 10.1002/nbm.2983. Epub 2013 Jun 18.


In vivo "MRI phenotyping" reveals changes in extracellular matrix transport and vascularization that mediate VEGF-driven increase in breast cancer metastasis.

Pathak AP, McNutt S, Shah T, Wildes F, Raman V, Bhujwalla ZM.

PLoS One. 2013 May 1;8(5):e63146. doi: 10.1371/journal.pone.0063146. Print 2013.


Noninvasive imaging identifies new roles for cyclooxygenase-2 in choline and lipid metabolism of human breast cancer cells.

Shah T, Stasinopoulos I, Wildes F, Kakkad S, Artemov D, Bhujwalla ZM.

NMR Biomed. 2012 May;25(5):746-54. doi: 10.1002/nbm.1789. Epub 2011 Sep 22.


The HOXB7 protein renders breast cancer cells resistant to tamoxifen through activation of the EGFR pathway.

Jin K, Kong X, Shah T, Penet MF, Wildes F, Sgroi DC, Ma XJ, Huang Y, Kallioniemi A, Landberg G, Bieche I, Wu X, Lobie PE, Davidson NE, Bhujwalla ZM, Zhu T, Sukumar S.

Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2736-41. doi: 10.1073/pnas.1018859108. Epub 2011 Jun 20.


Nanoplex delivery of siRNA and prodrug enzyme for multimodality image-guided molecular pathway targeted cancer therapy.

Li C, Penet MF, Wildes F, Takagi T, Chen Z, Winnard PT, Artemov D, Bhujwalla ZM.

ACS Nano. 2010 Nov 23;4(11):6707-16. doi: 10.1021/nn102187v. Epub 2010 Oct 19.


Choline kinase overexpression increases invasiveness and drug resistance of human breast cancer cells.

Shah T, Wildes F, Penet MF, Winnard PT Jr, Glunde K, Artemov D, Ackerstaff E, Gimi B, Kakkad S, Raman V, Bhujwalla ZM.

NMR Biomed. 2010 Jul;23(6):633-42. doi: 10.1002/nbm.1510.


Noninvasive detection of lentiviral-mediated choline kinase targeting in a human breast cancer xenograft.

Krishnamachary B, Glunde K, Wildes F, Mori N, Takagi T, Raman V, Bhujwalla ZM.

Cancer Res. 2009 Apr 15;69(8):3464-71. doi: 10.1158/0008-5472.CAN-08-4120. Epub 2009 Mar 31.


Conjugation of poly-L-lysine to bacterial cytosine deaminase improves the efficacy of enzyme/prodrug cancer therapy.

Li C, Wildes F, Winnard P Jr, Artemov D, Penet MF, Bhujwalla ZM.

J Med Chem. 2008 Jun 26;51(12):3572-82. doi: 10.1021/jm800288h. Epub 2008 Jun 3.


Hypoxia increases breast cancer cell-induced lymphatic endothelial cell migration.

Mikhaylova M, Mori N, Wildes FB, Walczak P, Gimi B, Bhujwalla ZM.

Neoplasia. 2008 Apr;10(4):380-9.


Silencing of cyclooxygenase-2 inhibits metastasis and delays tumor onset of poorly differentiated metastatic breast cancer cells.

Stasinopoulos I, O'Brien DR, Wildes F, Glunde K, Bhujwalla ZM.

Mol Cancer Res. 2007 May;5(5):435-42.


Twist overexpression induces in vivo angiogenesis and correlates with chromosomal instability in breast cancer.

Mironchik Y, Winnard PT Jr, Vesuna F, Kato Y, Wildes F, Pathak AP, Kominsky S, Artemov D, Bhujwalla Z, Van Diest P, Burger H, Glackin C, Raman V.

Cancer Res. 2005 Dec 1;65(23):10801-9.


Synthesis of 6'-O-lissamine-rhodamine B-glucosamine as a novel probe for fluorescence imaging of lysosomes in breast tumors.

Glunde K, Foss CA, Takagi T, Wildes F, Bhujwalla ZM.

Bioconjug Chem. 2005 Jul-Aug;16(4):843-51.


HOXA5-twist interaction alters p53 homeostasis in breast cancer cells.

Stasinopoulos IA, Mironchik Y, Raman A, Wildes F, Winnard P Jr, Raman V.

J Biol Chem. 2005 Jan 21;280(3):2294-9. Epub 2004 Nov 15.

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