Sort by
Items per page

Send to

Choose Destination

Search results

Items: 22


IA-Lab: A MATLAB framework for efficient microscopy image analysis development, applied to quantifying intracellular transport of internalized peptide-drug conjugate.

Corrigan AM, Karlsson J, Wildenhain J, Knerr L, Ölwegård-Halvarsson M, Karlsson M, Lünse S, Wang Y.

PLoS One. 2019 Aug 1;14(8):e0220627. doi: 10.1371/journal.pone.0220627. eCollection 2019.


onlineFDR: an R package to control the false discovery rate for growing data repositories.

Robertson DS, Wildenhain J, Javanmard A, Karp NA.

Bioinformatics. 2019 Mar 14. pii: btz191. doi: 10.1093/bioinformatics/btz191. [Epub ahead of print]


Systematic chemical-genetic and chemical-chemical interaction datasets for prediction of compound synergism.

Wildenhain J, Spitzer M, Dolma S, Jarvik N, White R, Roy M, Griffiths E, Bellows DS, Wright GD, Tyers M.

Sci Data. 2016 Nov 22;3:160095. doi: 10.1038/sdata.2016.95.


Effects of Air Temperature on Climate-Sensitive Mortality and Morbidity Outcomes in the Elderly; a Systematic Review and Meta-analysis of Epidemiological Evidence.

Bunker A, Wildenhain J, Vandenbergh A, Henschke N, Rocklöv J, Hajat S, Sauerborn R.

EBioMedicine. 2016 Apr;6:258-268. doi: 10.1016/j.ebiom.2016.02.034. Epub 2016 Feb 23. Review.


Prediction of Synergism from Chemical-Genetic Interactions by Machine Learning.

Wildenhain J, Spitzer M, Dolma S, Jarvik N, White R, Roy M, Griffiths E, Bellows DS, Wright GD, Tyers M.

Cell Syst. 2015 Dec 23;1(6):383-95. doi: 10.1016/j.cels.2015.12.003. Epub 2015 Dec 23.


A loss of function analysis of host factors influencing Vaccinia virus replication by RNA interference.

Beard PM, Griffiths SJ, Gonzalez O, Haga IR, Pechenick Jowers T, Reynolds DK, Wildenhain J, Tekotte H, Auer M, Tyers M, Ghazal P, Zimmer R, Haas J.

PLoS One. 2014 Jun 5;9(6):e98431. doi: 10.1371/journal.pone.0098431. eCollection 2014.


BoxPlotR: a web tool for generation of box plots.

Spitzer M, Wildenhain J, Rappsilber J, Tyers M.

Nat Methods. 2014 Feb;11(2):121-2. doi: 10.1038/nmeth.2811. No abstract available.


A role for intracellular calcium downstream of G-protein signaling in undifferentiated human embryonic stem cell culture.

Ermakov A, Pells S, Freile P, Ganeva VV, Wildenhain J, Bradley M, Pawson A, Millar R, De Sousa PA.

Stem Cell Res. 2012 Nov;9(3):171-84. doi: 10.1016/j.scr.2012.06.007. Epub 2012 Jul 5.


MolClass: a web portal to interrogate diverse small molecule screen datasets with different computational models.

Wildenhain J, Fitzgerald N, Tyers M.

Bioinformatics. 2012 Aug 15;28(16):2200-1. doi: 10.1093/bioinformatics/bts349. Epub 2012 Jun 17.


Characterizing the roles of Met31 and Met32 in coordinating Met4-activated transcription in the absence of Met30.

Carrillo E, Ben-Ari G, Wildenhain J, Tyers M, Grammentz D, Lee TA.

Mol Biol Cell. 2012 May;23(10):1928-42. doi: 10.1091/mbc.E11-06-0532. Epub 2012 Mar 21.


Cross-species discovery of syncretic drug combinations that potentiate the antifungal fluconazole.

Spitzer M, Griffiths E, Blakely KM, Wildenhain J, Ejim L, Rossi L, De Pascale G, Curak J, Brown E, Tyers M, Wright GD.

Mol Syst Biol. 2011 Jun 21;7:499. doi: 10.1038/msb.2011.31.


Combinations of antibiotics and nonantibiotic drugs enhance antimicrobial efficacy.

Ejim L, Farha MA, Falconer SB, Wildenhain J, Coombes BK, Tyers M, Brown ED, Wright GD.

Nat Chem Biol. 2011 Jun;7(6):348-50. doi: 10.1038/nchembio.559. Epub 2011 Apr 24.


BioGRID REST Service, BiogridPlugin2 and BioGRID WebGraph: new tools for access to interaction data at BioGRID.

Winter AG, Wildenhain J, Tyers M.

Bioinformatics. 2011 Apr 1;27(7):1043-4. doi: 10.1093/bioinformatics/btr062. Epub 2011 Feb 7.


The MMS22L-TONSL complex mediates recovery from replication stress and homologous recombination.

O'Donnell L, Panier S, Wildenhain J, Tkach JM, Al-Hakim A, Landry MC, Escribano-Diaz C, Szilard RK, Young JT, Munro M, Canny MD, Kolas NK, Zhang W, Harding SM, Ylanko J, Mendez M, Mullin M, Sun T, Habermann B, Datti A, Bristow RG, Gingras AC, Tyers MD, Brown GW, Durocher D.

Mol Cell. 2010 Nov 24;40(4):619-31. doi: 10.1016/j.molcel.2010.10.024. Epub 2010 Nov 4.


Combined zebrafish-yeast chemical-genetic screens reveal gene-copper-nutrition interactions that modulate melanocyte pigmentation.

Ishizaki H, Spitzer M, Wildenhain J, Anastasaki C, Zeng Z, Dolma S, Shaw M, Madsen E, Gitlin J, Marais R, Tyers M, Patton EE.

Dis Model Mech. 2010 Sep-Oct;3(9-10):639-51. doi: 10.1242/dmm.005769. Epub 2010 Aug 16.


A predictive model for drug bioaccumulation and bioactivity in Caenorhabditis elegans.

Burns AR, Wallace IM, Wildenhain J, Tyers M, Giaever G, Bader GD, Nislow C, Cutler SR, Roy PJ.

Nat Chem Biol. 2010 Jul;6(7):549-57. doi: 10.1038/nchembio.380. Epub 2010 May 30.


The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage.

Stewart GS, Panier S, Townsend K, Al-Hakim AK, Kolas NK, Miller ES, Nakada S, Ylanko J, Olivarius S, Mendez M, Oldreive C, Wildenhain J, Tagliaferro A, Pelletier L, Taubenheim N, Durandy A, Byrd PJ, Stankovic T, Taylor AM, Durocher D.

Cell. 2009 Feb 6;136(3):420-34. doi: 10.1016/j.cell.2008.12.042.


Off-target effects of psychoactive drugs revealed by genome-wide assays in yeast.

Ericson E, Gebbia M, Heisler LE, Wildenhain J, Tyers M, Giaever G, Nislow C.

PLoS Genet. 2008 Aug 8;4(8):e1000151. doi: 10.1371/journal.pgen.1000151.


The chemical genomic portrait of yeast: uncovering a phenotype for all genes.

Hillenmeyer ME, Fung E, Wildenhain J, Pierce SE, Hoon S, Lee W, Proctor M, St Onge RP, Tyers M, Koller D, Altman RB, Davis RW, Nislow C, Giaever G.

Science. 2008 Apr 18;320(5874):362-5. doi: 10.1126/science.1150021.


Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase.

Kolas NK, Chapman JR, Nakada S, Ylanko J, Chahwan R, Sweeney FD, Panier S, Mendez M, Wildenhain J, Thomson TM, Pelletier L, Jackson SP, Durocher D.

Science. 2007 Dec 7;318(5856):1637-40. Epub 2007 Nov 15.


Chemical genetics reveals a complex functional ground state of neural stem cells.

Diamandis P, Wildenhain J, Clarke ID, Sacher AG, Graham J, Bellows DS, Ling EK, Ward RJ, Jamieson LG, Tyers M, Dirks PB.

Nat Chem Biol. 2007 May;3(5):268-73. Epub 2007 Apr 8.


Reconstructing gene regulatory networks: from random to scale-free connectivity.

Wildenhain J, Crampin EJ.

Syst Biol (Stevenage). 2006 Jul;153(4):247-56.


Supplemental Content

Loading ...
Support Center