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Items: 1 to 50 of 303

1.

Bone morphogenetic proteins - 7 and - 2 in the treatment of delayed osseous union secondary to bacterial osteitis in a rat model.

Helbig L, Omlor GW, Ivanova A, Guehring T, Sonntag R, Kretzer JP, Minkwitz S, Wildemann B, Schmidmaier G.

BMC Musculoskelet Disord. 2018 Jul 27;19(1):261. doi: 10.1186/s12891-018-2203-7.

2.

Gd contrast administration is dispensable in patients with MS without new T2 lesions on follow-up MRI.

Karimian-Jazi K, Wildemann B, Diem R, Schwarz D, Hielscher T, Wick W, Bendszus M, Breckwoldt MO.

Neurol Neuroimmunol Neuroinflamm. 2018 Jul 16;5(5):e480. doi: 10.1212/NXI.0000000000000480. eCollection 2018 Sep.

3.

MOG encephalomyelitis: international recommendations on diagnosis and antibody testing.

Jarius S, Paul F, Aktas O, Asgari N, Dale RC, de Seze J, Franciotta D, Fujihara K, Jacob A, Kim HJ, Kleiter I, Kümpfel T, Levy M, Palace J, Ruprecht K, Saiz A, Trebst C, Weinshenker BG, Wildemann B.

J Neuroinflammation. 2018 May 3;15(1):134. doi: 10.1186/s12974-018-1144-2. Review.

4.

The role of cuticular hydrocarbons in mate recognition in Drosophila suzukii.

Snellings Y, Herrera B, Wildemann B, Beelen M, Zwarts L, Wenseleers T, Callaerts P.

Sci Rep. 2018 Mar 22;8(1):4996. doi: 10.1038/s41598-018-23189-6.

5.

MOG-IgG in primary and secondary chronic progressive multiple sclerosis: a multicenter study of 200 patients and review of the literature.

Jarius S, Ruprecht K, Stellmann JP, Huss A, Ayzenberg I, Willing A, Trebst C, Pawlitzki M, Abdelhak A, Grüter T, Leypoldt F, Haas J, Kleiter I, Tumani H, Fechner K, Reindl M, Paul F, Wildemann B.

J Neuroinflammation. 2018 Mar 19;15(1):88. doi: 10.1186/s12974-018-1108-6.

6.

Autoimmune and immunogenetic profile of patients with optic neuritis in a population-based cohort.

Soelberg K, Nilsson AC, Nielsen C, Jarius S, Reindl M, Wildemann B, Lillevang ST, Asgari N.

Mult Scler Relat Disord. 2018 Apr;21:97-102. doi: 10.1016/j.msard.2018.03.003. Epub 2018 Mar 7.

PMID:
29544193
7.

Treatment choices and neuropsychological symptoms of a large cohort of early MS.

von Bismarck O, Dankowski T, Ambrosius B, Hessler N, Antony G, Ziegler A, Hoshi MM, Aly L, Luessi F, Groppa S, Klotz L, Meuth SG, Tackenberg B, Stoppe M, Then Bergh F, Tumani H, Kümpfel T, Stangel M, Heesen C, Wildemann B, Paul F, Bayas A, Warnke C, Weber F, Linker RA, Ziemann U, Zettl UK, Zipp F, Wiendl H, Hemmer B, Gold R, Salmen A.

Neurol Neuroimmunol Neuroinflamm. 2018 Mar 1;5(3):e446. doi: 10.1212/NXI.0000000000000446. eCollection 2018 May.

8.

Different Achilles Tendon Pathologies Show Distinct Histological and Molecular Characteristics.

Klatte-Schulz F, Minkwitz S, Schmock A, Bormann N, Kurtoglu A, Tsitsilonis S, Manegold S, Wildemann B.

Int J Mol Sci. 2018 Jan 30;19(2). pii: E404. doi: 10.3390/ijms19020404.

9.

Baló's concentric sclerosis is immunologically distinct from multiple sclerosis: results from retrospective analysis of almost 150 lumbar punctures.

Jarius S, Würthwein C, Behrens JR, Wanner J, Haas J, Paul F, Wildemann B.

J Neuroinflammation. 2018 Jan 18;15(1):22. doi: 10.1186/s12974-017-1043-y.

10.

Comparative Analysis of Different Platelet Lysates and Platelet Rich Preparations to Stimulate Tendon Cell Biology: An In Vitro Study.

Klatte-Schulz F, Schmidt T, Uckert M, Scheffler S, Kalus U, Rojewski M, Schrezenmeier H, Pruss A, Wildemann B.

Int J Mol Sci. 2018 Jan 10;19(1). pii: E212. doi: 10.3390/ijms19010212.

11.

Magnetic resonance imaging findings at the first episode of acute optic neuritis.

Soelberg K, Skejoe HPB, Grauslund J, Smith TJ, Lillevang ST, Jarius S, Wildemann B, Paul F, Asgari N.

Mult Scler Relat Disord. 2018 Feb;20:30-36. doi: 10.1016/j.msard.2017.12.018. Epub 2017 Dec 25.

PMID:
29291481
12.

Low intrathecal antibody production despite high seroprevalence of Epstein-Barr virus in multiple sclerosis: a review of the literature.

Ruprecht K, Wildemann B, Jarius S.

J Neurol. 2018 Feb;265(2):239-252. doi: 10.1007/s00415-017-8656-z. Epub 2017 Nov 2. Review.

PMID:
29098417
13.

Time-Dependent Alterations of MMPs, TIMPs and Tendon Structure in Human Achilles Tendons after Acute Rupture.

Minkwitz S, Schmock A, Kurtoglu A, Tsitsilonis S, Manegold S, Wildemann B, Klatte-Schulz F.

Int J Mol Sci. 2017 Oct 20;18(10). pii: E2199. doi: 10.3390/ijms18102199.

14.

Peripheral nerve involvement in multiple sclerosis: Demonstration by magnetic resonance neurography.

Jende JME, Hauck GH, Diem R, Weiler M, Heiland S, Wildemann B, Korporal-Kuhnke M, Wick W, Hayes JM, Pfaff J, Pham M, Bendszus M, Kollmer J.

Ann Neurol. 2017 Nov;82(5):676-685. doi: 10.1002/ana.25068. Epub 2017 Oct 26.

PMID:
29023976
15.

Neuromyelitis optica spectrum disorders with antibodies to myelin oligodendrocyte glycoprotein or aquaporin-4: Clinical and paraclinical characteristics in Algerian patients.

Bouzar M, Daoudi S, Hattab S, Bouzar AA, Deiva K, Wildemann B, Reindl M, Jarius S.

J Neurol Sci. 2017 Oct 15;381:240-244. doi: 10.1016/j.jns.2017.08.3254. Epub 2017 Aug 31.

PMID:
28991690
16.

A population-based prospective study of optic neuritis.

Soelberg K, Jarius S, Skejoe H, Engberg H, Mehlsen JJ, Nilsson AC, Madsen JS, Reindl M, Wildemann B, Grauslund J, Kyvik KO, Smith TJ, Lillevang ST, Paul F, Weinshenker BG, Asgari N.

Mult Scler. 2017 Dec;23(14):1893-1901. doi: 10.1177/1352458517734070. Epub 2017 Oct 5.

PMID:
28980518
17.

New insights into tenocyte-immune cell interplay in an in vitro model of inflammation.

Stolk M, Klatte-Schulz F, Schmock A, Minkwitz S, Wildemann B, Seifert M.

Sci Rep. 2017 Aug 29;7(1):9801. doi: 10.1038/s41598-017-09875-x.

18.

Pattern II and pattern III MS are entities distinct from pattern I MS: evidence from cerebrospinal fluid analysis.

Jarius S, König FB, Metz I, Ruprecht K, Paul F, Brück W, Wildemann B.

J Neuroinflammation. 2017 Aug 29;14(1):171. doi: 10.1186/s12974-017-0929-z.

19.

Devic's disease before Devic: On the contribution of Friedrich Albin Schanz (1863-1923).

Jarius S, Wildemann B.

J Neurol Sci. 2017 Aug 15;379:99-102. doi: 10.1016/j.jns.2017.05.044. Epub 2017 May 23.

PMID:
28716289
20.

Aquaporin-4 antibodies in patients treated with natalizumab for suspected MS.

Gahlen A, Trampe AK, Haupeltshofer S, Ringelstein M, Aktas O, Berthele A, Wildemann B, Gold R, Jarius S, Kleiter I.

Neurol Neuroimmunol Neuroinflamm. 2017 Jun 16;4(4):e363. doi: 10.1212/NXI.0000000000000363. eCollection 2017 Jul.

21.

From dizziness to severe ataxia and dysarthria: New cases of anti-Ca/ARHGAP26 autoantibody-associated cerebellar ataxia suggest a broad clinical spectrum.

Wallwitz U, Brock S, Schunck A, Wildemann B, Jarius S, Hoffmann F.

J Neuroimmunol. 2017 Aug 15;309:77-81. doi: 10.1016/j.jneuroim.2017.05.011. Epub 2017 May 22.

PMID:
28601293
22.

Failure of alemtuzumab therapy to control MOG encephalomyelitis.

Wildemann B, Jarius S, Schwarz A, Diem R, Viehöver A, Hähnel S, Reindl M, Korporal-Kuhnke M.

Neurology. 2017 Jul 11;89(2):207-209. doi: 10.1212/WNL.0000000000004087. Epub 2017 Jun 9. No abstract available.

PMID:
28600462
23.

Immunotherapies in neuromyelitis optica spectrum disorder: efficacy and predictors of response.

Stellmann JP, Krumbholz M, Friede T, Gahlen A, Borisow N, Fischer K, Hellwig K, Pache F, Ruprecht K, Havla J, Kümpfel T, Aktas O, Hartung HP, Ringelstein M, Geis C, Kleinschnitz C, Berthele A, Hemmer B, Angstwurm K, Young KL, Schuster S, Stangel M, Lauda F, Tumani H, Mayer C, Zeltner L, Ziemann U, Linker RA, Schwab M, Marziniak M, Then Bergh F, Hofstadt-van Oy U, Neuhaus O, Zettl U, Faiss J, Wildemann B, Paul F, Jarius S, Trebst C, Kleiter I; NEMOS (Neuromyelitis Optica Study Group).

J Neurol Neurosurg Psychiatry. 2017 Aug;88(8):639-647. doi: 10.1136/jnnp-2017-315603. Epub 2017 Jun 1.

24.

Pavlov's Reflex before Pavlov: Early Accounts from the English, French and German Classic Literature.

Jarius S, Wildemann B.

Eur Neurol. 2017;77(5-6):322-326. doi: 10.1159/000475811. Epub 2017 May 25.

25.

A short artificial antimicrobial peptide shows potential to prevent or treat bone infections.

Bormann N, Koliszak A, Kasper S, Schoen L, Hilpert K, Volkmer R, Kikhney J, Wildemann B.

Sci Rep. 2017 May 4;7(1):1506. doi: 10.1038/s41598-017-01698-0.

26.

[Neuromyelitis optica].

Pache F, Wildemann B, Paul F, Jarius S.

Fortschr Neurol Psychiatr. 2017 Feb;85(2):e1. doi: 10.1055/s-0035-1567186. Epub 2017 Apr 5. German. No abstract available.

PMID:
28380640
27.

* Demineralized Bone Matrix as a Carrier for Bone Morphogenetic Protein-2: Burst Release Combined with Long-Term Binding and Osteoinductive Activity Evaluated In Vitro and In Vivo.

Huber E, Pobloth AM, Bormann N, Kolarczik N, Schmidt-Bleek K, Schell H, Schwabe P, Duda GN, Wildemann B.

Tissue Eng Part A. 2017 Dec;23(23-24):1321-1330. doi: 10.1089/ten.TEA.2017.0005. Epub 2017 Apr 28.

PMID:
28351338
28.

[Neuromyelitis optica].

Pache F, Wildemann B, Paul F, Jarius S.

Fortschr Neurol Psychiatr. 2017 Feb;85(2):100-114. doi: 10.1055/s-0042-124186. Epub 2017 Feb 24. Review. German.

PMID:
28235212
29.

Diagnostic criteria for Susac syndrome.

Kleffner I, Dörr J, Ringelstein M, Gross CC, Böckenfeld Y, Schwindt W, Sundermann B, Lohmann H, Wersching H, Promesberger J, von Königsmarck N, Alex A, Guthoff R, Frijns CJ, Kappelle LJ, Jarius S, Wildemann B, Aktas O, Paul F, Wiendl H, Duning T; European Susac Consortium (EuSaC).

J Neurol Neurosurg Psychiatry. 2016 Dec;87(12):1287-1295. doi: 10.1136/jnnp-2016-314295. Epub 2016 Oct 25. Review.

PMID:
28103199
30.

B-cell populations discriminate between pediatric- and adult-onset multiple sclerosis.

Schwarz A, Balint B, Korporal-Kuhnke M, Jarius S, von Engelhardt K, Fürwentsches A, Bussmann C, Ebinger F, Wildemann B, Haas J.

Neurol Neuroimmunol Neuroinflamm. 2016 Dec 15;4(1):e309. doi: 10.1212/NXI.0000000000000309. eCollection 2017 Jan.

31.

Treatment of Tibial Non-Unions - State of the Art and Future Implications.

Märdian S, Giesecke M, Haschke F, Tsitsilonis S, Wildemann B, Schwabe P.

Acta Chir Orthop Traumatol Cech. 2016;83(6):367-374. Review.

PMID:
28026731
32.

The MRZ reaction as a highly specific marker of multiple sclerosis: re-evaluation and structured review of the literature.

Jarius S, Eichhorn P, Franciotta D, Petereit HF, Akman-Demir G, Wick M, Wildemann B.

J Neurol. 2017 Mar;264(3):453-466. doi: 10.1007/s00415-016-8360-4. Epub 2016 Dec 22. Review.

PMID:
28005176
33.

Increasing the sensitivity of MRI for the detection of multiple sclerosis lesions by long axial coverage of the spinal cord: a prospective study in 119 patients.

Breckwoldt MO, Gradl J, Hähnel S, Hielscher T, Wildemann B, Diem R, Platten M, Wick W, Heiland S, Bendszus M.

J Neurol. 2017 Feb;264(2):341-349. doi: 10.1007/s00415-016-8353-3. Epub 2016 Dec 1.

PMID:
27909801
34.

[Importance of cerebrospinal fluid diagnostics in neuropsychiatric diseases].

Tumani H, Uhr M, Wildemann B, Wick M.

Nervenarzt. 2016 Dec;87(12):1259-1260. German. No abstract available.

PMID:
27853851
35.

[Autoantibody-associated autoimmune encephalitis and cerebellitis : Clinical presentation, diagnostic work-up and treatment].

Lewerenz J, Jarius S, Wildemann B, Wandinger KP, Leypoldt F.

Nervenarzt. 2016 Dec;87(12):1293-1299. Review. German.

PMID:
27847964
36.

Myeloid dendritic cells exhibit defects in activation and function in patients with multiple sclerosis.

Haas J, Schwarz A, Korporal-Kuhnke M, Jarius S, Wildemann B.

J Neuroimmunol. 2016 Dec 15;301:53-60. doi: 10.1016/j.jneuroim.2016.10.007. Epub 2016 Nov 2.

PMID:
27836182
37.

MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 3: Brainstem involvement - frequency, presentation and outcome.

Jarius S, Kleiter I, Ruprecht K, Asgari N, Pitarokoili K, Borisow N, Hümmert MW, Trebst C, Pache F, Winkelmann A, Beume LA, Ringelstein M, Stich O, Aktas O, Korporal-Kuhnke M, Schwarz A, Lukas C, Haas J, Fechner K, Buttmann M, Bellmann-Strobl J, Zimmermann H, Brandt AU, Franciotta D, Schanda K, Paul F, Reindl M, Wildemann B; in cooperation with the Neuromyelitis Optica Study Group (NEMOS).

J Neuroinflammation. 2016 Nov 1;13(1):281.

38.

MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 4: Afferent visual system damage after optic neuritis in MOG-IgG-seropositive versus AQP4-IgG-seropositive patients.

Pache F, Zimmermann H, Mikolajczak J, Schumacher S, Lacheta A, Oertel FC, Bellmann-Strobl J, Jarius S, Wildemann B, Reindl M, Waldman A, Soelberg K, Asgari N, Ringelstein M, Aktas O, Gross N, Buttmann M, Ach T, Ruprecht K, Paul F, Brandt AU; in cooperation with the Neuromyelitis Optica Study Group (NEMOS).

J Neuroinflammation. 2016 Nov 1;13(1):282.

39.

MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 2: Epidemiology, clinical presentation, radiological and laboratory features, treatment responses, and long-term outcome.

Jarius S, Ruprecht K, Kleiter I, Borisow N, Asgari N, Pitarokoili K, Pache F, Stich O, Beume LA, Hümmert MW, Ringelstein M, Trebst C, Winkelmann A, Schwarz A, Buttmann M, Zimmermann H, Kuchling J, Franciotta D, Capobianco M, Siebert E, Lukas C, Korporal-Kuhnke M, Haas J, Fechner K, Brandt AU, Schanda K, Aktas O, Paul F, Reindl M, Wildemann B; in cooperation with the Neuromyelitis Optica Study Group (NEMOS).

J Neuroinflammation. 2016 Sep 27;13(1):280.

40.

MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 1: Frequency, syndrome specificity, influence of disease activity, long-term course, association with AQP4-IgG, and origin.

Jarius S, Ruprecht K, Kleiter I, Borisow N, Asgari N, Pitarokoili K, Pache F, Stich O, Beume LA, Hümmert MW, Trebst C, Ringelstein M, Aktas O, Winkelmann A, Buttmann M, Schwarz A, Zimmermann H, Brandt AU, Franciotta D, Capobianco M, Kuchling J, Haas J, Korporal-Kuhnke M, Lillevang ST, Fechner K, Schanda K, Paul F, Wildemann B, Reindl M; in cooperation with the Neuromyelitis Optica Study Group (NEMOS).

J Neuroinflammation. 2016 Sep 26;13(1):279.

41.

Inositol 1,4,5-trisphosphate receptor type 1 autoantibodies in paraneoplastic and non-paraneoplastic peripheral neuropathy.

Jarius S, Ringelstein M, Haas J, Serysheva II, Komorowski L, Fechner K, Wandinger KP, Albrecht P, Hefter H, Moser A, Neuen-Jacob E, Hartung HP, Wildemann B, Aktas O.

J Neuroinflammation. 2016 Oct 24;13(1):278.

42.

Influence of female sex and fertile age on neuromyelitis optica spectrum disorders.

Borisow N, Kleiter I, Gahlen A, Fischer K, Wernecke KD, Pache F, Ruprecht K, Havla J, Krumbholz M, Kümpfel T, Aktas O, Ringelstein M, Geis C, Kleinschnitz C, Berthele A, Hemmer B, Angstwurm K, Weissert R, Stellmann JP, Schuster S, Stangel M, Lauda F, Tumani H, Mayer C, Zeltner L, Ziemann U, Linker RA, Schwab M, Marziniak M, Then Bergh F, Hofstadt-van Oy U, Neuhaus O, Winkelmann A, Marouf W, Rückriem L, Faiss J, Wildemann B, Paul F, Jarius S, Trebst C, Hellwig K; NEMOS (Neuromyelitis Optica Study Group).

Mult Scler. 2017 Jul;23(8):1092-1103. doi: 10.1177/1352458516671203. Epub 2016 Oct 6.

PMID:
27758954
43.

Importance of cerebrospinal fluid analysis in the era of McDonald 2010 criteria: a German-Austrian retrospective multicenter study in patients with a clinically isolated syndrome.

Huss AM, Halbgebauer S, Öckl P, Trebst C, Spreer A, Borisow N, Harrer A, Brecht I, Balint B, Stich O, Schlegel S, Retzlaff N, Winkelmann A, Roesler R, Lauda F, Yildiz Ö, Voß E, Muche R, Rauer S, Bergh FT, Otto M, Paul F, Wildemann B, Kraus J, Ruprecht K, Stangel M, Buttmann M, Zettl UK, Tumani H.

J Neurol. 2016 Dec;263(12):2499-2504. Epub 2016 Oct 11.

44.

Sodium MRI in Multiple Sclerosis is Compatible with Intracellular Sodium Accumulation and Inflammation-Induced Hyper-Cellularity of Acute Brain Lesions.

Biller A, Pflugmann I, Badde S, Diem R, Wildemann B, Nagel AM, Jordan J, Benkhedah N, Kleesiek J.

Sci Rep. 2016 Aug 10;6:31269. doi: 10.1038/srep31269.

45.

An investigation of BMP-7 mediated alterations to BMP signalling components in human tenocyte-like cells.

Klatte-Schulz F, Giese G, Differ C, Minkwitz S, Ruschke K, Puts R, Knaus P, Wildemann B.

Sci Rep. 2016 Jul 11;6:29703. doi: 10.1038/srep29703.

46.

Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation.

Andlauer TF, Buck D, Antony G, Bayas A, Bechmann L, Berthele A, Chan A, Gasperi C, Gold R, Graetz C, Haas J, Hecker M, Infante-Duarte C, Knop M, Kümpfel T, Limmroth V, Linker RA, Loleit V, Luessi F, Meuth SG, Mühlau M, Nischwitz S, Paul F, Pütz M, Ruck T, Salmen A, Stangel M, Stellmann JP, Stürner KH, Tackenberg B, Then Bergh F, Tumani H, Warnke C, Weber F, Wiendl H, Wildemann B, Zettl UK, Ziemann U, Zipp F, Arloth J, Weber P, Radivojkov-Blagojevic M, Scheinhardt MO, Dankowski T, Bettecken T, Lichtner P, Czamara D, Carrillo-Roa T, Binder EB, Berger K, Bertram L, Franke A, Gieger C, Herms S, Homuth G, Ising M, Jöckel KH, Kacprowski T, Kloiber S, Laudes M, Lieb W, Lill CM, Lucae S, Meitinger T, Moebus S, Müller-Nurasyid M, Nöthen MM, Petersmann A, Rawal R, Schminke U, Strauch K, Völzke H, Waldenberger M, Wellmann J, Porcu E, Mulas A, Pitzalis M, Sidore C, Zara I, Cucca F, Zoledziewska M, Ziegler A, Hemmer B, Müller-Myhsok B.

Sci Adv. 2016 Jun 17;2(6):e1501678. doi: 10.1126/sciadv.1501678. eCollection 2016 Jun.

47.

Adding Papillomacular Bundle Measurements to Standard Optical Coherence Tomography Does Not Increase Sensitivity to Detect Prior Optic Neuritis in Patients with Multiple Sclerosis.

Laible M, Jarius S, Mackensen F, Schmidt-Bacher A, Platten M, Haas J, Albrecht P, Wildemann B.

PLoS One. 2016 May 12;11(5):e0155322. doi: 10.1371/journal.pone.0155322. eCollection 2016.

48.

Hypovitaminosis D upscales B-cell immunoreactivity in multiple sclerosis.

Haas J, Schwarz A, Korporal-Kuhnke M, Faller S, Jarius S, Wildemann B.

J Neuroimmunol. 2016 May 15;294:18-26. doi: 10.1016/j.jneuroim.2016.03.011. Epub 2016 Mar 23.

PMID:
27138094
49.

Multicentre comparison of a diagnostic assay: aquaporin-4 antibodies in neuromyelitis optica.

Waters P, Reindl M, Saiz A, Schanda K, Tuller F, Kral V, Nytrova P, Sobek O, Nielsen HH, Barington T, Lillevang ST, Illes Z, Rentzsch K, Berthele A, Berki T, Granieri L, Bertolotto A, Giometto B, Zuliani L, Hamann D, van Pelt ED, Hintzen R, Höftberger R, Costa C, Comabella M, Montalban X, Tintoré M, Siva A, Altintas A, Deniz G, Woodhall M, Palace J, Paul F, Hartung HP, Aktas O, Jarius S, Wildemann B, Vedeler C, Ruiz A, Leite MI, Trillenberg P, Probst M, Saschenbrecker S, Vincent A, Marignier R.

J Neurol Neurosurg Psychiatry. 2016 Sep;87(9):1005-15. doi: 10.1136/jnnp-2015-312601. Epub 2016 Apr 25.

50.

Prevalence of neurofascin-155 antibodies in patients with multiple sclerosis.

Stich O, Perera S, Berger B, Jarius S, Wildemann B, Baumgartner A, Rauer S.

J Neurol Sci. 2016 May 15;364:29-32. doi: 10.1016/j.jns.2016.03.004. Epub 2016 Mar 3.

PMID:
27084211

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