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NaHCO3 Dilates Mouse Afferent Arteriole Via Na+/HCO3- Cotransporters NBCs.

Jiang S, Wang X, Wei J, Zhang G, Zhang J, Xie P, Xu L, Wang L, Zhao L, Li L, Wilcox CS, Chen J, Lai EY, Liu R.

Hypertension. 2019 Sep 16:HYPERTENSIONAHA11913235. doi: 10.1161/HYPERTENSIONAHA.119.13235. [Epub ahead of print]


Adipocytes initiate an adipose-cerebral-peripheral sympathetic reflex to induce insulin resistance during high-fat feeding.

Cao W, Shi M, Wu L, Li J, Yang Z, Liu Y, Wilcox CS, Hou FF.

Clin Sci (Lond). 2019 Sep 10;133(17):1883-1899. doi: 10.1042/CS20190412. Print 2019 Sep 13.


Endothelin-1-Induced Microvascular ROS and Contractility in Angiotensin-II-Infused Mice Depend on COX and TP Receptors.

Wilcox CS, Wang C, Wang D.

Antioxidants (Basel). 2019 Jun 22;8(6). pii: E193. doi: 10.3390/antiox8060193.


A Molecular Torsion Balance Study: A Nearby Anionic Group Exerts Little Influence on Hydrophobic Interactions between Nonpolar Surfaces.

Ling X, Wilcox CS.

Chemistry. 2019 Mar 26. doi: 10.1002/chem.201901208. [Epub ahead of print]


A renal-cerebral-peripheral sympathetic reflex mediates insulin resistance in chronic kidney disease.

Cao W, Shi M, Wu L, Yang Z, Yang X, Liu H, Xu X, Liu Y, Wilcox CS, Hou FF.

EBioMedicine. 2018 Nov;37:281-293. doi: 10.1016/j.ebiom.2018.10.054. Epub 2018 Nov 11.


Fibroblast Growth Factor Binding Protein 3 (FGFBP3) impacts carbohydrate and lipid metabolism.

Tassi E, Garman KA, Schmidt MO, Ma X, Kabbara KW, Uren A, Tomita Y, Goetz R, Mohammadi M, Wilcox CS, Riegel AT, Carlstrom M, Wellstein A.

Sci Rep. 2018 Oct 29;8(1):15973. doi: 10.1038/s41598-018-34238-5.


High Salt Enhances Reactive Oxygen Species and Angiotensin II Contractions of Glomerular Afferent Arterioles From Mice With Reduced Renal Mass.

Li L, Lai EY, Luo Z, Solis G, Mendonca M, Griendling KK, Wellstein A, Welch WJ, Wilcox CS.

Hypertension. 2018 Nov;72(5):1208-1216. doi: 10.1161/HYPERTENSIONAHA.118.11354.


Enhanced Renal Afferent Arteriolar Reactive Oxygen Species and Contractility to Endothelin-1 Are Associated with Canonical Wnt Signaling in Diabetic Mice.

Zhang S, Huang Q, Wang Q, Wang Q, Cao X, Zhao L, Xu N, Zhuge Z, Mao J, Fu X, Liu R, Wilcox CS, Patzak A, Li L, Lai EY.

Kidney Blood Press Res. 2018;43(3):860-871. doi: 10.1159/000490334. Epub 2018 May 30.


Regulation of fluid reabsorption in rat or mouse proximal renal tubules by asymmetric dimethylarginine and dimethylarginine dimethylaminohydrolase 1.

Bell T, Araujo M, Luo Z, Tomlinson J, Leiper J, Welch WJ, Wilcox CS.

Am J Physiol Renal Physiol. 2018 Jul 1;315(1):F74-F78. doi: 10.1152/ajprenal.00560.2017. Epub 2018 Mar 7.


Interaction Between the Sodium-Glucose-Linked Transporter 2 Inhibitor Dapagliflozin and the Loop Diuretic Bumetanide in Normal Human Subjects.

Wilcox CS, Shen W, Boulton DW, Leslie BR, Griffen SC.

J Am Heart Assoc. 2018 Feb 10;7(4). pii: e007046. doi: 10.1161/JAHA.117.007046.


NRF2 prevents hypertension, increased ADMA, microvascular oxidative stress, and dysfunction in mice with two weeks of ANG II infusion.

Wang C, Luo Z, Carter G, Wellstein A, Jose PA, Tomlinson J, Leiper J, Welch WJ, Wilcox CS, Wang D.

Am J Physiol Regul Integr Comp Physiol. 2018 Mar 1;314(3):R399-R406. doi: 10.1152/ajpregu.00122.2017. Epub 2017 Nov 22.


Blood Pressure Control by a Secreted FGFBP1 (Fibroblast Growth Factor-Binding Protein).

Tassi E, Lai EY, Li L, Solis G, Chen Y, Kietzman WE, Ray PE, Riegel AT, Welch WJ, Wilcox CS, Wellstein A.

Hypertension. 2018 Jan;71(1):160-167. doi: 10.1161/HYPERTENSIONAHA.117.10268. Epub 2017 Nov 20.


Asymmetric solution-phase mixture aldol reaction using oligomeric ethylene glycol tagged chiral oxazolidinones.

Turkyilmaz S, Wilcox CS.

Tetrahedron Lett. 2017 May 24;58(21):2031-2033. doi: 10.1016/j.tetlet.2017.04.026. Epub 2017 Apr 6.


Sodium and Fluid Excretion With Torsemide in Healthy Subjects is Limited by the Short Duration of Diuretic Action.

Shah S, Pitt B, Brater DC, Feig PU, Shen W, Khwaja FS, Wilcox CS.

J Am Heart Assoc. 2017 Oct 5;6(10). pii: e006135. doi: 10.1161/JAHA.117.006135.


Melatonin ameliorates hypoglycemic stress-induced brain endothelial tight junction injury by inhibiting protein nitration of TP53-induced glycolysis and apoptosis regulator.

Wang CK, Ahmed MM, Jiang Q, Lu NN, Tan C, Gao YP, Mahmood Q, Chen DY, Fukunaga K, Li M, Chen Z, Wilcox CS, Lu YM, Qin ZH, Han F.

J Pineal Res. 2017 Nov;63(4). doi: 10.1111/jpi.12440. Epub 2017 Sep 6.


Cardiovascular outcome trials in patients with chronic kidney disease: challenges associated with selection of patients and endpoints.

Rossignol P, Agarwal R, Canaud B, Charney A, Chatellier G, Craig JC, Cushman WC, Gansevoort RT, Fellström B, Garza D, Guzman N, Holtkamp FA, London GM, Massy ZA, Mebazaa A, Mol PGM, Pfeffer MA, Rosenberg Y, Ruilope LM, Seltzer J, Shah AM, Shah S, Singh B, Stefánsson BV, Stockbridge N, Stough WG, Thygesen K, Walsh M, Wanner C, Warnock DG, Wilcox CS, Wittes J, Pitt B, Thompson A, Zannad F.

Eur Heart J. 2019 Mar 14;40(11):880-886. doi: 10.1093/eurheartj/ehx209.


Superoxide and hydrogen peroxide counterregulate myogenic contractions in renal afferent arterioles from a mouse model of chronic kidney disease.

Li L, Lai EY, Luo Z, Solis G, Griendling KK, Taylor WR, Jose PA, Wellstein A, Welch WJ, Wilcox CS.

Kidney Int. 2017 Sep;92(3):625-633. doi: 10.1016/j.kint.2017.02.009. Epub 2017 Apr 7. Erratum in: Kidney Int. 2017 Dec;92(6):1558.


Nitration of TRPM2 as a Molecular Switch Induces Autophagy During Brain Pericyte Injury.

Jiang Q, Gao Y, Wang C, Tao R, Wu Y, Zhan K, Liao M, Lu N, Lu Y, Wilcox CS, Luo J, Jiang LH, Yang W, Han F.

Antioxid Redox Signal. 2017 Dec 1;27(16):1297-1316. doi: 10.1089/ars.2016.6873. Epub 2017 Apr 18.


Inhibition of ROMK blocks macula densa tubuloglomerular feedback yet causes renal vasoconstriction in anesthetized rats.

Araujo M, Welch WJ, Zhou X, Sullivan K, Walsh S, Pasternak A, Wilcox CS.

Am J Physiol Renal Physiol. 2017 Jun 1;312(6):F1120-F1127. doi: 10.1152/ajprenal.00662.2016. Epub 2017 Feb 22.


Acute Kidney Injury and In-Hospital Mortality after Coronary Artery Bypass Graft versus Percutaneous Coronary Intervention: A Nationwide Study.

Shen W, Aguilar R, Montero AR, Fernandez SJ, Taylor AJ, Wilcox CS, Lipkowitz MS, Umans JG.

Am J Nephrol. 2017;45(3):217-225. doi: 10.1159/000455906. Epub 2017 Jan 31.


Synthesis and NMR Analysis of a Conformationally Controlled β-Turn Mimetic Torsion Balance.

Lypson AB, Wilcox CS.

J Org Chem. 2017 Jan 20;82(2):898-909. doi: 10.1021/acs.joc.6b02307. Epub 2017 Jan 10.


Reno-Cerebral Reflex Activates the Renin-Angiotensin System, Promoting Oxidative Stress and Renal Damage After Ischemia-Reperfusion Injury.

Cao W, Li A, Li J, Wu C, Cui S, Zhou Z, Liu Y, Wilcox CS, Hou FF.

Antioxid Redox Signal. 2017 Sep 1;27(7):415-432. doi: 10.1089/ars.2016.6827. Epub 2017 Jan 31.


Patiromer Decreases Serum Potassium and Phosphate Levels in Patients on Hemodialysis.

Bushinsky DA, Rossignol P, Spiegel DM, Benton WW, Yuan J, Block GA, Wilcox CS, Agarwal R.

Am J Nephrol. 2016;44(5):404-410. Epub 2016 Oct 27.


High-salt diet induces outward remodelling of efferent arterioles in mice with reduced renal mass.

Zhao L, Gao Y, Cao X, Gao D, Zhou S, Zhang S, Cai X, Han F, Wilcox CS, Li L, Lai EY.

Acta Physiol (Oxf). 2017 Mar;219(3):652-659. doi: 10.1111/apha.12759. Epub 2016 Aug 15.


Increased hydrogen peroxide impairs angiotensin II contractions of afferent arterioles in mice after renal ischaemia-reperfusion injury.

Huang Q, Wang Q, Zhang S, Jiang S, Zhao L, Yu L, Hultström M, Patzak A, Li L, Wilcox CS, Lai EY.

Acta Physiol (Oxf). 2016 Oct;218(2):136-45. doi: 10.1111/apha.12745. Epub 2016 Jul 15.


Differential effects of superoxide and hydrogen peroxide on myogenic signaling, membrane potential, and contractions of mouse renal afferent arterioles.

Li L, Lai EY, Wellstein A, Welch WJ, Wilcox CS.

Am J Physiol Renal Physiol. 2016 Jun 1;310(11):F1197-205. doi: 10.1152/ajprenal.00575.2015. Epub 2016 Apr 6.


Protective Effect of Tempol on Acute Kidney Injury Through PI3K/Akt/Nrf2 Signaling Pathway.

Zhang G, Wang Q, Zhou Q, Wang R, Xu M, Wang H, Wang L, Wilcox CS, Liu R, Lai EY.

Kidney Blood Press Res. 2016;41(2):129-38. doi: 10.1159/000443414. Epub 2016 Feb 22.


A local renal renin-angiotensin system activation via renal uptake of prorenin and angiotensinogen in diabetic rats.

Tojo A, Kinugasa S, Fujita T, Wilcox CS.

Diabetes Metab Syndr Obes. 2016 Jan 18;9:1-10. doi: 10.2147/DMSO.S91245. eCollection 2016.


Sympathoexcitation in Rats With Chronic Heart Failure Depends on Homeobox D10 and MicroRNA-7b Inhibiting GABBR1 Translation in Paraventricular Nucleus.

Wang R, Huang Q, Zhou R, Dong Z, Qi Y, Li H, Wei X, Wu H, Wang H, Wilcox CS, Hultström M, Zhou X, Lai EY.

Circ Heart Fail. 2016 Jan;9(1):e002261. doi: 10.1161/CIRCHEARTFAILURE.115.002261. Epub 2015 Dec 23.


Remodeling of Afferent Arterioles From Mice With Oxidative Stress Does Not Account for Increased Contractility but Does Limit Excessive Wall Stress.

Li L, Feng D, Luo Z, Welch WJ, Wilcox CS, Lai EY.

Hypertension. 2015 Sep;66(3):550-6. doi: 10.1161/HYPERTENSIONAHA.115.05631. Epub 2015 Jun 22.


P2RX7 sensitizes Mac-1/ICAM-1-dependent leukocyte-endothelial adhesion and promotes neurovascular injury during septic encephalopathy.

Wang H, Hong LJ, Huang JY, Jiang Q, Tao RR, Tan C, Lu NN, Wang CK, Ahmed MM, Lu YM, Liu ZR, Shi WX, Lai EY, Wilcox CS, Han F.

Cell Res. 2015 Jun;25(6):674-90. doi: 10.1038/cr.2015.61. Epub 2015 May 22.


Reduced Renal Methylarginine Metabolism Protects against Progressive Kidney Damage.

Tomlinson JA, Caplin B, Boruc O, Bruce-Cobbold C, Cutillas P, Dormann D, Faull P, Grossman RC, Khadayate S, Mas VR, Nitsch DD, Wang Z, Norman JT, Wilcox CS, Wheeler DC, Leiper J.

J Am Soc Nephrol. 2015 Dec;26(12):3045-59. doi: 10.1681/ASN.2014030280. Epub 2015 Apr 8.


Renal autoregulation in health and disease.

Carlström M, Wilcox CS, Arendshorst WJ.

Physiol Rev. 2015 Apr;95(2):405-511. doi: 10.1152/physrev.00042.2012. Review.


Thromboxane prostanoid receptors enhance contractions, endothelin-1, and oxidative stress in microvessels from mice with chronic kidney disease.

Wang C, Luo Z, Kohan D, Wellstein A, Jose PA, Welch WJ, Wilcox CS, Wang D.

Hypertension. 2015 May;65(5):1055-63. doi: 10.1161/HYPERTENSIONAHA.115.05244. Epub 2015 Mar 2.


A Salt-Induced Reno-Cerebral Reflex Activates Renin-Angiotensin Systems and Promotes CKD Progression.

Cao W, Li A, Wang L, Zhou Z, Su Z, Bin W, Wilcox CS, Hou FF.

J Am Soc Nephrol. 2015 Jul;26(7):1619-33. doi: 10.1681/ASN.2014050518. Epub 2015 Jan 29.


Midkine Regulates BP through Cytochrome P450-Derived Eicosanoids.

Sato Y, Sato W, Maruyama S, Wilcox CS, Falck JR, Masuda T, Kosugi T, Kojima H, Maeda K, Furuhashi K, Ando M, Imai E, Matsuo S, Kadomatsu K.

J Am Soc Nephrol. 2015 Aug;26(8):1806-15. doi: 10.1681/ASN.2013121259. Epub 2014 Nov 5.


Microvascular Endothelial Dysfunction and Enhanced Thromboxane and Endothelial Contractility in Patients with HIV.

Wang D, Melancon JK, Verbesey J, Hu H, Liu C, Aslam S, Young M, Wilcox CS.

J AIDS Clin Res. 2013 Dec 1;4(12):267.


What level of sodium intake worsens renal outcomes?

Lipkowitz MS, Wilcox CS.

Am J Hypertens. 2014 Oct;27(10):1243-4. doi: 10.1093/ajh/hpu067. Epub 2014 May 10. No abstract available.


In vivo two-photon fluorescence microscopy reveals disturbed cerebral capillary blood flow and increased susceptibility to ischemic insults in diabetic mice.

Huang JY, Li LT, Wang H, Liu SS, Lu YM, Liao MH, Tao RR, Hong LJ, Fukunaga K, Chen Z, Wilcox CS, Lai EY, Han F.

CNS Neurosci Ther. 2014 Sep;20(9):816-22. doi: 10.1111/cns.12268. Epub 2014 Apr 8.


Endothelial dysfunction and enhanced contractility in microvessels from ovariectomized rats: roles of oxidative stress and perivascular adipose tissue.

Wang D, Wang C, Wu X, Zheng W, Sandberg K, Ji H, Welch WJ, Wilcox CS.

Hypertension. 2014 May;63(5):1063-9. doi: 10.1161/HYPERTENSIONAHA.113.02284. Epub 2014 Mar 3.


Nitrosative stress induces peroxiredoxin 1 ubiquitination during ischemic insult via E6AP activation in endothelial cells both in vitro and in vivo.

Tao RR, Wang H, Hong LJ, Huang JY, Lu YM, Liao MH, Ye WF, Lu NN, Zhu DY, Huang Q, Fukunaga K, Lou YJ, Shoji I, Wilcox CS, Lai EY, Han F.

Antioxid Redox Signal. 2014 Jul 1;21(1):1-16. doi: 10.1089/ars.2013.5381. Epub 2014 Feb 4.


Repeated mixing and isolation: measuring chronic, intermittent stress in Holstein calves.

Wilcox CS, Schutz MM, Rostagno MR, Lay DC Jr, Eicher SD.

J Dairy Sci. 2013;96(11):7223-33. doi: 10.3168/jds.2013-6944. Epub 2013 Sep 18.


CNS sites cooperate to detect duplicate subjects with a clinical trial subject registry.

Shiovitz TM, Wilcox CS, Gevorgyan L, Shawkat A.

Innov Clin Neurosci. 2013 Feb;10(2):17-21.


Rotational isomers of N-methyl-N-arylacetamides and their derived enolates: implications for asymmetric Hartwig oxindole cyclizations.

Mandel J, Pan X, Hay EB, Geib SJ, Wilcox CS, Curran DP.

J Org Chem. 2013 Apr 19;78(8):4083-9. doi: 10.1021/jo400385t. Epub 2013 Apr 9.


Oxidative stress in hypertension: role of the kidney.

Araujo M, Wilcox CS.

Antioxid Redox Signal. 2014 Jan 1;20(1):74-101. doi: 10.1089/ars.2013.5259. Epub 2013 Apr 30. Review.


On the obituary for George E. Schreiner.

Wilcox CS.

Kidney Int. 2012 Nov;82(10):1136. doi: 10.1038/ki.2012.353. No abstract available.


Feeding behaviors of transition dairy cows fed glycerol as a replacement for corn.

Carvalho ER, Schmelz-Roberts NS, White HM, Wilcox CS, Eicher SD, Donkin SS.

J Dairy Sci. 2012 Dec;95(12):7214-24. doi: 10.3168/jds.2010-3584. Epub 2012 Oct 22.


Renal afferent arteriolar and tubuloglomerular feedback reactivity in mice with conditional deletions of adenosine 1 receptors.

Li L, Lai EY, Huang Y, Eisner C, Mizel D, Wilcox CS, Schnermann J.

Am J Physiol Renal Physiol. 2012 Oct 15;303(8):F1166-75. doi: 10.1152/ajprenal.00222.2012. Epub 2012 Aug 15.


Minocycline-induced renal polyarteritis nodosa.

Tabriziani H, Wilcox CS, Gilbert ON, Lipkowitz MS.

BMJ Case Rep. 2012 Aug 13;2012. pii: bcr2012006503. doi: 10.1136/bcr-2012-006503.

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