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Items: 1 to 50 of 289

1.

Identification and Preliminary Validation of a Plasma Profile Associated with Cognitive Decline in Dementia and At-Risk Individuals: A Retrospective Cohort Analysis.

Iulita MF, Ganesh A, Pentz R, Flores Aguilar L, Gubert P, Ducatenzeiler A, Christie S, Wilcock GK, Cuello AC.

J Alzheimers Dis. 2019;67(1):327-341. doi: 10.3233/JAD-180970.

PMID:
30636741
2.

Potential of Low Dose Leuco-Methylthioninium Bis(Hydromethanesulphonate) (LMTM) Monotherapy for Treatment of Mild Alzheimer's Disease: Cohort Analysis as Modified Primary Outcome in a Phase III Clinical Trial.

Wilcock GK, Gauthier S, Frisoni GB, Jia J, Hardlund JH, Moebius HJ, Bentham P, Kook KA, Schelter BO, Wischik DJ, Davis CS, Staff RT, Vuksanovic V, Ahearn T, Bracoud L, Shamsi K, Marek K, Seibyl J, Riedel G, Storey JMD, Harrington CR, Wischik CM.

J Alzheimers Dis. 2018;61(1):435-457. doi: 10.3233/JAD-170560.

3.

Sleep-Wake Patterns and Cognition of Older Adults with Amnestic Mild Cognitive Impairment (aMCI): A Comparison with Cognitively Healthy Adults and Moderate Alzheimer's Disease Patients.

Wams EJ, Wilcock GK, Foster RG, Wulff K.

Curr Alzheimer Res. 2017;14(10):1030-1041. doi: 10.2174/1567205014666170523095634.

PMID:
28545363
4.

Donepezil Enhances Frontal Functional Connectivity in Alzheimer's Disease: A Pilot Study.

Griffanti L, Wilcock GK, Voets N, Bonifacio G, Mackay CE, Jenkinson M, Zamboni G.

Dement Geriatr Cogn Dis Extra. 2016 Oct 21;6(3):518-528. eCollection 2016 Sep-Dec.

5.

Efficacy and safety of tau-aggregation inhibitor therapy in patients with mild or moderate Alzheimer's disease: a randomised, controlled, double-blind, parallel-arm, phase 3 trial.

Gauthier S, Feldman HH, Schneider LS, Wilcock GK, Frisoni GB, Hardlund JH, Moebius HJ, Bentham P, Kook KA, Wischik DJ, Schelter BO, Davis CS, Staff RT, Bracoud L, Shamsi K, Storey JM, Harrington CR, Wischik CM.

Lancet. 2016 Dec 10;388(10062):2873-2884. doi: 10.1016/S0140-6736(16)31275-2. Epub 2016 Nov 16.

6.

A Validation Study of Vascular Cognitive Impairment Genetics Meta-Analysis Findings in an Independent Collaborative Cohort.

Skrobot OA, McKnight AJ, Passmore PA, Seripa D, Mecocci P, Panza F, Kalaria R, Wilcock G, Munafò M, Erkinjuntti T, Karhunen P, Pessi T, Martiskainen M, Love S; Genetic and Environmental Risk for Alzheimer’s disease Consortium (GERAD1), Kehoe PG.

J Alzheimers Dis. 2016 Jun 15;53(3):981-9. doi: 10.3233/JAD-150862.

PMID:
27314523
7.

Registries and Cohorts to Accelerate Early Phase Alzheimer's Trials. A Report from the E.U./U.S. Clinical Trials in Alzheimer's Disease Task Force.

Aisen P, Touchon J, Andrieu S, Boada M, Doody R, Nosheny RL, Langbaum JB, Schneider L, Hendrix S, Wilcock G, Molinuevo JL, Ritchie C, Ousset PJ, Cummings J, Sperling R, DeKosky ST, Lovestone S, Hampel H, Petersen R, Legrand V, Egan M, Randolph C, Salloway S, Weiner M, Vellas B.

J Prev Alzheimers Dis. 2016;3(2):68-74. doi: 10.14283/jpad.2016.97.

PMID:
29210442
8.

Subjective Cognitive Decline.

Tales A, Jessen F, Butler C, Wilcock G, Phillips J, Bayer T.

J Alzheimers Dis. 2015 Sep 24;48 Suppl 1:S1-3. doi: 10.3233/JAD-150719. No abstract available.

9.

Brain health: the importance of recognizing cognitive impairment: an IAGG consensus conference.

Morley JE, Morris JC, Berg-Weger M, Borson S, Carpenter BD, Del Campo N, Dubois B, Fargo K, Fitten LJ, Flaherty JH, Ganguli M, Grossberg GT, Malmstrom TK, Petersen RD, Rodriguez C, Saykin AJ, Scheltens P, Tangalos EG, Verghese J, Wilcock G, Winblad B, Woo J, Vellas B.

J Am Med Dir Assoc. 2015 Sep 1;16(9):731-9. doi: 10.1016/j.jamda.2015.06.017.

10.

Investigating virtual reality navigation in amnestic mild cognitive impairment using fMRI.

Migo EM, O'Daly O, Mitterschiffthaler M, Antonova E, Dawson GR, Dourish CT, Craig KJ, Simmons A, Wilcock GK, McCulloch E, Jackson SH, Kopelman MD, Williams SC, Morris RG.

Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2016;23(2):196-217. doi: 10.1080/13825585.2015.1073218. Epub 2015 Aug 3.

PMID:
26234803
11.

Aberrant functional connectivity within the basal ganglia of patients with Parkinson's disease.

Rolinski M, Griffanti L, Szewczyk-Krolikowski K, Menke RA, Wilcock GK, Filippini N, Zamboni G, Hu MT, Mackay CE.

Neuroimage Clin. 2015 Apr 9;8:126-32. doi: 10.1016/j.nicl.2015.04.003. eCollection 2015.

12.

Cerebral amyloid angiopathy, subcortical white matter disease and dementia: literature review and study in OPTIMA.

Esiri M, Chance S, Joachim C, Warden D, Smallwood A, Sloan C, Christie S, Wilcock G, Smith AD.

Brain Pathol. 2015 Jan;25(1):51-62. doi: 10.1111/bpa.12221. Review.

PMID:
25521177
13.

Cerebrospinal fluid biomarkers distinguish postmortem-confirmed Alzheimer's disease from other dementias and healthy controls in the OPTIMA cohort.

Seeburger JL, Holder DJ, Combrinck M, Joachim C, Laterza O, Tanen M, Dallob A, Chappell D, Snyder K, Flynn M, Simon A, Modur V, Potter WZ, Wilcock G, Savage MJ, Smith AD.

J Alzheimers Dis. 2015;44(2):525-39. doi: 10.3233/JAD-141725.

PMID:
25391385
14.

A type 2 biomarker separates relapsing-remitting from secondary progressive multiple sclerosis.

Dickens AM, Larkin JR, Griffin JL, Cavey A, Matthews L, Turner MR, Wilcock GK, Davis BG, Claridge TD, Palace J, Anthony DC, Sibson NR.

Neurology. 2014 Oct 21;83(17):1492-9. doi: 10.1212/WNL.0000000000000905. Epub 2014 Sep 24.

15.

The use of biomarkers for the etiologic diagnosis of MCI in Europe: an EADC survey.

Bocchetta M, Galluzzi S, Kehoe PG, Aguera E, Bernabei R, Bullock R, Ceccaldi M, Dartigues JF, de Mendonça A, Didic M, Eriksdotter M, Félician O, Frölich L, Gertz HJ, Hallikainen M, Hasselbalch SG, Hausner L, Heuser I, Jessen F, Jones RW, Kurz A, Lawlor B, Lleo A, Martinez-Lage P, Mecocci P, Mehrabian S, Monsch A, Nobili F, Nordberg A, Rikkert MO, Orgogozo JM, Pasquier F, Peters O, Salmon E, Sánchez-Castellano C, Santana I, Sarazin M, Traykov L, Tsolaki M, Visser PJ, Wallin ÅK, Wilcock G, Wilkinson D, Wolf H, Yener G, Zekry D, Frisoni GB.

Alzheimers Dement. 2015 Feb;11(2):195-206.e1. doi: 10.1016/j.jalz.2014.06.006. Epub 2014 Aug 20.

PMID:
25150733
16.

Is there more to subjective cognitive impairment than meets the eye? Raising awareness.

Tales A, Wilcock GK, Phillips JE, Bayer A.

J Alzheimers Dis. 2014;41(3):665-6. doi: 10.3233/JAD-141294. No abstract available.

PMID:
25024320
17.

Practical detection of a definitive biomarker panel for Alzheimer's disease; comparisons between matched plasma and cerebrospinal fluid.

Richens JL, Vere KA, Light RA, Soria D, Garibaldi J, Smith AD, Warden D, Wilcock G, Bajaj N, Morgan K, O'Shea P.

Int J Mol Epidemiol Genet. 2014 May 29;5(2):53-70. eCollection 2014.

18.

Reporting standards for studies of diagnostic test accuracy in dementia: The STARDdem Initiative.

Noel-Storr AH, McCleery JM, Richard E, Ritchie CW, Flicker L, Cullum SJ, Davis D, Quinn TJ, Hyde C, Rutjes AW, Smailagic N, Marcus S, Black S, Blennow K, Brayne C, Fiorivanti M, Johnson JK, Köpke S, Schneider LS, Simmons A, Mattsson N, Zetterberg H, Bossuyt PM, Wilcock G, McShane R.

Neurology. 2014 Jul 22;83(4):364-73. doi: 10.1212/WNL.0000000000000621. Epub 2014 Jun 18.

19.

Is there more to subjective cognitive impairment than meets the eye? A perspective.

Tales A, Wilcock GK, Phillips JE, Bayer A.

J Alzheimers Dis. 2014;41(3):655-61. doi: 10.3233/JAD-132414. Review.

PMID:
24898657
20.

Alterations in working memory networks in amnestic mild cognitive impairment.

Migo EM, Mitterschiffthaler M, O'Daly O, Dawson GR, Dourish CT, Craig KJ, Simmons A, Wilcock GK, McCulloch E, Jackson SH, Kopelman MD, Williams SC, Morris RG.

Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2015;22(1):106-27. doi: 10.1080/13825585.2014.894958. Epub 2014 Mar 12.

PMID:
24617815
21.

The development and validation of a patient-reported quality of life measure for people with mild cognitive impairment.

Dean K, Jenkinson C, Wilcock G, Walker Z.

Int Psychogeriatr. 2014 Mar;26(3):487-97. doi: 10.1017/S1041610213002251. Epub 2013 Dec 5.

PMID:
24308688
22.

Exploring the experiences of people with mild cognitive impairment and their caregivers with particular reference to healthcare - a qualitative study.

Dean K, Jenkinson C, Wilcock G, Walker Z.

Int Psychogeriatr. 2014 Mar;26(3):475-85. doi: 10.1017/S104161021300207X. Epub 2013 Nov 28.

PMID:
24284179
23.

Dysfunction of the mTOR pathway is a risk factor for Alzheimer's disease.

Yates SC, Zafar A, Hubbard P, Nagy S, Durant S, Bicknell R, Wilcock G, Christie S, Esiri MM, Smith AD, Nagy Z.

Acta Neuropathol Commun. 2013 May 8;1:3. doi: 10.1186/2051-5960-1-3.

24.

Population-based case-control study of white matter changes on brain imaging in transient ischemic attack and ischemic stroke.

Li L, Simoni M, Küker W, Schulz UG, Christie S, Wilcock GK, Rothwell PM.

Stroke. 2013 Nov;44(11):3063-70. doi: 10.1161/STROKEAHA.113.002775. Epub 2013 Sep 10.

PMID:
24021688
25.

Computerized adaptation of The Placing Test for early detection of both mild cognitive impairment and Alzheimer's disease.

Vacante M, Wilcock GK, de Jager CA.

J Clin Exp Neuropsychol. 2013;35(8):846-56. doi: 10.1080/13803395.2013.825235. Epub 2013 Aug 28.

PMID:
23985007
26.

Cerebral subcortical small vessel disease in subjects with pathologically confirmed Alzheimer disease: a clinicopathologic study in the Oxford Project to Investigate Memory and Ageing (OPTIMA).

Esiri MM, Joachim C, Sloan C, Christie S, Agacinski G, Bridges LR, Wilcock GK, Smith AD.

Alzheimer Dis Assoc Disord. 2014 Jan-Mar;28(1):30-5. doi: 10.1097/WAD.0b013e31829b72f1.

PMID:
23842286
27.

Designing drug trials for Alzheimer's disease: what we have learned from the release of the phase III antibody trials: a report from the EU/US/CTAD Task Force.

Vellas B, Carrillo MC, Sampaio C, Brashear HR, Siemers E, Hampel H, Schneider LS, Weiner M, Doody R, Khachaturian Z, Cedarbaum J, Grundman M, Broich K, Giacobini E, Dubois B, Sperling R, Wilcock GK, Fox N, Scheltens P, Touchon J, Hendrix S, Andrieu S, Aisen P; EU/US/CTAD Task Force Members.

Alzheimers Dement. 2013 Jul;9(4):438-44. doi: 10.1016/j.jalz.2013.03.007.

PMID:
23809364
28.

The sex-specific associations of the aromatase gene with Alzheimer's disease and its interaction with IL10 in the Epistasis Project.

Medway C, Combarros O, Cortina-Borja M, Butler HT, Ibrahim-Verbaas CA, de Bruijn RF, Koudstaal PJ, van Duijn CM, Ikram MA, Mateo I, Sánchez-Juan P, Lehmann MG, Heun R, Kölsch H, Deloukas P, Hammond N, Coto E, Alvarez V, Kehoe PG, Barber R, Wilcock GK, Brown K, Belbin O, Warden DR, Smith AD, Morgan K, Lehmann DJ.

Eur J Hum Genet. 2014 Feb;22(2):216-20. doi: 10.1038/ejhg.2013.116. Epub 2013 Jun 5.

29.

Resting functional connectivity reveals residual functional activity in Alzheimer's disease.

Zamboni G, Wilcock GK, Douaud G, Drazich E, McCulloch E, Filippini N, Tracey I, Brooks JC, Smith SM, Jenkinson M, Mackay CE.

Biol Psychiatry. 2013 Sep 1;74(5):375-83. doi: 10.1016/j.biopsych.2013.04.015. Epub 2013 May 28.

PMID:
23726515
30.

Single-domain amnestic mild cognitive impairment identified by cluster analysis predicts Alzheimer's disease in the european prospective DESCRIPA study.

Damian M, Hausner L, Jekel K, Richter M, Froelich L, Almkvist O, Boada M, Bullock R, De Deyn PP, Frisoni GB, Hampel H, Jones RW, Kehoe P, Lenoir H, Minthon L, Olde Rikkert MG, Rodriguez G, Scheltens P, Soininen H, Spiru L, Touchon J, Tsolaki M, Vellas B, Verhey FR, Winblad B, Wahlund LO, Wilcock G, Visser PJ.

Dement Geriatr Cogn Disord. 2013;36(1-2):1-19. doi: 10.1159/000348354. Epub 2013 May 3.

PMID:
23651945
31.

Role of depression in predicting time to conversion to mild cognitive impairment.

Dean K, Oulhaj A, Zamboni G, deJager CA, Wilcock GK.

Am J Geriatr Psychiatry. 2014 Jul;22(7):727-34. doi: 10.1016/j.jagp.2012.12.025. Epub 2013 Apr 20.

PMID:
23611364
32.

Use of whole blood for analysis of disease-associated biomarkers.

May JE, Pemberton RM, Hart JP, McLeod J, Wilcock G, Doran O.

Anal Biochem. 2013 Jun 1;437(1):59-61. doi: 10.1016/j.ab.2013.02.024. Epub 2013 Mar 4.

PMID:
23467100
33.

The association between APOE ε4 and Alzheimer-type dementia among memory clinic patients is confined to those with a higher education. The DESCRIPA Study.

Vermeiren AP, Bosma H, Visser PJ, Zeegers MP, Graff C, Ewers M, Frisoni GB, Frölich L, Hampel H, Jones RW, Kehoe PG, Lenoir H, Minthon L, Nobili FM, Olde Rikkert M, Rigaud AS, Scheltens P, Soininen H, Spiru L, Tsolaki M, Wahlund LO, Vellas B, Wilcock G, Elias-Sonnenschein LS, Verhey FR.

J Alzheimers Dis. 2013;35(2):241-6. doi: 10.3233/JAD-122182.

PMID:
23380990
34.

An assessment of neurocognitive speed in relation to frailty.

Rolfson DB, Wilcock G, Mitnitski A, King E, de Jager CA, Rockwood K, Fallah N, Searle SD.

Age Ageing. 2013 Mar;42(2):191-6. doi: 10.1093/ageing/afs185. Epub 2013 Jan 7.

PMID:
23296141
35.

Discovery by the Epistasis Project of an epistatic interaction between the GSTM3 gene and the HHEX/IDE/KIF11 locus in the risk of Alzheimer's disease.

Bullock JM, Medway C, Cortina-Borja M, Turton JC, Prince JA, Ibrahim-Verbaas CA, Schuur M, Breteler MM, van Duijn CM, Kehoe PG, Barber R, Coto E, Alvarez V, Deloukas P, Hammond N, Combarros O, Mateo I, Warden DR, Lehmann MG, Belbin O, Brown K, Wilcock GK, Heun R, Kölsch H, Smith AD, Lehmann DJ, Morgan K.

Neurobiol Aging. 2013 Apr;34(4):1309.e1-7. doi: 10.1016/j.neurobiolaging.2012.08.010. Epub 2012 Oct 1.

PMID:
23036584
36.

Structural and functional bases of visuospatial associative memory in older adults.

Zamboni G, de Jager CA, Drazich E, Douaud G, Jenkinson M, Smith AD, Tracey I, Wilcock GK.

Neurobiol Aging. 2013 Mar;34(3):961-72. doi: 10.1016/j.neurobiolaging.2012.07.011. Epub 2012 Aug 9.

PMID:
22883909
37.

Intra-individual reaction time variability in amnestic mild cognitive impairment: a precursor to dementia?

Tales A, Leonards U, Bompas A, Snowden RJ, Philips M, Porter G, Haworth J, Wilcock G, Bayer A.

J Alzheimers Dis. 2012;32(2):457-66. doi: 10.3233/JAD-2012-120505.

PMID:
22785393
38.

Differences in cognitive profile between TIA, stroke and elderly memory research subjects: a comparison of the MMSE and MoCA.

Pendlebury ST, Markwick A, de Jager CA, Zamboni G, Wilcock GK, Rothwell PM.

Cerebrovasc Dis. 2012;34(1):48-54. doi: 10.1159/000338905. Epub 2012 Jun 29.

PMID:
22759627
39.

Neuroanatomy of impaired self-awareness in Alzheimer's disease and mild cognitive impairment.

Zamboni G, Drazich E, McCulloch E, Filippini N, Mackay CE, Jenkinson M, Tracey I, Wilcock GK.

Cortex. 2013 Mar;49(3):668-78. doi: 10.1016/j.cortex.2012.04.011. Epub 2012 May 8.

PMID:
22677047
40.

Is MRI better than CT for detecting a vascular component to dementia? A systematic review and meta-analysis.

Beynon R, Sterne JA, Wilcock G, Likeman M, Harbord RM, Astin M, Burke M, Bessell A, Ben-Shlomo Y, Hawkins J, Hollingworth W, Whiting P.

BMC Neurol. 2012 Jun 6;12:33. doi: 10.1186/1471-2377-12-33. Review.

41.

Recent Alzheimer's disease research highlights.

Galasko D, Golde T, Wilcock G.

Alzheimers Res Ther. 2012 May 18;4(3):14. doi: 10.1186/alzrt117. No abstract available.

42.

Interactions between PPAR-α and inflammation-related cytokine genes on the development of Alzheimer's disease, observed by the Epistasis Project.

Heun R, Kölsch H, Ibrahim-Verbaas CA, Combarros O, Aulchenko YS, Breteler M, Schuur M, van Duijn CM, Hammond N, Belbin O, Cortina-Borja M, Wilcock GK, Brown K, Barber R, Kehoe PG, Coto E, Alvarez V, Lehmann MG, Deloukas P, Mateo I, Morgan K, Warden DR, Smith AD, Lehmann DJ.

Int J Mol Epidemiol Genet. 2012;3(1):39-47. Epub 2012 Feb 23.

43.

Living with mild cognitive impairment: the patient's and carer's experience.

Dean K, Wilcock G.

Int Psychogeriatr. 2012 Jun;24(6):871-81. doi: 10.1017/S104161021100264X. Epub 2012 Jan 17. Review.

PMID:
22251799
44.

Do instrumental activities of daily living predict dementia at 1- and 2-year follow-up? Findings from the Development of Screening guidelines and diagnostic Criteria for Predementia Alzheimer's disease study.

Sikkes SA, Visser PJ, Knol DL, de Lange-de Klerk ES, Tsolaki M, Frisoni GB, Nobili F, Spiru L, Rigaud AS, Frölich L, Rikkert MO, Soininen H, Touchon J, Wilcock G, Boada M, Hampel H, Bullock R, Vellas B, Pijnenburg YA, Scheltens P, Verhey FR, Uitdehaag BM.

J Am Geriatr Soc. 2011 Dec;59(12):2273-81. doi: 10.1111/j.1532-5415.2011.03732.x.

PMID:
22188074
45.

Preservation of cortical histamine H3 receptors in ischemic vascular and mixed dementias.

Sheng Y, Lee JH, Medhurst AD, Wilcock GK, Esiri M, Wong PT, Chen CP, Lai MK.

J Neurol Sci. 2012 Apr 15;315(1-2):110-4. doi: 10.1016/j.jns.2011.11.013. Epub 2011 Nov 29.

PMID:
22129936
46.

Interaction of insulin and PPAR-α genes in Alzheimer's disease: the Epistasis Project.

Kölsch H, Lehmann DJ, Ibrahim-Verbaas CA, Combarros O, van Duijn CM, Hammond N, Belbin O, Cortina-Borja M, Lehmann MG, Aulchenko YS, Schuur M, Breteler M, Wilcock GK, Brown K, Kehoe PG, Barber R, Coto E, Alvarez V, Deloukas P, Mateo I, Maier W, Morgan K, Warden DR, Smith AD, Heun R.

J Neural Transm (Vienna). 2012 Apr;119(4):473-9. doi: 10.1007/s00702-011-0732-4. Epub 2011 Nov 8.

PMID:
22065208
47.

Identification of SPARC-like 1 protein as part of a biomarker panel for Alzheimer's disease in cerebrospinal fluid.

Vafadar-Isfahani B, Ball G, Coveney C, Lemetre C, Boocock D, Minthon L, Hansson O, Miles AK, Janciauskiene SM, Warden D, Smith AD, Wilcock G, Kalsheker N, Rees R, Matharoo-Ball B, Morgan K.

J Alzheimers Dis. 2012;28(3):625-36. doi: 10.3233/JAD-2011-111505.

PMID:
22045497
48.

A comparison of screening tools for the assessment of mild cognitive impairment: preliminary findings.

Ahmed S, de Jager C, Wilcock G.

Neurocase. 2012;18(4):336-51. doi: 10.1080/13554794.2011.608365. Epub 2011 Nov 2.

PMID:
22044211
49.

Regional differences in effects of APOE ε4 on cognitive impairment in non-demented subjects.

Norberg J, Graff C, Almkvist O, Ewers M, Frisoni GB, Frölich L, Hampel H, Jones RW, Kehoe PG, Lenoir H, Minthon L, Nobili F, Olde Rikkert M, Rigaud AS, Scheltens P, Soininen H, Spiru L, Tsolaki M, Wahlund LO, Vellas B, Wilcock G, Elias-Sonnenschein LS, Verhey FR, Visser PJ.

Dement Geriatr Cogn Disord. 2011;32(2):135-42. doi: 10.1159/000330492. Epub 2011 Sep 22.

PMID:
21952537
50.

The vitamin D receptor gene is associated with Alzheimer's disease.

Lehmann DJ, Refsum H, Warden DR, Medway C, Wilcock GK, Smith AD.

Neurosci Lett. 2011 Oct 24;504(2):79-82. doi: 10.1016/j.neulet.2011.08.057. Epub 2011 Sep 3.

PMID:
21911036

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