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Items: 49


Effect of a pneumococcal whole cell vaccine on influenza A-induced pneumococcal otitis media in infant mice.

Manning J, Dunne EM, Wang N, Pedersen JS, Ogier JM, Burt RA, Mulholland EK, Robins-Browne RM, Malley R, Wijburg OL, Satzke C.

Vaccine. 2019 Jun 6;37(26):3495-3504. doi: 10.1016/j.vaccine.2019.03.013. Epub 2019 May 15.


Mus musculus deficient for secretory antibodies show delayed growth with an altered urinary metabolome.

Simpfendorfer KR, Wang N, Tull DL, De Souza DP, Nahid A, Mu A, Hocking DM, Pedersen JS, Wijburg OLC, McConville MJ, Strugnell RA.

Mol Med. 2019 Apr 3;25(1):12. doi: 10.1186/s10020-019-0077-2.


Increased autoimmune diabetes in pIgR-deficient NOD mice is due to a "Hitchhiking" interval that refines the genetic effect of Idd5.4.

Simpfendorfer KR, Strugnell RA, Brodnicki TC, Wijburg OL.

PLoS One. 2015 Apr 2;10(4):e0121979. doi: 10.1371/journal.pone.0121979. eCollection 2015.


Analysis of Salmonella enterica serovar Typhimurium variable-number tandem-repeat data for public health investigation based on measured mutation rates and whole-genome sequence comparisons.

Dimovski K, Cao H, Wijburg OL, Strugnell RA, Mantena RK, Whipp M, Hogg G, Holt KE.

J Bacteriol. 2014 Aug 15;196(16):3036-44. doi: 10.1128/JB.01820-14. Epub 2014 Jun 23.


Congenic mice reveal genetic epistasis and overlapping disease loci for autoimmune diabetes and listeriosis.

Wang N, Elso CM, Mackin L, Mannering SI, Strugnell RA, Wijburg OL, Brodnicki TC.

Immunogenetics. 2014 Aug;66(7-8):501-6. doi: 10.1007/s00251-014-0782-5. Epub 2014 Jun 7.


Evaluation of intra- and extra-epithelial secretory IgA in chlamydial infections.

Armitage CW, O'Meara CP, Harvie MC, Timms P, Wijburg OL, Beagley KW.

Immunology. 2014 Dec;143(4):520-30. doi: 10.1111/imm.12317.


Antibodies mediate formation of neutrophil extracellular traps in the middle ear and facilitate secondary pneumococcal otitis media.

Short KR, von Köckritz-Blickwede M, Langereis JD, Chew KY, Job ER, Armitage CW, Hatcher B, Fujihashi K, Reading PC, Hermans PW, Wijburg OL, Diavatopoulos DA.

Infect Immun. 2014 Jan;82(1):364-70. doi: 10.1128/IAI.01104-13. Epub 2013 Nov 4.


Contribution of secretory antibodies to intestinal mucosal immunity against Helicobacter pylori.

Gorrell RJ, Wijburg OL, Pedersen JS, Walduck AK, Kwok T, Strugnell RA, Robins-Browne RM.

Infect Immun. 2013 Oct;81(10):3880-93. doi: 10.1128/IAI.01424-12. Epub 2013 Aug 5.


Systemic infection of Mice with Listeria monocytogenes to characterize host immune responses.

Wang N, Strugnell RA, Wijburg OL, Brodnicki TC.

Methods Mol Biol. 2013;1031:125-44. doi: 10.1007/978-1-62703-481-4_16.


Influenza A virus induced bacterial otitis media is independent of virus tropism for α2,6-linked sialic acid.

Short KR, Habets MN, Payne J, Reading PC, Diavatopoulos DA, Wijburg OL.

Virol J. 2013 Apr 23;10:128. doi: 10.1186/1743-422X-10-128.


Increased antigen specific T cell numbers in the absence of altered migration or division rates as a result of mucosal cholera toxin administration.

Kaparakis-Liaskos M, Tate MD, Price JD, Pearse M, Wijburg OL.

PLoS One. 2013;8(3):e59934. doi: 10.1371/journal.pone.0059934. Epub 2013 Mar 27.


Influenza-induced inflammation drives pneumococcal otitis media.

Short KR, Reading PC, Brown LE, Pedersen J, Gilbertson B, Job ER, Edenborough KM, Habets MN, Zomer A, Hermans PW, Diavatopoulos DA, Wijburg OL.

Infect Immun. 2013 Mar;81(3):645-52. doi: 10.1128/IAI.01278-12. Epub 2013 Jan 14.


Increased nasopharyngeal bacterial titers and local inflammation facilitate transmission of Streptococcus pneumoniae.

Short KR, Reading PC, Wang N, Diavatopoulos DA, Wijburg OL.

MBio. 2012 Sep 25;3(5). pii: e00255-12. doi: 10.1128/mBio.00255-12. Print 2012.


NLRC4 inflammasomes in dendritic cells regulate noncognate effector function by memory CD8⁺ T cells.

Kupz A, Guarda G, Gebhardt T, Sander LE, Short KR, Diavatopoulos DA, Wijburg OL, Cao H, Waithman JC, Chen W, Fernandez-Ruiz D, Whitney PG, Heath WR, Curtiss R 3rd, Tschopp J, Strugnell RA, Bedoui S.

Nat Immunol. 2012 Jan 8;13(2):162-9. doi: 10.1038/ni.2195.


Influenza virus induces bacterial and nonbacterial otitis media.

Short KR, Diavatopoulos DA, Thornton R, Pedersen J, Strugnell RA, Wise AK, Reading PC, Wijburg OL.

J Infect Dis. 2011 Dec 15;204(12):1857-65. doi: 10.1093/infdis/jir618. Epub 2011 Sep 19.


MrkH, a novel c-di-GMP-dependent transcriptional activator, controls Klebsiella pneumoniae biofilm formation by regulating type 3 fimbriae expression.

Wilksch JJ, Yang J, Clements A, Gabbe JL, Short KR, Cao H, Cavaliere R, James CE, Whitchurch CB, Schembri MA, Chuah ML, Liang ZX, Wijburg OL, Jenney AW, Lithgow T, Strugnell RA.

PLoS Pathog. 2011 Aug;7(8):e1002204. doi: 10.1371/journal.ppat.1002204. Epub 2011 Aug 25.


Using bioluminescent imaging to investigate synergism between Streptococcus pneumoniae and influenza A virus in infant mice.

Short KR, Diavatopoulos DA, Reading PC, Brown LE, Rogers KL, Strugnell RA, Wijburg OL.

J Vis Exp. 2011 Apr 14;(50). pii: 2357. doi: 10.3791/2357.


Local recall responses in the stomach involving reduced regulation and expanded help mediate vaccine-induced protection against Helicobacter pylori in mice.

Becher D, Deutscher ME, Simpfendorfer KR, Wijburg OL, Pederson JS, Lew AM, Strugnell RA, Walduck AK.

Eur J Immunol. 2010 Oct;40(10):2778-90. doi: 10.1002/eji.200940219.


The role of secretory antibodies in infection immunity.

Strugnell RA, Wijburg OL.

Nat Rev Microbiol. 2010 Sep;8(9):656-67. doi: 10.1038/nrmicro2384. Epub 2010 Aug 9. Review.


The multi-copper-ion oxidase CueO of Salmonella enterica serovar Typhimurium is required for systemic virulence.

Achard ME, Tree JJ, Holden JA, Simpfendorfer KR, Wijburg OL, Strugnell RA, Schembri MA, Sweet MJ, Jennings MP, McEwan AG.

Infect Immun. 2010 May;78(5):2312-9. doi: 10.1128/IAI.01208-09. Epub 2010 Mar 15.


Different bacterial pathogens, different strategies, yet the aim is the same: evasion of intestinal dendritic cell recognition.

Bedoui S, Kupz A, Wijburg OL, Walduck AK, Rescigno M, Strugnell RA.

J Immunol. 2010 Mar 1;184(5):2237-42. doi: 10.4049/jimmunol.0902871. Review.


Influenza A virus facilitates Streptococcus pneumoniae transmission and disease.

Diavatopoulos DA, Short KR, Price JT, Wilksch JJ, Brown LE, Briles DE, Strugnell RA, Wijburg OL.

FASEB J. 2010 Jun;24(6):1789-98. doi: 10.1096/fj.09-146779. Epub 2010 Jan 22.


The major surface-associated saccharides of Klebsiella pneumoniae contribute to host cell association.

Clements A, Gaboriaud F, Duval JF, Farn JL, Jenney AW, Lithgow T, Wijburg OL, Hartland EL, Strugnell RA.

PLoS One. 2008;3(11):e3817. doi: 10.1371/journal.pone.0003817. Epub 2008 Nov 26.


Impact of prior immunological exposure on vaccine delivery by Salmonella enterica serovar Typhimurium.

Gahan ME, Webster DE, Wijburg OL, Wesselingh SL, Strugnell RA.

Vaccine. 2008 Nov 18;26(49):6212-20. doi: 10.1016/j.vaccine.2008.09.060. Epub 2008 Oct 11.


Targeting subcapsular antigens for prevention of Klebsiella pneumoniae infections.

Clements A, Jenney AW, Farn JL, Brown LE, Deliyannis G, Hartland EL, Pearse MJ, Maloney MB, Wesselingh SL, Wijburg OL, Strugnell RA.

Vaccine. 2008 Oct 16;26(44):5649-53. doi: 10.1016/j.vaccine.2008.07.100. Epub 2008 Aug 24.


Macrophages are mediators of gastritis in acute Helicobacter pylori infection in C57BL/6 mice.

Kaparakis M, Walduck AK, Price JD, Pedersen JS, van Rooijen N, Pearse MJ, Wijburg OL, Strugnell RA.

Infect Immun. 2008 May;76(5):2235-9. doi: 10.1128/IAI.01481-07. Epub 2008 Mar 10.


Reactive oxygen species are the major antibacterials against Salmonella Typhimurium purine auxotrophs in the phagosome of RAW 264.7 cells.

Mantena RK, Wijburg OL, Vindurampulle C, Bennett-Wood VR, Walduck A, Drummond GR, Davies JK, Robins-Browne RM, Strugnell RA.

Cell Microbiol. 2008 May;10(5):1058-73. Epub 2007 Dec 6.


CD8+ T cells are associated with severe gastritis in Helicobacter pylori-infected mice in the absence of CD4+ T cells.

Tan MP, Pedersen J, Zhan Y, Lew AM, Pearse MJ, Wijburg OL, Strugnell RA.

Infect Immun. 2008 Mar;76(3):1289-97. Epub 2007 Nov 19.


Gamma interferon-independent effects of interleukin-12 on immunity to Salmonella enterica serovar Typhimurium.

Price JD, Simpfendorfer KR, Mantena RR, Holden J, Heath WR, van Rooijen N, Strugnell RA, Wijburg OL.

Infect Immun. 2007 Dec;75(12):5753-62. Epub 2007 Sep 17.


Secondary acylation of Klebsiella pneumoniae lipopolysaccharide contributes to sensitivity to antibacterial peptides.

Clements A, Tull D, Jenney AW, Farn JL, Kim SH, Bishop RE, McPhee JB, Hancock RE, Hartland EL, Pearse MJ, Wijburg OL, Jackson DC, McConville MJ, Strugnell RA.

J Biol Chem. 2007 May 25;282(21):15569-77. Epub 2007 Mar 19.


Secretory antibodies reduce systemic antibody responses against the gastrointestinal commensal flora.

Sait LC, Galic M, Price JD, Simpfendorfer KR, Diavatopoulos DA, Uren TK, Janssen PH, Wijburg OL, Strugnell RA.

Int Immunol. 2007 Mar;19(3):257-65. Epub 2007 Jan 24.


Chronic Helicobacter pylori infection does not significantly alter the microbiota of the murine stomach.

Tan MP, Kaparakis M, Galic M, Pedersen J, Pearse M, Wijburg OL, Janssen PH, Strugnell RA.

Appl Environ Microbiol. 2007 Feb;73(3):1010-3. Epub 2006 Dec 1.


Seroepidemiology of Klebsiella pneumoniae in an Australian Tertiary Hospital and its implications for vaccine development.

Jenney AW, Clements A, Farn JL, Wijburg OL, McGlinchey A, Spelman DW, Pitt TL, Kaufmann ME, Liolios L, Moloney MB, Wesselingh SL, Strugnell RA.

J Clin Microbiol. 2006 Jan;44(1):102-7.


Innate secretory antibodies protect against natural Salmonella typhimurium infection.

Wijburg OL, Uren TK, Simpfendorfer K, Johansen FE, Brandtzaeg P, Strugnell RA.

J Exp Med. 2006 Jan 23;203(1):21-6. Epub 2006 Jan 3.


Mucosal Immune Responses to Escherichia coli and Salmonella Infections.

Wijburg OL, Strugnell RA.

EcoSal Plus. 2006 Jan;2(1). doi: 10.1128/ecosalplus.8.8.12.


Vaccine-induced protection against gastrointestinal bacterial infections in the absence of secretory antibodies.

Uren TK, Wijburg OL, Simmons C, Johansen FE, Brandtzaeg P, Strugnell RA.

Eur J Immunol. 2005 Jan;35(1):180-8.


Responses against complex antigens in various models of CD4 T-cell deficiency: surprises from an anti-CD4 antibody transgenic mouse.

Zhan Y, Brown LE, Deliyannis G, Seah S, Wijburg OL, Price J, Strugnell RA, O'Connell PJ, Lew AM.

Immunol Res. 2004;30(1):1-14. Review.


Role of the polymeric Ig receptor in mucosal B cell homeostasis.

Uren TK, Johansen FE, Wijburg OL, Koentgen F, Brandtzaeg P, Strugnell RA.

J Immunol. 2003 Mar 1;170(5):2531-9.


Dual role for macrophages in vivo in pathogenesis and control of murine Salmonella enterica var. Typhimurium infections.

Wijburg OL, Simmons CP, van Rooijen N, Strugnell RA.

Eur J Immunol. 2000 Mar;30(3):944-53.


The role of macrophages in the induction and regulation of immunity elicited by exogenous antigens.

Wijburg OL, van den Dobbelsteen GP, Vadolas J, Sanders A, Strugnell RA, van Rooijen N.

Eur J Immunol. 1998 Feb;28(2):479-87.


Role of spleen macrophages in innate and acquired immune responses against mouse hepatitis virus strain A59.

Wijburg OL, Heemskerk MH, Boog CJ, Van Rooijen N.

Immunology. 1997 Oct;92(2):252-8.


Alveolar macrophages regulate the induction of primary cytotoxic T-lymphocyte responses during influenza virus infection.

Wijburg OL, DiNatale S, Vadolas J, van Rooijen N, Strugnell RA.

J Virol. 1997 Dec;71(12):9450-7.


Role of virus-specific CD4+ cytotoxic T cells in recovery from mouse hepatitis virus infection.

Wijburg OL, Heemskerk MH, Sanders A, Boog CJ, Van Rooijen N.

Immunology. 1996 Jan;87(1):34-41.


Macrophages in host defense mechanisms.

van Rooijen N, Wijburg OL, van den Dobbelsteen GP, Sanders A.

Curr Top Microbiol Immunol. 1996;210:159-65. Review. No abstract available.


Different growth factor requirements for human Th2 cells may reflect in vivo induced anergy.

Van Reijsen FC, Wijburg OL, Gebhardt M, Van Ieperen-Van Dijk AG, Betz S, Poellabauer EM, Thepen T, Bruijnzeel-Koomen CA, Mudde GC.

Clin Exp Immunol. 1994 Oct;98(1):151-7.


Alpha 2A-adrenergic receptors activate protein kinase C in human platelets via a pertussis toxin-sensitive G-protein.

Nieuwland R, Wijburg OL, van Willigen G, Akkerman JW.

FEBS Lett. 1994 Feb 14;339(1-2):79-83.

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