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Items: 30

1.

Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation.

Shi J, Whyte WA, Zepeda-Mendoza CJ, Milazzo JP, Shen C, Roe JS, Minder JL, Mercan F, Wang E, Eckersley-Maslin MA, Campbell AE, Kawaoka S, Shareef S, Zhu Z, Kendall J, Muhar M, Haslinger C, Yu M, Roeder RG, Wigler MH, Blobel GA, Zuber J, Spector DL, Young RA, Vakoc CR.

Genes Dev. 2013 Dec 15;27(24):2648-62. doi: 10.1101/gad.232710.113. Epub 2013 Nov 27.

2.

Genomic amplification and oncogenic properties of the KCNK9 potassium channel gene.

Mu D, Chen L, Zhang X, See LH, Koch CM, Yen C, Tong JJ, Spiegel L, Nguyen KC, Servoss A, Peng Y, Pei L, Marks JR, Lowe S, Hoey T, Jan LY, McCombie WR, Wigler MH, Powers S.

Cancer Cell. 2003 Mar;3(3):297-302.

3.

DBC2, a candidate for a tumor suppressor gene involved in breast cancer.

Hamaguchi M, Meth JL, von Klitzing C, Wei W, Esposito D, Rodgers L, Walsh T, Welcsh P, King MC, Wigler MH.

Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13647-52. Epub 2002 Oct 7.

4.

Design of a retroviral-mediated ecdysone-inducible system and its application to the expression profiling of the PTEN tumor suppressor.

Stolarov J, Chang K, Reiner A, Rodgers L, Hannon GJ, Wigler MH, Mittal V.

Proc Natl Acad Sci U S A. 2001 Nov 6;98(23):13043-8. Epub 2001 Oct 30.

5.

PTEN controls tumor-induced angiogenesis.

Wen S, Stolarov J, Myers MP, Su JD, Wigler MH, Tonks NK, Durden DL.

Proc Natl Acad Sci U S A. 2001 Apr 10;98(8):4622-7. Epub 2001 Mar 27.

6.

Molecular forceps from combinatorial libraries prevent the farnesylation of Ras by binding to its carboxyl terminus.

Dong DL, Liu R, Sherlock R, Wigler MH, Nestler HP.

Chem Biol. 1999 Mar;6(3):133-41.

7.

The lipid phosphatase activity of PTEN is critical for its tumor supressor function.

Myers MP, Pass I, Batty IH, Van der Kaay J, Stolarov JP, Hemmings BA, Wigler MH, Downes CP, Tonks NK.

Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13513-8.

8.

Signaling pathways in Ras-mediated tumorigenicity and metastasis.

Webb CP, Van Aelst L, Wigler MH, Vande Woude GF.

Proc Natl Acad Sci U S A. 1998 Jul 21;95(15):8773-8.

9.

Rapid isolation of cDNA by hybridization.

Hamaguchi M, O'Connor EA, Chen T, Parnell L, McCombie RW, Wigler MH.

Proc Natl Acad Sci U S A. 1998 Mar 31;95(7):3764-9.

10.

P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase.

Myers MP, Stolarov JP, Eng C, Li J, Wang SI, Wigler MH, Parsons R, Tonks NK.

Proc Natl Acad Sci U S A. 1997 Aug 19;94(17):9052-7.

11.

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer.

Li J, Yen C, Liaw D, Podsypanina K, Bose S, Wang SI, Puc J, Miliaresis C, Rodgers L, McCombie R, Bigner SH, Giovanella BC, Ittmann M, Tycko B, Hibshoosh H, Wigler MH, Parsons R.

Science. 1997 Mar 28;275(5308):1943-7.

12.

A role for the Ral guanine nucleotide dissociation stimulator in mediating Ras-induced transformation.

White MA, Vale T, Camonis JH, Schaefer E, Wigler MH.

J Biol Chem. 1996 Jul 12;271(28):16439-42.

13.

Evaluation of the FHIT gene in colorectal cancers.

Thiagalingam S, Lisitsyn NA, Hamaguchi M, Wigler MH, Willson JK, Markowitz SD, Leach FS, Kinzler KW, Vogelstein B.

Cancer Res. 1996 Jul 1;56(13):2936-9.

14.

Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation.

Khosravi-Far R, White MA, Westwick JK, Solski PA, Chrzanowska-Wodnicka M, Van Aelst L, Wigler MH, Der CJ.

Mol Cell Biol. 1996 Jul;16(7):3923-33.

15.

Stimulation of membrane ruffling and MAP kinase activation by distinct effectors of RAS.

Joneson T, White MA, Wigler MH, Bar-Sagi D.

Science. 1996 Feb 9;271(5250):810-2.

PMID:
8628998
16.

New polymorphic markers in the vicinity of the pearl locus on mouse chromosome 13.

Xu HP, Yanak BL, Wigler MH, Gorin MB.

Mamm Genome. 1996 Jan;7(1):16-9.

PMID:
8903722
17.
18.

Multiple Ras functions can contribute to mammalian cell transformation.

White MA, Nicolette C, Minden A, Polverino A, Van Aelst L, Karin M, Wigler MH.

Cell. 1995 Feb 24;80(4):533-41.

19.

Comparative genomic analysis of tumors: detection of DNA losses and amplification.

Lisitsyn NA, Lisitsina NM, Dalbagni G, Barker P, Sanchez CA, Gnarra J, Linehan WM, Reid BJ, Wigler MH.

Proc Natl Acad Sci U S A. 1995 Jan 3;92(1):151-5.

20.

Cooperative interaction of S. pombe proteins required for mating and morphogenesis.

Chang EC, Barr M, Wang Y, Jung V, Xu HP, Wigler MH.

Cell. 1994 Oct 7;79(1):131-41.

PMID:
7923372
21.

Direct isolation of polymorphic markers linked to a trait by genetically directed representational difference analysis.

Lisitsyn NA, Segre JA, Kusumi K, Lisitsyn NM, Nadeau JH, Frankel WN, Wigler MH, Lander ES.

Nat Genet. 1994 Jan;6(1):57-63.

PMID:
8136836
22.

Detection of genetic loss in tumors by representational difference analysis.

Lisitsyn NA, Leach FS, Vogelstein B, Wigler MH.

Cold Spring Harb Symp Quant Biol. 1994;59:585-7. No abstract available.

PMID:
7587116
23.

Ras partners.

Van Aelst L, White MA, Wigler MH.

Cold Spring Harb Symp Quant Biol. 1994;59:181-6. Review. No abstract available.

PMID:
7587068
24.

Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2.

Chardin P, Camonis JH, Gale NW, van Aelst L, Schlessinger J, Wigler MH, Bar-Sagi D.

Science. 1993 May 28;260(5112):1338-43.

PMID:
8493579
25.

Oncoproteins. GAPs in understanding Ras.

Wigler MH.

Nature. 1990 Aug 23;346(6286):696-7. No abstract available.

PMID:
2201920
26.

Three human transforming genes are related to the viral ras oncogenes.

Shimizu K, Goldfarb M, Suard Y, Perucho M, Li Y, Kamata T, Feramisco J, Stavnezer E, Fogh J, Wigler MH.

Proc Natl Acad Sci U S A. 1983 Apr;80(8):2112-6.

27.

The inheritance of methylation patterns in vertebrates.

Wigler MH.

Cell. 1981 May;24(2):285-6. No abstract available.

PMID:
7195315
28.

Nucleosomes in metaphase chromosomes.

Wigler MH, Axel R.

Nucleic Acids Res. 1976 Jun;3(6):1463-71.

29.

Enucleation of mammalian cells in suspension.

Wigler MH, Neugut AI, Weinstein IB.

Methods Cell Biol. 1976;14:87-93. No abstract available.

PMID:
794633
30.

A preparative method for obtaining enucleated mammalian cells.

Wigler MH, Weinstein IB.

Biochem Biophys Res Commun. 1975 Apr 7;63(3):669-74. No abstract available.

PMID:
1169063

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