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Items: 1 to 50 of 100

1.

A suite of automated tools to quantify hand and wrist motor function after cervical spinal cord injury.

Grasse KM, Hays SA, Rahebi KC, Warren VS, Garcia EA, Wigginton JG, Kilgard MP, Rennaker RL 2nd.

J Neuroeng Rehabil. 2019 Apr 11;16(1):48. doi: 10.1186/s12984-019-0518-8.

2.

Differential network enrichment analysis reveals novel lipid pathways in chronic kidney disease.

Ma J, Karnovsky A, Afshinnia F, Wigginton J, Rader DJ, Natarajan L, Sharma K, Porter AC, Rahman M, He J, Hamm L, Shafi T, Gipson D, Gadegbeku C, Feldman H, Michailidis G, Pennathur S.

Bioinformatics. 2019 Sep 15;35(18):3441-3452. doi: 10.1093/bioinformatics/btz114.

PMID:
30887029
3.

Vagus Nerve Stimulation Paired With Upper Limb Rehabilitation After Chronic Stroke.

Kimberley TJ, Pierce D, Prudente CN, Francisco GE, Yozbatiran N, Smith P, Tarver B, Engineer ND, Alexander Dickie D, Kline DK, Wigginton JG, Cramer SC, Dawson J.

Stroke. 2018 Nov;49(11):2789-2792. doi: 10.1161/STROKEAHA.118.022279.

4.

Paper-Based Surface-Enhanced Raman Scattering Lateral Flow Strip for Detection of Neuron-Specific Enolase in Blood Plasma.

Gao X, Zheng P, Kasani S, Wu S, Yang F, Lewis S, Nayeem S, Engler-Chiurazzi EB, Wigginton JG, Simpkins JW, Wu N.

Anal Chem. 2017 Sep 19;89(18):10104-10110. doi: 10.1021/acs.analchem.7b03015. Epub 2017 Sep 1.

5.

Identifying baseline immune-related biomarkers to predict clinical outcome of immunotherapy.

Gnjatic S, Bronte V, Brunet LR, Butler MO, Disis ML, Galon J, Hakansson LG, Hanks BA, Karanikas V, Khleif SN, Kirkwood JM, Miller LD, Schendel DJ, Tanneau I, Wigginton JM, Butterfield LH.

J Immunother Cancer. 2017 May 16;5:44. doi: 10.1186/s40425-017-0243-4. eCollection 2017. Review.

6.

Combination immunotherapy: a road map.

Ott PA, Hodi FS, Kaufman HL, Wigginton JM, Wolchok JD.

J Immunother Cancer. 2017 Feb 21;5:16. doi: 10.1186/s40425-017-0218-5. eCollection 2017. Review.

7.

The association of maximum Troponin values post out-of-hospital cardiac arrest with electrocardiographic findings, cardiac reperfusion procedures and survival to discharge: A sub-study of ROC PRIMED.

Morrison LJ, Devlin SM, Kontos MC, Cheskes S, Aufderheide TP, Christenson J, Ornato JP, Stiell IG, Rac VE, Thomas AJ, Wigginton JG, Dorian P; Resuscitation Outcomes Consortium Investigators.

Resuscitation. 2017 Feb;111:82-89. doi: 10.1016/j.resuscitation.2016.12.004. Epub 2016 Dec 14.

PMID:
27988273
8.

Overall Survival and Long-Term Safety of Nivolumab (Anti-Programmed Death 1 Antibody, BMS-936558, ONO-4538) in Patients With Previously Treated Advanced Non-Small-Cell Lung Cancer.

Gettinger SN, Horn L, Gandhi L, Spigel DR, Antonia SJ, Rizvi NA, Powderly JD, Heist RS, Carvajal RD, Jackman DM, Sequist LV, Smith DC, Leming P, Carbone DP, Pinder-Schenck MC, Topalian SL, Hodi FS, Sosman JA, Sznol M, McDermott DF, Pardoll DM, Sankar V, Ahlers CM, Salvati M, Wigginton JM, Hellmann MD, Kollia GD, Gupta AK, Brahmer JR.

J Clin Oncol. 2015 Jun 20;33(18):2004-12. doi: 10.1200/JCO.2014.58.3708. Epub 2015 Apr 20.

9.

Professor Jon Wigginton: where we are standing in immunotherapy.

Wigginton J, Li GS.

Chin Clin Oncol. 2015 Mar;4(1):16. doi: 10.3978/j.issn.2304-3865.2014.01.01. No abstract available.

10.

Survival, Durable Response, and Long-Term Safety in Patients With Previously Treated Advanced Renal Cell Carcinoma Receiving Nivolumab.

McDermott DF, Drake CG, Sznol M, Choueiri TK, Powderly JD, Smith DC, Brahmer JR, Carvajal RD, Hammers HJ, Puzanov I, Hodi FS, Kluger HM, Topalian SL, Pardoll DM, Wigginton JM, Kollia GD, Gupta A, McDonald D, Sankar V, Sosman JA, Atkins MB.

J Clin Oncol. 2015 Jun 20;33(18):2013-20. doi: 10.1200/JCO.2014.58.1041. Epub 2015 Mar 30.

11.

Out-of-hospital cardiac arrest survival improving over time: Results from the Resuscitation Outcomes Consortium (ROC).

Daya MR, Schmicker RH, Zive DM, Rea TD, Nichol G, Buick JE, Brooks S, Christenson J, MacPhee R, Craig A, Rittenberger JC, Davis DP, May S, Wigginton J, Wang H; Resuscitation Outcomes Consortium Investigators.

Resuscitation. 2015 Jun;91:108-15. doi: 10.1016/j.resuscitation.2015.02.003. Epub 2015 Feb 9.

12.

Sex- and gender-specific research priorities in cardiovascular resuscitation: proceedings from the 2014 Academic Emergency Medicine Consensus Conference Cardiovascular Resuscitation Research Workgroup.

Wigginton JG, Perman SM, Barr GC, McGregor AJ, Miller AC, Napoli AM, Safdar B, Weaver KR, Deutsch S, Kayea T, Becker L.

Acad Emerg Med. 2014 Dec;21(12):1343-9. doi: 10.1111/acem.12541. Erratum in: Acad Emerg Med. 2015 Apr;22(4):497. Napoli, Anthony F [corrected to Napoli, Anthony M].

13.

Bulk derivatization and direct injection of human cerebrospinal fluid for trace-level quantification of endogenous estrogens using trap-and-elute liquid chromatography with tandem mass spectrometry.

Fan H, Papouskova B, Lemr K, Wigginton JG, Schug KA.

J Sep Sci. 2014 Aug;37(15):2010-7. doi: 10.1002/jssc.201400165. Epub 2014 Jul 1.

PMID:
24824590
14.

Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab.

Topalian SL, Sznol M, McDermott DF, Kluger HM, Carvajal RD, Sharfman WH, Brahmer JR, Lawrence DP, Atkins MB, Powderly JD, Leming PD, Lipson EJ, Puzanov I, Smith DC, Taube JM, Wigginton JM, Kollia GD, Gupta A, Pardoll DM, Sosman JA, Hodi FS.

J Clin Oncol. 2014 Apr 1;32(10):1020-30. doi: 10.1200/JCO.2013.53.0105. Epub 2014 Mar 3.

15.

Estrogen-provided cardiac protection following burn trauma is mediated through a reduction in mitochondria-derived DAMPs.

Yao X, Wigginton JG, Maass DL, Ma L, Carlson D, Wolf SE, Minei JP, Zang QS.

Am J Physiol Heart Circ Physiol. 2014 Mar;306(6):H882-94. doi: 10.1152/ajpheart.00475.2013. Epub 2014 Jan 24.

16.

Paradoxical activation of T cells via augmented ERK signaling mediated by a RAF inhibitor.

Callahan MK, Masters G, Pratilas CA, Ariyan C, Katz J, Kitano S, Russell V, Gordon RA, Vyas S, Yuan J, Gupta A, Wigginton JM, Rosen N, Merghoub T, Jure-Kunkel M, Wolchok JD.

Cancer Immunol Res. 2014 Jan;2(1):70-9. doi: 10.1158/2326-6066.CIR-13-0160.

17.

Nivolumab plus ipilimumab in advanced melanoma.

Wolchok JD, Kluger H, Callahan MK, Postow MA, Rizvi NA, Lesokhin AM, Segal NH, Ariyan CE, Gordon RA, Reed K, Burke MM, Caldwell A, Kronenberg SA, Agunwamba BU, Zhang X, Lowy I, Inzunza HD, Feely W, Horak CE, Hong Q, Korman AJ, Wigginton JM, Gupta A, Sznol M.

N Engl J Med. 2013 Jul 11;369(2):122-33. doi: 10.1056/NEJMoa1302369. Epub 2013 Jun 2. Erratum in: N Engl J Med. 2018 Nov 29;379(22):2185.

18.

Snake, rattle, and roll.

Wigginton JB.

J Miss State Med Assoc. 2013 Mar;54(3):64-5. No abstract available.

PMID:
23705324
19.

Detection of β-amyloid oligomers as a predictor of neurological outcome after brain injury.

Gatson JW, Warren V, Abdelfattah K, Wolf S, Hynan LS, Moore C, Diaz-Arrastia R, Minei JP, Madden C, Wigginton JG.

J Neurosurg. 2013 Jun;118(6):1336-42. doi: 10.3171/2013.2.JNS121771. Epub 2013 Mar 29.

PMID:
23540266
20.

Resveratrol decreases inflammation in the brain of mice with mild traumatic brain injury.

Gatson JW, Liu MM, Abdelfattah K, Wigginton JG, Smith S, Wolf S, Minei JP.

J Trauma Acute Care Surg. 2013 Feb;74(2):470-4; discussion 474-5. doi: 10.1097/TA.0b013e31827e1f51.

PMID:
23354240
21.

17β-Estradiol reappropriates mass lost to the hypermetabolic state in thermally injured rats.

Abdelfattah KR, Gatson JW, Maass DL, Wolf SE, Minei JP, Wigginton JG.

J Surg Res. 2013 May 1;181(1):136-41. doi: 10.1016/j.jss.2012.06.010. Epub 2012 Jun 20.

22.

Safety and activity of anti-PD-L1 antibody in patients with advanced cancer.

Brahmer JR, Tykodi SS, Chow LQ, Hwu WJ, Topalian SL, Hwu P, Drake CG, Camacho LH, Kauh J, Odunsi K, Pitot HC, Hamid O, Bhatia S, Martins R, Eaton K, Chen S, Salay TM, Alaparthy S, Grosso JF, Korman AJ, Parker SM, Agrawal S, Goldberg SM, Pardoll DM, Gupta A, Wigginton JM.

N Engl J Med. 2012 Jun 28;366(26):2455-65. doi: 10.1056/NEJMoa1200694. Epub 2012 Jun 2.

23.

Safety, activity, and immune correlates of anti-PD-1 antibody in cancer.

Topalian SL, Hodi FS, Brahmer JR, Gettinger SN, Smith DC, McDermott DF, Powderly JD, Carvajal RD, Sosman JA, Atkins MB, Leming PD, Spigel DR, Antonia SJ, Horn L, Drake CG, Pardoll DM, Chen L, Sharfman WH, Anders RA, Taube JM, McMiller TL, Xu H, Korman AJ, Jure-Kunkel M, Agrawal S, McDonald D, Kollia GD, Gupta A, Wigginton JM, Sznol M.

N Engl J Med. 2012 Jun 28;366(26):2443-54. doi: 10.1056/NEJMoa1200690. Epub 2012 Jun 2.

24.

High-throughput molecular and histopathologic profiling of tumor tissue in a novel transplantable model of murine neuroblastoma: new tools for pediatric drug discovery.

Stauffer JK, Orentas RJ, Lincoln E, Khan T, Salcedo R, Hixon JA, Back TC, Wei JS, Patidar R, Song Y, Hurd L, Tsokos M, Lai EW, Eisenhofer G, Weiss W, Khan J, Wigginton JM.

Cancer Invest. 2012 Jun;30(5):343-63. doi: 10.3109/07357907.2012.664670.

PMID:
22571338
25.

Estrone is neuroprotective in rats after traumatic brain injury.

Gatson JW, Liu MM, Abdelfattah K, Wigginton JG, Smith S, Wolf S, Simpkins JW, Minei JP.

J Neurotrauma. 2012 Aug 10;29(12):2209-19. doi: 10.1089/neu.2011.2274. Epub 2012 May 8.

26.

Specific inhibition of mitochondrial oxidative stress suppresses inflammation and improves cardiac function in a rat pneumonia-related sepsis model.

Zang QS, Sadek H, Maass DL, Martinez B, Ma L, Kilgore JA, Williams NS, Frantz DE, Wigginton JG, Nwariaku FE, Wolf SE, Minei JP.

Am J Physiol Heart Circ Physiol. 2012 May 1;302(9):H1847-59. doi: 10.1152/ajpheart.00203.2011. Epub 2012 Mar 9.

27.

Defining the critical hurdles in cancer immunotherapy.

Fox BA, Schendel DJ, Butterfield LH, Aamdal S, Allison JP, Ascierto PA, Atkins MB, Bartunkova J, Bergmann L, Berinstein N, Bonorino CC, Borden E, Bramson JL, Britten CM, Cao X, Carson WE, Chang AE, Characiejus D, Choudhury AR, Coukos G, de Gruijl T, Dillman RO, Dolstra H, Dranoff G, Durrant LG, Finke JH, Galon J, Gollob JA, Gouttefangeas C, Grizzi F, Guida M, Håkansson L, Hege K, Herberman RB, Hodi FS, Hoos A, Huber C, Hwu P, Imai K, Jaffee EM, Janetzki S, June CH, Kalinski P, Kaufman HL, Kawakami K, Kawakami Y, Keilholtz U, Khleif SN, Kiessling R, Kotlan B, Kroemer G, Lapointe R, Levitsky HI, Lotze MT, Maccalli C, Maio M, Marschner JP, Mastrangelo MJ, Masucci G, Melero I, Melief C, Murphy WJ, Nelson B, Nicolini A, Nishimura MI, Odunsi K, Ohashi PS, O'Donnell-Tormey J, Old LJ, Ottensmeier C, Papamichail M, Parmiani G, Pawelec G, Proietti E, Qin S, Rees R, Ribas A, Ridolfi R, Ritter G, Rivoltini L, Romero PJ, Salem ML, Scheper RJ, Seliger B, Sharma P, Shiku H, Singh-Jasuja H, Song W, Straten PT, Tahara H, Tian Z, van Der Burg SH, von Hoegen P, Wang E, Welters MJ, Winter H, Withington T, Wolchok JD, Xiao W, Zitvogel L, Zwierzina H, Marincola FM, Gajewski TF, Wigginton JM, Disis ML.

J Transl Med. 2011 Dec 14;9:214. doi: 10.1186/1479-5876-9-214.

28.

Advances in resuscitative trauma care.

Wigginton JG, Roppolo LP, Pepe PE.

Minerva Anestesiol. 2011 Oct;77(10):993-1002. Review.

29.

Recommendations from the iSBTc-SITC/FDA/NCI Workshop on Immunotherapy Biomarkers.

Butterfield LH, Palucka AK, Britten CM, Dhodapkar MV, Håkansson L, Janetzki S, Kawakami Y, Kleen TO, Lee PP, Maccalli C, Maecker HT, Maino VC, Maio M, Malyguine A, Masucci G, Pawelec G, Potter DM, Rivoltini L, Salazar LG, Schendel DJ, Slingluff CL Jr, Song W, Stroncek DF, Tahara H, Thurin M, Trinchieri G, van Der Burg SH, Whiteside TL, Wigginton JM, Marincola F, Khleif S, Fox BA, Disis ML.

Clin Cancer Res. 2011 May 15;17(10):3064-76. doi: 10.1158/1078-0432.CCR-10-2234. Epub 2011 May 10. Review.

30.

Investigation of the temperature stability of premarin intravenous using liquid chromatography-mass spectrometry.

Nguyen HP, Tedmon L, Li L, Wigginton JG, Maass D, Gatson JW, Simpkins JW, Schug KA.

J Pharm Biomed Anal. 2011 Jul 15;55(5):1218-22. doi: 10.1016/j.jpba.2011.03.003. Epub 2011 Mar 9.

PMID:
21444176
31.

Rationale for routine and immediate administration of intravenous estrogen for all critically ill and injured patients.

Wigginton JG, Pepe PE, Idris AH.

Crit Care Med. 2010 Oct;38(10 Suppl):S620-9. doi: 10.1097/CCM.0b013e3181f243a9.

PMID:
21164406
32.

Simultaneous quantification of four native estrogen hormones at trace levels in human cerebrospinal fluid using liquid chromatography-tandem mass spectrometry.

Nguyen HP, Li L, Gatson JW, Maass D, Wigginton JG, Simpkins JW, Schug KA.

J Pharm Biomed Anal. 2011 Mar 25;54(4):830-7. doi: 10.1016/j.jpba.2010.11.014. Epub 2010 Nov 19.

PMID:
21145681
33.

Preventing severe hypoxia during emergent intubation: is nasopharyngeal oxygenation the answer?

Roppolo LP, Wigginton JG.

Crit Care. 2010;14(6):1005. doi: 10.1186/cc9197. Epub 2010 Nov 3. Review.

34.

Aromatase is increased in astrocytes in the presence of elevated pressure.

Gatson JW, Simpkins JW, Yi KD, Idris AH, Minei JP, Wigginton JG.

Endocrinology. 2011 Jan;152(1):207-13. doi: 10.1210/en.2010-0724. Epub 2010 Nov 3.

35.

Anti-tumour synergy of cytotoxic chemotherapy and anti-CD40 plus CpG-ODN immunotherapy through repolarization of tumour-associated macrophages.

Buhtoiarov IN, Sondel PM, Wigginton JM, Buhtoiarova TN, Yanke EM, Mahvi DA, Rakhmilevich AL.

Immunology. 2011 Feb;132(2):226-39. doi: 10.1111/j.1365-2567.2010.03357.x. Epub 2010 Oct 13.

36.

Intravenous fluid resuscitation for the trauma patient.

Roppolo LP, Wigginton JG, Pepe PE.

Curr Opin Crit Care. 2010 Aug;16(4):283-8. doi: 10.1097/MCC.0b013e32833bf774. Review.

PMID:
20601865
37.

Burn serum causes a CD14-dependent mitochondrial damage in primary cardiomyocytes.

Zang QS, Maass DL, Wigginton JG, Barber RC, Martinez B, Idris AH, Horton JW, Nwariaku FE.

Am J Physiol Heart Circ Physiol. 2010 Jun;298(6):H1951-8. doi: 10.1152/ajpheart.00927.2009. Epub 2010 Mar 26.

38.

Widespread distribution of knockdown resistance mutations in the bed bug, Cimex lectularius (Hemiptera: Cimicidae), populations in the United States.

Zhu F, Wigginton J, Romero A, Moore A, Ferguson K, Palli R, Potter MF, Haynes KF, Palli SR.

Arch Insect Biochem Physiol. 2010 Apr;73(4):245-57. doi: 10.1002/arch.20355.

PMID:
20301216
39.

Retention behavior of estrogen metabolites on hydrophilic interaction chromatography stationary phases.

Nguyen HP, Yang SH, Wigginton JG, Simpkins JW, Schug KA.

J Sep Sci. 2010 Mar;33(6-7):793-802. doi: 10.1002/jssc.200900680.

PMID:
20201045
40.

Sex, drugs and R&R (resuscitation & reanimation).

Wigginton JG, Pepe PE, Idris AH.

JEMS. 2010 Jan;35(1):S21-3. No abstract available.

PMID:
20169660
41.

Synthesis of Sulfur-Containing Aryl and Heteroaryl Vinyls via Suzuki-Miyaura Cross-Coupling for the Preparation of SERS-Active Polymers.

Perez-Pineiro R, Dai S, Alvarez-Puebla R, Wigginton J, Al-Hourani BJ, Fenniri H.

Tetrahedron Lett. 2009 Sep 30;50(39):5467-5469.

42.

Microemboli are not associated with delirium after coronary artery bypass graft surgery.

Rudolph JL, Babikian VL, Treanor P, Pochay VE, Wigginton JB, Crittenden MD, Marcantonio ER.

Perfusion. 2009 Nov;24(6):409-15. doi: 10.1177/0267659109358207.

43.

Estrogen treatment following severe burn injury reduces brain inflammation and apoptotic signaling.

Gatson JW, Maass DL, Simpkins JW, Idris AH, Minei JP, Wigginton JG.

J Neuroinflammation. 2009 Oct 22;6:30. doi: 10.1186/1742-2094-6-30.

44.

Emerging concepts in biomarker discovery; the US-Japan Workshop on Immunological Molecular Markers in Oncology.

Tahara H, Sato M, Thurin M, Wang E, Butterfield LH, Disis ML, Fox BA, Lee PP, Khleif SN, Wigginton JM, Ambs S, Akutsu Y, Chaussabel D, Doki Y, Eremin O, Fridman WH, Hirohashi Y, Imai K, Jacobson J, Jinushi M, Kanamoto A, Kashani-Sabet M, Kato K, Kawakami Y, Kirkwood JM, Kleen TO, Lehmann PV, Liotta L, Lotze MT, Maio M, Malyguine A, Masucci G, Matsubara H, Mayrand-Chung S, Nakamura K, Nishikawa H, Palucka AK, Petricoin EF, Pos Z, Ribas A, Rivoltini L, Sato N, Shiku H, Slingluff CL, Streicher H, Stroncek DF, Takeuchi H, Toyota M, Wada H, Wu X, Wulfkuhle J, Yaguchi T, Zeskind B, Zhao Y, Zocca MB, Marincola FM.

J Transl Med. 2009 Jun 17;7:45. doi: 10.1186/1479-5876-7-45.

45.

Revolving back to the basics in cardiopulmonary resuscitation.

Roppolo LP, Wigginton JG, Pepe PE.

Minerva Anestesiol. 2009 May;75(5):301-5. Review.

46.
47.

Immunologic and therapeutic synergy of IL-27 and IL-2: enhancement of T cell sensitization, tumor-specific CTL reactivity and complete regression of disseminated neuroblastoma metastases in the liver and bone marrow.

Salcedo R, Hixon JA, Stauffer JK, Jalah R, Brooks AD, Khan T, Dai RM, Scheetz L, Lincoln E, Back TC, Powell D, Hurwitz AA, Sayers TJ, Kastelein R, Pavlakis GN, Felber BK, Trinchieri G, Wigginton JM.

J Immunol. 2009 Apr 1;182(7):4328-38. doi: 10.4049/jimmunol.0800471.

48.

A systematic approach to biomarker discovery; preamble to "the iSBTc-FDA taskforce on immunotherapy biomarkers".

Butterfield LH, Disis ML, Fox BA, Lee PP, Khleif SN, Thurin M, Trinchieri G, Wang E, Wigginton J, Chaussabel D, Coukos G, Dhodapkar M, Håkansson L, Janetzki S, Kleen TO, Kirkwood JM, Maccalli C, Maecker H, Maio M, Malyguine A, Masucci G, Palucka AK, Potter DM, Ribas A, Rivoltini L, Schendel D, Seliger B, Selvan S, Slingluff CL Jr, Stroncek DF, Streicher H, Wu X, Zeskind B, Zhao Y, Zocca MB, Zwierzina H, Marincola FM.

J Transl Med. 2008 Dec 23;6:81. doi: 10.1186/1479-5876-6-81.

49.

Intraoperative cerebral high-intensity transient signals and postoperative cognitive function: a systematic review.

Martin KK, Wigginton JB, Babikian VL, Pochay VE, Crittenden MD, Rudolph JL.

Am J Surg. 2009 Jan;197(1):55-63. doi: 10.1016/j.amjsurg.2007.12.060. Epub 2008 Aug 23. Review.

50.

Immunotherapy of cancer by IL-12-based cytokine combinations.

Weiss JM, Subleski JJ, Wigginton JM, Wiltrout RH.

Expert Opin Biol Ther. 2007 Nov;7(11):1705-21. Review.

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