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Items: 1 to 50 of 206

1.

MicroRNA expression in human retinal pigment epithelial (ARPE-19) cells: increased expression of microRNA-9 by N-(4-hydroxyphenyl)retinamide.

Kutty RK, Samuel W, Jaworski C, Duncan T, Nagineni CN, Raghavachari N, Wiggert B, Redmond TM.

Mol Vis. 2010 Aug 4;16:1475-86.

2.

Mitogen-activated protein kinase pathway mediates N-(4-hydroxyphenyl)retinamide-induced neuronal differentiation in the ARPE-19 human retinal pigment epithelial cell line.

Samuel W, Kutty RK, Sekhar S, Vijayasarathy C, Wiggert B, Redmond TM.

J Neurochem. 2008 Jul;106(2):591-602. doi: 10.1111/j.1471-4159.2008.05409.x. Epub 2008 Apr 10.

3.

Interphotoreceptor retinoid-binding protein is the physiologically relevant carrier that removes retinol from rod photoreceptor outer segments.

Wu Q, Blakeley LR, Cornwall MC, Crouch RK, Wiggert BN, Koutalos Y.

Biochemistry. 2007 Jul 24;46(29):8669-79. Epub 2007 Jun 30.

6.

Visual cycle and its metabolic support in gecko photoreceptors.

Kolesnikov AV, Ala-Laurila P, Shukolyukov SA, Crouch RK, Wiggert B, Estevez ME, Govardovskii VI, Cornwall MC.

Vision Res. 2007 Feb;47(3):363-74. Epub 2006 Oct 16.

8.

Visual cycle: Dependence of retinol production and removal on photoproduct decay and cell morphology.

Ala-Laurila P, Kolesnikov AV, Crouch RK, Tsina E, Shukolyukov SA, Govardovskii VI, Koutalos Y, Wiggert B, Estevez ME, Cornwall MC.

J Gen Physiol. 2006 Aug;128(2):153-69. Epub 2006 Jul 17.

9.

Immunofluorescence analysis of the expression of Norpeg (Rai14) in retinal Müller and ganglion cells.

Kutty RK, Samuel W, Chen S, Vijayasarathy C, Dun Y, Mysona B, Wiggert B, Smith SB.

Neurosci Lett. 2006 Sep 1;404(3):294-8. Epub 2006 Jun 27.

PMID:
16806700
10.

Cell density-dependent nuclear/cytoplasmic localization of NORPEG (RAI14) protein.

Kutty RK, Chen S, Samuel W, Vijayasarathy C, Duncan T, Tsai JY, Fariss RN, Carper D, Jaworski C, Wiggert B.

Biochem Biophys Res Commun. 2006 Jul 14;345(4):1333-41. Epub 2006 May 16.

PMID:
16729964
11.

Effect of visible light on normal and P23H-3 transgenic rat retinas: characterization of a novel retinoic acid derivative present in the P23H-3 retina.

Duncan T, Wiggert B, Whittaker N, Darrow R, Organisciak DT.

Photochem Photobiol. 2006 May-Jun;82(3):741-5.

PMID:
16336041
12.
13.

The immunomodulator vasoactive intestinal peptide (VIP) does not affect experimental autoimmune uveitis (EAU) in B10.RIII mice.

Chen J, Vistica B, Wiggert B, Chan CC, Gery I.

Ocul Immunol Inflamm. 2005 Feb;13(1):13-7.

PMID:
15804764
14.

Physiological and microfluorometric studies of reduction and clearance of retinal in bleached rod photoreceptors.

Tsina E, Chen C, Koutalos Y, Ala-Laurila P, Tsacopoulos M, Wiggert B, Crouch RK, Cornwall MC.

J Gen Physiol. 2004 Oct;124(4):429-43.

15.

Regulation of the visual cycle: retinol dehydrogenase and retinol fluorescence measurements in vertebrate retina.

Cornwall MC, Tsina E, Crouch RK, Wiggert B, Chen C, Koutalos Y.

Adv Exp Med Biol. 2003;533:353-60. Review. No abstract available.

PMID:
15180285
16.

An immunologically privileged retinal antigen elicits tolerance: major role for central selection mechanisms.

Avichezer D, Grajewski RS, Chan CC, Mattapallil MJ, Silver PB, Raber JA, Liou GI, Wiggert B, Lewis GM, Donoso LA, Caspi RR.

J Exp Med. 2003 Dec 1;198(11):1665-76.

17.

Interphotoreceptor retinoid-binding protein (IRBP)-deficient C57BL/6 mice have enhanced immunological and immunopathogenic responses to IRBP and an altered recognition of IRBP epitopes.

Avichezer D, Liou GI, Chan CC, Lewis GM, Wiggert B, Donoso LA, Nickerson JM, Crawford MA, Caspi RR.

J Autoimmun. 2003 Nov;21(3):185-94.

PMID:
14599843
18.

Transforming growth factor-beta induces expression of vascular endothelial growth factor in human retinal pigment epithelial cells: involvement of mitogen-activated protein kinases.

Nagineni CN, Samuel W, Nagineni S, Pardhasaradhi K, Wiggert B, Detrick B, Hooks JJ.

J Cell Physiol. 2003 Dec;197(3):453-62.

PMID:
14566975
19.

A humanized model of experimental autoimmune uveitis in HLA class II transgenic mice.

Pennesi G, Mattapallil MJ, Sun SH, Avichezer D, Silver PB, Karabekian Z, David CS, Hargrave PA, McDowell JH, Smith WC, Wiggert B, Donoso LA, Chan CC, Caspi RR.

J Clin Invest. 2003 Apr;111(8):1171-80.

20.

Differentiation of human retinal pigment epithelial cells into neuronal phenotype by N-(4-hydroxyphenyl)retinamide.

Chen S, Samuel W, Fariss RN, Duncan T, Kutty RK, Wiggert B.

J Neurochem. 2003 Mar;84(5):972-81.

21.

Susceptibility to retinal light damage in transgenic rats with rhodopsin mutations.

Organisciak DT, Darrow RM, Barsalou L, Kutty RK, Wiggert B.

Invest Ophthalmol Vis Sci. 2003 Feb;44(2):486-92.

PMID:
12556372
22.

Chemokine gene expression in iris-ciliary body during experimental autoimmune uveoretinitis.

Ohta K, Yamagami S, Wiggert B, Dana MR, Streilein JW.

Curr Eye Res. 2002 Jun;24(6):451-7.

PMID:
12525972
23.

Methimazole protects from experimental autoimmune uveitis (EAU) by inhibiting antigen presenting cell function and reducing antigen priming.

Wang P, Sun SH, Silver PB, Chan CC, Agarwal RK, Wiggert B, Kohn LD, Jamieson GA Jr, Caspi RR.

J Leukoc Biol. 2003 Jan;73(1):57-64.

PMID:
12525562
24.

Transforming growth factor-beta regulates stearoyl coenzyme A desaturase expression through a Smad signaling pathway.

Samuel W, Nagineni CN, Kutty RK, Parks WT, Gordon JS, Prouty SM, Hooks JJ, Wiggert B.

J Biol Chem. 2002 Jan 4;277(1):59-66. Epub 2001 Oct 24.

25.

Immune response to retinal antigens in patients with gyrate atrophy and other hereditary retinal dystrophies.

Tamm SA, Whitcup SM, Gery I, Wiggert B, Nussenblatt RB, Kaiser-Kupfer MI.

Ocul Immunol Inflamm. 2001 Jun;9(2):75-84.

PMID:
11449323
26.

Regulation of stearoyl coenzyme A desaturase expression in human retinal pigment epithelial cells by retinoic acid.

Samuel W, Kutty RK, Nagineni S, Gordon JS, Prouty SM, Chandraratna RA, Wiggert B.

J Biol Chem. 2001 Aug 3;276(31):28744-50. Epub 2001 Jun 7.

27.

Oxidative stress induces heme oxygenase-1 immunoreactivity in Müller cells of mouse retina in organ culture.

Ulyanova T, Szél A, Kutty RK, Wiggert B, Caffé AR, Chader GJ, van Veen T.

Invest Ophthalmol Vis Sci. 2001 May;42(6):1370-4.

PMID:
11328753
28.

Identification, expression, and substrate specificity of a mammalian beta-carotene 15,15'-dioxygenase.

Redmond TM, Gentleman S, Duncan T, Yu S, Wiggert B, Gantt E, Cunningham FX Jr.

J Biol Chem. 2001 Mar 2;276(9):6560-5. Epub 2000 Nov 22.

29.
30.

Circadian-dependent retinal light damage in rats.

Organisciak DT, Darrow RM, Barsalou L, Kutty RK, Wiggert B.

Invest Ophthalmol Vis Sci. 2000 Nov;41(12):3694-701.

PMID:
11053264
31.
32.

Molecular characterization and developmental expression of NORPEG, a novel gene induced by retinoic acid.

Kutty RK, Kutty G, Samuel W, Duncan T, Bridges CC, El-Sherbeeny A, Nagineni CN, Smith SB, Wiggert B.

J Biol Chem. 2001 Jan 26;276(4):2831-40. Epub 2000 Oct 19.

33.

Residues 1-20 of IRBP and whole IRBP elicit different uveitogenic and immunological responses in interferon gamma deficient mice.

Avichezer D, Chan CC, Silver PB, Wiggert B, Caspi RR.

Exp Eye Res. 2000 Aug;71(2):111-8.

PMID:
10930316
34.

Xenopus IRBP, a phylogenetically remote protein, is uveitogenic in Lewis rats.

Gelderman MP, Gonzalez-Fernandez F, Baer CA, Wiggert B, Chan CC, Vistica BP, Gery I.

Exp Eye Res. 2000 Jun;70(6):731-6.

PMID:
10843777
35.

Copolymer 1 inhibits experimental autoimmune uveoretinitis.

Zhang M, Chan CC, Vistica B, Hung V, Wiggert B, Gery I.

J Neuroimmunol. 2000 Mar 1;103(2):189-94.

PMID:
10696914
36.

Analysis of immunomodulatory activities of aqueous humor from eyes of mice with experimental autoimmune uveitis.

Ohta K, Wiggert B, Yamagami S, Taylor AW, Streilein JW.

J Immunol. 2000 Feb 1;164(3):1185-92.

37.

Identification of a new epitope of human IRBP that induces autoimmune uveoretinitis in mice of the H-2b haplotype.

Avichezer D, Silver PB, Chan CC, Wiggert B, Caspi RR.

Invest Ophthalmol Vis Sci. 2000 Jan;41(1):127-31.

PMID:
10634611
38.

Transgenic expression of an immunologically privileged retinal antigen extraocularly enhances self tolerance and abrogates susceptibility to autoimmune uveitis.

Xu H, Wawrousek EF, Redmond TM, Nickerson JM, Wiggert B, Chan CC, Caspi RR.

Eur J Immunol. 2000 Jan;30(1):272-8.

39.
40.

Effects of experimental ocular inflammation on ocular immune privilege.

Ohta K, Wiggert B, Taylor AW, Streilein JW.

Invest Ophthalmol Vis Sci. 1999 Aug;40(9):2010-8.

PMID:
10440255
42.

[Experimental autoimmune uveitis. Characterization of retina infiltrating cells].

Zierhut M, Wild U, Roser R, Wiggert B, Thiel HJ, Stiemer R.

Ophthalmologe. 1999 Apr;96(4):252-6. German.

PMID:
10409853
43.
44.
45.

Mice deficient in inducible nitric oxide synthase are susceptible to experimental autoimmune uveoretinitis.

Silver PB, Tarrant TK, Chan CC, Wiggert B, Caspi RR.

Invest Ophthalmol Vis Sci. 1999 May;40(6):1280-4.

PMID:
10235566
46.

Protective effect of the type IV phosphodiesterase inhibitor rolipram in EAU: protection is independent of IL-10-inducing activity.

Xu H, Strassmann G, Chan CC, Rizzo LV, Silver PB, Wiggert B, Caspi RR.

Invest Ophthalmol Vis Sci. 1999 Apr;40(5):942-50.

PMID:
10102291
47.

IL-4 and IL-10 are both required for the induction of oral tolerance.

Rizzo LV, Morawetz RA, Miller-Rivero NE, Choi R, Wiggert B, Chan CC, Morse HC 3rd, Nussenblatt RB, Caspi RR.

J Immunol. 1999 Mar 1;162(5):2613-22.

48.

Pregnancy ameliorates induction and expression of experimental autoimmune uveitis.

Agarwal RK, Chan CC, Wiggert B, Caspi RR.

J Immunol. 1999 Mar 1;162(5):2648-54.

49.

[High endothelial venules. Kinetics of the expression in IRBP-induced experimental autoimmune uveitis].

Stiemer R, Duijvestijn A, Wiggert B, Whitcup S, Zierhut M.

Ophthalmologe. 1999 Jan;96(1):40-4. German.

PMID:
10067334
50.

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