Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 187

1.

Profiling antimicrobial peptides from the medical maggot Lucilia sericata as potential antibiotics for MDR Gram-negative bacteria.

Hirsch R, Wiesner J, Marker A, Pfeifer Y, Bauer A, Hammann PE, Vilcinskas A.

J Antimicrob Chemother. 2018 Oct 1. doi: 10.1093/jac/dky386. [Epub ahead of print]

PMID:
30272195
2.

Biological Profiling of Coleoptericins and Coleoptericin-Like Antimicrobial Peptides from the Invasive Harlequin Ladybird Harmonia axyridis.

Hirsch R, Wiesner J, Marker A, Bauer A, Hammann PE, Vilcinskas A.

Adv Exp Med Biol. 2018 Sep 30. doi: 10.1007/5584_2018_276. [Epub ahead of print]

PMID:
30269257
3.

Glycine Amidinotransferase (GATM), Renal Fanconi Syndrome, and Kidney Failure.

Reichold M, Klootwijk ED, Reinders J, Otto EA, Milani M, Broeker C, Laing C, Wiesner J, Devi S, Zhou W, Schmitt R, Tegtmeier I, Sterner C, Doellerer H, Renner K, Oefner PJ, Dettmer K, Simbuerger JM, Witzgall R, Stanescu HC, Dumitriu S, Iancu D, Patel V, Mozere M, Tekman M, Jaureguiberry G, Issler N, Kesselheim A, Walsh SB, Gale DP, Howie AJ, Martins JR, Hall AM, Kasgharian M, O'Brien K, Ferreira CR, Atwal PS, Jain M, Hammers A, Charles-Edwards G, Choe CU, Isbrandt D, Cebrian-Serrano A, Davies B, Sandford RN, Pugh C, Konecki DS, Povey S, Bockenhauer D, Lichter-Konecki U, Gahl WA, Unwin RJ, Warth R, Kleta R.

J Am Soc Nephrol. 2018 Jul;29(7):1849-1858. doi: 10.1681/ASN.2017111179. Epub 2018 Apr 13.

PMID:
29654216
4.

Strategies for the construction of insect P450 fusion enzymes.

Talmann L, Wiesner J, Vilcinskas A.

Z Naturforsch C. 2017 Sep 26;72(9-10):405-415. doi: 10.1515/znc-2017-0041.

PMID:
28866653
5.

Herbal medicinal products in pregnancy - which data are available?

Wiesner J, Knöss W.

Reprod Toxicol. 2017 Sep;72:142-152. doi: 10.1016/j.reprotox.2017.06.046. Epub 2017 Jun 17. Review.

PMID:
28633984
6.

In Vitro Antimicrobial Efficacy of Tobramycin Against Staphylococcus aureus Biofilms in Combination With or Without DNase I and/or Dispersin B: A Preliminary Investigation.

Waryah CB, Wells K, Ulluwishewa D, Chen-Tan N, Gogoi-Tiwari J, Ravensdale J, Costantino P, Gökçen A, Vilcinskas A, Wiesner J, Mukkur T.

Microb Drug Resist. 2017 Apr;23(3):384-390. doi: 10.1089/mdr.2016.0100. Epub 2016 Oct 18.

PMID:
27754780
7.

FR-900098, an antimalarial development candidate that inhibits the non-mevalonate isoprenoid biosynthesis pathway, shows no evidence of acute toxicity and genotoxicity.

Wiesner J, Ziemann C, Hintz M, Reichenberg A, Ortmann R, Schlitzer M, Fuhst R, Timmesfeld N, Vilcinskas A, Jomaa H.

Virulence. 2016 Aug 17;7(6):718-28. doi: 10.1080/21505594.2016.1195537. Epub 2016 Jun 3.

8.

Molecular mechanism of thermosensory function of human heat shock transcription factor Hsf1.

Hentze N, Le Breton L, Wiesner J, Kempf G, Mayer MP.

Elife. 2016 Jan 19;5. pii: e11576. doi: 10.7554/eLife.11576.

9.

Expression and characterization of a recombinant i-type lysozyme from the harlequin ladybird beetle Harmonia axyridis.

Beckert A, Wiesner J, Schmidtberg H, Lehmann R, Baumann A, Vogel H, Vilcinskas A.

Insect Mol Biol. 2016 Jun;25(3):202-15. doi: 10.1111/imb.12213. Epub 2016 Jan 18.

PMID:
26778648
10.

A Jonah-like chymotrypsin from the therapeutic maggot Lucilia sericata plays a role in wound debridement and coagulation.

Pöppel AK, Kahl M, Baumann A, Wiesner J, Gökçen A, Beckert A, Preissner KT, Vilcinskas A, Franta Z.

Insect Biochem Mol Biol. 2016 Mar;70:138-47. doi: 10.1016/j.ibmb.2015.11.012. Epub 2016 Jan 7.

PMID:
26773746
11.

Maggot excretion products from the blowfly Lucilia sericata contain contact phase/intrinsic pathway-like proteases with procoagulant functions.

Kahl M, Gökçen A, Fischer S, Bäumer M, Wiesner J, Lochnit G, Wygrecka M, Vilcinskas A, Preissner KT.

Thromb Haemost. 2015 Aug;114(2):277-88. doi: 10.1160/TH14-06-0499. Epub 2015 May 7.

PMID:
25948398
12.

Insect antimicrobial peptides show potentiating functional interactions against Gram-negative bacteria.

Rahnamaeian M, Cytryńska M, Zdybicka-Barabas A, Dobslaff K, Wiesner J, Twyman RM, Zuchner T, Sadd BM, Regoes RR, Schmid-Hempel P, Vilcinskas A.

Proc Biol Sci. 2015 May 7;282(1806):20150293. doi: 10.1098/rspb.2015.0293.

13.

Advanced mass spectrometry workflows for analyzing disulfide bonds in biologics.

Wiesner J, Resemann A, Evans C, Suckau D, Jabs W.

Expert Rev Proteomics. 2015 Apr;12(2):115-23. doi: 10.1586/14789450.2015.1018896. Epub 2015 Feb 26. Review.

PMID:
25720436
14.

Antimicrobial peptides expressed in medicinal maggots of the blow fly Lucilia sericata show combinatorial activity against bacteria.

Pöppel AK, Vogel H, Wiesner J, Vilcinskas A.

Antimicrob Agents Chemother. 2015 May;59(5):2508-14. doi: 10.1128/AAC.05180-14. Epub 2015 Feb 9.

15.

Two c-type lysozymes boost the innate immune system of the invasive ladybird Harmonia axyridis.

Beckert A, Wiesner J, Baumann A, Pöppel AK, Vogel H, Vilcinskas A.

Dev Comp Immunol. 2015 Apr;49(2):303-12. doi: 10.1016/j.dci.2014.11.020. Epub 2014 Dec 3.

PMID:
25479015
16.

Future visions for traditional and herbal medicinal products--a global practice for evaluation and regulation?

Wiesner J, Knöss W.

J Ethnopharmacol. 2014 Dec 2;158 Pt B:516-8. doi: 10.1016/j.jep.2014.08.015. Epub 2014 Aug 22.

PMID:
25152297
17.

Challenges of safety evaluation.

Wiesner J.

J Ethnopharmacol. 2014 Dec 2;158 Pt B:467-70. doi: 10.1016/j.jep.2014.08.013. Epub 2014 Aug 21.

PMID:
25150528
18.

Assessment of genotoxicity of herbal medicinal products: application of the "bracketing and matrixing" concept using the example of Valerianae radix (valerian root).

Kelber O, Wegener T, Steinhoff B, Staiger C, Wiesner J, Knöss W, Kraft K.

Phytomedicine. 2014 Jul-Aug;21(8-9):1124-9. doi: 10.1016/j.phymed.2014.04.003. Epub 2014 May 16. Review.

19.

Lucimycin, an antifungal peptide from the therapeutic maggot of the common green bottle fly Lucilia sericata.

Pöppel AK, Koch A, Kogel KH, Vogel H, Kollewe C, Wiesner J, Vilcinskas A.

Biol Chem. 2014 Jun;395(6):649-56. doi: 10.1515/hsz-2013-0263.

PMID:
24622788
20.

Biofilm-degrading enzymes from Lysobacter gummosus.

Gökçen A, Vilcinskas A, Wiesner J.

Virulence. 2014 Apr 1;5(3):378-87. doi: 10.4161/viru.27919. Epub 2014 Feb 11.

21.

Structure of the (E)-4-hydroxy-3-methyl-but-2-enyl-diphosphate reductase from Plasmodium falciparum.

Rekittke I, Olkhova E, Wiesner J, Demmer U, Warkentin E, Jomaa H, Ermler U.

FEBS Lett. 2013 Dec 11;587(24):3968-72. doi: 10.1016/j.febslet.2013.10.029. Epub 2013 Nov 1.

22.

Changes in the transcriptome of the malaria parasite Plasmodium falciparum during the initial phase of transmission from the human to the mosquito.

Ngwa CJ, Scheuermayer M, Mair GR, Kern S, Brügl T, Wirth CC, Aminake MN, Wiesner J, Fischer R, Vilcinskas A, Pradel G.

BMC Genomics. 2013 Apr 15;14:256. doi: 10.1186/1471-2164-14-256.

23.

Methods to identify enzymes that degrade the main extracellular polysaccharide component of Staphylococcus epidermidis biofilms.

Gökçen A, Vilcinskas A, Wiesner J.

Virulence. 2013 Apr 1;4(3):260-70. doi: 10.4161/viru.23560. Epub 2013 Jan 28.

24.

Electromyographic assessment of muscle activity between genders during unilateral weight-bearing tasks using adjusted distances.

Bouillon LE, Wilhelm J, Eisel P, Wiesner J, Rachow M, Hatteberg L.

Int J Sports Phys Ther. 2012 Dec;7(6):595-605.

25.

Thujone and thujone-containing herbal medicinal and botanical products: toxicological assessment.

Pelkonen O, Abass K, Wiesner J.

Regul Toxicol Pharmacol. 2013 Feb;65(1):100-7. doi: 10.1016/j.yrtph.2012.11.002. Epub 2012 Nov 28. Review.

PMID:
23201408
26.

Harmonine, a defence compound from the harlequin ladybird, inhibits mycobacterial growth and demonstrates multi-stage antimalarial activity.

Röhrich CR, Ngwa CJ, Wiesner J, Schmidtberg H, Degenkolb T, Kollewe C, Fischer R, Pradel G, Vilcinskas A.

Biol Lett. 2012 Apr 23;8(2):308-11. doi: 10.1098/rsbl.2011.0760. Epub 2011 Sep 21.

27.

A qualitative study on patients' and physicians' visions for the future management of overweight or obesity.

Heintze C, Sonntag U, Brinck A, Huppertz M, Niewöhner J, Wiesner J, Braun V.

Fam Pract. 2012 Feb;29(1):103-9. doi: 10.1093/fampra/cmr051. Epub 2011 Sep 1.

PMID:
21885569
28.

Motivational interviewing and shared decision making in primary care.

Sonntag U, Wiesner J, Fahrenkrog S, Renneberg B, Braun V, Heintze C.

Patient Educ Couns. 2012 Apr;87(1):62-6. doi: 10.1016/j.pec.2011.07.026. Epub 2011 Aug 27.

PMID:
21873018
29.

Fosmidomycin uptake into Plasmodium and Babesia-infected erythrocytes is facilitated by parasite-induced new permeability pathways.

Baumeister S, Wiesner J, Reichenberg A, Hintz M, Bietz S, Harb OS, Roos DS, Kordes M, Friesen J, Matuschewski K, Lingelbach K, Jomaa H, Seeber F.

PLoS One. 2011 May 4;6(5):e19334. doi: 10.1371/journal.pone.0019334.

30.

NMR studies of DOXP reductoisomerase and its inhibitor complex.

Englert NE, Richter C, Wiesner J, Hintz M, Jomaa H, Schwalbe H.

Chembiochem. 2011 Feb 11;12(3):468-76. doi: 10.1002/cbic.201000465. Epub 2011 Jan 14.

PMID:
21290548
31.

Antimicrobial peptides: the ancient arm of the human immune system.

Wiesner J, Vilcinskas A.

Virulence. 2010 Sep-Oct;1(5):440-64. doi: 10.4161/viru.1.5.12983. Review.

PMID:
21178486
32.

Structure of the E-1-hydroxy-2-methyl-but-2-enyl-4-diphosphate synthase (GcpE) from Thermus thermophilus.

Rekittke I, Nonaka T, Wiesner J, Demmer U, Warkentin E, Jomaa H, Ermler U.

FEBS Lett. 2011 Feb 4;585(3):447-51. doi: 10.1016/j.febslet.2010.12.012. Epub 2010 Dec 15.

33.

RioK1, a new interactor of protein arginine methyltransferase 5 (PRMT5), competes with pICln for binding and modulates PRMT5 complex composition and substrate specificity.

Guderian G, Peter C, Wiesner J, Sickmann A, Schulze-Osthoff K, Fischer U, Grimmler M.

J Biol Chem. 2011 Jan 21;286(3):1976-86. doi: 10.1074/jbc.M110.148486. Epub 2010 Nov 16.

34.

Influence of the acetylcholinesterase active site protonation on omega loop and active site dynamics.

Wiesner J, Kříž Z, Kuča K, Jun D, Koča J.

J Biomol Struct Dyn. 2010 Dec;28(3):393-403.

PMID:
20919754
35.

Paramagnetic intermediates of (E)-4-hydroxy-3-methylbut-2-enyl diphosphate synthase (GcpE/IspG) under steady-state and pre-steady-state conditions.

Xu W, Lees NS, Adedeji D, Wiesner J, Jomaa H, Hoffman BM, Duin EC.

J Am Chem Soc. 2010 Oct 20;132(41):14509-20. doi: 10.1021/ja101764w.

PMID:
20863107
36.

A stimulatory role for the La-related protein 4B in translation.

Schäffler K, Schulz K, Hirmer A, Wiesner J, Grimm M, Sickmann A, Fischer U.

RNA. 2010 Aug;16(8):1488-99. doi: 10.1261/rna.2146910. Epub 2010 Jun 23.

37.

RlmN and Cfr are radical SAM enzymes involved in methylation of ribosomal RNA.

Yan F, LaMarre JM, Röhrich R, Wiesner J, Jomaa H, Mankin AS, Fujimori DG.

J Am Chem Soc. 2010 Mar 24;132(11):3953-64. doi: 10.1021/ja910850y.

38.

Counseling overweight in primary care: an analysis of patient-physician encounters.

Heintze C, Metz U, Hahn D, Niewöhner J, Schwantes U, Wiesner J, Braun V.

Patient Educ Couns. 2010 Jul;80(1):71-5. doi: 10.1016/j.pec.2009.10.016. Epub 2009 Dec 4.

PMID:
19962848
39.

Why acetylcholinesterase reactivators do not work in butyrylcholinesterase.

Wiesner J, Kríz Z, Kuca K, Jun D, Koca J.

J Enzyme Inhib Med Chem. 2010 Jun;25(3):318-22. doi: 10.3109/14756360903179427.

PMID:
19874115
40.
41.

Native purification of protein and RNA-protein complexes using a novel affinity procedure.

Kroiss M, Brünger KM, Wiesner J, Grimmler M, Sickmann A, Fischer U.

Fly (Austin). 2009 Jul-Sep;3(3):221-8. Epub 2009 Jul 20.

PMID:
19690462
42.

Structure of (E)-4-hydroxy-3-methyl-but-2-enyl diphosphate reductase, the terminal enzyme of the non-mevalonate pathway.

Rekittke I, Wiesner J, Röhrich R, Demmer U, Warkentin E, Xu W, Troschke K, Hintz M, No JH, Duin EC, Oldfield E, Jomaa H, Ermler U.

J Am Chem Soc. 2008 Dec 24;130(51):17206-7. doi: 10.1021/ja806668q.

43.

Application of electron transfer dissociation (ETD) for the analysis of posttranslational modifications.

Wiesner J, Premsler T, Sickmann A.

Proteomics. 2008 Nov;8(21):4466-83. doi: 10.1002/pmic.200800329. Review.

PMID:
18972526
44.

Analysis of the isoprenoid biosynthesis pathways in Listeria monocytogenes reveals a role for the alternative 2-C-methyl-D-erythritol 4-phosphate pathway in murine infection.

Begley M, Bron PA, Heuston S, Casey PG, Englert N, Wiesner J, Jomaa H, Gahan CG, Hill C.

Infect Immun. 2008 Nov;76(11):5392-401. doi: 10.1128/IAI.01376-07. Epub 2008 Sep 2.

45.

Evolution of an RNP assembly system: a minimal SMN complex facilitates formation of UsnRNPs in Drosophila melanogaster.

Kroiss M, Schultz J, Wiesner J, Chari A, Sickmann A, Fischer U.

Proc Natl Acad Sci U S A. 2008 Jul 22;105(29):10045-50. doi: 10.1073/pnas.0802287105. Epub 2008 Jul 10.

46.

The La-related protein LARP7 is a component of the 7SK ribonucleoprotein and affects transcription of cellular and viral polymerase II genes.

Markert A, Grimm M, Martinez J, Wiesner J, Meyerhans A, Meyuhas O, Sickmann A, Fischer U.

EMBO Rep. 2008 Jun;9(6):569-75. doi: 10.1038/embor.2008.72. Epub 2008 May 16.

47.

The plastid-like organelle of apicomplexan parasites as drug target.

Wiesner J, Reichenberg A, Heinrich S, Schlitzer M, Jomaa H.

Curr Pharm Des. 2008;14(9):855-71. Review.

PMID:
18473835
48.

Development of benzophenone-based farnesyltransferase inhibitors as novel antimalarials.

Kohring K, Wiesner J, Altenkämper M, Sakowski J, Silber K, Hillebrecht A, Haebel P, Dahse HM, Ortmann R, Jomaa H, Klebe G, Schlitzer M.

ChemMedChem. 2008 Aug;3(8):1217-31. doi: 10.1002/cmdc.200800043.

PMID:
18470859
49.

Studies addressing the importance of charge in the binding of fosmidomycin-like molecules to deoxyxylulosephosphate reductoisomerase.

Perruchon J, Ortmann R, Altenkämper M, Silber K, Wiesner J, Jomaa H, Klebe G, Schlitzer M.

ChemMedChem. 2008 Aug;3(8):1232-41. doi: 10.1002/cmdc.200800083.

PMID:
18470849
50.

Towards new antimalarial drugs: synthesis of non-hydrolyzable phosphate mimics as feed for a predictive QSAR study on 1-deoxy-D-xylulose-5-phosphate reductoisomerase inhibitors.

Giessmann D, Heidler P, Haemers T, Van Calenbergh S, Reichenberg A, Jomaa H, Weidemeyer C, Sanderbrand S, Wiesner J, Link A.

Chem Biodivers. 2008 Apr;5(4):643-56. doi: 10.1002/cbdv.200890060.

PMID:
18421757

Supplemental Content

Loading ...
Support Center