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Items: 21


Titan cell production in Cryptococcus neoformans reshapes the cell wall and capsule composition during infection.

Mukaremera L, Lee KK, Wagener J, Wiesner DL, Gow NAR, Nielsen K.

Cell Surf. 2018 Mar;1:15-24. doi: 10.1016/j.tcsw.2017.12.001. Epub 2018 Feb 16.


Pulmonary neuroendocrine cells amplify allergic asthma responses.

Sui P, Wiesner DL, Xu J, Zhang Y, Lee J, Van Dyken S, Lashua A, Yu C, Klein BS, Locksley RM, Deutsch G, Sun X.

Science. 2018 Jun 8;360(6393). pii: eaan8546. doi: 10.1126/science.aan8546. Epub 2018 Mar 29.


Lung Epithelial Cells Coordinate Innate Lymphocytes and Immunity against Pulmonary Fungal Infection.

Hernández-Santos N, Wiesner DL, Fites JS, McDermott AJ, Warner T, Wüthrich M, Klein BS.

Cell Host Microbe. 2018 Apr 11;23(4):511-522.e5. doi: 10.1016/j.chom.2018.02.011. Epub 2018 Mar 22.


The hepatitis C viral nonstructural protein 5A stabilizes growth-regulatory human transcripts.

Guo L, Sharma SD, Debes J, Beisang D, Rattenbacher B, Vlasova-St Louis I, Wiesner DL, Cameron CE, Bohjanen PR.

Nucleic Acids Res. 2018 Mar 16;46(5):2537-2547. doi: 10.1093/nar/gky061.


Lung epithelium: barrier immunity to inhaled fungi and driver of fungal-associated allergic asthma.

Wiesner DL, Klein BS.

Curr Opin Microbiol. 2017 Dec;40:8-13. doi: 10.1016/j.mib.2017.10.007. Epub 2017 Oct 27. Review.


The balance between immunity and inflammation.

Wiesner DL, Klein BS.

Science. 2017 Sep 8;357(6355):973-974. doi: 10.1126/science.aao3086. No abstract available.


Different Lymphocyte Populations Direct Dichotomous Eosinophil or Neutrophil Responses to Pulmonary Cryptococcus Infection.

Wiesner DL, Smith KD, Kashem SW, Bohjanen PR, Nielsen K.

J Immunol. 2017 Feb 15;198(4):1627-1637. doi: 10.4049/jimmunol.1600821. Epub 2017 Jan 9.


MyD88 Shapes Vaccine Immunity by Extrinsically Regulating Survival of CD4+ T Cells during the Contraction Phase.

Wang H, Li M, Hung CY, Sinha M, Lee LM, Wiesner DL, LeBert V, Lerksuthirat T, Galles K, Suresh M, DeFranco AL, Lowell CA, Klein BS, Wüthrich M.

PLoS Pathog. 2016 Aug 19;12(8):e1005787. doi: 10.1371/journal.ppat.1005787. eCollection 2016 Aug.


Intracellular Action of a Secreted Peptide Required for Fungal Virulence.

Homer CM, Summers DK, Goranov AI, Clarke SC, Wiesner DL, Diedrich JK, Moresco JJ, Toffaletti D, Upadhya R, Caradonna I, Petnic S, Pessino V, Cuomo CA, Lodge JK, Perfect J, Yates JR 3rd, Nielsen K, Craik CS, Madhani HD.

Cell Host Microbe. 2016 Jun 8;19(6):849-64. doi: 10.1016/j.chom.2016.05.001. Epub 2016 May 19.


Erratum for Rattenbacher et al., Analysis of CUGBP1 Targets Identifies GU-Repeat Sequences That Mediate Rapid mRNA Decay.

Rattenbacher B, Beisang D, Wiesner DL, Jeschke JC, von Hohenberg M, Vlasova-St Louis IA, Bohjanen PR.

Mol Cell Biol. 2016 Feb 1;36(4):660. doi: 10.1128/MCB.01084-15. Print 2016 Feb 15. No abstract available.


Cryptococcus: from environmental saprophyte to global pathogen.

May RC, Stone NR, Wiesner DL, Bicanic T, Nielsen K.

Nat Rev Microbiol. 2016 Feb;14(2):106-17. doi: 10.1038/nrmicro.2015.6. Epub 2015 Dec 21. Review.


Regulatory T Cell Induction and Retention in the Lungs Drives Suppression of Detrimental Type 2 Th Cells During Pulmonary Cryptococcal Infection.

Wiesner DL, Smith KD, Kotov DI, Nielsen JN, Bohjanen PR, Nielsen K.

J Immunol. 2016 Jan 1;196(1):365-74. doi: 10.4049/jimmunol.1501871. Epub 2015 Nov 20.


Chitin recognition via chitotriosidase promotes pathologic type-2 helper T cell responses to cryptococcal infection.

Wiesner DL, Specht CA, Lee CK, Smith KD, Mukaremera L, Lee ST, Lee CG, Elias JA, Nielsen JN, Boulware DR, Bohjanen PR, Jenkins MK, Levitz SM, Nielsen K.

PLoS Pathog. 2015 Mar 12;11(3):e1004701. doi: 10.1371/journal.ppat.1004701. eCollection 2015 Mar.


T cell receptor cross-reactivity between similar foreign and self peptides influences naive cell population size and autoimmunity.

Nelson RW, Beisang D, Tubo NJ, Dileepan T, Wiesner DL, Nielsen K, Wüthrich M, Klein BS, Kotov DI, Spanier JA, Fife BT, Moon JJ, Jenkins MK.

Immunity. 2015 Jan 20;42(1):95-107. Erratum in: Immunity. 2015 Jun 16;42(6):1212-3.


Cryptococcal genotype influences immunologic response and human clinical outcome after meningitis.

Wiesner DL, Moskalenko O, Corcoran JM, McDonald T, Rolfes MA, Meya DB, Kajumbula H, Kambugu A, Bohjanen PR, Knight JF, Boulware DR, Nielsen K.

MBio. 2012 Sep 25;3(5). pii: e00196-12. doi: 10.1128/mBio.00196-12. Print 2012.


Titan cell production enhances the virulence of Cryptococcus neoformans.

Crabtree JN, Okagaki LH, Wiesner DL, Strain AK, Nielsen JN, Nielsen K.

Infect Immun. 2012 Nov;80(11):3776-85. doi: 10.1128/IAI.00507-12. Epub 2012 Aug 13.



McDonald T, Wiesner DL, Nielsen K.

Curr Biol. 2012 Jul 24;22(14):R554-5. doi: 10.1016/j.cub.2012.05.040. No abstract available.


Clinical features and serum biomarkers in HIV immune reconstitution inflammatory syndrome after cryptococcal meningitis: a prospective cohort study.

Boulware DR, Meya DB, Bergemann TL, Wiesner DL, Rhein J, Musubire A, Lee SJ, Kambugu A, Janoff EN, Bohjanen PR.

PLoS Med. 2010 Dec 21;7(12):e1000384. doi: 10.1371/journal.pmed.1000384.


Paucity of initial cerebrospinal fluid inflammation in cryptococcal meningitis is associated with subsequent immune reconstitution inflammatory syndrome.

Boulware DR, Bonham SC, Meya DB, Wiesner DL, Park GS, Kambugu A, Janoff EN, Bohjanen PR.

J Infect Dis. 2010 Sep 15;202(6):962-70. doi: 10.1086/655785.


Analysis of CUGBP1 targets identifies GU-repeat sequences that mediate rapid mRNA decay.

Rattenbacher B, Beisang D, Wiesner DL, Jeschke JC, von Hohenberg M, St Louis-Vlasova IA, Bohjanen PR.

Mol Cell Biol. 2010 Aug;30(16):3970-80. doi: 10.1128/MCB.00624-10. Epub 2010 Jun 14. Erratum in: Mol Cell Biol. 2016 Feb 15;36(4):660.

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