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Items: 1 to 50 of 165

1.

Prominent T-Cell Responses against the Acetylcholine Receptor ε Subunit in Myasthenia Gravis.

Neuhaus O, Wiesmüller KH, Hartung HP, Wiendl H.

Neurol Res Int. 2019 Mar 3;2019:1969068. doi: 10.1155/2019/1969068. eCollection 2019.

2.

The N-terminal peptide moiety of the Mycobacterium tuberculosis 19 kDa lipoprotein harbors RP105-agonistic properties.

Schultz TE, Wiesmüller KH, Lucas M, Dobos KM, Baxter AG, Blumenthal A.

J Leukoc Biol. 2018 Feb;103(2):311-319. doi: 10.1002/JLB.2MA0517-190RR. Epub 2018 Jan 9.

PMID:
29345364
3.

NANOCI-Nanotechnology Based Cochlear Implant With Gapless Interface to Auditory Neurons.

Senn P, Roccio M, Hahnewald S, Frick C, Kwiatkowska M, Ishikawa M, Bako P, Li H, Edin F, Liu W, Rask-Andersen H, Pyykkö I, Zou J, Mannerström M, Keppner H, Homsy A, Laux E, Llera M, Lellouche JP, Ostrovsky S, Banin E, Gedanken A, Perkas N, Wank U, Wiesmüller KH, Mistrík P, Benav H, Garnham C, Jolly C, Gander F, Ulrich P, Müller M, Löwenheim H.

Otol Neurotol. 2017 Sep;38(8):e224-e231. doi: 10.1097/MAO.0000000000001439. Review.

4.

Biofunctionalized peptide-based hydrogels provide permissive scaffolds to attract neurite outgrowth from spiral ganglion neurons.

Frick C, Müller M, Wank U, Tropitzsch A, Kramer B, Senn P, Rask-Andersen H, Wiesmüller KH, Löwenheim H.

Colloids Surf B Biointerfaces. 2017 Jan 1;149:105-114. doi: 10.1016/j.colsurfb.2016.10.003. Epub 2016 Oct 4.

PMID:
27736723
5.

Lipoproteins/peptides are sepsis-inducing toxins from bacteria that can be neutralized by synthetic anti-endotoxin peptides.

Martinez de Tejada G, Heinbockel L, Ferrer-Espada R, Heine H, Alexander C, Bárcena-Varela S, Goldmann T, Correa W, Wiesmüller KH, Gisch N, Sánchez-Gómez S, Fukuoka S, Schürholz T, Gutsmann T, Brandenburg K.

Sci Rep. 2015 Sep 22;5:14292. doi: 10.1038/srep14292.

6.

An Antifungal Benzimidazole Derivative Inhibits Ergosterol Biosynthesis and Reveals Novel Sterols.

Keller P, Müller C, Engelhardt I, Hiller E, Lemuth K, Eickhoff H, Wiesmüller KH, Burger-Kentischer A, Bracher F, Rupp S.

Antimicrob Agents Chemother. 2015 Oct;59(10):6296-307. doi: 10.1128/AAC.00640-15. Epub 2015 Jul 27.

7.

Modular multiantigen T cell epitope-enriched DNA vaccine against human leishmaniasis.

Das S, Freier A, Boussoffara T, Das S, Oswald D, Losch FO, Selka M, Sacerdoti-Sierra N, Schönian G, Wiesmüller KH, Seifert K, Schroff M, Juhls C, Jaffe CL, Roy S, Das P, Louzir H, Croft SL, Modabber F, Walden P.

Sci Transl Med. 2014 Apr 30;6(234):234ra56. doi: 10.1126/scitranslmed.3008222.

8.

NSP4 is stored in azurophil granules and released by activated neutrophils as active endoprotease with restricted specificity.

Perera NC, Wiesmüller KH, Larsen MT, Schacher B, Eickholz P, Borregaard N, Jenne DE.

J Immunol. 2013 Sep 1;191(5):2700-7. doi: 10.4049/jimmunol.1301293. Epub 2013 Jul 31.

9.

A novel synthetic lipopeptide is allergy-protective by the induction of LPS-tolerance.

Stiehm M, Peters K, Wiesmüller KH, Bufe A, Peters M.

Clin Exp Allergy. 2013 Jul;43(7):785-97. doi: 10.1111/cea.12116.

PMID:
23786285
10.

Direct activation of human dendritic cells by particle-bound but not soluble MHC class II ligand.

Baleeiro RB, Wiesmüller KH, Dähne L, Lademann J, Barbuto JA, Walden P.

PLoS One. 2013 May 2;8(5):e63039. doi: 10.1371/journal.pone.0063039. Print 2013.

11.

Topical vaccination with functionalized particles targeting dendritic cells.

Baleeiro RB, Wiesmüller KH, Reiter Y, Baude B, Dähne L, Patzelt A, Lademann J, Barbuto JA, Walden P.

J Invest Dermatol. 2013 Aug;133(8):1933-41. doi: 10.1038/jid.2013.79. Epub 2013 Feb 20.

12.

Lipid-labeling facilitates a novel magnetic isolation procedure to characterize pathogen-containing phagosomes.

Steinhäuser C, Heigl U, Tchikov V, Schwarz J, Gutsmann T, Seeger K, Brandenburg J, Fritsch J, Schroeder J, Wiesmüller KH, Rosenkrands I, Walther P, Pott J, Krause E, Ehlers S, Schneider-Brachert W, Schütze S, Reiling N.

Traffic. 2013 Mar;14(3):321-36. doi: 10.1111/tra.12031. Epub 2012 Dec 28.

13.

Early neutralizing IgG response to Chikungunya virus in infected patients targets a dominant linear epitope on the E2 glycoprotein.

Kam YW, Lum FM, Teo TH, Lee WW, Simarmata D, Harjanto S, Chua CL, Chan YF, Wee JK, Chow A, Lin RT, Leo YS, Le Grand R, Sam IC, Tong JC, Roques P, Wiesmüller KH, Rénia L, Rötzschke O, Ng LF.

EMBO Mol Med. 2012 Apr;4(4):330-43. doi: 10.1002/emmm.201200213. Epub 2012 Mar 5.

14.

A screening assay based on host-pathogen interaction models identifies a set of novel antifungal benzimidazole derivatives.

Burger-Kentischer A, Finkelmeier D, Keller P, Bauer J, Eickhoff H, Kleymann G, Abu Rayyan W, Singh A, Schröppel K, Lemuth K, Wiesmüller KH, Rupp S.

Antimicrob Agents Chemother. 2011 Oct;55(10):4789-801. doi: 10.1128/AAC.01657-10. Epub 2011 Jul 11.

15.

High-throughput-screening-based identification and structure-activity relationship characterization defined (S)-2-(1-aminoisobutyl)-1-(3-chlorobenzyl)benzimidazole as a highly antimycotic agent nontoxic to cell lines.

Bauer J, Kinast S, Burger-Kentischer A, Finkelmeier D, Kleymann G, Rayyan WA, Schröppel K, Singh A, Jung G, Wiesmüller KH, Rupp S, Eickhoff H.

J Med Chem. 2011 Oct 13;54(19):6993-7. doi: 10.1021/jm200571e. Epub 2011 Aug 31.

PMID:
21711055
16.

Characterization of structural features controlling the receptiveness of empty class II MHC molecules.

Rupp B, Günther S, Makhmoor T, Schlundt A, Dickhaut K, Gupta S, Choudhary I, Wiesmüller KH, Jung G, Freund C, Falk K, Rötzschke O, Kühne R.

PLoS One. 2011 Apr 14;6(4):e18662. doi: 10.1371/journal.pone.0018662.

17.

CyLoP-1: a novel cysteine-rich cell-penetrating peptide for cytosolic delivery of cargoes.

Jha D, Mishra R, Gottschalk S, Wiesmüller KH, Ugurbil K, Maier ME, Engelmann J.

Bioconjug Chem. 2011 Mar 16;22(3):319-28. doi: 10.1021/bc100045s. Epub 2011 Feb 14.

PMID:
21319732
18.

Conformation of peptides bound to the transporter associated with antigen processing (TAP).

Herget M, Baldauf C, Schölz C, Parcej D, Wiesmüller KH, Tampé R, Abele R, Bordignon E.

Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1349-54. doi: 10.1073/pnas.1012355108. Epub 2011 Jan 4.

19.

Influence of the vehicle on the penetration of particles into hair follicles.

Patzelt A, Richter H, Dähne L, Walden P, Wiesmüller KH, Wank U, Sterry W, Lademann J.

Pharmaceutics. 2011 Jun 14;3(2):307-14. doi: 10.3390/pharmaceutics3020307.

20.

Design, Synthesis, and in Vitro Evaluation of Novel Aminomethyl-pyridines as DPP-4 Inhibitors.

Kaczanowska K, Wiesmüller KH, Schaffner AP.

ACS Med Chem Lett. 2010 Oct 5;1(9):530-5. doi: 10.1021/ml100200c. eCollection 2010 Dec 9.

21.

Bidirectional binding of invariant chain peptides to an MHC class II molecule.

Günther S, Schlundt A, Sticht J, Roske Y, Heinemann U, Wiesmüller KH, Jung G, Falk K, Rötzschke O, Freund C.

Proc Natl Acad Sci U S A. 2010 Dec 21;107(51):22219-24. doi: 10.1073/pnas.1014708107. Epub 2010 Nov 29.

22.

The synthetic bacterial lipopeptide Pam3CSK4 modulates respiratory syncytial virus infection independent of TLR activation.

Nguyen DT, de Witte L, Ludlow M, Yüksel S, Wiesmüller KH, Geijtenbeek TB, Osterhaus AD, de Swart RL.

PLoS Pathog. 2010 Aug 19;6(8):e1001049. doi: 10.1371/journal.ppat.1001049.

23.

Peptide microarrays for the profiling of cytotoxic T-lymphocyte activity using minimum numbers of cells.

Hoff A, Bagû AC, André T, Roth G, Wiesmüller KH, Gückel B, Brock R.

Cancer Immunol Immunother. 2010 Sep;59(9):1379-87. doi: 10.1007/s00262-010-0867-4. Epub 2010 May 29.

24.

MHC I stabilizing potential of computer-designed octapeptides.

Wisniewska JM, Jäger N, Freier A, Losch FO, Wiesmüller KH, Walden P, Wrede P, Schneider G, Hiss JA.

J Biomed Biotechnol. 2010;2010:396847. doi: 10.1155/2010/396847. Epub 2010 May 25.

25.

A new cell-based innate immune receptor assay for the examination of receptor activity, ligand specificity, signalling pathways and the detection of pyrogens.

Burger-Kentischer A, Abele IS, Finkelmeier D, Wiesmüller KH, Rupp S.

J Immunol Methods. 2010 Jun 30;358(1-2):93-103. doi: 10.1016/j.jim.2010.03.020. Epub 2010 Apr 10.

PMID:
20385141
26.

In situ assembly of macromolecular complexes triggered by light.

Grunwald C, Schulze K, Reichel A, Weiss VU, Blaas D, Piehler J, Wiesmüller KH, Tampé R.

Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6146-51. doi: 10.1073/pnas.0912617107. Epub 2010 Mar 3.

27.

Identification of full length bovine TLR1 and functional characterization of lipopeptide recognition by bovine TLR2/1 heterodimer.

Farhat K, Riekenberg S, Jung G, Wiesmüller KH, Jungi TW, Ulmer AJ.

Vet Res. 2010 May-Jun;41(3):34. doi: 10.1051/vetres/2010006. Epub 2010 Jan 26.

28.

Influence of serum on the immune recognition of a synthetic lipopeptide mimetic of the 19-kDa lipoprotein from Mycobacterium tuberculosis.

Schromm AB, Reiling N, Howe J, Wiesmüller KH, Roessle M, Brandenburg K.

Innate Immun. 2010 Aug;16(4):213-25. doi: 10.1177/1753425909339232. Epub 2009 Aug 26.

PMID:
19710101
29.

Selectivity of competitive multivalent interactions at interfaces.

André T, Reichel A, Wiesmüller KH, Tampé R, Piehler J, Brock R.

Chembiochem. 2009 Jul 20;10(11):1878-87. doi: 10.1002/cbic.200900001.

PMID:
19565593
30.

Diffusion-driven device for a high-resolution dose-response profiling of combination chemotherapy.

Ganser A, Roth G, van Galen JC, Hilderink J, Wammes JJ, Müller I, van Leeuwen FN, Wiesmüller KH, Brock R.

Anal Chem. 2009 Jul 1;81(13):5233-40. doi: 10.1021/ac900415s.

PMID:
19476343
31.

Identification of major histocompatibility complex restriction and anchor residues of foot-and-mouth disease virus-derived bovine T-cell epitopes.

Gerner W, Hammer SE, Wiesmüller KH, Saalmüller A.

J Virol. 2009 May;83(9):4039-50. doi: 10.1128/JVI.01534-08. Epub 2009 Feb 11.

32.

Regulators of G-protein signalling are modulated by bacterial lipopeptides and lipopolysaccharide.

Riekenberg S, Farhat K, Debarry J, Heine H, Jung G, Wiesmüller KH, Ulmer AJ.

FEBS J. 2009 Feb;276(3):649-59. doi: 10.1111/j.1742-4658.2008.06813.x. Epub 2008 Dec 12.

33.

HPMA as a scaffold for the modular assembly of functional peptide polymers by native chemical ligation.

Ruttekolk IR, Duchardt F, Fischer R, Wiesmüller KH, Rademann J, Brock R.

Bioconjug Chem. 2008 Oct;19(10):2081-7. doi: 10.1021/bc800222e. Epub 2008 Sep 9.

PMID:
18778092
34.

Complementary strategies to elucidate T helper cell epitopes in myasthenia gravis.

Jung C, Stoeckle C, Wiesmüller KH, Laub R, Emmrich F, Jung G, Melms A.

J Neuroimmunol. 2008 Sep 15;201-202:41-9. doi: 10.1016/j.jneuroim.2008.06.010. Epub 2008 Jul 22.

PMID:
18649950
35.

Anchor side chains of short peptide fragments trigger ligand-exchange of class II MHC molecules.

Gupta S, Höpner S, Rupp B, Günther S, Dickhaut K, Agarwal N, Cardoso MC, Kühne R, Wiesmüller KH, Jung G, Falk K, Rötzschke O.

PLoS One. 2008 Mar 19;3(3):e1814. doi: 10.1371/journal.pone.0001814.

36.

Glutaminyl cyclase activity is a characteristic feature of human cerebrospinal fluid.

Gontsarova A, Kaufmann E, Tumani H, Dressel A, Mandel F, Wiesmüller KH, Kunert-Keil C, Brinkmeier H.

Clin Chim Acta. 2008 Mar;389(1-2):152-9. doi: 10.1016/j.cca.2007.12.010. Epub 2007 Dec 17.

PMID:
18187042
37.

Heterodimerization of TLR2 with TLR1 or TLR6 expands the ligand spectrum but does not lead to differential signaling.

Farhat K, Riekenberg S, Heine H, Debarry J, Lang R, Mages J, Buwitt-Beckmann U, Röschmann K, Jung G, Wiesmüller KH, Ulmer AJ.

J Leukoc Biol. 2008 Mar;83(3):692-701. Epub 2007 Dec 3.

PMID:
18056480
38.

Characterization of the encephalitogenic immune response in a model of multiple sclerosis.

de Graaf KL, Barth S, Herrmann MM, Storch MK, Wiesmüller KH, Weissert R.

Eur J Immunol. 2008 Jan;38(1):299-308.

39.

The activity of lipopeptide TLR2 agonists critically depends on the presence of solubilizers.

Voss S, Ulmer AJ, Jung G, Wiesmüller KH, Brock R.

Eur J Immunol. 2007 Dec;37(12):3489-98.

40.

Identification of a novel foot-and-mouth disease virus specific T-cell epitope with immunodominant characteristics in cattle with MHC serotype A31.

Gerner W, Carr BV, Wiesmüller KH, Pfaff E, Saalmüller A, Charleston B.

Vet Res. 2007 Jul-Aug;38(4):565-72. Epub 2007 May 30.

41.

Biosynthesis of Wdr16, a marker protein for kinocilia-bearing cells, starts at the time of kinocilia formation in rat, and wdr16 gene knockdown causes hydrocephalus in zebrafish.

Hirschner W, Pogoda HM, Kramer C, Thiess U, Hamprecht B, Wiesmüller KH, Lautner M, Verleysdonk S.

J Neurochem. 2007 Apr;101(1):274-88.

42.

Synthesis and cellular uptake of a MR contrast agent coupled to an antisense peptide nucleic acid--cell- penetrating peptide conjugate.

Su W, Mishra R, Pfeuffer J, Wiesmüller KH, Ugurbil K, Engelmann J.

Contrast Media Mol Imaging. 2007 Jan-Feb;2(1):42-9.

PMID:
17318918
43.

Physicochemical and biological analysis of synthetic bacterial lipopeptides: validity of the concept of endotoxic conformation.

Schromm AB, Howe J, Ulmer AJ, Wiesmüller KH, Seyberth T, Jung G, Rössle M, Koch MH, Gutsmann T, Brandenburg K.

J Biol Chem. 2007 Apr 13;282(15):11030-7. Epub 2007 Feb 17.

44.

Mimotope vaccines for cancer immunotherapy.

Sharav T, Wiesmüller KH, Walden P.

Vaccine. 2007 Apr 20;25(16):3032-7. Epub 2007 Jan 22. Review.

PMID:
17276556
45.

A fluorescence-based synthetic LPS sensor.

Voss S, Fischer R, Jung G, Wiesmüller KH, Brock R.

J Am Chem Soc. 2007 Jan 24;129(3):554-61.

PMID:
17227018
46.

Ubiquitin binds to a short peptide segment of hydrolase UCH-L3: a study by FCS, RIfS, ITC and NMR.

Roth G, Freund S, Möhrle B, Wöllner K, Brünjes J, Gauglitz G, Wiesmüller KH, Jung G.

Chembiochem. 2007 Feb 12;8(3):323-31.

PMID:
17211910
47.

Identification of novel foot-and-mouth disease virus specific T-cell epitopes in c/c and d/d haplotype miniature swine.

Gerner W, Denyer MS, Takamatsu HH, Wileman TE, Wiesmüller KH, Pfaff E, Saalmüller A.

Virus Res. 2006 Nov;121(2):223-8. Epub 2006 Aug 28.

PMID:
16934904
48.

Lipolanthionine peptides act as inhibitors of TLR2-mediated IL-8 secretion. Synthesis and structure-activity relationships.

Seyberth T, Voss S, Brock R, Wiesmüller KH, Jung G.

J Med Chem. 2006 Mar 9;49(5):1754-65.

PMID:
16509590
49.

TLR1- and TLR6-independent recognition of bacterial lipopeptides.

Buwitt-Beckmann U, Heine H, Wiesmüller KH, Jung G, Brock R, Akira S, Ulmer AJ.

J Biol Chem. 2006 Apr 7;281(14):9049-57. Epub 2006 Feb 2.

50.

A CD14 domain with lipopolysaccharide-binding and -neutralizing activity.

Voss S, Welte S, Fotin-Mleczek M, Fischer R, Ulmer AJ, Jung G, Wiesmüller KH, Brock R.

Chembiochem. 2006 Feb;7(2):275-86.

PMID:
16444757

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