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Items: 1 to 50 of 158


Optimal Decoding of Cellular Identities in a Genetic Network.

Petkova MD, Tkačik G, Bialek W, Wieschaus EF, Gregor T.

Cell. 2019 Feb 7;176(4):844-855.e15. doi: 10.1016/j.cell.2019.01.007. Epub 2019 Jan 31.


The Science of Living Matter for Tomorrow.

Bauer G, Fakhri N, Kicheva A, Kondev J, Kruse K, Noji H, Riveline D, Saunders TE, Thattai M, Wieschaus E.

Cell Syst. 2018 Apr 25;6(4):400-402. doi: 10.1016/j.cels.2018.04.003. No abstract available.


Global morphogenetic flow is accurately predicted by the spatial distribution of myosin motors.

Streichan SJ, Lefebvre MF, Noll N, Wieschaus EF, Shraiman BI.

Elife. 2018 Feb 9;7. pii: e27454. doi: 10.7554/eLife.27454.


Concentration dependent chromatin states induced by the bicoid morphogen gradient.

Hannon CE, Blythe SA, Wieschaus EF.

Elife. 2017 Sep 11;6. pii: e28275. doi: 10.7554/eLife.28275.


Independent active and thermodynamic processes govern the nucleolus assembly in vivo.

Falahati H, Wieschaus E.

Proc Natl Acad Sci U S A. 2017 Feb 7;114(6):1335-1340. doi: 10.1073/pnas.1615395114. Epub 2017 Jan 23. Erratum in: Proc Natl Acad Sci U S A. 2017 Apr 25;114(17 ):E3585.


Measurement of cortical elasticity in Drosophila melanogaster embryos using ferrofluids.

Doubrovinski K, Swan M, Polyakov O, Wieschaus EF.

Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):1051-1056. doi: 10.1073/pnas.1616659114. Epub 2017 Jan 17.


Polarity protein Par3/Bazooka follows myosin-dependent junction repositioning.

Weng M, Wieschaus E.

Dev Biol. 2017 Feb 15;422(2):125-134. doi: 10.1016/j.ydbio.2017.01.001. Epub 2017 Jan 5.


Establishment and maintenance of heritable chromatin structure during early Drosophila embryogenesis.

Blythe SA, Wieschaus EF.

Elife. 2016 Nov 23;5. pii: e20148. doi: 10.7554/eLife.20148.


Transcriptional Timers Regulating Mitosis in Early Drosophila Embryos.

Momen-Roknabadi A, Di Talia S, Wieschaus E.

Cell Rep. 2016 Sep 13;16(11):2793-2801. doi: 10.1016/j.celrep.2016.08.034.


The Heidelberg Screen for Pattern Mutants of Drosophila: A Personal Account.

Wieschaus E, Nüsslein-Volhard C.

Annu Rev Cell Dev Biol. 2016 Oct 6;32:1-46. Epub 2016 Aug 3. Review.


Flow-dependent myosin recruitment during Drosophila cellularization requires zygotic dunk activity.

He B, Martin A, Wieschaus E.

Development. 2016 Jul 1;143(13):2417-30. doi: 10.1242/dev.131334. Epub 2016 May 25.


Positional Information and Cell Fate Determination in the Early Drosophila Embryo.

Wieschaus E.

Curr Top Dev Biol. 2016;117:567-79. doi: 10.1016/bs.ctdb.2015.11.020. Epub 2016 Jan 7. Review.


Corrigendum: Independent and coordinate trafficking of single Drosophila germ plasm mRNAs.

Little SC, Sinsimer KS, Lee JJ, Wieschaus EF, Gavis ER.

Nat Cell Biol. 2016 Mar;18(3):347. doi: 10.1038/ncb3317. No abstract available.


Nucleation by rRNA Dictates the Precision of Nucleolus Assembly.

Falahati H, Pelham-Webb B, Blythe S, Wieschaus E.

Curr Biol. 2016 Feb 8;26(3):277-85. doi: 10.1016/j.cub.2015.11.065. Epub 2016 Jan 14.


Myosin-dependent remodeling of adherens junctions protects junctions from Snail-dependent disassembly.

Weng M, Wieschaus E.

J Cell Biol. 2016 Jan 18;212(2):219-29. doi: 10.1083/jcb.201508056. Epub 2016 Jan 11.


Coordinating Cell Cycle Remodeling with Transcriptional Activation at the Drosophila MBT.

Blythe SA, Wieschaus EF.

Curr Top Dev Biol. 2015;113:113-48. doi: 10.1016/bs.ctdb.2015.06.002. Epub 2015 Jul 29. Review.


Diversity of epithelial morphogenesis during eggshell formation in drosophilids.

Osterfield M, Schüpbach T, Wieschaus E, Shvartsman SY.

Development. 2015 Jun 1;142(11):1971-7. doi: 10.1242/dev.119404. Epub 2015 May 7.


Independent and coordinate trafficking of single Drosophila germ plasm mRNAs.

Little SC, Sinsimer KS, Lee JJ, Wieschaus EF, Gavis ER.

Nat Cell Biol. 2015 May;17(5):558-68. doi: 10.1038/ncb3143. Epub 2015 Apr 6. Erratum in: Nat Cell Biol. 2016 Mar;18(3):347.


Zygotic genome activation triggers the DNA replication checkpoint at the midblastula transition.

Blythe SA, Wieschaus EF.

Cell. 2015 Mar 12;160(6):1169-81. doi: 10.1016/j.cell.2015.01.050. Epub 2015 Mar 5.


Walter Gehring (1939–2014).

Wieschaus E, Nüsslein-Volhard C.

Curr Biol. 2014 Jul 21;24(14):R632-4. No abstract available.


Passive mechanical forces control cell-shape change during Drosophila ventral furrow formation.

Polyakov O, He B, Swan M, Shaevitz JW, Kaschube M, Wieschaus E.

Biophys J. 2014 Aug 19;107(4):998-1010. doi: 10.1016/j.bpj.2014.07.013.


Simple biochemical pathways far from steady state can provide switchlike and integrated responses.

Di Talia S, Wieschaus EF.

Biophys J. 2014 Aug 5;107(3):L1-L4. doi: 10.1016/j.bpj.2014.06.018.


Quantitative 4D analyses of epithelial folding during Drosophila gastrulation.

Khan Z, Wang YC, Wieschaus EF, Kaschube M.

Development. 2014 Jul;141(14):2895-900. doi: 10.1242/dev.107730. Epub 2014 Jun 19.


Apical constriction drives tissue-scale hydrodynamic flow to mediate cell elongation.

He B, Doubrovinski K, Polyakov O, Wieschaus E.

Nature. 2014 Apr 17;508(7496):392-6. doi: 10.1038/nature13070. Epub 2014 Mar 2.


Positional information, in bits.

Dubuis JO, Tkacik G, Wieschaus EF, Gregor T, Bialek W.

Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16301-8. doi: 10.1073/pnas.1315642110. Epub 2013 Oct 2.


Distinct Rap1 activity states control the extent of epithelial invagination via α-catenin.

Wang YC, Khan Z, Wieschaus EF.

Dev Cell. 2013 May 13;25(3):299-309. doi: 10.1016/j.devcel.2013.04.002. Epub 2013 Apr 25.


Three-dimensional epithelial morphogenesis in the developing Drosophila egg.

Osterfield M, Du X, Schüpbach T, Wieschaus E, Shvartsman SY.

Dev Cell. 2013 Feb 25;24(4):400-10. doi: 10.1016/j.devcel.2013.01.017.


Posttranslational control of Cdc25 degradation terminates Drosophila's early cell-cycle program.

Di Talia S, She R, Blythe SA, Lu X, Zhang QF, Wieschaus EF.

Curr Biol. 2013 Jan 21;23(2):127-32. doi: 10.1016/j.cub.2012.11.029. Epub 2013 Jan 3.


Volume conservation principle involved in cell lengthening and nucleus movement during tissue morphogenesis.

Gelbart MA, He B, Martin AC, Thiberge SY, Wieschaus EF, Kaschube M.

Proc Natl Acad Sci U S A. 2012 Nov 20;109(47):19298-303. doi: 10.1073/pnas.1205258109. Epub 2012 Nov 7.


Torso RTK controls Capicua degradation by changing its subcellular localization.

Grimm O, Sanchez Zini V, Kim Y, Casanova J, Shvartsman SY, Wieschaus E.

Development. 2012 Nov;139(21):3962-8. doi: 10.1242/dev.084327.


The synthesis-diffusion-degradation model explains Bicoid gradient formation in unfertilized eggs.

Drocco JA, Wieschaus EF, Tank DW.

Phys Biol. 2012 Oct;9(5):055004. doi: 10.1088/1478-3975/9/5/055004. Epub 2012 Sep 25.


Mapping the pericentric heterochromatin by comparative genomic hybridization analysis and chromosome deletions in Drosophila melanogaster.

He B, Caudy A, Parsons L, Rosebrock A, Pane A, Raj S, Wieschaus E.

Genome Res. 2012 Dec;22(12):2507-19. doi: 10.1101/gr.137406.112. Epub 2012 Jun 28.


Short-term integration of Cdc25 dynamics controls mitotic entry during Drosophila gastrulation.

Di Talia S, Wieschaus EF.

Dev Cell. 2012 Apr 17;22(4):763-74. doi: 10.1016/j.devcel.2012.01.019. Epub 2012 Apr 5.


Differential positioning of adherens junctions is associated with initiation of epithelial folding.

Wang YC, Khan Z, Kaschube M, Wieschaus EF.

Nature. 2012 Mar 28;484(7394):390-3. doi: 10.1038/nature10938.


Introducing WIREs Developmental Biology.

Gerhart JC, Martin GR, Wieschaus EF.

Wiley Interdiscip Rev Dev Biol. 2012 Jan-Feb;1(1):1-2. doi: 10.1002/wdev.13. Epub 2011 Dec 5. No abstract available.


Measurement and perturbation of morphogen lifetime: effects on gradient shape.

Drocco JA, Grimm O, Tank DW, Wieschaus E.

Biophys J. 2011 Oct 19;101(8):1807-15. doi: 10.1016/j.bpj.2011.07.025.


Shifting patterns: merging molecules, morphogens, motility, and methodology.

Little SC, Wieschaus EF.

Dev Cell. 2011 Jul 19;21(1):2-4. doi: 10.1016/j.devcel.2011.06.003.


The formation of the Bicoid morphogen gradient requires protein movement from anteriorly localized mRNA.

Little SC, Tkačik G, Kneeland TB, Wieschaus EF, Gregor T.

PLoS Biol. 2011 Mar;9(3):e1000596. doi: 10.1371/journal.pbio.1000596. Epub 2011 Mar 1.


The Bicoid gradient is shaped independently of nuclei.

Grimm O, Wieschaus E.

Development. 2010 Sep 1;137(17):2857-62. doi: 10.1242/dev.052589.


Cell cycle regulation via inter-nuclear communication during the early embryonic development of Drosophila melanogaster.

Lu X, Drocco J, Wieschaus EF.

Cell Cycle. 2010 Jul 15;9(14):2908-10. Epub 2010 Jul 11. No abstract available.


Modelling the Bicoid gradient.

Grimm O, Coppey M, Wieschaus E.

Development. 2010 Jul;137(14):2253-64. doi: 10.1242/dev.032409. Review.


Integration of contractile forces during tissue invagination.

Martin AC, Gelbart M, Fernandez-Gonzalez R, Kaschube M, Wieschaus EF.

J Cell Biol. 2010 Mar 8;188(5):735-49. doi: 10.1083/jcb.200910099. Epub 2010 Mar 1.


Tensions divide.

Martin AC, Wieschaus EF.

Nat Cell Biol. 2010 Jan;12(1):5-7. doi: 10.1038/ncb0110-5.


Coupling of zygotic transcription to mitotic control at the Drosophila mid-blastula transition.

Lu X, Li JM, Elemento O, Tavazoie S, Wieschaus EF.

Development. 2009 Jun;136(12):2101-10. doi: 10.1242/dev.034421.


Pulsed contractions of an actin-myosin network drive apical constriction.

Martin AC, Kaschube M, Wieschaus EF.

Nature. 2009 Jan 22;457(7228):495-9. doi: 10.1038/nature07522. Epub 2008 Nov 23.


Local actin-dependent endocytosis is zygotically controlled to initiate Drosophila cellularization.

Sokac AM, Wieschaus E.

Dev Cell. 2008 May;14(5):775-86. doi: 10.1016/j.devcel.2008.02.014.


Zygotically controlled F-actin establishes cortical compartments to stabilize furrows during Drosophila cellularization.

Sokac AM, Wieschaus E.

J Cell Sci. 2008 Jun 1;121(11):1815-24. doi: 10.1242/jcs.025171. Epub 2008 May 6.


Shape and function of the Bicoid morphogen gradient in dipteran species with different sized embryos.

Gregor T, McGregor AP, Wieschaus EF.

Dev Biol. 2008 Apr 15;316(2):350-8. doi: 10.1016/j.ydbio.2008.01.039. Epub 2008 Feb 13.


Probing the limits to positional information.

Gregor T, Tank DW, Wieschaus EF, Bialek W.

Cell. 2007 Jul 13;130(1):153-64.


Stability and nuclear dynamics of the bicoid morphogen gradient.

Gregor T, Wieschaus EF, McGregor AP, Bialek W, Tank DW.

Cell. 2007 Jul 13;130(1):141-52.

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