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Items: 1 to 50 of 68

1.

Interferon Gamma-Induced Protein (IP-10) as Potential Biomarker for Cancer-Related-Fatigue: Results from a 6-month Randomized Controlled Trial.

Ter Veer E, Prinsen H, Sprangers MAG, Zwinderman KAH, Bleijenberg G, van der Pouw Kraan TCTM, de Vries IJM, Wierenga EA, van Laarhoven HWM.

Cancer Invest. 2018;36(7):371-377. doi: 10.1080/07357907.2018.1499933. Epub 2018 Sep 6.

PMID:
30188739
2.

Biological pathways, candidate genes, and molecular markers associated with quality-of-life domains: an update.

Sprangers MA, Thong MS, Bartels M, Barsevick A, Ordoñana J, Shi Q, Wang XS, Klepstad P, Wierenga EA, Singh JA, Sloan JA; GeneQol Consortium.

Qual Life Res. 2014 Sep;23(7):1997-2013. doi: 10.1007/s11136-014-0656-1. Epub 2014 Mar 7. Review.

3.

Value of PCA3 to predict biopsy outcome and its potential role in selecting patients for multiparametric MRI.

Leyten GH, Wierenga EA, Sedelaar JP, van Oort IM, Futterer JJ, Barentsz JO, Schalken JA, Mulders PF.

Int J Mol Sci. 2013 May 28;14(6):11347-55. doi: 10.3390/ijms140611347.

4.

Are adults with congenital heart disease at risk for the development of heart failure when feeling depressed? An immunological mechanism.

Schoormans D, Wierenga EA.

Pediatr Cardiol. 2012 Oct;33(7):1233-4. doi: 10.1007/s00246-012-0383-8. Epub 2012 May 26. No abstract available.

PMID:
22639006
5.

The influence of the AA 16 beta 2-adrenoceptor polymorphism on systemic and airway responses in asthma.

van Veen A, Weller FR, Wierenga EA, Jansen HM, Jonkers RE.

Pulm Pharmacol Ther. 2008;21(1):73-8. Epub 2006 Dec 29.

PMID:
17292646
6.

Differentially methylated alleles in a distinct region of the human interleukin-1alpha promoter are associated with allele-specific expression of IL-1alpha in CD4+ T cells.

van Rietschoten JG, Verzijlbergen KF, Gringhuis SI, van der Pouw Kraan TC, Bayley JP, Wierenga EA, Jones PA, Kooter JM, Verweij CL.

Blood. 2006 Oct 1;108(7):2143-9. Epub 2006 Jun 20.

7.

Limited beta2-adrenoceptor haplotypes display different agonist mediated airway responses in asthmatics.

van Veen A, Wierenga EA, Westland R, Weller FR, Hart GA, Jansen HM, Jonkers RE.

Respir Res. 2006 Jan 31;7:19.

8.

Selective probiotic bacteria induce IL-10-producing regulatory T cells in vitro by modulating dendritic cell function through dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin.

Smits HH, Engering A, van der Kleij D, de Jong EC, Schipper K, van Capel TM, Zaat BA, Yazdanbakhsh M, Wierenga EA, van Kooyk Y, Kapsenberg ML.

J Allergy Clin Immunol. 2005 Jun;115(6):1260-7.

PMID:
15940144
9.

Different faces of regulatory DCs in homeostasis and immunity.

Smits HH, de Jong EC, Wierenga EA, Kapsenberg ML.

Trends Immunol. 2005 Mar;26(3):123-9. Review. No abstract available.

PMID:
15745853
10.

Limited impact of multiple 5' single-nucleotide polymorphisms on the transcriptional control of the human beta 2-adrenoceptor gene.

Westland R, van Veen A, Jansen HM, Jonkers RE, Wierenga EA.

Immunogenetics. 2004 Dec;56(9):625-30. Epub 2004 Nov 17.

PMID:
15578262
11.

ICOS expression by activated human Th cells is enhanced by IL-12 and IL-23: increased ICOS expression enhances the effector function of both Th1 and Th2 cells.

Wassink L, Vieira PL, Smits HH, Kingsbury GA, Coyle AJ, Kapsenberg ML, Wierenga EA.

J Immunol. 2004 Aug 1;173(3):1779-86.

12.

A novel polymorphic GATA site in the human IL-12Rbeta2 promoter region affects transcriptional activity.

van Rietschoten JG, Westland R, van den Bogaard R, Nieste-Otter MA, van Veen A, Jonkers RE, van der Pouw Kraan TC, den Hartog MT, Wierenga EA.

Tissue Antigens. 2004 Jun;63(6):538-46.

PMID:
15140029
13.

Commensal Gram-negative bacteria prime human dendritic cells for enhanced IL-23 and IL-27 expression and enhanced Th1 development.

Smits HH, van Beelen AJ, Hessle C, Westland R, de Jong E, Soeteman E, Wold A, Wierenga EA, Kapsenberg ML.

Eur J Immunol. 2004 May;34(5):1371-80.

14.

ICOS-mediated signaling regulates cytokine production by human T cells and provides a unique signal to selectively control the clonal expansion of Th2 helper cells.

Vieira PL, Wassink L, Smith LM, Nam S, Kingsbury GA, Gutierrez-Ramos JC, Coyle AJ, Kapsenberg ML, Wierenga EA.

Eur J Immunol. 2004 May;34(5):1282-90.

15.

Monocyte-derived dendritic cells exposed to Der p 1 allergen enhance the recruitment of Th2 cells: major involvement of the chemokines TARC/CCL17 and MDC/CCL22.

Hammad H, Smits HH, Ratajczak C, Nithiananthan A, Wierenga EA, Stewart GA, Jacquet A, Tonnel AB, Pestel J.

Eur Cytokine Netw. 2003 Oct-Dec;14(4):219-28. Erratum in: Eur Cytokine Netw. 2004 Jan-Mar;15(1):73.

16.

Allele-specific expression of the IL-1 alpha gene in human CD4+ T cell clones.

Bayley JP, van Rietschoten JG, Bakker AM, van Baarsen L, Kaijzel EL, Wierenga EA, van der Pouw Kraan TC, Huizinga TW, Verweij CL.

J Immunol. 2003 Sep 1;171(5):2349-53.

17.

Analysis of allelic expression patterns of IL-2, IL-3, IL-4, and IL-13 in human CD4+ T cell clones.

Bayley JP, Bakker AM, Kaijzel EL, Wierenga EA, van der Pouw-Kraan TC, Huizinga TW, Verweij CL.

Eur J Immunol. 2003 Aug;33(8):2142-8.

18.

A comparison of salmeterol and formoterol in attenuating airway responses to short-acting beta2-agonists.

van Veen A, Weller FR, Wierenga EA, Jansen HM, Jonkers RE.

Pulm Pharmacol Ther. 2003;16(3):153-61.

PMID:
12749831
19.

Glatiramer acetate (copolymer-1, copaxone) promotes Th2 cell development and increased IL-10 production through modulation of dendritic cells.

Vieira PL, Heystek HC, Wormmeester J, Wierenga EA, Kapsenberg ML.

J Immunol. 2003 May 1;170(9):4483-8.

21.

Intercellular adhesion molecule-1/LFA-1 ligation favors human Th1 development.

Smits HH, de Jong EC, Schuitemaker JH, Geijtenbeek TB, van Kooyk Y, Kapsenberg ML, Wierenga EA.

J Immunol. 2002 Feb 15;168(4):1710-6.

22.

Microbial compounds selectively induce Th1 cell-promoting or Th2 cell-promoting dendritic cells in vitro with diverse th cell-polarizing signals.

de Jong EC, Vieira PL, Kalinski P, Schuitemaker JH, Tanaka Y, Wierenga EA, Yazdanbakhsh M, Kapsenberg ML.

J Immunol. 2002 Feb 15;168(4):1704-9.

23.

How to deal with polarized Th2 cells: exploring the Achilles' heel.

Smits HH, Hilkens CM, Kalinski P, Kapsenberg ML, Wierenga EA.

Int Arch Allergy Immunol. 2001 Oct;126(2):102-10. Review.

PMID:
11729347
24.

Characterization of Toxoplasma gondii-specific T cells recovered from vitreous fluid of patients with ocular toxoplasmosis.

Feron EJ, Klaren VN, Wierenga EA, Verjans GM, Kijlstra A.

Invest Ophthalmol Vis Sci. 2001 Dec;42(13):3228-32.

PMID:
11726627
25.
26.

Silencer activity of NFATc2 in the interleukin-12 receptor beta 2 proximal promoter in human T helper cells.

van Rietschoten JG, Smits HH, van de Wetering D, Westland R, Verweij CL, den Hartog MT, Wierenga EA.

J Biol Chem. 2001 Sep 14;276(37):34509-16. Epub 2001 Jul 3.

27.

IL-12-induced reversal of human Th2 cells is accompanied by full restoration of IL-12 responsiveness and loss of GATA-3 expression.

Smits HH, van Rietschoten JG, Hilkens CM, Sayilir R, Stiekema F, Kapsenberg ML, Wierenga EA.

Eur J Immunol. 2001 Apr;31(4):1055-65.

28.

Regulation of interleukin 4 gene transcription: alterations in atopic disease?

Wierenga EA, Messer G.

Am J Respir Crit Care Med. 2000 Sep;162(3 Pt 2):S81-5. Review. No abstract available.

PMID:
10988157
29.

Atopic allergy: a failure of antigen-presenting cells to properly polarize helper T cells?

Kapsenberg ML, Hilkens CM, van Der Pouw Kraan TC, Wierenga EA, Kalinski P.

Am J Respir Crit Care Med. 2000 Sep;162(3 Pt 2):S76-80. Review. No abstract available.

PMID:
10988156
30.

Residual type 1 immunity in patients genetically deficient for interleukin 12 receptor beta1 (IL-12Rbeta1): evidence for an IL-12Rbeta1-independent pathway of IL-12 responsiveness in human T cells.

Verhagen CE, de Boer T, Smits HH, Verreck FA, Wierenga EA, Kurimoto M, Lammas DA, Kumararatne DS, Sanal O, Kroon FP, van Dissel JT, Sinigaglia F, Ottenhoff TH.

J Exp Med. 2000 Aug 21;192(4):517-28.

31.

IL-4 is a mediator of IL-12p70 induction by human Th2 cells: reversal of polarized Th2 phenotype by dendritic cells.

Kaliński P, Smits HH, Schuitemaker JH, Vieira PL, van Eijk M, de Jong EC, Wierenga EA, Kapsenberg ML.

J Immunol. 2000 Aug 15;165(4):1877-81.

32.

Development of Th1-inducing capacity in myeloid dendritic cells requires environmental instruction.

Vieira PL, de Jong EC, Wierenga EA, Kapsenberg ML, Kaliński P.

J Immunol. 2000 May 1;164(9):4507-12.

33.

Genomic organization of the human interleukin-12 receptor beta2-chain gene.

van Rietschoten JG, Smits HH, Westland R, Verweij CL, den Hartog MT, Wierenga EA.

Immunogenetics. 2000 Jan;51(1):30-6.

PMID:
10663559
34.

T-cell priming by type-1 and type-2 polarized dendritic cells: the concept of a third signal.

Kaliński P, Hilkens CM, Wierenga EA, Kapsenberg ML.

Immunol Today. 1999 Dec;20(12):561-7. Review. No abstract available.

PMID:
10562707
35.

The paradigm of type 1 and type 2 antigen-presenting cells. Implications for atopic allergy.

Kapsenberg ML, Hilkens CM, Wierenga EA, Kalinski P.

Clin Exp Allergy. 1999 Jun;29 Suppl 2:33-6. Review.

PMID:
10421820
38.

The role of antigen-presenting cells in the regulation of allergen-specific T cell responses.

Kapsenberg ML, Hilkens CM, Wierenga EA, Kalinski P.

Curr Opin Immunol. 1998 Dec;10(6):607-13. Review.

PMID:
9914218
39.
40.

Interleukin-17 and interferon-gamma synergize in the enhancement of proinflammatory cytokine production by human keratinocytes.

Teunissen MB, Koomen CW, de Waal Malefyt R, Wierenga EA, Bos JD.

J Invest Dermatol. 1998 Oct;111(4):645-9.

41.
42.

Immunodominant CD4+ T-cell epitope within nonstructural protein 3 in acute hepatitis C virus infection.

Diepolder HM, Gerlach JT, Zachoval R, Hoffmann RM, Jung MC, Wierenga EA, Scholz S, Santantonio T, Houghton M, Southwood S, Sette A, Pape GR.

J Virol. 1997 Aug;71(8):6011-9.

43.

Lack of IL-12 signaling in human allergen-specific Th2 cells.

Hilkens CM, Messer G, Tesselaar K, van Rietschoten AG, Kapsenberg ML, Wierenga EA.

J Immunol. 1996 Nov 15;157(10):4316-21.

PMID:
8906805
44.

Modulation of T-cell cytokine secretion by accessory cell-derived products.

Hilkens CM, Snijders A, Snijdewint FG, Wierenga EA, Kapsenberg ML.

Eur Respir J Suppl. 1996 Aug;22:90s-94s. Review.

PMID:
8871051
45.

Food allergen (peanut)-specific TH2 clones generated from the peripheral blood of a patient with peanut allergy.

de Jong EC, Spanhaak S, Martens BP, Kapsenberg ML, Penninks AH, Wierenga EA.

J Allergy Clin Immunol. 1996 Jul;98(1):73-81.

PMID:
8765820
46.

Production and modulation of T-cell cytokines in atopic allergy.

Kapsenberg ML, Hilkens CM, Jansen HM, Bos JD, Snijders A, Wierenga EA.

Int Arch Allergy Immunol. 1996 Jun;110(2):107-13. Review.

PMID:
8645987
47.

Accessory cell-derived IL-12 and prostaglandin E2 determine the IFN-gamma level of activated human CD4+ T cells.

Hilkens CM, Snijders A, Vermeulen H, van der Meide PH, Wierenga EA, Kapsenberg ML.

J Immunol. 1996 Mar 1;156(5):1722-27.

PMID:
8596019
48.

The role of accessory cell products in the regulation of T cell cytokine production.

Kapsenberg ML, Hilkens CM, van der Pouw Kraan TC, Wierenga EA, Snijders A.

Adv Exp Med Biol. 1996;409:305-8. Review. No abstract available.

PMID:
9095258
49.

Possible mechanism involving T-lymphocyte response to non-structural protein 3 in viral clearance in acute hepatitis C virus infection.

Diepolder HM, Zachoval R, Hoffmann RM, Wierenga EA, Santantonio T, Jung MC, Eichenlaub D, Pape GR.

Lancet. 1995 Oct 14;346(8981):1006-7.

PMID:
7475549
50.

Activation of a heterogeneous hepatitis B (HB) core and e antigen-specific CD4+ T-cell population during seroconversion to anti-HBe and anti-HBs in hepatitis B virus infection.

Jung MC, Diepolder HM, Spengler U, Wierenga EA, Zachoval R, Hoffmann RM, Eichenlaub D, Frösner G, Will H, Pape GR.

J Virol. 1995 Jun;69(6):3358-68.

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