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Items: 29

1.

Epidermal γδ T cells originate from yolk sac hematopoiesis and clonally self-renew in the adult.

Gentek R, Ghigo C, Hoeffel G, Jorquera A, Msallam R, Wienert S, Klauschen F, Ginhoux F, Bajénoff M.

J Exp Med. 2018 Nov 8. pii: jem.20181206. doi: 10.1084/jem.20181206. [Epub ahead of print]

PMID:
30409784
2.

[Standardized determination of tumor-infiltrating lymphocytes in breast cancer : A prognostic marker for histological diagnosis].

Denkert C, Loibl S, Budczies J, Wienert S, Klauschen F.

Pathologe. 2018 Nov;39(6):520-531. doi: 10.1007/s00292-018-0530-y. Review. German.

PMID:
30327858
3.

Morphology and tumour-infiltrating lymphocytes in high-stage, high-grade serous ovarian carcinoma correlated with long-term survival.

Darb-Esfahani S, Kolaschinski I, Trillsch F, Mahner S, Concin N, Vergote I, Van Nieuwenhuysen E, Achimas-Cadariu P, Glajzer J, Woopen H, Wienert S, Taube ET, Stanske M, Kulbe H, Denkert C, Sehouli J, Braicu EI.

Histopathology. 2018 Jul 14. doi: 10.1111/his.13711. [Epub ahead of print]

PMID:
30007074
4.

Scoring of tumor-infiltrating lymphocytes: From visual estimation to machine learning.

Klauschen F, Müller KR, Binder A, Bockmayr M, Hägele M, Seegerer P, Wienert S, Pruneri G, de Maria S, Badve S, Michiels S, Nielsen TO, Adams S, Savas P, Symmans F, Willis S, Gruosso T, Park M, Haibe-Kains B, Gallas B, Thompson AM, Cree I, Sotiriou C, Solinas C, Preusser M, Hewitt SM, Rimm D, Viale G, Loi S, Loibl S, Salgado R, Denkert C; International Immuno-Oncology Biomarker Working Group.

Semin Cancer Biol. 2018 Oct;52(Pt 2):151-157. doi: 10.1016/j.semcancer.2018.07.001. Epub 2018 Jul 7. Review.

PMID:
29990622
5.

Dynamics of the Intratumoral Immune Response during Progression of High-Grade Serous Ovarian Cancer.

Stanske M, Wienert S, Castillo-Tong DC, Kreuzinger C, Vergote I, Lambrechts S, Gabra H, Gourley C, Ganapathi RN, Kolaschinski I, Budczies J, Sehouli J, Ruscito I, Denkert C, Kulbe H, Schmitt W, Jöhrens K, Braicu I, Darb-Esfahani S.

Neoplasia. 2018 Mar;20(3):280-288. doi: 10.1016/j.neo.2018.01.007. Epub 2018 Feb 22.

6.

Update on tumor-infiltrating lymphocytes (TILs) in breast cancer, including recommendations to assess TILs in residual disease after neoadjuvant therapy and in carcinoma in situ: A report of the International Immuno-Oncology Biomarker Working Group on Breast Cancer.

Dieci MV, Radosevic-Robin N, Fineberg S, van den Eynden G, Ternes N, Penault-Llorca F, Pruneri G, D'Alfonso TM, Demaria S, Castaneda C, Sanchez J, Badve S, Michiels S, Bossuyt V, Rojo F, Singh B, Nielsen T, Viale G, Kim SR, Hewitt S, Wienert S, Loibl S, Rimm D, Symmans F, Denkert C, Adams S, Loi S, Salgado R; International Immuno-Oncology Biomarker Working Group on Breast Cancer.

Semin Cancer Biol. 2018 Oct;52(Pt 2):16-25. doi: 10.1016/j.semcancer.2017.10.003. Epub 2017 Oct 9. Review.

7.

T Cell Zone Resident Macrophages Silently Dispose of Apoptotic Cells in the Lymph Node.

Baratin M, Simon L, Jorquera A, Ghigo C, Dembele D, Nowak J, Gentek R, Wienert S, Klauschen F, Malissen B, Dalod M, Bajénoff M.

Immunity. 2017 Aug 15;47(2):349-362.e5. doi: 10.1016/j.immuni.2017.07.019. Epub 2017 Aug 8.

8.

Assessing Tumor-Infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method from the International Immuno-Oncology Biomarkers Working Group: Part 2: TILs in Melanoma, Gastrointestinal Tract Carcinomas, Non-Small Cell Lung Carcinoma and Mesothelioma, Endometrial and Ovarian Carcinomas, Squamous Cell Carcinoma of the Head and Neck, Genitourinary Carcinomas, and Primary Brain Tumors.

Hendry S, Salgado R, Gevaert T, Russell PA, John T, Thapa B, Christie M, van de Vijver K, Estrada MV, Gonzalez-Ericsson PI, Sanders M, Solomon B, Solinas C, Van den Eynden GGGM, Allory Y, Preusser M, Hainfellner J, Pruneri G, Vingiani A, Demaria S, Symmans F, Nuciforo P, Comerma L, Thompson EA, Lakhani S, Kim SR, Schnitt S, Colpaert C, Sotiriou C, Scherer SJ, Ignatiadis M, Badve S, Pierce RH, Viale G, Sirtaine N, Penault-Llorca F, Sugie T, Fineberg S, Paik S, Srinivasan A, Richardson A, Wang Y, Chmielik E, Brock J, Johnson DB, Balko J, Wienert S, Bossuyt V, Michiels S, Ternes N, Burchardi N, Luen SJ, Savas P, Klauschen F, Watson PH, Nelson BH, Criscitiello C, O'Toole S, Larsimont D, de Wind R, Curigliano G, André F, Lacroix-Triki M, van de Vijver M, Rojo F, Floris G, Bedri S, Sparano J, Rimm D, Nielsen T, Kos Z, Hewitt S, Singh B, Farshid G, Loibl S, Allison KH, Tung N, Adams S, Willard-Gallo K, Horlings HM, Gandhi L, Moreira A, Hirsch F, Dieci MV, Urbanowicz M, Brcic I, Korski K, Gaire F, Koeppen H, Lo A, Giltnane J, Rebelatto MC, Steele KE, Zha J, Emancipator K, Juco JW, Denkert C, Reis-Filho J, Loi S, Fox SB.

Adv Anat Pathol. 2017 Nov;24(6):311-335. doi: 10.1097/PAP.0000000000000161. Review.

9.

Assessing Tumor-infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method From the International Immunooncology Biomarkers Working Group: Part 1: Assessing the Host Immune Response, TILs in Invasive Breast Carcinoma and Ductal Carcinoma In Situ, Metastatic Tumor Deposits and Areas for Further Research.

Hendry S, Salgado R, Gevaert T, Russell PA, John T, Thapa B, Christie M, van de Vijver K, Estrada MV, Gonzalez-Ericsson PI, Sanders M, Solomon B, Solinas C, Van den Eynden GGGM, Allory Y, Preusser M, Hainfellner J, Pruneri G, Vingiani A, Demaria S, Symmans F, Nuciforo P, Comerma L, Thompson EA, Lakhani S, Kim SR, Schnitt S, Colpaert C, Sotiriou C, Scherer SJ, Ignatiadis M, Badve S, Pierce RH, Viale G, Sirtaine N, Penault-Llorca F, Sugie T, Fineberg S, Paik S, Srinivasan A, Richardson A, Wang Y, Chmielik E, Brock J, Johnson DB, Balko J, Wienert S, Bossuyt V, Michiels S, Ternes N, Burchardi N, Luen SJ, Savas P, Klauschen F, Watson PH, Nelson BH, Criscitiello C, O'Toole S, Larsimont D, de Wind R, Curigliano G, André F, Lacroix-Triki M, van de Vijver M, Rojo F, Floris G, Bedri S, Sparano J, Rimm D, Nielsen T, Kos Z, Hewitt S, Singh B, Farshid G, Loibl S, Allison KH, Tung N, Adams S, Willard-Gallo K, Horlings HM, Gandhi L, Moreira A, Hirsch F, Dieci MV, Urbanowicz M, Brcic I, Korski K, Gaire F, Koeppen H, Lo A, Giltnane J, Rebelatto MC, Steele KE, Zha J, Emancipator K, Juco JW, Denkert C, Reis-Filho J, Loi S, Fox SB.

Adv Anat Pathol. 2017 Sep;24(5):235-251. doi: 10.1097/PAP.0000000000000162. Review.

10.

15 years of the histopathological synovitis score, further development and review: A diagnostic score for rheumatology and orthopaedics.

Krenn V, Perino G, Rüther W, Krenn VT, Huber M, Hügle T, Najm A, Müller S, Boettner F, Pessler F, Waldstein W, Kriegsmann J, Casadonte R, Häupl T, Wienert S, Krukemeyer MG, Sesselmann S, Sunitsch S, Tikhilov R, Morawietz L.

Pathol Res Pract. 2017 Aug;213(8):874-881. doi: 10.1016/j.prp.2017.05.005. Epub 2017 May 19. Review.

PMID:
28687159
11.

[Fifteen years of the histopathological synovitis score : Review and further developments of a diagnostic score].

Krenn V, Perino G, Rüther W, Krenn VT, Huber M, Hügle T, Najm A, Müller S, Boettner F, Pessler F, Waldstein W, Kriegsmann J, Häupl T, Wienert S, Krukemeyer MG, Sesselmann S, Tikhilov R, Morawietz L.

Z Rheumatol. 2017 Aug;76(6):539-546. doi: 10.1007/s00393-017-0308-2. Review. German.

PMID:
28470440
12.

Clonal Proliferation and Stochastic Pruning Orchestrate Lymph Node Vasculature Remodeling.

Mondor I, Jorquera A, Sene C, Adriouch S, Adams RH, Zhou B, Wienert S, Klauschen F, Bajénoff M.

Immunity. 2016 Oct 18;45(4):877-888. doi: 10.1016/j.immuni.2016.09.017.

13.

Fibrosis in low-grade follicular lymphoma - a link to the TH2 immune reaction.

Lohneis P, Wienert S, Klauschen F, Anagnostopoulos I, Jöhrens K.

Leuk Lymphoma. 2017 May;58(5):1190-1196. doi: 10.1080/10428194.2016.1231404. Epub 2016 Oct 13.

PMID:
27736316
14.

Standardized evaluation of tumor-infiltrating lymphocytes in breast cancer: results of the ring studies of the international immuno-oncology biomarker working group.

Denkert C, Wienert S, Poterie A, Loibl S, Budczies J, Badve S, Bago-Horvath Z, Bane A, Bedri S, Brock J, Chmielik E, Christgen M, Colpaert C, Demaria S, Van den Eynden G, Floris G, Fox SB, Gao D, Ingold Heppner B, Kim SR, Kos Z, Kreipe HH, Lakhani SR, Penault-Llorca F, Pruneri G, Radosevic-Robin N, Rimm DL, Schnitt SJ, Sinn BV, Sinn P, Sirtaine N, O'Toole SA, Viale G, Van de Vijver K, de Wind R, von Minckwitz G, Klauschen F, Untch M, Fasching PA, Reimer T, Willard-Gallo K, Michiels S, Loi S, Salgado R.

Mod Pathol. 2016 Oct;29(10):1155-64. doi: 10.1038/modpathol.2016.109. Epub 2016 Jul 1.

15.

[Histopathological diagnostic work-up of joint endoprosthesis-associated pathologies].

Krenn V, Perino G, Krenn VT, Wienert S, Saberi D, Hügle T, Hopf F, Huber M.

Hautarzt. 2016 May;67(5):365-72. doi: 10.1007/s00105-016-3778-2. Review. German.

PMID:
26987961
16.

Prognostic impact of programmed cell death-1 (PD-1) and PD-ligand 1 (PD-L1) expression in cancer cells and tumor-infiltrating lymphocytes in ovarian high grade serous carcinoma.

Darb-Esfahani S, Kunze CA, Kulbe H, Sehouli J, Wienert S, Lindner J, Budczies J, Bockmayr M, Dietel M, Denkert C, Braicu I, Jöhrens K.

Oncotarget. 2016 Jan 12;7(2):1486-99. doi: 10.18632/oncotarget.6429.

17.

Strategies for developing Ki67 as a useful biomarker in breast cancer.

Denkert C, Budczies J, von Minckwitz G, Wienert S, Loibl S, Klauschen F.

Breast. 2015 Nov;24 Suppl 2:S67-72. doi: 10.1016/j.breast.2015.07.017. Epub 2015 Aug 14. Review.

PMID:
26283598
18.

[CD15 focus score for diagnostics of periprosthetic joint infections : Neutrophilic granulocytes quantification mode and the development of morphometric software (CD15 quantifier)].

Kölbel B, Wienert S, Dimitriadis J, Kendoff D, Gehrke T, Huber M, Frommelt L, Tiemann A, Saeger K, Krenn V.

Z Rheumatol. 2015 Sep;74(7):622-30. doi: 10.1007/s00393-015-1571-8. German.

PMID:
25869074
19.

[Revision arthroplasty : Histopathological diagnostics in periprosthetic joint infections].

Krenn V, Kölbel B, Huber M, Tiemann A, Kendoff D, Wienert S, Boettner F, Gehrke T.

Orthopade. 2015 May;44(5):349-56. doi: 10.1007/s00132-015-3083-2. German.

PMID:
25731144
20.

Tumor-infiltrating lymphocytes and response to neoadjuvant chemotherapy with or without carboplatin in human epidermal growth factor receptor 2-positive and triple-negative primary breast cancers.

Denkert C, von Minckwitz G, Brase JC, Sinn BV, Gade S, Kronenwett R, Pfitzner BM, Salat C, Loi S, Schmitt WD, Schem C, Fisch K, Darb-Esfahani S, Mehta K, Sotiriou C, Wienert S, Klare P, André F, Klauschen F, Blohmer JU, Krappmann K, Schmidt M, Tesch H, Kümmel S, Sinn P, Jackisch C, Dietel M, Reimer T, Untch M, Loibl S.

J Clin Oncol. 2015 Mar 20;33(9):983-91. doi: 10.1200/JCO.2014.58.1967. Epub 2014 Dec 22.

PMID:
25534375
21.

Standardized Ki67 Diagnostics Using Automated Scoring--Clinical Validation in the GeparTrio Breast Cancer Study.

Klauschen F, Wienert S, Schmitt WD, Loibl S, Gerber B, Blohmer JU, Huober J, Rüdiger T, Erbstößer E, Mehta K, Lederer B, Dietel M, Denkert C, von Minckwitz G.

Clin Cancer Res. 2015 Aug 15;21(16):3651-7. doi: 10.1158/1078-0432.CCR-14-1283. Epub 2014 Dec 11.

22.

The evaluation of tumor-infiltrating lymphocytes (TILs) in breast cancer: recommendations by an International TILs Working Group 2014.

Salgado R, Denkert C, Demaria S, Sirtaine N, Klauschen F, Pruneri G, Wienert S, Van den Eynden G, Baehner FL, Penault-Llorca F, Perez EA, Thompson EA, Symmans WF, Richardson AL, Brock J, Criscitiello C, Bailey H, Ignatiadis M, Floris G, Sparano J, Kos Z, Nielsen T, Rimm DL, Allison KH, Reis-Filho JS, Loibl S, Sotiriou C, Viale G, Badve S, Adams S, Willard-Gallo K, Loi S; International TILs Working Group 2014.

Ann Oncol. 2015 Feb;26(2):259-71. doi: 10.1093/annonc/mdu450. Epub 2014 Sep 11.

PMID:
25214542
23.

Fate mapping reveals origin and dynamics of lymph node follicular dendritic cells.

Jarjour M, Jorquera A, Mondor I, Wienert S, Narang P, Coles MC, Klauschen F, Bajénoff M.

J Exp Med. 2014 Jun 2;211(6):1109-22. doi: 10.1084/jem.20132409. Epub 2014 May 26.

24.

Multicolor fate mapping of Langerhans cell homeostasis.

Ghigo C, Mondor I, Jorquera A, Nowak J, Wienert S, Zahner SP, Clausen BE, Luche H, Malissen B, Klauschen F, Bajénoff M.

J Exp Med. 2013 Aug 26;210(9):1657-64. doi: 10.1084/jem.20130403. Epub 2013 Aug 12.

25.

Marginal zone lymphomas with monocytoid morphology express T-bet and are associated with a low number of T cells in extranodal locations.

Lohneis P, Wienert S, Klauschen F, Ullrich A, Anagnostopoulos I, Jöhrens K.

Leuk Lymphoma. 2014 Jan;55(1):143-8. doi: 10.3109/10428194.2013.797082. Epub 2013 Jun 4.

PMID:
23607257
26.

CognitionMaster: an object-based image analysis framework.

Wienert S, Heim D, Kotani M, Lindequist B, Stenzinger A, Ishii M, Hufnagl P, Beil M, Dietel M, Denkert C, Klauschen F.

Diagn Pathol. 2013 Feb 27;8:34. doi: 10.1186/1746-1596-8-34.

27.

Detection and segmentation of cell nuclei in virtual microscopy images: a minimum-model approach.

Wienert S, Heim D, Saeger K, Stenzinger A, Beil M, Hufnagl P, Dietel M, Denkert C, Klauschen F.

Sci Rep. 2012;2:503. doi: 10.1038/srep00503. Epub 2012 Jul 11.

28.

Integration and acceleration of virtual microscopy as the key to successful implementation into the routine diagnostic process.

Wienert S, Beil M, Saeger K, Hufnagl P, Schrader T.

Diagn Pathol. 2009 Jan 9;4:3. doi: 10.1186/1746-1596-4-3.

29.

Facets of lupus erythematosus: panniculitis responding to thalidomide.

Wienert S, Gadola S, Hunziker T.

J Dtsch Dermatol Ges. 2008 Mar;6(3):214-6. Epub 2007 Dec 11. English, German.

PMID:
18076656

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